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Erwin Neher
Erwin Neher (; ; born 20 March 1944) is a German biophysicist, specializing in the field of cell physiology. For significant contribution in the field, in 1991 he was awarded, along with Bert Sakmann, the Nobel Prize in Physiology or Medicine for "their discoveries concerning the function of single ion channels in cells". Early life and education Neher was born in Landsberg am Lech, Upper Bavaria, the son of Elisabeth (née Pfeiffer), a teacher, and Franz Xaver Neher, an executive at a dairy company. He studied physics at the Technical University of Munich from 1963 to 1966. In 1966, he was awarded a Fulbright Scholarship to study in the US. He spent a year at the University of Wisconsin–Madison, and earned a master's degree in biophysics. While at the Charles Stevens Laboratory at Yale University for post-doctoral work he met fellow scientist Eva-Maria Neher, whom he married in 1978 and subsequently the couple had five children – Richard, Benjamin, Carola, Sigmund, and Margr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Landsberg Am Lech
Landsberg am Lech (Landsberg at the Lech) is a town in southwest Bavaria, Germany, about 65 kilometers west of Munich and 35 kilometers south of Augsburg. It is the capital of the district of Landsberg am Lech. Overview Landsberg is situated on the Romantic Road and is the center of the Lechrain region, the boundary region between Swabia and Bavaria. It is noted for its picturesque historic center. Landsberg am Lech developed where a major historic salt road crossed over the Lech. To protect the bridge, Duke Henry the Lion ordered a castle to be built, ''Castrum Landespurch'', incorporating an older settlement and castle named ''Phetine''. Soon a greater settlement evolved, which received its town charter as early as the 13th century. In 1315, the town burned down, but was rebuilt because of its important location. In 1320, Landsberg was permitted to collect salt duties, bringing considerable wealth to the town. In 1419, a river tax added a further source of income. The town ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Physiology
Cell physiology is the biological study of the activities that take place in a cell to keep it alive. The term ''physiology'' refers to normal functions in a living organism. Animal cells, plant cells and microorganism cells show similarities in their functions even though they vary in structure. General characteristics There are two types of cells: prokaryotes and eukaryotes. Prokaryotes were the first of the two to develop and do not have a self-contained nucleus. Their mechanisms are simpler than later-evolved eukaryotes, which contain a nucleus that envelops the cell's DNA and some organelles. Prokaryotes Prokaryotes have DNA located in an area called the nucleoid, which is not separated from other parts of the cell by a membrane. There are two domains of prokaryotes: bacteria and archaea. Prokaryotes have fewer organelles than eukaryotes. Both have plasma membranes and ribosomes (structures that synthesize proteins and float free in cytoplasm). Two unique characteristics ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ralph W
Ralph (pronounced ; or ,) is a male given name of English, Scottish and Irish origin, derived from the Old English ''Rædwulf'' and Radulf, cognate with the Old Norse ''Raðulfr'' (''rað'' "counsel" and ''ulfr'' "wolf"). The most common forms are: * Ralph, the common variant form in English, which takes either of the given pronunciations. * Rafe, variant form which is less common; this spelling is always pronounced , as are all other English spellings without "l". * Raife, a very rare variant. * Raif, a very rare variant. Raif Rackstraw from H.M.S. Pinafore * Ralf, the traditional variant form in Dutch, German, Swedish, and Polish. * Ralfs, the traditional variant form in Latvian. * Raoul, the traditional variant form in French. * Raúl, the traditional variant form in Spanish. * Raul, the traditional variant form in Portuguese and Italian. * Raül, the traditional variant form in Catalan. * Rádhulbh, the traditional variant form in Irish. Given name Middle Ages * Ralp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Göttingen
Göttingen (, , ; nds, Chöttingen) is a college town, university city in Lower Saxony, central Germany, the Capital (political), capital of Göttingen (district), the eponymous district. The River Leine runs through it. At the end of 2019, the population was 118,911. General information The origins of Göttingen lay in a village called ''Gutingi, ''first mentioned in a document in 953 AD. The city was founded northwest of this village, between 1150 and 1200 AD, and adopted its name. In Middle Ages, medieval times the city was a member of the Hanseatic League and hence a wealthy town. Today, Göttingen is famous for its old university (''Georgia Augusta'', or University of Göttingen, "Georg-August-Universität"), which was founded in 1734 (first classes in 1737) and became the most visited university of Europe. In 1837, seven professors protested against the absolute sovereignty of the House of Hanover, kings of Kingdom of Hanover, Hanover; they lost their positions, but be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Postdoctoral Research
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to pursue additional research, training, or teaching in order to have better skills to pursue a career in academia, research, or any other field. Postdocs often, but not always, have a temporary academic appointment, sometimes in preparation for an academic faculty position. They continue their studies or carry out research and further increase expertise in a specialist subject, including integrating a team and acquiring novel skills and research methods. Postdoctoral research is often considered essential while advancing the scholarly mission of the host institution; it is expected to produce relevant publications in peer-reviewed academic journals or conferences. In some countries, postdoctoral research may lead to further formal qualificati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Patch-clamp Technique
The patch clamp technique is a laboratory technique in electrophysiology used to study ionic currents in individual Cell isolation, isolated living cells, tissue sections, or patches of cell membrane. The technique is especially useful in the study of excitable cells such as neurons, cardiomyocytes, muscle fibers, and pancreas, pancreatic beta cells, and can also be applied to the study of bacterial ion channels in specially prepared giant spheroplasts. Patch clamping can be performed using the voltage clamp technique. In this case, the voltage across the cell membrane is controlled by the experimenter and the resulting currents are recorded. Alternatively, the Electrophysiology, current clamp technique can be used. In this case, the current passing across the membrane is controlled by the experimenter and the resulting changes in voltage are recorded, generally in the form of action potentials. Erwin Neher and Bert Sakmann developed the patch clamp in the late 1970s and earl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ion Channels
Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore. Their functions include establishing a resting membrane potential, shaping action potentials and other electrical signals by gating the flow of ions across the cell membrane, controlling the flow of ions across secretory and epithelial cells, and regulating cell volume. Ion channels are present in the membranes of all cells. Ion channels are one of the two classes of ionophoric proteins, the other being ion transporters. The study of ion channels often involves biophysics, electrophysiology, and pharmacology, while using techniques including voltage clamp, patch clamp, immunohistochemistry, X-ray crystallography, fluoroscopy, and RT-PCR. Their classification as molecules is referred to as channelomics. Basic features There are two distinctive features of ion channels that differentiate them from other types of ion transporter proteins: #The rate of ion transport through the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deutsche Forschungsgemeinschaft
The German Research Foundation (german: Deutsche Forschungsgemeinschaft ; DFG ) is a German research funding organization, which functions as a self-governing institution for the promotion of science and research in the Federal Republic of Germany. In 2019, the DFG had a funding budget of €3.3 billion. Function The DFG supports research in science, engineering, and the humanities through a variety of grant programmes, research prizes, and by funding infrastructure. The self-governed organization is based in Bonn and financed by the German states and the federal government of Germany. As of 2017, the organization consists of approximately 100 research universities and other research institutions. The DFG endows various research prizes, including the Leibniz Prize. The Polish-German science award Copernicus Award, Copernicus is offered jointly with the Foundation for Polish Science. According to a 2017 article in ''The Guardian'', the DFG has announced it will publish its re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Columbia University
Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhattan, Columbia is the oldest institution of higher education in New York and the fifth-oldest institution of higher learning in the United States. It is one of nine colonial colleges founded prior to the Declaration of Independence. It is a member of the Ivy League. Columbia is ranked among the top universities in the world. Columbia was established by royal charter under George II of Great Britain. It was renamed Columbia College in 1784 following the American Revolution, and in 1787 was placed under a private board of trustees headed by former students Alexander Hamilton and John Jay. In 1896, the campus was moved to its current location in Morningside Heights and renamed Columbia University. Columbia scientists and scholars have ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Humanism And Its Aspirations
''Humanism and Its Aspirations'' (subtitled ''Humanist Manifesto III, a successor to the Humanist Manifesto of 1933'') is the most recent of the ''Humanist Manifestos'', published in 2003 by the American Humanist Association (AHA). The newest one is much shorter, listing six primary beliefs, which echo themes from its predecessors: * Knowledge of the world is derived by observation, experimentation, and rational analysis. (See empiricism.) * Humans are an integral part of nature, the result of unguided evolutionary change. * Ethical values are derived from human need and interest as tested by experience. (See ethical naturalism.) * Life's fulfillment emerges from individual participation in the service of humane ideals. * Humans are social by nature and find meaning in relationships. * Working to benefit society maximizes individual happiness. It has been used as source material for secular and atheist ethics. Signatories The following academics and other prominent persons w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eva-Maria Neher
Eva-Maria Neher (née Ruhr, born 22 November 1950) is a German scientist in the fields of biochemistry and microbiology. She founded the Göttingen Xlab and has been its Executive Director since 2000. The Göttingen Xlab is an experimental laboratory for training young people from student to scientist level. She is married to Erwin Neher who is a Nobel laureate for his Nobel Prize in Physiology or Medicine. She is the recipient of many awards including the Lower Saxony State Prize. Biography Neher was born in Mülheim, Germany. Her initial academic education as an undergraduate in microbiology was from 1969 to 1973 at the University of Göttingen. She received her diploma in biology in 1974, earning a PhD on biochemistry from the same university; her thesis was ''Regulation of the biosynthesis of poly-beta-hydroxybutyrate in Alcaligenes eutrophus H 16''. She then worked in the same university as a staff scientist in 1977. From 1977–78 she also undertook postdoctoral research ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fulbright Scholarship
The Fulbright Program, including the Fulbright–Hays Program, is one of several United States Cultural Exchange Programs with the goal of improving intercultural relations, cultural diplomacy, and intercultural competence between the people of the United States and other countries, through the exchange of persons, knowledge, and skills. Via the program, competitively-selected American citizens including students, scholars, teachers, professionals, scientists, and artists may receive scholarships or grants to study, conduct research, teach, or exercise their talents abroad; and citizens of other countries may qualify to do the same in the United States. The program was founded by United States Senator J. William Fulbright in 1946 and is considered to be one of the most widely recognized and prestigious scholarships in the world. The program provides approximately 8,000 grants annually – roughly 1,600 to U.S. students, 1,200 to U.S. scholars, 4,000 to foreign students, 900 to fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
