Ernst T. Krebs
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Ernst T. Krebs
Ernst Theodore Krebs, Jr. (May 17, 1911 – September 8, 1996), known as Ernst T. Krebs, was a notorious American conman who promoted various substances as alternative cures for cancer, including pangamic acid and amygdalin. He also co-patented the semi-synthetic chemical compound closely related to amygdalin named laetrile, which was also promoted as a cancer preventative and cure. His medical claims about these compounds are not supported by scientific evidence and are widely considered quackery. Biography Krebs was born in Carson City, Nevada, on May 17, 1911. His father was Ernst Theodore Krebs, Sr. (September 26, 1876 – January 25, 1970), a physician who promoted a syrup as treatment for various ailments which was later deemed fraudulent, seized, and destroyed, and later promoted the enzyme chymotrypsin as a cancer remedy. Krebs, Jr. would ultimately work closely with his father in promoting Laetrile and pangamic acid. Krebs attended Hahnemann Medical College for th ...
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Hans Krebs (biochemist)
Sir Hans Adolf Krebs, FRS (, ; 25 August 1900 – 22 November 1981) was a German-born British biologist, physician and biochemist. He was a pioneer scientist in the study of cellular respiration, a biochemical process in living cells that extracts energy from food and oxygen and makes it available to drive the processes of life. He is best known for his discoveries of two important sequences of chemical reactions that take place in the cells of humans and many other organisms, namely the citric acid cycle and the urea cycle. The former, often eponymously known as the "Krebs cycle", is the key sequence of metabolic reactions that provides energy in the cells of humans and other oxygen-respiring organisms; and its discovery earned Krebs a Nobel Prize in Physiology or Medicine in 1953. With Hans Kornberg, he also discovered the glyoxylate cycle, which is a slight variation of the citric acid cycle found in plants, bacteria, protists, and fungi. Krebs died in 1981 in Oxford, wh ...
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Honorary Degree
An honorary degree is an academic degree for which a university (or other degree-awarding institution) has waived all of the usual requirements. It is also known by the Latin phrases ''honoris causa'' ("for the sake of the honour") or ''ad honorem '' ("to the honour"). The degree is typically a doctorate or, less commonly, a master's degree, and may be awarded to someone who has no prior connection with the academic institution or no previous postsecondary education. An example of identifying a recipient of this award is as follows: Doctorate in Business Administration (''Hon. Causa''). The degree is often conferred as a way of honouring a distinguished visitor's contributions to a specific field or to society in general. It is sometimes recommended that such degrees be listed in one's curriculum vitae (CV) as an award, and not in the education section. With regard to the use of this honorific, the policies of institutions of higher education generally ask that recipients ...
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Almond
The almond (''Prunus amygdalus'', syn. ''Prunus dulcis'') is a species of tree native to Iran and surrounding countries, including the Levant. The almond is also the name of the edible and widely cultivated seed of this tree. Within the genus ''Prunus'', it is classified with the peach in the subgenus ''Amygdalus'', distinguished from the other subgenera by corrugations on the shell (endocarp) surrounding the seed. The fruit of the almond is a drupe, consisting of an outer hull and a hard shell with the seed, which is not a true nut. ''Shelling'' almonds refers to removing the shell to reveal the seed. Almonds are sold shelled or unshelled. Blanched almonds are shelled almonds that have been treated with hot water to soften the seedcoat, which is then removed to reveal the white embryo. Once almonds are cleaned and processed, they can be stored over time. Almonds are used in many food cuisines, often featuring prominently in desserts, such as marzipan. The almond tree p ...
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Glycoside
In chemistry, a glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. These can be activated by enzyme hydrolysis, which causes the sugar part to be broken off, making the chemical available for use. Many such plant glycosides are used as medications. Several species of ''Heliconius'' butterfly are capable of incorporating these plant compounds as a form of chemical defense against predators. In animals and humans, poisons are often bound to sugar molecules as part of their elimination from the body. In formal terms, a glycoside is any molecule in which a sugar group is bonded through its anomeric carbon to another group via a glycosidic bond. Glycosides can be linked by an O- (an ''O-glycoside''), N- (a ''glycosylamine''), S-(a ''thioglycoside''), or C- (a '' C-glycoside'') glycosidic bond. According to th ...
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The American Journal Of Clinical Nutrition
''The American Journal of Clinical Nutrition'' (''AJCN'') is a monthly peer-reviewed biomedical journal in the fields of dietetics and clinical nutrition. The journal was established in 1952 as the ''Journal of Clinical Nutrition'', edited by S.O. Waife and published by the Nutrition Press. It was continued in series under the present title from 1954 and was published by the American Society for Clinical Nutrition (ASCN).Catalog entry
at the .
It is now published by the .< ...
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Vitamin
A vitamin is an organic molecule (or a set of molecules closely related chemically, i.e. vitamers) that is an Nutrient#Essential nutrients, essential micronutrient that an organism needs in small quantities for the proper functioning of its metabolism. Essential nutrients cannot be biosynthesis, synthesized in the organism, either at all or not in sufficient quantities, and therefore must be obtained through the Diet (nutrition), diet. Vitamin C can be synthesized by some species but not by others; it is not a vitamin in the first instance but is in the second. The term ''vitamin'' does not include the three other groups of essential nutrients: mineral (nutrient), minerals, essential fatty acids, and essential amino acids. Most vitamins are not single molecules, but groups of related molecules called vitamers. For example, there are eight vitamers of vitamin E: four tocopherols and four tocotrienols. Some sources list fourteen vitamins, by including choline, but major health ...
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Embryologist
Embryology (from Greek ἔμβρυον, ''embryon'', "the unborn, embryo"; and -λογία, '' -logia'') is the branch of animal biology that studies the prenatal development of gametes (sex cells), fertilization, and development of embryos and fetuses. Additionally, embryology encompasses the study of congenital disorders that occur before birth, known as teratology. Early embryology was proposed by Marcello Malpighi, and known as preformationism, the theory that organisms develop from pre-existing miniature versions of themselves. Aristotle proposed the theory that is now accepted, epigenesis. Epigenesis is the idea that organisms develop from seed or egg in a sequence of steps. Modern embryology, developed from the work of Karl Ernst von Baer, though accurate observations had been made in Italy by anatomists such as Aldrovandi and Leonardo da Vinci in the Renaissance. Comparative embryology Preformationism and epigenesis As recently as the 18th century, the prevailin ...
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Trophoblasts
The trophoblast (from Greek : to feed; and : germinator) is the outer layer of cells of the blastocyst. Trophoblasts are present four days after fertilization in humans. They provide nutrients to the embryo and develop into a large part of the placenta. They form during the first stage of pregnancy and are the first cells to differentiate from the fertilized egg to become extraembryonic structures that do not directly contribute to the embryo. After gastrulation, the trophoblast is contiguous with the ectoderm of the embryo and is referred to as the trophectoderm. After the first differentiation, the cells in the human embryo lose their totipotency and are no longer totipotent stem cells because they cannot form a trophoblast. They are now pluripotent stem cells. Structure The trophoblast proliferates and differentiates into two cell layers at approximately six days after fertilization for humans. Function Trophoblasts are specialized cells of the placenta that play ...
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Carcinogenesis
Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by changes at the cellular, genetic, and epigenetic levels and abnormal cell division. Cell division is a physiological process that occurs in almost all tissues and under a variety of circumstances. Normally, the balance between proliferation and programmed cell death, in the form of apoptosis, is maintained to ensure the integrity of tissues and organs. According to the prevailing accepted theory of carcinogenesis, the somatic mutation theory, mutations in DNA and epimutations that lead to cancer disrupt these orderly processes by interfering with the programming regulating the processes, upsetting the normal balance between proliferation and cell death. This results in uncontrolled cell division and the evolution of those cells by natural selection in the body. Only certain mutations lead to cancer w ...
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John Beard (embryologist)
John Beard (11 November 1858 – 24 November 1924) was a Scottish embryologist, known for his controversial theory of the trophoblastic origin of cancer and his experimental treatments of cancer by means of pancreatic enzymes. Early life and education Beard was born on 11 November 1858 in Heaton Norris, a "southern suburb of industrial Manchester, UK." Beard hailed from a family of mill workers; his grandfather was an unskilled laborer while his father rose to the position of mill clerk. Although uneducated, his father did well enough to rent a home in Reddish Lane, a white collar neighborhood with a live-in servant. The family's fortunes took a turn for the worse in 1866 when his father died at 31 years old. Although his mother (Eliza) still had some means, the family moved to a blue-collar neighborhood to adjust to the increased financial hardship. These issues proved temporary, however, when Eliza married a cotton manufacturer which moved the family to Littleborough, Rochda ...
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Krebs Cycle
The citric acid cycle (CAC)—also known as the Krebs cycle or the TCA cycle (tricarboxylic acid cycle)—is a series of chemical reactions to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins. The Krebs cycle is used by organisms that respire (as opposed to organisms that ferment) to generate energy, either by anaerobic respiration or aerobic respiration. In addition, the cycle provides precursors of certain amino acids, as well as the reducing agent NADH, that are used in numerous other reactions. Its central importance to many biochemical pathways suggests that it was one of the earliest components of metabolism and may have originated abiogenically. Even though it is branded as a 'cycle', it is not necessary for metabolites to follow only one specific route; at least three alternative segments of the citric acid cycle have been recognized. The name of this metabolic pathway is derived from the citric acid (a tricarbo ...
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Hans Adolf Krebs
Sir Hans Adolf Krebs, FRS (, ; 25 August 1900 – 22 November 1981) was a German-born British biologist, physician and biochemist. He was a pioneer scientist in the study of cellular respiration, a biochemical process in living cells that extracts energy from food and oxygen and makes it available to drive the processes of life. He is best known for his discoveries of two important sequences of chemical reactions that take place in the cells of humans and many other organisms, namely the citric acid cycle and the urea cycle. The former, often eponymously known as the "Krebs cycle", is the key sequence of metabolic reactions that provides energy in the cells of humans and other oxygen-respiring organisms; and its discovery earned Krebs a Nobel Prize in Physiology or Medicine in 1953. With Hans Kornberg, he also discovered the glyoxylate cycle, which is a slight variation of the citric acid cycle found in plants, bacteria, protists, and fungi. Krebs died in 1981 in Oxford, wh ...
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