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Epsiprantel
Epsiprantel (trade name Cestex) is a veterinary drug which is used as an anthelmintic against tapeworms such as ''Echinococcus granulosus''. Indications It is indicated for the removal of cestodes (tapeworms) in cats (''Dipylidium caninum'' and ''Taenia taeniaeformis'') and dogs (''Dipylidium caninum'' and ''Taenia pisiformis ''Taenia pisiformis'', commonly called the rabbit tapeworm, is an endoparasite, endoparasitic tapeworm which causes infection in lagomorphs, rodents, and carnivores. Adult ''T. pisiformis'' typically occur within the small intestines of the defi ...'') 7 weeks of age and older. References Anthelmintics Veterinary drugs Benzazepanes Heterocyclic compounds with 3 rings Cyclohexyl compounds {{antiinfective-drug-stub ...
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Taenia Pisiformis
''Taenia pisiformis'', commonly called the rabbit tapeworm, is an endoparasitic tapeworm which causes infection in lagomorphs, rodents, and carnivores. Adult ''T. pisiformis'' typically occur within the small intestines of the definitive hosts, the carnivores. Lagomorphs, the intermediate hosts, are infected by fecal contamination of grasses and other food sources by the definitive hosts. The larval stage is often referred to as ''Cysticercus pisiformis'' and is found on the livers and peritoneal cavities of the intermediate hosts. ''T. pisiformis'' can be found worldwide. Description ''T. pisiformis'' typically infect dogs and other carnivores such as coyotes and foxes. In rabbits, ''T. pisiformis'' larvae attach themselves to the liver and intestines, forming cysts in diameter. This is referred to as cysticercosis. In adult ''T. pisiformis'', the long hooks of the scolex are on average and the short hooks are . The dimensions of the suckers are . They can have from 34 to ...
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Oral Administration
Oral administration is a route of administration where a substance is taken through the mouth. Per os abbreviated to P.O. is sometimes used as a direction for medication to be taken orally. Many medications are taken orally because they are intended to have a systemic effect, reaching different parts of the body via the bloodstream, for example. Oral administration can be easier and less painful than other routes, such as injection. However, the onset of action is relatively low, and the effectiveness is reduced if it is not absorbed properly in the digestive system, or if it is broken down by digestive enzymes before it can reach the bloodstream. Some medications may cause gastrointestinal side effects, such as nausea or vomiting, when taken orally. Oral administration can also only be applied to conscious patients, and patients willing and able to swallow. Terminology ''Per os'' (; ''P.O.'') is an adverbial phrase meaning literally from Latin "through the mouth" or "by mouth ...
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Veterinary Drug
An animal drug (also veterinary drug) refers to a drug intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in animals. Regulation United States The U.S. Food and Drug Administration (FDA) has the broad mandate under the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 321 et seq.) to assure the safety and effectiveness of animal drugs and their use in all animals, including farm animals. The division of the FDA responsible for this is the Center for Veterinary Medicine (CVM). The equivalents of the Investigational New Drug and New Drug Application are known as the Investigational New Animal Drug and New Animal Drug Application, respectively. Before CVM formally approves an animal drug, the sponsor or manufacturer of the drug must document in scientific testing that the drug has been found "safe and effective". The testing data also must demonstrate that a methodology is available to detect and measure any residue left in edible animal produ ...
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Anthelmintic
Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. They may also be called vermifuges (those that stun) or vermicides (those that kill). Anthelmintics are used to treat people who are infected by helminths, a condition called helminthiasis. These drugs are also used to treat infected animals. Pills containing anthelmintics are used in mass deworming campaigns of school-aged children in many developing countries. The drugs of choice for soil-transmitted helminths are mebendazole and albendazole; for schistosomiasis and tapeworms it is praziquantel. Types Antiparasitics that specifically target worms of the genus ''Ascaris'' are called ascaricides. * Benzimidazoles: ** Albendazole – effective against threadworms, roundworms, whipworms, tapeworms, hookworms ** Mebendazole – effective against v ...
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Tapeworm
Eucestoda, commonly referred to as tapeworms, is the larger of the two subclasses of flatworms in the class Cestoda (the other subclass is Cestodaria). Larvae have six posterior hooks on the scolex (head), in contrast to the ten-hooked Cestodaria. All tapeworms are endoparasites of vertebrates, living in the digestive tract or related ducts. Examples are the pork tapeworm (''Taenia solium'') with a human definitive host, and pigs as the secondary host, and ''Moniezia expansa'', the definitive hosts of which are ruminants. Body structure Adult Eucestoda have a white-opaque dorso-ventrally flattened appearance, and are elongated, ranging in length from a few millimeters to 25 meters. Almost all members, except members of the orders Caryophyllidea and Spathebothriidea, are polyzoic with repeated sets of reproductive organs down the body length, and almost all members, except members of the order Dioecocestidae, are protandral hermaphrodites. Most except caryophyllideans consist ...
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Echinococcus Granulosus
''Echinococcus granulosus,'' also called the hydatid worm, hyper tape-worm or dog tapeworm, is a cyclophyllid cestode that dwells in the small intestine of canids as an adult, but which has important intermediate hosts such as livestock and humans, where it causes cystic echinococcosis, also known as hydatid disease. The adult tapeworm ranges in length from 3 mm to 6 mm and has three proglottids ("segments") when intact—an immature proglottid, mature proglottid and a gravid proglottid. The average number of eggs per gravid proglottid is 823. Like all cyclophyllideans, ''E. granulosus'' has four suckers on its scolex ("head"), and ''E. granulosus'' also has a rostellum with hooks. Several strains of ''E. granulosus'' have been identified, and all but two are noted to be infective in humans. The lifecycle of ''E. granulosus'' involves dogs and wild carnivores as a definitive host for the adult tapeworm. Definitive hosts are where parasites reach maturity and reprodu ...
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Cestoda
Cestoda is a class of parasitic worms in the flatworm phylum (Platyhelminthes). Most of the species—and the best-known—are those in the subclass Eucestoda; they are ribbon-like worms as adults, known as tapeworms. Their bodies consist of many similar units known as proglottids—essentially packages of eggs which are regularly shed into the environment to infect other organisms. Species of the other subclass, Cestodaria, are mainly fish infecting parasites. All cestodes are parasitic; many have complex life histories, including a stage in a definitive (main) host in which the adults grow and reproduce, often for years, and one or two intermediate stages in which the larvae develop in other hosts. Typically the adults live in the digestive tracts of vertebrates, while the larvae often live in the bodies of other animals, either vertebrates or invertebrates. For example, '' Diphyllobothrium'' has at least two intermediate hosts, a crustacean and then one or more freshwater fi ...
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Dipylidium Caninum
''Dipylidium caninum,'' also called the flea tapeworm, double-pored tapeworm, or cucumber tapeworm (in reference to the shape of its cucumber-seed-like proglottids, though these also resemble grains of rice or sesame seeds), is a cyclophyllid cestode that infects organisms afflicted with fleas and canine chewing lice, including dogs, cats, and sometimes human pet-owners, especially children. Adult morphology The adult worm is about long. Gravid proglottids containing the worm's microscopic eggs are either passed in the definitive host's feces or may leave their host spontaneously and are then ingested by microscopic flea larvae (the intermediate hosts) in the surrounding environment. As in all members of family Dipylidiidae, proglottids of the adult worm have genital pores on both sides (hence the name ''double-pore tapeworm''). Each side has a set of male and female reproductive organs. The uterus is paired with 16 to 20 radial branches each. The scolex has a retractable ...
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Taenia Taeniaeformis
''Taenia taeniaeformis'' is a parasitic tapeworm, with cats as the primary definitive hosts. Sometime dogs can also be the definitive host. The intermediate hosts are rodents and less frequently lagomorphs (rabbits). The definitive host must ingest the liver of the intermediate host in order to acquire infection. The worm tends to be white, thick bodied, and around 15 to 60 cm in length. This species of tape worm is much less frequently encountered than ''Dipylidium caninum'', which has fleas as its intermediate host rather than rodents but exhibits most of the same physical characteristics and is treated with the same medications (i.e., antihelminthics). Lifecycle The eggs of the tapeworm are shed by the definitive host in the feces, and these are then consumed by rodents where they pass through several stages of development and cause various forms of damage, eventually coming to reside primarily in the liver and abdominal cavity where each scolex will create a fluid-fil ...
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Anthelmintics
Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. They may also be called vermifuges (those that stun) or vermicides (those that kill). Anthelmintics are used to treat people who are infected by helminths, a condition called helminthiasis. These drugs are also used to treat infected animals. Pills containing anthelmintics are used in mass deworming campaigns of school-aged children in many developing countries. The drugs of choice for soil-transmitted helminths are mebendazole and albendazole; for schistosomiasis and tapeworms it is praziquantel. Types Antiparasitics that specifically target worms of the genus ''Ascaris'' are called ascaricides. * Benzimidazoles: ** Albendazole – effective against threadworms, roundworms, whipworms, tapeworms, hookworms ** Mebendazole – effective against va ...
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Veterinary Drugs
An animal drug (also veterinary drug) refers to a drug intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in animals. Regulation United States The U.S. Food and Drug Administration (FDA) has the broad mandate under the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 321 et seq.) to assure the safety and effectiveness of animal drugs and their use in all animals, including farm animals. The division of the FDA responsible for this is the Center for Veterinary Medicine (CVM). The equivalents of the Investigational New Drug and New Drug Application are known as the Investigational New Animal Drug and New Animal Drug Application, respectively. Before CVM formally approves an animal drug, the sponsor or manufacturer of the drug must document in scientific testing that the drug has been found "safe and effective". The testing data also must demonstrate that a methodology is available to detect and measure any residue left in edible animal produ ...
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