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EpiBone
EpiBone is a biomedical engineering company that is developing technology to create bone tissue from a patient's mesenchymal stem cells ''in vitro'' for use in bone grafts. The company was founded by Nina Tandon Nina Marie Tandon is an American biomedical engineer. She is the CEO and co-founder of EpiBone. She currently serves as an adjunct professor of Electrical Engineering at Cooper Union and is a senior fellow at the Lab for Stem Cells and Tissue Eng ... and Sarindr “Ik” Bhumiratana. References {{Reflist Biomedical engineering Prosthetics ...
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Nina Tandon
Nina Marie Tandon is an American biomedical engineer. She is the CEO and co-founder of EpiBone. She currently serves as an adjunct professor of Electrical Engineering at Cooper Union and is a senior fellow at the Lab for Stem Cells and Tissue Engineering at Columbia. She was a 2011 TED Fellow and a 2012 senior TED Fellow. Personal life Nina Tandon grew up on Roosevelt Island in New York City. 0/sup> She had one brother and two sisters. 1/sup> As a child, Tandon discovered an interest in science when she discovered her siblings suffered from eye conditions. She and her siblings were each encouraged to try various science experiments; Tandon's siblings also pursued careers in scientific fields. 2/sup> As a child, she enjoyed "taking apart TVs and building these giant Tinkertoy towers, playing with static electricity, and experimenting on erclass for science fairs." 0/sup> She participated in puzzles and problem-solving, community theatre, poetry, and sewing. 3/sup> In addition ...
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Biomedical Engineering
Biomedical engineering (BME) or medical engineering is the application of engineering principles and design concepts to medicine and biology for healthcare purposes (e.g., diagnostic or therapeutic). BME is also traditionally logical sciences to advance health care treatment, including diagnosis, monitoring, and therapy. Also included under the scope of a biomedical engineer is the management of current medical equipment in hospitals while adhering to relevant industry standards. This involves procurement, routine testing, preventive maintenance, and making equipment recommendations, a role also known as a Biomedical Equipment Technician (BMET) or as clinical engineering. Biomedical engineering has recently emerged as its own study, as compared to many other engineering fields. Such an evolution is common as a new field transition from being an interdisciplinary specialization among already-established fields to being considered a field in itself. Much of the work in biomedica ...
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Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) also known as mesenchymal stromal cells or medicinal signaling cells are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells which give rise to marrow adipose tissue). Structure Definition While the terms ''mesenchymal stem cell'' (MSC) and ''marrow stromal cell'' have been used interchangeably for many years, neither term is sufficiently descriptive: * Mesenchyme is embryonic connective tissue that is derived from the mesoderm and that differentiates into hematopoietic and connective tissue, whereas MSCs do not differentiate into hematopoietic cells. * Stromal cells are connective tissue cells that form the supportive structure in which the functional cells of the tissue reside. While this is an accurate description for one function of MSCs, the term fails to convey the relatively recently discovered ...
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Bone Grafts
Bone grafting is a surgical procedure that replaces missing bone in order to repair bone fractures that are extremely complex, pose a significant health risk to the patient, or fail to heal properly. Some small or acute fractures can be cured without bone grafting, but the risk is greater for large fractures like compound fractures. Bone generally has the ability to regenerate completely but requires a very small fracture space or some sort of scaffold to do so. Bone grafts may be autologous (bone harvested from the patient's own body, often from the iliac crest), allograft (cadaveric bone usually obtained from a bone bank), or synthetic (often made of hydroxyapatite or other naturally occurring and biocompatible substances) with similar mechanical properties to bone. Most bone grafts are expected to be resorbed and replaced as the natural bone heals over a few months' time. The principles involved in successful bone grafts include osteoconduction (guiding the reparative growth ...
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Biomedical Engineering
Biomedical engineering (BME) or medical engineering is the application of engineering principles and design concepts to medicine and biology for healthcare purposes (e.g., diagnostic or therapeutic). BME is also traditionally logical sciences to advance health care treatment, including diagnosis, monitoring, and therapy. Also included under the scope of a biomedical engineer is the management of current medical equipment in hospitals while adhering to relevant industry standards. This involves procurement, routine testing, preventive maintenance, and making equipment recommendations, a role also known as a Biomedical Equipment Technician (BMET) or as clinical engineering. Biomedical engineering has recently emerged as its own study, as compared to many other engineering fields. Such an evolution is common as a new field transition from being an interdisciplinary specialization among already-established fields to being considered a field in itself. Much of the work in biomedica ...
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