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Enterotype
An enterotype is a classification of living organisms based on the bacteriological composition of their gut microbiota. The discovery of three human enterotypes was announced in the April 2011 issue of ''Nature'' by Peer Bork and his associates. They found that enterotypes are not dictated by age, gender, body weight, or national divisions. There are indications that long-term diet influences enterotype. Type 1 is characterized by high levels of ''Bacteroides'', type 2 has few ''Bacteroides'' but ''Prevotella'' are common, and type 3 has high levels of '' Ruminococcus''. The value of classifying by enterotype has been challenged. In a study of gut bacteria of children in Burkina Faso (in Africa), ''Prevotella'' made up 53% of the gut bacteria, but were absent in age-matched European children. Studies also indicate that long-term diet is strongly associated with the gut microbiome composition—those who eat plenty of protein and animal fats typical of Western diet have predominan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gut Flora
Gut microbiota, gut microbiome, or gut flora, are the microorganisms, including bacteria, archaea, fungi, and viruses that live in the digestive tracts of animals. The gastrointestinal metagenome is the aggregate of all the genomes of the gut microbiota. The gut is the main location of the human microbiome. The gut microbiota has broad impacts, including effects on colonization, resistance to pathogens, maintaining the intestinal epithelium, metabolizing dietary and pharmaceutical compounds, controlling immune function, and even behavior through the gut–brain axis. The microbial composition of the gut microbiota varies across regions of the digestive tract. The colon contains the highest microbial density recorded in any habitat on Earth, representing between 300 and 1000 different species. Bacteria are the largest and to date, best studied component and 99% of gut bacteria come from about 30 or 40 species. Up to 60% of the dry mass of feces is bacteria. Over 99% of the bac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gut Microbiome
Gut microbiota, gut microbiome, or gut flora, are the microorganisms, including bacteria, archaea, fungi, and viruses that live in the digestive tracts of animals. The gastrointestinal metagenome is the aggregate of all the genomes of the gut microbiota. The gut is the main location of the human microbiome. The gut microbiota has broad impacts, including effects on colonization, resistance to pathogens, maintaining the intestinal epithelium, metabolizing dietary and pharmaceutical compounds, controlling immune function, and even behavior through the gut–brain axis. The microbial composition of the gut microbiota varies across regions of the digestive tract. The colon contains the highest microbial density recorded in any habitat on Earth, representing between 300 and 1000 different species. Bacteria are the largest and to date, best studied component and 99% of gut bacteria come from about 30 or 40 species. Up to 60% of the dry mass of feces is bacteria. Over 99% of the bacter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacteroides
''Bacteroides'' is a genus of Gram-negative, obligate anaerobic bacteria. ''Bacteroides'' species are non endospore-forming bacilli, and may be either motile or nonmotile, depending on the species. The DNA base composition is 40–48% GC. Unusual in bacterial organisms, ''Bacteroides'' membranes contain sphingolipids. They also contain meso-diaminopimelic acid in their peptidoglycan layer. ''Bacteroides'' species are normally mutualistic, making up the most substantial portion of the mammalian gastrointestinal microbiota, where they play a fundamental role in processing of complex molecules to simpler ones in the host intestine. As many as 1010–1011 cells per gram of human feces have been reported. They can use simple sugars when available; however, the main sources of energy for ''Bacteroides'' species in the gut are complex host-derived and plant glycans. Studies indicate that long-term diet is strongly associated with the gut microbiome composition—those who eat plenty ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prevotella
''Prevotella'' is a genus of Gram-negative bacteria. ''Prevotella'' spp. are members of the oral, vaginal, and gut microbiota and are often recovered from anaerobic infections of the respiratory tract. These infections include aspiration pneumonia, lung abscess, pulmonary empyema, and chronic otitis media and sinusitis. They have been isolated from abscesses and burns in the vicinity of the mouth, bites, paronychia, urinary tract infection, brain abscesses, osteomyelitis, and bacteremia associated with upper respiratory tract infections. ''Prevotella'' spp. predominate in periodontal disease and periodontal abscesses. Role in gut microbiota Human gut is mainly inhabited by two phyla of bacteria—''Bacillota'' and ''Bacteroidota'', the latter mostly dominated by ''Bacteroides'' and ''Prevotella'' genera. ''Prevotella'' and ''Bacteroides'' are thought to have had a common ancestor. Formally, the two genera were differentiated in 1990. However classification is still undergoin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 ''Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in exp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peer Bork
Peer Bork (born 4 May 1963) is a German bioinformatician. He is Director of the European Molecular Biology Laboratory (EMBL) site in Heidelberg, in south-west Germany. Bork received his PhD in biochemistry in 1990 from the Leipzig University and his habilitation in theoretical biophysics in 1995 from the Humboldt University of Berlin. He was appointed a Group Leader at EMBL in 1995. He has worked on the microbiomes of humans and other animals. He is on the board of editorial reviewers of ''Science'', and is a senior editor of the journal ''Molecular Systems Biology''. In 2000 Bork was elected as a Member of the European Molecular Biology Organization, and in 2008 he received the ''Nature'' "mid-career achievement" award for science mentoring in Germany. He was appointed a member of the German National Academy of Sciences Leopoldina in 2014. He received an honorary doctorate from the University of Würzburg in 2014 and the University of Utrecht in 2017. In 2021, Bork was aw ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ruminococcus
''Ruminococcus'' is a genus of bacteria in the class Clostridia. They are anaerobic, Gram-positive gut microbes. One or more species in this genus are found in significant numbers in the human gut microbiota. The type species is ''R. flavefaciens''. As usual, bacteria taxonomy is in flux, with Clostridia being paraphyletic, and some erroneous members of ''Ruminococcus'' being reassigned to a new genus ''Blautia'' on the basis of 16S rRNA gene sequences. One of the most highly cited papers involving the genus ''Ruminococcus'' is a paper describing interspecies hydrogen transfer between ''Ruminococcus albus'' and ''Wolinella succinogenes''. In 1972, ''Ruminococcus bromii'' was reportedly found in the human gut, which was the first of several species discovered. They may play a role in plant cell wall breakdown in the colon. One study found that ''R. albus'', ''R. callidus'', and ''R. bromii'' are less abundant in people with inflammatory bowel disease. ''Ruminococcus'' are als ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Burkina Faso
Burkina Faso (, ; , ff, 𞤄𞤵𞤪𞤳𞤭𞤲𞤢 𞤊𞤢𞤧𞤮, italic=no) is a landlocked country in West Africa with an area of , bordered by Mali to the northwest, Niger to the northeast, Benin to the southeast, Togo and Ghana to the south, and the Ivory Coast to the southwest. It has a population of 20,321,378. Previously called Republic of Upper Volta (1958–1984), it was renamed Burkina Faso by President Thomas Sankara. Its citizens are known as ''Burkinabè'' ( ), and its capital and largest city is Ouagadougou. The largest ethnic group in Burkina Faso is the Mossi people, who settled the area in the 11th and 13th centuries. They established powerful kingdoms such as the Ouagadougou, Tenkodogo, and Yatenga. In 1896, it was colonized by the French as part of French West Africa; in 1958, Upper Volta became a self-governing colony within the French Community. In 1960, it gained full independence with Maurice Yaméogo as president. Throughout the decades post in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Common Chimpanzee
The chimpanzee (''Pan troglodytes''), also known as simply the chimp, is a species of Hominidae, great ape native to the forest and savannah of tropical Africa. It has four confirmed subspecies and a fifth proposed subspecies. When its close relative the bonobo was more commonly known as the pygmy chimpanzee, this species was often called the common chimpanzee or the robust chimpanzee. The chimpanzee and the bonobo are the only species in the genus Pan (genus), ''Pan''. Evidence from fossils and DNA sequencing shows that ''Pan'' is a sister taxon to the Human evolution, human lineage and is humans' closest living relative. The chimpanzee is covered in coarse black hair, but has a bare face, fingers, toes, palms of the hands, and soles of the feet. It is larger and more Robustness (morphology), robust than the bonobo, weighing for males and for females and standing . The chimpanzee lives in groups that range in size from 15 to 150 members, although individuals travel and forag ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacteriology
Bacteriology is the branch and specialty of biology that studies the morphology, ecology, genetics and biochemistry of bacteria as well as many other aspects related to them. This subdivision of microbiology involves the identification, classification, and characterization of bacterial species. Because of the similarity of thinking and working with microorganisms other than bacteria, such as protozoa, fungi, and viruses, there has been a tendency for the field of bacteriology to extend as microbiology. The terms were formerly often used interchangeably. However, bacteriology can be classified as a distinct science. Overview Definition Bacteriology is the study of bacteria and their relation to medicine. Bacteriology evolved from physicians needing to apply the germ theory to address the concerns relating to disease spreading in hospitals the 19th century. Identification and characterizing of bacteria being associated to diseases led to advances in pathogenic bacteriology. K ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
