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Endoflagella Components
A spirochaete () American and British English spelling differences#ae and oe, or spirochete is a member of the phylum (biology), phylum Spirochaetota (), (synonym Spirochaetes) which contains distinctive diderm bacteria, diderm (double-membrane) gram-negative bacteria, most of which have long, spiral bacteria, helically coiled (corkscrew-shaped or spiraled, hence the name) cells. Spirochaetes are chemoheterotrophic in nature, with lengths between 3 and 500 μm and diameters around 0.09 to at least 3 μm. Spirochaetes are distinguished from other bacterial phyla by the location of their flagellum, flagella, called endoflagella which are sometimes called ''axial filaments''. Endoflagella are anchored at each end (pole) of the bacterium within the periplasmic space (between the inner and outer membranes) where they project backwards to extend the length of the cell. These cause a twisting motion which allows the spirochaete to move about. When reproducing, a spirochae ...
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Treponema Pallidum
''Treponema pallidum'', formerly known as ''Spirochaeta pallida'', is a spirochaete bacterium with various subspecies that cause the diseases syphilis, bejel (also known as endemic syphilis), and yaws. It is transmitted only among humans. It is a helically coiled microorganism usually 6–15 μm long and 0.1–0.2 μm wide. ''T. pallidum'''s lack of either a tricarboxylic acid cycle or oxidative phosphorylation results in minimal metabolic activity. The treponemes have a cytoplasmic and an outer membrane. Using light microscopy, treponemes are visible only by using dark field illumination. ''Treponema pallidum'' consists of three subspecies, ''T. p. pallidum, T. p. endemicum,'' and ''T. p. pertenue,'' each of which has a distinct associated disease. Subspecies Three subspecies of ''T. pallidum'' are known: * ''Treponema pallidum pallidum'', which causes syphilis * ''T. p. endemicum'', which causes bejel or endemic syphilis * ''T. p. pertenue'', which causes yaws The ...
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Periplasmic Space
The periplasm is a concentrated gel-like matrix in the space between the inner cytoplasmic membrane and the bacterial outer membrane called the ''periplasmic space'' in gram-negative bacteria. Using cryo-electron microscopy it has been found that a much smaller periplasmic space is also present in gram-positive bacteria., Matias, V. R., and T. J. Beveridge. 2005. Cryo-electron microscopy reveals native polymeric cell wall structure in Bacillus subtilis 168 and the existence of a periplasmic space. Mol. Microbiol. 56:240-251. ., Zuber B, Haenni M, Ribeiro T, Minnig K, Lopes F, Moreillon P, Dubochet J. 2006. Granular layer in the periplasmic space of Gram-positive bacteria and fine structures of Enterococcus gallinarum and Streptococcus gordonii septa revealed by cryo-electron microscopy of vitreous sections. J Bacteriol. 188:6652-6660. The periplasm may constitute up to 40% of the total cell volume of gram-negative bacteria, but is a much smaller percentage in gram-positive bacter ...
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Borrelia Recurrentis
''Borrelia recurrentis'' is a species of ''Borrelia'', a spirochaete bacterium associated with relapsing fever. ''B. recurrentis'' is usually transmitted from person to person by the human body louse The body louse (''Pediculus humanus humanus'', also known as ''Pediculus humanus corporis'') is a hematophagic ectoparasite louse that infests humans. It is one of three lice which infest humans, the other two being the head louse, and the c .... Since the 1800s, the body louse has been known as its only known vector. ''B. recurrentis'' DNA was found in 23% of head lice from patients with louse-borne relapsing fever in Ethiopia. Whether head lice can transmit these bacteria from one person to another remains to be determined. It is notable for its ability to alter the proteins expressed on its surface, which causes the "relapsing" characteristic of relapsing fever. References recurrentis {{spirochaetes-stub ...
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Borrelia Lusitaniae
''Borrelia lusitaniae'' is a bacterium of the spirochete class of the genus'' Borrelia'', which has a diderm (double-membrane) envelope. It is a part of the ''Borrelia burgdorferi'' ''sensu lato'' genospecies and is a Gram-negative bacterium. ''B. lusitaniae'' is tick-borne; he type strain is PotiB2. It can be pathogenic, being involved in cases of Lyme borreliosis. A species of tick, ''Ixodes ricinus'', is the host of ''B. lusitaniae''. It is thought to have originated from Portugal and has since spread to parts of Europe and North Africa. Lizards of the family Lacertidae are now believed to be important reservoir hosts of this bacterium. Origin and distribution While ''B. lusitaniae'' is distributed throughout countries in Europe and North Africa, it is the sole species of the Lyme borreliosis group in southern Portugal. Lizards of the family Lacertidae are believed to be important reservoir hosts of ''B. lusitaniae''. They were first isolated in Portugal in 1993. These lizar ...
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Borrelia Spielmanii
''Borrelia spielmanii'' is a spirochete bacterium; it routinely infects ''Ixodes ricinus'', and subsequently humans, causing Lyme disease Lyme disease, also known as Lyme borreliosis, is a vector-borne disease caused by the ''Borrelia'' bacterium, which is spread by ticks in the genus ''Ixodes''. The most common sign of infection is an expanding red rash, known as erythema migran ....Földvári, Gábor, Róbert Farkas, and András Lakos. "Borrelia spielmanii erythema migrans, Hungary." Emerging infectious diseases 11.11 (2005): 1794. References Further reading * * * External linksNCBI Taxonomy Browser - Borrelia* spielmanii Bacteria described in 2006 {{Spirochaetae-stub ...
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Borrelia Afzelii
''Borrelia afzelii'' is a species of ''Borrelia'' a bacterium that can infect various species of vertebrates and invertebrates. Among 30 ''Borrelia'' known species, it is one of four which are likely to infect humans causing a variant of Lyme disease. Coinfection by this ''Borrelia'' species with one or more pathogens can occur, carried by the vector, which appears to be in most cases the tick. It is named after Swedish dermatologist Arvid Afzelius. See also * Lyme disease Lyme disease, also known as Lyme borreliosis, is a vector-borne disease caused by the ''Borrelia'' bacterium, which is spread by ticks in the genus ''Ixodes''. The most common sign of infection is an expanding red rash, known as erythema migran ... References Further reading * External links Type strain of ''Borrelia afzelii'' at Bac''Dive'' - the Bacterial Diversity Metadatabase Lyme disease afzelii Bacteria described in 1994 {{Spirochaetae-stub ...
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Borrelia Garinii
''Borrelia garinii'' is a spirochete bacterium in the genus ''Borrelia ''Borrelia'' is a genus of bacteria of the spirochete phylum. Several species cause Lyme disease, also called Lyme borreliosis, a zoonotic, vector-borne disease transmitted by ticks. Other species of ''Borrelia'' cause relapsing fever, and are tr ...''. References Further reading * External links NCBI Taxonomy Browser - BorreliaBorrelia burgdoferi B31 Genome PageBorrelia Garinii PBi Genome Page
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Borrelia Bissettii
''Borrelia bissettiae'' (formerly B. bissettii, before renaming in 2019) is a spirochete bacterium. The type strain is strain DN127. It is pathogenic and causes Lyme borreliosis in the Americas and Eurasia. See also *Lyme disease microbiology Lyme disease, or borreliosis, is caused by spirochetal bacteria from the genus '' Borrelia'', which has 52 known species. Three main species (''Borrelia garinii'', ''Borrelia afzelii'', and ''Borrelia burgdorferi s.s.'') are the main causative ag ... References Further reading * * External links NCBI Taxonomy Browser - Borrelia*Type strain of ''Borrelia bissettii'' at Bac''Dive'' - the Bacterial Diversity Metadatabase bissettii Bacteria described in 1998 {{Spirochaetae-stub ...
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Borrelia Mayonii
''Borrelia mayonii'' is a Gram-negative, host-associated spirochete that is capable of causing Lyme disease. This organism can infect various vertebrate and invertebrate hosts such as humans and ticks, primarily ''Ixodes scapularis''. Migratory songbirds play a role in the dispersal of the tick vector, ''Ixodes scapularis'', across long distances, indirectly dispersing ''Borrelia mayonii'' as well. Phylogenetic information ''Borrelia mayonii'' was identified as a ''sensu lato'' (broad sense), genospecies (Bbsl) of the known microbe, ''Borrelia burgdorferi''. A genospecies is a cluster of organisms with similar core genes that usually does not undergo genetic recombination with diverged organisms.  Two isolates, gene strains, of ''B. mayonii'', named MN14-1420 and MN14-1539, were sequenced, process of arranging a chain of genetic information to match up to a specific organism's genetic code, and compared to the genome or genetic material of ''Borrelia burgdorferi''. With a n ...
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Borrelia Burgdorferi
''Borrelia burgdorferi'' is a bacterial species of the spirochete class in the genus ''Borrelia'', and is one of the causative agents of Lyme disease in humans. Along with a few similar genospecies, some of which also cause Lyme disease, it makes up the species complex of ''Borrelia burgdorferi'' sensu lato. The complex currently comprises 20 accepted and 3 proposed genospecies. ''B. burgdorferi'' sensu stricto exists in North America and Eurasia and until 2016 was the only known cause of Lyme disease in North America. ''Borrelia'' species are Gram-negative. Microbiology ''Borrelia burgdorferi'' is named after the researcher Willy Burgdorfer, who first isolated the bacterium in 1982. ''Borrelia burgdorferi'' is a microaerophile, requiring small amounts of oxygen in order to undergo glycolysis and survive. Like all other ''Borrelia'' sps., this bacterium is also gram-negative and a spirochete. Borrelia colonies are often smaller, rounded, and white with an elevated center. ''B. b ...
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Leptospirosis
Leptospirosis is a blood infection caused by the bacteria ''Leptospira''. Signs and symptoms can range from none to mild (headaches, muscle pains, and fevers) to severe ( bleeding in the lungs or meningitis). Weil's disease, the acute, severe form of leptospirosis, causes the infected individual to become jaundiced (skin and eyes become yellow), develop kidney failure, and bleed. Bleeding from the lungs associated with leptospirosis is known as severe pulmonary haemorrhage syndrome. More than ten genetic types of ''Leptospira'' cause disease in humans. Both wild and domestic animals can spread the disease, most commonly rodents. The bacteria are spread to humans through animal urine, or water and soil contaminated with animal urine, coming into contact with the eyes, mouth, nose or breaks in the skin. In developing countries, the disease occurs most commonly in farmers and low-income people who live in areas with poor sanitation. In developed countries, it occurs during heavy ...
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Leptospira
''Leptospira'' ( grc, leptos, italics=yes, 'fine, thin' and la, spira, links=no, 'coil') is a genus of spirochaete bacteria, including a small number of pathogenic and saprophytic species. ''Leptospira'' was first observed in 1907 in kidney tissue slices of a leptospirosis victim who was described as having died of "yellow fever". Taxonomy ''Leptospira'', together with the genera ''Leptonema'' and ''Turneria'', is a member of the family Leptospiraceae. The genus ''Leptospira'' is divided into 20 species based on DNA hybridization studies. Pathogenic ''Leptospira'' :''Leptospira alstonii'' Smythe et al. 2013 ''Leptospira alstoni''" Haake et al. 1993:''Leptospira interrogans'' (Stimson 1907) Wenyon 1926 emend. Faine and Stallman 1982 ["''Spirochaeta interrogans''" Stimson 1907; "''Spirochaeta nodosa''" Hubener & Reiter 1916; "''Spirochaeta icterohaemorrhagiae''" Inada et al. 1916; "''Spirochaeta icterogenes''" Uhlenhuth & Fromme 1916; "''Leptospira icteroides''" Noguchi 1919 ...
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