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Emmanuel Farber
Emmanuel Farber (October 19, 1918, Toronto, Canada – August 3, 2014, Columbia, South Carolina) was a Canadian-American physician, pathologist, biochemist, and oncologist. He is known for his research on the biochemistry of carcinogenesis. Biography His parents emigrated from Russia to Canada and the United States. His sister Sophie became a concert pianist and his brother Lionel earned a Ph.D. at the University of Toronto and became a professor of biochemistry at the University of California, San Francisco. Emmanuel Farber graduated in 1942 with an M.D. from the University of Toronto Faculty of Medicine. In April 1942 he married Ruth Wilma Diamond. From 1942 to 1946 he served as a captain in the Royal Canadian Army Medical Corps. From 1942 to 1943 he did his medical internship and medical residency in pathology at Hamilton General Hospital. Supported from 1947 to 1949 by a fellowship in cancer research from the American Cancer Society, he became a graduate student in biochemistry ...
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Farber Disease
Farber disease (also known as Farber's lipogranulomatosis, acid ceramidase deficiency, "Lipogranulomatosis", and ''ASAH1''-related disorders) is an extremely rare, progressive, autosomal recessive lysosomal storage disease caused by a deficiency of the acid ceramidase enzyme. Acid ceramidase is responsible for breaking down ceramide into sphingosine and fatty acid. When the enzyme is deficient, this leads to an accumulation of fatty material (called ceramide) in the lysosomes of the cells, leading to the signs and symptoms of this disorder. Signs and Symptoms The symptoms of Farber disease develop over time. The onset of symptoms and how quickly they progress vary from person to person. The most common symptoms include: * Bumps under the skin located at pressure points and joints, also called subcutaneous nodules, lipogranulomas, or granulomas * Swollen, painful joints with progressive limitation of range of motion resulting in contracture * Hoarse voice/cry Other symptoms obs ...
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The American Journal Of Pathology
''The American Journal of Pathology'' is a monthly peer-reviewed medical journal covering pathology. It is published by Elsevier on behalf of the American Society for Investigative Pathology, of which it is an official journal. The editor-in-chief is Martha B. Furie ( Stony Brook University). The journal was established in 1896 as the ''Journal of the Boston Society of Medical Sciences'' and renamed ''The Journal of Medical Research'' in 1901, before obtaining its current title in 1925. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 4.307. Editors The following persons have been editors-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The highest-ranking editor of a publication may also be titled editor, managing ... of the journal: References External links * {{DEFAULTSORT:American Journal Of Pathology, ...
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Royal Society Of Canada
The Royal Society of Canada (RSC; french: Société royale du Canada, SRC), also known as the Academies of Arts, Humanities and Sciences of Canada (French: ''Académies des arts, des lettres et des sciences du Canada''), is the senior national, bilingual council of distinguished Canadian scholars, humanists, scientists and artists. The primary objective of the RSC is to promote learning and research in the arts, the humanities and the sciences. The RSC is Canada's National Academy and exists to promote Canadian research and scholarly accomplishment in both official languages, to recognize academic and artistic excellence, and to advise governments, non-governmental organizations and Canadians on matters of public interest. History In the late 1870s, the Governor General of Canada, the Marquis of Lorne, determined that Canada required a cultural institution to promote national scientific research and development. Since that time, succeeding Governor Generals have remained involved w ...
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American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal of ...
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Legacy
In law, a legacy is something held and transferred to someone as their inheritance, as by will and testament. Personal effects, family property, marriage property or collective property gained by will of real property. Legacy or legacies may refer to: Arts, media and entertainment People * “Legacy”, a.k.a. Big Popp, a legend in Natick M.A. Comics * " Batman: Legacy", a 1996 Batman storyline * '' DC Universe: Legacies'', a comic book series from DC Comics written by Len Wein * ''Legacy'', a 1999 quarterly series from Antarctic Press * ''Legacy'', a 2003–2005 series released by Dabel Brothers Productions * Legacy, an alternate name for the DC supervillain Wizard who leads the Injustice Society IV team * Legacy (Marvel Comics), an alias used by Genis-Vell, better known as Captain Marvel * Legacy Virus, a fictional virus from the Marvel Universe * Marvel Legacy, a comic book line introduced in 2017 * '' Star Wars: Legacy'', a 2006 series from Dark Horse * '' X-Men: Legacy ...
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Adduct
An adduct (from the Latin ''adductus'', "drawn toward" alternatively, a contraction of "addition product") is a product of a direct addition of two or more distinct molecules, resulting in a single reaction product containing all atoms of all components. The resultant is considered a distinct molecular species. Examples include the addition of sodium bisulfite to an aldehyde to give a sulfonate. It can just be considered as a single product resulting from the direct combination of different molecules which comprises all the reactant molecules' atoms. Adducts often form between Lewis acids and Lewis bases. A good example is the formation of adducts between the Lewis acid borane and the oxygen atom in the Lewis bases, tetrahydrofuran (THF): BH3·O(CH2)4 or diethyl ether: BH3·O(CH3CH2)2. Many Lewis acids and Lewis bases reacting in the gas phase or in non-aqueous solvents to form adducts have been examined in the ECW model. Trimethylboron, trimethyltin chloride and bis(hexaflu ...
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Passive Smoking
Passive smoking is the inhalation of tobacco smoke, called secondhand smoke (SHS), or environmental tobacco smoke (ETS), by persons other than the intended "active" smoker. It occurs when tobacco smoke enters an environment, causing its inhalation by people within that environment. Exposure to secondhand tobacco smoke causes disease, disability, and death. The health risks of secondhand smoke are a matter of scientific consensus. These risks have been a major motivation for smoke-free laws in workplaces and indoor public places, including restaurants, bars and night clubs, as well as some open public spaces. Concerns around secondhand smoke have played a central role in the debate over the harms and regulation of tobacco products. Since the early 1970s, the tobacco industry has viewed public concern over secondhand smoke as a serious threat to its business interests. Harm to bystanders was perceived as a motivator for stricter regulation of tobacco products. Despite the indust ...
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Tobacco Smoking
Tobacco smoking is the practice of burning tobacco and ingesting the resulting smoke. The smoke may be inhaled, as is done with cigarettes, or simply released from the mouth, as is generally done with pipes and cigars. The practice is believed to have begun as early as 5000–3000 BC in Mesoamerica and South America. Tobacco was introduced to Eurasia in the late 17th century by European colonists, where it followed common trade routes. The practice encountered criticism from its first import into the Western world onwards but embedded itself in certain strata of a number of societies before becoming widespread upon the introduction of automated cigarette-rolling apparatus. Smoking is the most common method of consuming tobacco, and tobacco is the most common substance smoked. The agricultural product is often mixed with additives and then combusted. The resulting smoke is then inhaled and the active substances absorbed through the alveoli in the lungs or the oral mucosa. Many ...
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Report Of The Advisory Committee To The Surgeon General Of The United States
A report is a document that presents information in an organized format for a specific audience and purpose. Although summaries of reports may be delivered orally, complete reports are almost always in the form of written documents. Usage In modern business scenario, reports play a major role in the progress of business. Reports are the backbone to the thinking process of the establishment and they are responsible, to a great extent, in evolving an efficient or inefficient work environment. The significance of the reports includes: * Reports present adequate information on various aspects of the business. * All the skills and the knowledge of the professionals are communicated through reports. * Reports help the top line in decision making. * A rule and balanced report also helps in problem solving. * Reports communicate the planning, policies and other matters regarding an organization to the masses. News reports play the role of ombudsman and levy checks and balances on th ...
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Chemico-Biological Interactions
''Chemico-Biological Interactions'' is a peer-reviewed scientific journal covering toxicological Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms and the practice of diagnosing and treating expos ... aspects of interactions between chemicals and biological systems. External links * Publications established in 1969 Elsevier academic journals Toxicology journals English-language journals {{sci-journal-stub ...
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Hepatology (journal)
''Hepatology'' is a peer-reviewed medical journal of hepatology. It is published monthly by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases. The journal was established in 1981 and the editor-in-chief is David E Cohen ( Weill Cornell Medical). Indexing and abstracting The journal is abstracted and indexed in the following databases: According to ''Journal Citation Reports'', the journal's 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... is 17.425, ranking it 6th out of 92 journals in the category "Gastroenterology & Hepatology". References External links *{{Official website, http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1527-3350American Association for the Study of Liver Diseases Gastroenterology and hepa ...
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International Journal Of Cancer
The ''International Journal of Cancer'' is a biweekly peer-reviewed medical journal covering experimental and clinical cancer research. It publishes original research articles, mini reviews, short reports, and letters to the editor. The journal was established in 1966 and is published by John Wiley & Sons on behalf of the Union for International Cancer Control. The editor-in-chief is Christoph Plass (Deutsches Krebsforschungszentrum). According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 7.396. References External links

*{{Official website, https://onlinelibrary.wiley.com/journal/10970215 Oncology journals Publications established in 1966 English-language journals Wiley (publisher) academic journals Biweekly journals ...
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