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Els Goulmy
Els Goulmy (born 27 November 1946, The Hague) is an eminent professor of transplantation biology, especially regarding minor histocompatibility antigen, at Leiden University. Goulmy is an expert in the area of tissue typing and belongs internationally to the absolute top of her discipline. She was awarded the Spinoza Prize in 2002. Research Goulmy did groundbreaking research on the role of antigens in organ and stem cell transplantation. She is the pioneer of the so-called Minor Transplantation Antigens in men. Minor antigens can induce strong immune reactions. She discovered the H-Y minor antigen encoded by the Y-chromosome (1976) and the autosomally encoded HA-1 antigen (1983). She then described the polymorphism and the population frequencies of several autosomal minor antigens. Crucial was her work on the differential expression of minor antigens showing either overall expression on all body cells, such as the male specific H-Y antigens, or restricted expression on solely bloo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Hague
The Hague ( ; nl, Den Haag or ) is a city and municipality of the Netherlands, situated on the west coast facing the North Sea. The Hague is the country's administrative centre and its seat of government, and while the official capital of the Netherlands is Amsterdam, The Hague has been described as the country's de facto capital. The Hague is also the capital of the province of South Holland, and the city hosts both the International Court of Justice and the International Criminal Court. With a population of over half a million, it is the third-largest city in the Netherlands, after Amsterdam and Rotterdam. The Hague is the core municipality of the Greater The Hague urban area, which comprises the city itself and its suburban municipalities, containing over 800,000 people, making it the third-largest urban area in the Netherlands, again after the urban areas of Amsterdam and Rotterdam. The Rotterdam–The Hague metropolitan area, with a population of approximately 2.6&n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Minor Histocompatibility Antigen
Minor histocompatibility antigen (also known as MiHA) are receptors on the cellular surface of donated organs that are known to give an immunological response in some organ transplants. They cause problems of rejection less frequently than those of the major histocompatibility complex (MHC). Minor histocompatibility antigens (MiHAs) are diverse, short segments of proteins and are referred to as peptides . These peptides are normally around 9-12 amino acids in length and are bound to both the major histocompatibility complex (MHC) class I and class II proteins. Peptide sequences can differ among individuals and these differences arise from SNPs in the coding region of genes, gene deletions, frameshift mutations, or insertions. About a third of the characterized MiHAs come from the Y chromosome. The proteins are composed of a single immunogenic HLA allele . Prior to becoming a short peptide sequence, the proteins expressed by these polymorphic or diverse genes need to be digested ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leiden University
Leiden University (abbreviated as ''LEI''; nl, Universiteit Leiden) is a Public university, public research university in Leiden, Netherlands. The university was founded as a Protestant university in 1575 by William the Silent, William, Prince of Orange, as a reward to the city of Leiden for its Siege of Leiden, defence against Spanish attacks during the Eighty Years' War. As the oldest institution of higher education in the Netherlands, it enjoys a reputation across Europe and the world. Known for its historic foundations and emphasis on the social sciences, the university came into particular prominence during the Dutch Golden Age, when scholars from around Europe were attracted to the Dutch Republic due to its climate of intellectual tolerance and Leiden's international reputation. During this time, Leiden became the home to individuals such as René Descartes, Rembrandt, Christiaan Huygens, Hugo Grotius, Baruch Spinoza and Baron d'Holbach. The university has seven academic f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spinoza Prize
The Spinoza Prize ( nl, Spinozapremie) is an annual award of 2.5 million euro, to be spent on new research given by the Dutch Research Council (NWO). The award is the highest scientific award in the Netherlands. It is named after the philosopher Baruch de Spinoza Baruch (de) Spinoza (born Bento de Espinosa; later as an author and a correspondent ''Benedictus de Spinoza'', anglicized to ''Benedict de Spinoza''; 24 November 1632 – 21 February 1677) was a Dutch philosopher of Portuguese-Jewish origin, b .... The prize is awarded to researchers in the Netherlands who belong to the best in their field. Academics can nominate each other and an international commission evaluates the submissions. It is sometimes referred to as the Dutch Nobel Prize. List of winners The following persons have received the Spinoza Prize: References External links * {{Official website, http://www.nwo.nl/en/research-and-results/programmes/spinoza+prize, name = Spinoza Prize Awards establis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stanford University School Of Medicine
Stanford University School of Medicine is the medical school of Stanford University and is located in Stanford, California. It traces its roots to the Medical Department of the University of the Pacific, founded in San Francisco in 1858. This medical institution, then called Cooper Medical College, was acquired by Stanford in 1908. The medical school moved to the Stanford campus near Palo Alto, California, in 1959. The School of Medicine, along with Stanford Health Care and Lucile Packard Children's Hospital, is part of Stanford Medicine. Stanford Health Care was ranked the fourth best hospital in California (behind UCLA Medical Center, Cedars-Sinai Medical Center, and UCSF Medical Center, respectively). History In 1855, Illinois physician Elias Samuel Cooper moved to San Francisco in the wake of the California Gold Rush. In cooperation with the University of the Pacific (also known as California Wesleyan College), Cooper established the Medical Department of the Univers ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1946 Births
Events January * January 6 - The 1946 North Vietnamese parliamentary election, first general election ever in Vietnam is held. * January 7 – The Allies recognize the Austrian republic with its 1937 borders, and divide the country into four Allied-occupied Austria, occupation zones. * January 10 ** The first meeting of the United Nations is held, at Methodist Central Hall Westminster in London. ** ''Project Diana'' bounces radar waves off the Moon, measuring the exact distance between the Earth and the Moon, and proves that communication is possible between Earth and outer space, effectively opening the Space Age. * January 11 - Enver Hoxha declares the People's Republic of Albania, with himself as prime minister of Albania, prime minister. * January 16 – Charles de Gaulle resigns as head of the Provisional Government of the French Republic, French provisional government. * January 17 - The United Nations Security Council holds its first session, at Church House, Westmin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science Teachers
Science is a systematic endeavor that builds and organizes knowledge in the form of testable explanations and predictions about the universe. Science may be as old as the human species, and some of the earliest archeological evidence for scientific reasoning is tens of thousands of years old. The earliest written records in the history of science come from Ancient Egypt and Mesopotamia in around 3000 to 1200 BCE. Their contributions to mathematics, astronomy, and medicine entered and shaped Greek natural philosophy of classical antiquity, whereby formal attempts were made to provide explanations of events in the physical world based on natural causes. After the fall of the Western Roman Empire, knowledge of Greek conceptions of the world deteriorated in Western Europe during the early centuries (400 to 1000 CE) of the Middle Ages, but was preserved in the Muslim world during the Islamic Golden Age and later by the efforts of Byzantine Greek scholars who brought Greek man ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spinoza Prize Winners
Baruch (de) Spinoza (born Bento de Espinosa; later as an author and a correspondent ''Benedictus de Spinoza'', anglicized to ''Benedict de Spinoza''; 24 November 1632 – 21 February 1677) was a Dutch philosopher of Portuguese-Jewish origin, born in Amsterdam. One of the foremost exponents of 17th-century Rationalism and one of the early and seminal thinkers of the Enlightenment and modern biblical criticism including modern conceptions of the self and the universe, he came to be considered "one of the most important philosophers—and certainly the most radical—of the early modern period." Inspired by Stoicism, Jewish Rationalism, Machiavelli, Hobbes, Descartes, and a variety of heterodox religious thinkers of his day, Spinoza became a leading philosophical figure during the Dutch Golden Age. Spinoza's given name, which means "Blessed", varies among different languages. In Hebrew, his full name is written . In most of the documents and records contemporary with Spinoza's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academic Staff Of Leiden University
An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulation, dev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
