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Eijkman
Christiaan Eijkman ( , , ; 11 August 1858 – 5 November 1930) was a Dutch physician and professor of physiology whose demonstration that beriberi is caused by poor diet led to the discovery of antineuritic vitamins (thiamine). Together with Sir Frederick Hopkins, he received the Nobel Prize for Physiology or Medicine in 1929 for the discovery of vitamins. Biography Early life and education Christiaan Eijkman was born on 11 August 1858, at Nijkerk, Netherlands as the seventh child of Christiaan Eijkman, the headmaster of a local school, and Johanna Alida Pool. His elder brother Johann Frederik Eijkman (1851–1915) was also a chemist. A year later, in 1859, the Eijkman family moved to Zaandam, where his father was appointed head of a newly founded school for advanced elementary education. It was here that Christiaan and his brothers received their early education. In 1875, after taking his preliminary examinations, Eijkman became a student at the Military Medical School of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eijkman
Christiaan Eijkman ( , , ; 11 August 1858 – 5 November 1930) was a Dutch physician and professor of physiology whose demonstration that beriberi is caused by poor diet led to the discovery of antineuritic vitamins (thiamine). Together with Sir Frederick Hopkins, he received the Nobel Prize for Physiology or Medicine in 1929 for the discovery of vitamins. Biography Early life and education Christiaan Eijkman was born on 11 August 1858, at Nijkerk, Netherlands as the seventh child of Christiaan Eijkman, the headmaster of a local school, and Johanna Alida Pool. His elder brother Johann Frederik Eijkman (1851–1915) was also a chemist. A year later, in 1859, the Eijkman family moved to Zaandam, where his father was appointed head of a newly founded school for advanced elementary education. It was here that Christiaan and his brothers received their early education. In 1875, after taking his preliminary examinations, Eijkman became a student at the Military Medical School of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vitamin B1
Thiamine, also known as thiamin and vitamin B1, is a vitamin, an essential micronutrient, that cannot be made in the body. It is found in food and commercially synthesized to be a dietary supplement or medication. Phosphorylated forms of thiamine are required for some metabolic reactions, including the breakdown of glucose and amino acids. Food sources of thiamine include whole grains, legumes, and some meats and fish. Grain processing removes much of the vitamin content, so in many countries cereals and flours are enriched with thiamine. Supplements and medications are available to treat and prevent thiamine deficiency and disorders that result from it include beriberi and Wernicke encephalopathy. They are also used to treat maple syrup urine disease and Leigh syndrome. Supplements and medications are typically taken by mouth, but may also be given by intravenous or intramuscular injection. Thiamine supplements are generally well tolerated. Allergic reactions, including a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thiamine
Thiamine, also known as thiamin and vitamin B1, is a vitamin, an essential micronutrient, that cannot be made in the body. It is found in food and commercially synthesized to be a dietary supplement or medication. Phosphorylated forms of thiamine are required for some metabolic reactions, including the breakdown of glucose and amino acids. Food sources of thiamine include whole grains, legumes, and some meats and fish. Grain processing removes much of the vitamin content, so in many countries cereals and flours are enriched with thiamine. Supplements and medications are available to treat and prevent thiamine deficiency and disorders that result from it include beriberi and Wernicke encephalopathy. They are also used to treat maple syrup urine disease and Leigh syndrome. Supplements and medications are typically taken by mouth, but may also be given by intravenous or intramuscular injection. Thiamine supplements are generally well tolerated. Allergic reactions, including ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Johann Frederik Eijkman
Johan Fredrik Eykman or Johann Frederik Eijkman (19 January 1851 – 7 January 1915) was a Dutch chemist. Family background He is one of the eight children of Christiaan Eijkman, the headmaster of a local school, and Johanna Alida Pool. His brother Christiaan Eijkman (1858–1930) was a physician and professor of physiology whose demonstration that beriberi is caused by poor diet led to the discovery of vitamins. Together with Sir Frederick Hopkins, his brother received the Nobel Prize for Physiology or Medicine. Life in Japan He was hired during the Meiji period, a Japanese era which extended from September 1868 through July 1912. During his stay in Japan, he was the first to isolate shikimic acid in 1885 from the Japanese flower shikimi (シキミ, the Japanese star anise ''Illicium anisatum'', with common names Japanese star anise, Aniseed tree, and sacred Anise tree, known in Japan as , is a tree closely related to the Chinese star anise (''Illicium verum)''. S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beriberi
Thiamine deficiency is a medical condition of low levels of thiamine (Vitamin B1). A severe and chronic form is known as beriberi. The two main types in adults are wet beriberi and dry beriberi. Wet beriberi affects the cardiovascular system, resulting in a fast heart rate, shortness of breath, and leg swelling. Dry beriberi affects the nervous system, resulting in numbness of the hands and feet, confusion, trouble moving the legs, and pain. A form with loss of appetite and constipation may also occur. Another type, acute beriberi, found mostly in babies, presents with loss of appetite, vomiting, lactic acidosis, changes in heart rate, and enlargement of the heart. Risk factors include a diet of mostly white rice, alcoholism, dialysis, chronic diarrhea, and taking high doses of diuretics. In rare cases, it may be due to a genetic condition that results in difficulties absorbing thiamine found in food. Wernicke encephalopathy and Korsakoff syndrome are forms of dry beriberi. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adolphe Vorderman
Adolphe Guillaume Vorderman (12 December 1844 – 15 July 1902) was a Dutch physician and scientist whose study of the link between polished rice and beriberi in the Dutch East Indies in 1897 helped lead to the discovery of vitamins. In addition, he was an ornithologist and botanist. His great-granddaughter is British television presenter Carol Vorderman. Biography Vorderman, who was born in The Hague, first travelled to the Dutch East Indies in 1866 as a Naval Medical Officer. In 1871 he joined the Civil Health Department, and was stationed at Sumenep on the island of Madura until 1881 when he was transferred to Batavia (now Jakarta). From 1890 until his death in Batavia, he served as Chief Inspector of the department. Beriberi study In 1883 the Dutch government sent Christiaan Eijkman to the Dutch East Indies (now Indonesia) to try to determine the cause of and find a cure for beriberi. He noticed that chickens fed polished rice – which is rice which has had its bran ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nijkerk
Nijkerk (; Dutch Low Saxon: ''Niekark'') is a municipality and a city located in the middle of the Netherlands, in the province of Gelderland. Population centres Some people state that ''Groot Corlaer'' is a population centre on its own, but it is officially part of Nijkerk. Transportation Railway station: Nijkerk The city of Nijkerk The name Nijkerk stems from Nieuwe Kerk (Dutch for New Church). This new church was built after the old chapel had been destroyed by fire in 1221. Nijkerk was strategically located between the Duchy of Guelders ''(Dutch: Hertogdom Gelre)'' and the Bishopric of Utrecht. Because of this strategic location Nijkerk regularly was the scene of war, and in 1412 the village was completely destroyed. It was restored and Nijkerk received city rights in 1413. In 1421 the church that gave Nijkerk its name burnt down and was replaced; this happened several times, until a new church, the ''Grote-of-Sint-Catharinakerk''; was built in the 18th century. It sti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Amsterdam
The University of Amsterdam (abbreviated as UvA, nl, Universiteit van Amsterdam) is a public research university located in Amsterdam, Netherlands. The UvA is one of two large, publicly funded research universities in the city, the other being the Vrije Universiteit Amsterdam (VU). Established in 1632 by municipal authorities and later renamed for the city of Amsterdam, the University of Amsterdam is the third-oldest university in the Netherlands. It is one of the largest research universities in Europe with 31,186 students, 4,794 staff, 1,340 PhD students and an annual budget of €600 million. It is the largest university in the Netherlands by enrollment. The main campus is located in central Amsterdam, with a few faculties located in adjacent boroughs. The university is organised into seven faculties: Humanities, Social and Behavioural Sciences, Economics and Business, Science, Law, Medicine, Dentistry. The University of Amsterdam has produced six Nobel Laureates and fiv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Beriberi
Thiamine deficiency is a medical condition of low levels of thiamine (Vitamin B1). A severe and chronic form is known as beriberi. The two main types in adults are wet beriberi and dry beriberi. Wet beriberi affects the cardiovascular system, resulting in a fast heart rate, shortness of breath, and leg swelling. Dry beriberi affects the nervous system, resulting in numbness of the hands and feet, confusion, trouble moving the legs, and pain. A form with loss of appetite and constipation may also occur. Another type, acute beriberi, found mostly in babies, presents with loss of appetite, vomiting, lactic acidosis, changes in heart rate, and enlargement of the heart. Risk factors include a diet of mostly white rice, alcoholism, dialysis, chronic diarrhea, and taking high doses of diuretics. In rare cases, it may be due to a genetic condition that results in difficulties absorbing thiamine found in food. Wernicke encephalopathy and Korsakoff syndrome are forms of dry beriberi. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vitamin
A vitamin is an organic molecule (or a set of molecules closely related chemically, i.e. vitamers) that is an Nutrient#Essential nutrients, essential micronutrient that an organism needs in small quantities for the proper functioning of its metabolism. Essential nutrients cannot be biosynthesis, synthesized in the organism, either at all or not in sufficient quantities, and therefore must be obtained through the Diet (nutrition), diet. Vitamin C can be synthesized by some species but not by others; it is not a vitamin in the first instance but is in the second. The term ''vitamin'' does not include the three other groups of essential nutrients: mineral (nutrient), minerals, essential fatty acids, and essential amino acids. Most vitamins are not single molecules, but groups of related molecules called vitamers. For example, there are eight vitamers of vitamin E: four tocopherols and four tocotrienols. Some sources list fourteen vitamins, by including choline, but major health ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vitamin
A vitamin is an organic molecule (or a set of molecules closely related chemically, i.e. vitamers) that is an Nutrient#Essential nutrients, essential micronutrient that an organism needs in small quantities for the proper functioning of its metabolism. Essential nutrients cannot be biosynthesis, synthesized in the organism, either at all or not in sufficient quantities, and therefore must be obtained through the Diet (nutrition), diet. Vitamin C can be synthesized by some species but not by others; it is not a vitamin in the first instance but is in the second. The term ''vitamin'' does not include the three other groups of essential nutrients: mineral (nutrient), minerals, essential fatty acids, and essential amino acids. Most vitamins are not single molecules, but groups of related molecules called vitamers. For example, there are eight vitamers of vitamin E: four tocopherols and four tocotrienols. Some sources list fourteen vitamins, by including choline, but major health ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dutch East Indies
The Dutch East Indies, also known as the Netherlands East Indies ( nl, Nederlands(ch)-Indië; ), was a Dutch colony consisting of what is now Indonesia. It was formed from the nationalised trading posts of the Dutch East India Company, which came under the administration of the Dutch government in 1800. During the 19th century, the Dutch possessions and hegemony expanded, reaching the greatest territorial extent in the early 20th century. The Dutch East Indies was one of the most valuable colonies under European rule, and contributed to Dutch global prominence in spice and cash crop trade in the 19th to early 20th centuries. The colonial social order was based on rigid racial and social structures with a Dutch elite living separate from but linked to their native subjects. The term ''Indonesia'' came into use for the geographical location after 1880. In the early 20th century, local intellectuals began developing the concept of Indonesia as a nation state, and set the stage ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
