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Edward Mellanby
Sir Edward Mellanby (8 April 1884 – 30 January 1955) was a British biochemist and nutritionist who discovered vitamin D and its role in preventing rickets in 1919. Education Mellanby was born in West Hartlepool, the son of a shipyard owner, and educated at Barnard Castle School and Emmanuel College, Cambridge, where he studied physiology. Career After working as a research student from 1905 to 1907, Mellanby studied medicine at St. Thomas's Hospital in London, and in 1913 became a medical doctor. He served as a lecturer at King's College for Women in London from 1913 to 1920, during which time he was asked to investigate the cause of rickets. He discovered that feeding caged dogs on a diet of porridge induced rickets, which could then be cured with cod liver oil and concluded that rickets was caused by a dietary factor. It was later discovered that the actual cause of rickets is lack of vitamin D due to lack of sunlight which can be prevented or remedied by ingesting food r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Research Council (UK)
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy. The MRC focuses on high-impact research and has provided the financial support and scientific expertise behind a number of medical breakthroughs, including the development of penicillin and the discovery of the structure of DNA. Research funded by the MRC has produced 32 Nobel Prize winners to date. History The MRC was founded as the Medical Research Committee and Advisory Council in 1913, with its prime role being the distribution of medical research funds under the terms of the National Insurance Act 1911. This was a consequen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
West Hartlepool
West Hartlepool was a predecessor of Hartlepool, County Durham, England. It developed in the Victorian era and took the name from its western position in the parish of what is now known as the Headland. The former town was originally formed in 1848 as an accompanying settlement for nearby railway and docks, which brought and exported coal from the area. The rail network grew, connecting to docks in Leeds and other cities. Further developments in the area led to the 1960s formation of Hartlepool as a town. History The town of West Hartlepool was founded by Ralph Ward Jackson who went on to become managing director of the Stockton and Hartlepool Railway in 1848. The area known as Newburn Raw, part of the ancient village of Stranton, steadily grew into a centre for shipping and railway transportation. The West Hartlepool Harbour and Dock () opened on 1 June 1847. Five years later, also on 1 June, the Jackson dock () opened as well as a railway connecting West Hartlepool to Leeds ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phytic Acid
Phytic acid is a six-fold dihydrogenphosphate ester of inositol (specifically, of the ''myo'' isomer), also called inositol hexakisphosphate (IP6) or inositol polyphosphate. At physiological pH, the phosphates are partially ionized, resulting in the phytate anion. The (''myo'') phytate anion is a colorless species that has significant nutritional role as the principal storage form of phosphorus in many plant tissues, especially bran and seeds. It is also present in many legumes, cereals, and grains. Phytic acid and phytate have a strong binding affinity to the dietary minerals, calcium, iron, and zinc, inhibiting their absorption in the small intestine. The lower inositol polyphosphates are inositol esters with less than six phosphates, such as inositol penta- (IP5), tetra- (IP4), and triphosphate (IP3). These occur in nature as catabolites of phytic acid. Significance in agriculture Phytic acid was discovered in 1903. Generally, phosphorus and inositol in phytate form ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Grafton Elliot Smith
Sir Grafton Elliot Smith (15 August 1871 – 1 January 1937) was an Australian-British anatomist, Egyptologist and a proponent of the hyperdiffusionist view of prehistory. He believed in the idea that cultural innovations occur only once and that they spread geographically. Based on this, he traced the origins of many cultural and traditional practices across the world, including the New World, to ideas that he believed came from Egypt and in some instances from Asia. An expert on brain anatomy, he was one of the first to study Egyptian mummies using radiological techniques. He took an interest in extinct humanoids and was embroiled in controversy over the authenticity of the Piltdown Man. Professional career Smith was born in Grafton, New South Wales to Stephen Sheldrick Smith who had moved to Australia from London in 1860 and Mary Jane, née Evans. He received his early education from Grafton Public School where his father was headmaster. When the family moved to Sydney in 1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harveian Oration
The Harveian Oration is a yearly lecture held at the Royal College of Physicians of London. It was instituted in 1656 by William Harvey, discoverer of the systemic circulation. Harvey made financial provision for the college to hold an annual feast on St. Luke's Day (18 October) at which an oration would be delivered in Latin to praise the college's benefactors and ''to exhort the Fellows and Members of this college to search and study out the secrets of nature by way of experiment''. Until 1865, the Oration was given in Latin, as Harvey had specified, and known as the ''Oratio anniversaria''; but it was thereafter spoken in English. Many of the lectures were published in book form. Lecturers (incomplete list) 1656–1700 *1656 Edward Emily *1657 Edmund Wilson *1659 Daniel Whistler *1660 Thomas Coxe *1661 Edward Greaves *1662 Charles Scarburgh *1663 Christopher Terne *1664 Nathan Paget *1665 Samuel Collins *1666-1678 No Orations due to rebuilding following Great Fire of Lo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vitamin Deficiency
Vitamin deficiency is the condition of a long-term lack of a vitamin. When caused by not enough vitamin intake it is classified as a ''primary deficiency'', whereas when due to an underlying disorder such as malabsorption it is called a ''secondary deficiency''. An underlying disorder may be metabolic – as in a genetic defect for converting tryptophan to niacin – or from lifestyle choices that increase vitamin needs, such as smoking or drinking alcohol. Government guidelines on vitamin deficiencies advise certain intakes for healthy people, with specific values for women, men, babies, the elderly, and during pregnancy or breastfeeding. Many countries have mandated vitamin food fortification programs to prevent commonly occurring vitamin deficiencies. Conversely, hypervitaminosis refers to symptoms caused by vitamin intakes in excess of needs, especially for fat-soluble vitamins that can accumulate in body tissues. The history of the discovery of vitamin deficiencies progre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Knight Grand Cross Of The British Empire
The Most Excellent Order of the British Empire is a British order of chivalry, rewarding contributions to the arts and sciences, work with charitable and welfare organisations, and public service outside the civil service. It was established on 4 June 1917 by King George V and comprises five classes across both civil and military divisions, the most senior two of which make the recipient either a knight if male or dame if female. There is also the related British Empire Medal, whose recipients are affiliated with, but not members of, the order. Recommendations for appointments to the Order of the British Empire were originally made on the nomination of the United Kingdom, the self-governing Dominions of the Empire (later Commonwealth) and the Viceroy of India. Nominations continue today from Commonwealth countries that participate in recommending British honours. Most Commonwealth countries ceased recommendations for appointments to the Order of the British Empire when they cre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Order Of The Bath
The Most Honourable Order of the Bath is a British order of chivalry founded by George I of Great Britain, George I on 18 May 1725. The name derives from the elaborate medieval ceremony for appointing a knight, which involved Bathing#Medieval and early-modern Europe, bathing (as a symbol of purification) as one of its elements. The knights so created were known as "Knights of the Bath". George I "erected the Knights of the Bath into a regular Order (honour), Military Order". He did not (as is commonly believed) revive the Order of the Bath, since it had never previously existed as an Order, in the sense of a body of knights who were governed by a set of Statute, statutes and whose numbers were replenished when vacancies occurred. The Order consists of the Sovereign (currently Charles III, King Charles III), the :Great Masters of the Order of the Bath, Great Master (currently vacant) and three Classes of members: *Knight Grand Cross (:Knights Grand Cross of the Order of the Bath ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal College Of Physicians
The Royal College of Physicians (RCP) is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of physicians by examination. Founded by royal charter from King Henry VIII in 1518, the RCP is the oldest medical college in England. It set the first international standard in the classification of diseases, and its library contains medical texts of great historical interest. The college is sometimes referred to as the Royal College of Physicians of London to differentiate it from other similarly named bodies. The RCP drives improvements in health and healthcare through advocacy, education and research. Its 40,000 members work in hospitals and communities across over 30 medical specialties with around a fifth based in over 80 countries worldwide. The college hosts six training faculties: the Faculty of Forensic and Legal Medicine, the Faculty for Pharmaceutical Medicine, the Faculty of Occupational Medicine the Fac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Croonian Lecture
The Croonian Medal and Lecture is a prestigious award, a medal, and lecture given at the invitation of the Royal Society and the Royal College of Physicians. Among the papers of William Croone at his death in 1684, was a plan to endow a single lectureship at both the Royal Society and the Royal College of Physicians The Royal College of Physicians (RCP) is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of physicians by examination. Founded by royal charter from King Henry VIII in 1 .... His wife provided the bequest in 1701 specifying that it was "for the support of a lecture and illustrative experiment for the advancement of natural knowledge on locomotion, or (conditionally) of such other subjects as, in the opinion of the President for the time being, should be most useful in promoting the objects for which the Royal Society was instituted". One lecture was to be delivered by a Fellow of the Royal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacology
Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous (from within the body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word ''pharmacon'' is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties,functions,sources,synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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