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EUginius
EUginius is an Internet-based database application for Genetically modified organisms (GMOs). The name EUginius is an acronym and stands for EUropean GMO Initiative for a Unified Database System. Development and commissioning The EUginius database was created on the initiative of the German Federal Office of Consumer Protection and Food Safety (BVL) and the Dutch research Institute Wageningen Food Safety Research (WFSR, formerly RIKILT). Building on parallel preparatory work by both cooperation partners, EUginius has been jointly developed and maintained since 2010, and has been online since October 2014. The information is provided in English. Goal EUginius aims to assist competent authorities as well as interested private users in finding accurate information on the presence, detection and identification of GMOs. Data on the GMOs’ molecular characterisation and traits, detection methods, reference materials, and authorisation status (currently limited to the EU) are provi ...
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Genetically Modified Organism
A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques. The exact definition of a genetically modified organism and what constitutes genetic engineering varies, with the most common being an organism altered in a way that "does not occur naturally by mating and/or natural recombination". A wide variety of organisms have been genetically modified (GM), from animals to plants and microorganisms. Genes have been transferred within the same species, across species (creating transgenic organisms), and even across kingdoms. New genes can be introduced, or endogenous genes can be enhanced, altered, or knocked out. Creating a genetically modified organism is a multi-step process. Genetic engineers must isolate the gene they wish to insert into the host organism and combine it with other genetic elements, including a promoter and terminator region and often a selectable marker. A number of techniques are a ...
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Federal Office Of Consumer Protection And Food Safety
The Federal Office of Consumer Protection and Food Safety (BVL) is an agency of the German government that comes under Federal Ministry of Food and Agriculture (BMEL). It contributes towards food safety and grants authorization. It jointly coordinates monitoring programs with federal states A federation (also known as a federal state) is a political entity characterized by a union of partially self-governing provinces, states, or other regions under a central federal government (federalism). In a federation, the self-governi .... Within the framework of the European rapid alert system, the BVL secures the flow of information between the EU and the Federal States. It is also the German contact point for the inspections of the Food and Veterinary Office of the European Commission. Apart from that, the BVL supports the Federal Ministry of Food and Agriculture in crisis management. References External links BVL-Website Consumer rights agencies Consumer organisations ...
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Triticum Aestivum
Common wheat (''Triticum aestivum''), also known as bread wheat, is a cultivated wheat species. About 95% of wheat produced worldwide is common wheat; it is the most widely grown of all crops and the cereal with the highest monetary yield. Taxonomy Numerous forms of wheat have evolved under human selection. This diversity has led to confusion in the naming of wheats, with names based on both genetic and morphological characteristics. List of common cultivars * Albimonte * Manital Phylogeny Bread wheat is an allohexaploid (an allopolyploid with six sets of chromosomes: two sets from each of three different species). Of the six sets of chromosomes, two come from ''Triticum urartu'' (einkorn wheat) and two from a species related to ''Aegilops speltoides''. This spontaneous hybridisation created the tetraploid species ''Triticum turgidum'' (an ancestor of wild emmer wheat and durum wheat) 580,000–820,000 years ago. The last two sets of chromosomes came from wild goat-gra ...
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Genetically Modified Maize
Genetically modified maize (corn) is a genetically modified crop. Specific maize strains have been genetically engineered to express agriculturally-desirable traits, including resistance to pests and to herbicides. Maize strains with both traits are now in use in multiple countries. GM maize has also caused controversy with respect to possible health effects, impact on other insects and impact on other plants via gene flow. One strain, called Starlink, was approved only for animal feed in the US but was found in food, leading to a series of recalls starting in 2000. Marketed products Herbicide-resistant maize Corn varieties resistant to glyphosate herbicides were first commercialized in 1996 by Monsanto, and are known as "Roundup Ready Corn". They tolerate the use of Roundup. Bayer CropScience developed "Liberty Link Corn" that is resistant to glufosinate. Pioneer Hi-Bred has developed and markets corn hybrids with tolerance to imidazoline herbicides under the trademark ...
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Golden Rice
Golden rice is a variety of rice (''Oryza sativa'') produced through genetic engineering to biosynthesize beta-carotene, a precursor of vitamin A, in the edible parts of the rice. It is intended to produce a fortified food to be grown and consumed in areas with a shortage of dietary vitamin A. Vitamin A deficiency causes xerophthalmia, a range of eye conditions from night blindness to more severe clinical outcomes such as keratomalacia and corneal scars, and permanent blindness. It also increases risk of mortality from measles and diarrhea in children. In 2013, the prevalence of deficiency was the highest in sub-Saharan Africa (48%; 25–75), and South Asia (44%; 13–79). Although golden rice has met significant opposition from environmental and anti-globalisation activists, more than 100 Nobel laureates in 2016 encouraged use of genetically modified golden rice which can produce up to 23 times as much beta-carotene as the original golden rice. History Research for develo ...
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AquAdvantage Salmon
AquAdvantage salmon is a genetically engineered (GE) fish, a GE Atlantic salmon developed by AquaBounty Technologies in 1989. The typical growth hormone-regulating gene in the Atlantic salmon was replaced with the growth hormone-regulating gene from Pacific Chinook salmon, with a promoter sequence from ocean pout. This gene enables the GM salmon to grow year-round instead of only during spring and summer. These GE salmon are a commercially competitive alternative to wild-caught salmon and to fish farming of unmodified salmon. The purpose of the modifications is to increase the speed at which the fish grows without affecting its ultimate size or other qualities. Fish-farmed Atlantic salmon growth rates have already been improved over wild fish as a result of traditional selective breeding practices. However, GM fish are able to grow even faster and grow to market size in just 16 to 18 months rather than three years. Significance AquAdvantage salmon are the first genetically en ...
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New Breeding Techniques
New Breeding Techniques (NBT), also named ''New Plant Engineering Techniques,'' are a suite of methods that could increase and accelerate the development of new traits in plant breeding. These new techniques, often involve 'genome editing' whose intention is to modify DNA at specific locations within the plants' genes so that new traits and properties are produced in crop plants. An ongoing discussion in many countries is as to whether NBTs should be included within the same pre-existing governmental regulations to control genetic modification. Methods involved New breeding techniques (NBTs) make specific changes within plant DNA in order to change its traits, and these modifications can vary in scale from altering single base, to inserting or removing one or more genes. The various methods of achieving these changes in traits include the following: * Cutting and modifying the genome during the repair process (three tools are used to achieve this: Zinc finger nuclease; TALENs, ...
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Polymerase Chain Reaction
The polymerase chain reaction (PCR) is a method widely used to rapidly make millions to billions of copies (complete or partial) of a specific DNA sample, allowing scientists to take a very small sample of DNA and amplify it (or a part of it) to a large enough amount to study in detail. PCR was invented in 1983 by the American biochemist Kary Mullis at Cetus Corporation; Mullis and biochemist Michael Smith (chemist), Michael Smith, who had developed other essential ways of manipulating DNA, were jointly awarded the Nobel Prize in Chemistry in 1993. PCR is fundamental to many of the procedures used in genetic testing and research, including analysis of Ancient DNA, ancient samples of DNA and identification of infectious agents. Using PCR, copies of very small amounts of DNA sequences are exponentially amplified in a series of cycles of temperature changes. PCR is now a common and often indispensable technique used in medical laboratory research for a broad variety of applications ...
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Certified Reference Materials
Certified reference materials (CRMs) are 'controls' or standards used to check the quality and metrological traceability of products, to validate analytical measurement methods, or for the calibration of instruments. A certified reference material is a particular form of measurement standard. Reference materials are particularly important for analytical chemistry and clinical analysis. Since most analytical instrumentation is comparative, it requires a sample of known composition (reference material) for accurate calibration. These reference materials are produced under stringent manufacturing procedures and differ from laboratory reagents in their certification and the traceability of the data provided. Quality management systems involving laboratory accreditation under national and international accreditation/certification standards such as ISO/IEC 17025 require metrological traceability to Certified Reference Materials (where possible) when using reference materials for ca ...
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Genetic Engineering
Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA is obtained by either isolating and copying the genetic material of interest using recombinant DNA methods or by artificially synthesising the DNA. A construct is usually created and used to insert this DNA into the host organism. The first recombinant DNA molecule was made by Paul Berg in 1972 by combining DNA from the monkey virus SV40 with the lambda virus. As well as inserting genes, the process can be used to remove, or "knock out", genes. The new DNA can be inserted randomly, or targeted to a specific part of the genome. An organism that is generated through genetic engineering is considered to be genetically modified (GM) an ...
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