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Drifty Gene Hypothesis
The "drifty gene hypothesis" was proposed by the British biologist John Speakman as an alternative to the thrifty gene hypothesis originally proposed by James V Neel in 1962. Speakman's critique of the thrifty gene hypothesis is based on an analysis of the pattern and level of mortality during famines. Despite much anecdotal evidence used to suggest that famines cause substantial mortality, Speakman suggests that where real data are available famines actually involve rather low levels of mortality and there is no evidence that fat people survive famines better than lean people. In fact, mortality actually falls mostly on groups such as the very young and very old where differential mortality in relation to body composition is highly unlikely. Moreover, there is some confusion among proponents of the thrifty gene hypothesis about how long famines have played a role in evolution. On the one hand some proponents suggest famines have been an "ever present" threat dating back to the daw ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Speakman
John Roger Speakman (born 1958) is a British biologist working at the University of Aberdeen, Institute of Biological and Environmental Sciences, for which he was Director from 2007 to 2011. He leads the University's Energetics Research Group, which is one of the world's leading groups using doubly labeled water (DLW) to investigate energy expenditure and balance in animals. One or more of the preceding sentences incorporates text from the royalsociety.org website where: Between 2011-2020, he was a '1000 talents' Professor at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, in Beijing, China, where he ran the molecular energetics group. In 2020 he moved to the Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences in Shenzhen, China where he works at the Center for Energy Metabolism and Reproduction and Head of the Shenzhen Key laboratory of Metabolic Health. Education Speakman was educated at Leigh Grammar School, near Man ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thrifty Gene Hypothesis
The thrifty gene hypothesis, or Gianfranco's hypothesis is an attempt by geneticist James V. Neel to explain why certain populations and subpopulations in the modern day are prone to diabetes mellitus type 2. He proposed the hypothesis in 1962 to resolve a fundamental problem: diabetes is clearly a very harmful medical condition, yet it is quite common, and it was already evident to Neel that it likely had a strong genetic basis. The problem is to understand how disease with a likely genetic component and with such negative effects may have been favoured by the process of natural selection. Neel suggested the resolution to this problem is that genes which predispose to diabetes (called 'thrifty genes') were historically advantageous, but they became detrimental in the modern world. In his words they were "rendered detrimental by 'progress'". Neel's primary interest was in diabetes, but the idea was soon expanded to encompass obesity as well. Thrifty genes are genes which enable indiv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Famine
A famine is a widespread scarcity of food, caused by several factors including war, natural disasters, crop failure, population imbalance, widespread poverty, an economic catastrophe or government policies. This phenomenon is usually accompanied or followed by regional malnutrition, starvation, epidemic, and increased mortality. Every inhabited continent in the world has experienced a period of famine throughout history. In the 19th and 20th century, generally characterized Southeast and South Asia, as well as Eastern and Central Europe, in terms of having suffered most number of deaths from famine. The numbers dying from famine began to fall sharply from the 2000s. Since 2010, Africa has been the most affected continent of famine in the world. Definitions According to the United Nations World Food Programme, famine is declared when malnutrition is widespread, and when people have started dying of starvation through lack of access to sufficient, nutritious food. The Integrate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Australopithecine
Australopithecina or Hominina is a subtribe in the tribe Hominini. The members of the subtribe are generally ''Australopithecus'' (cladistically including the genera ''Homo'', '' Paranthropus'', and ''Kenyanthropus''), and it typically includes the earlier ''Ardipithecus'', ''Orrorin'', ''Sahelanthropus'', and ''Graecopithecus''. All these closely related species are now sometimes collectively termed australopiths or homininians. They are the extinct, close relatives of humans and, with the extant genus ''Homo'', comprise the human clade. Members of the human clade, i.e. the Hominini after the split from the chimpanzees, are now called Hominina (''see Hominidae; terms "hominids" and hominins''). While none of the groups normally directly assigned to this group survived, the australopiths do not appear to be literally extinct (in the sense of having no living descendants) as the genera ''Kenyanthropus'', ''Paranthropus'' and ''Homo'' probably emerged as sister of a late ''Aus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
History Of Agriculture
Agriculture began independently in different parts of the globe, and included a diverse range of taxa. At least eleven separate regions of the Old and New World were involved as independent centers of origin. The development of agriculture about 12,000 years ago changed the way humans lived. They switched from nomadic hunter-gatherer lifestyles to permanent settlements and farming. Wild grains were collected and eaten from at least 105,000 years ago. However, domestication did not occur until much later. The earliest evidence of small-scale cultivation of edible grasses is from around 21,000 BC with the Ohalo II people on the shores of the Sea of Galilee. By around 9500 BC, the eight Neolithic founder crops – emmer wheat, einkorn wheat, hulled barley, peas, lentils, bitter vetch, chickpeas, and flax – were cultivated in the Levant. Rye may have been cultivated earlier, but this claim remains controversial. Rice was domesticated in China by 6200 BC wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Drift
Genetic drift, also known as allelic drift or the Wright effect, is the change in the frequency of an existing gene variant (allele) in a population due to random chance. Genetic drift may cause gene variants to disappear completely and thereby reduce genetic variation. It can also cause initially rare alleles to become much more frequent and even fixed. When few copies of an allele exist, the effect of genetic drift is more notable, and when many copies exist, the effect is less notable. In the middle of the 20th century, vigorous debates occurred over the relative importance of natural selection versus neutral processes, including genetic drift. Ronald Fisher, who explained natural selection using Mendelian genetics, held the view that genetic drift plays at most a minor role in evolution, and this remained the dominant view for several decades. In 1968, population geneticist Motoo Kimura rekindled the debate with his neutral theory of molecular evolution, which claims that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Predation
Predation is a biological interaction where one organism, the predator, kills and eats another organism, its prey. It is one of a family of common feeding behaviours that includes parasitism and micropredation (which usually do not kill the host) and parasitoidism (which always does, eventually). It is distinct from scavenging on dead prey, though many predators also scavenge; it overlaps with herbivory, as seed predators and destructive frugivores are predators. Predators may actively search for or pursue prey or wait for it, often concealed. When prey is detected, the predator assesses whether to attack it. This may involve ambush or pursuit predation, sometimes after stalking the prey. If the attack is successful, the predator kills the prey, removes any inedible parts like the shell or spines, and eats it. Predators are adapted and often highly specialized for hunting, with acute senses such as vision, hearing, or smell. Many predatory animals, both vertebrate an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetics Of Obesity
Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. Studies have identified variants in several genes that may contribute to weight gain and body fat distribution; although, only in a few cases are genes the primary cause of obesity. Polymorphisms in various genes controlling appetite and metabolism predispose to obesity under certain dietary conditions. The percentage of obesity that can be attributed to genetics varies widely, depending on the population examined, from 6% to 85%, with the typical estimate at 50%. It is likely that in each person a number of genes contribute to the likelihood of developing obesity in small part, with each gene increasing or decreasing the odds marginally, and together determining how an individual responds to the environmental factors. As of 2006, more than 41 sites on the human genome have been linked to the development of obesity when a favorable environment is present. Some ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New World Syndrome
New World Syndrome is a set of non-communicable diseases brought on by consumption of junk food and a sedentary lifestyle, especially common to indigenous peoples of the Americas, Oceania, and circumpolar peoples. It is characterized by obesity, heart disease, diabetes, hypertension, and shortened life span. Causes New World Syndrome is linked to a change from a traditional diet and exercise to a Western diet and a sedentary lifestyle. Traditional occupations of indigenous people—such as fishing, farming, and hunting—tended to involve constant activity, whereas modern office jobs do not. The introduction of modern transportation such as automobiles also decreased physical exertion. Meanwhile, Western foods which are rich in fat, salt, sugar, and refined starches are also imported into countries. The amount of carbohydrates in diets increases. Diagnosis The diagnosis does not require specific criteria. Obesity is often followed by its complications like hyperlipidemia, hype ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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