Dr. Jonathan Simons
   HOME
*





Dr. Jonathan Simons
Jonathan W. Simons is an American physician-scientist, medical oncologist, and leader in prostate cancer research. In August 2021, Simons was appointed the Medical Director and Chief Science Officer of the Marcus Foundation. Prior to joining the Marcus Foundation, he served a 14-year tenure as the President and chief executive officer of the Prostate Cancer Foundation. Simons’ laboratories, partly funded by the Prostate Cancer Foundation, at Johns Hopkins University and Emory University made original contributions to understanding the molecular biology of prostate cancer metastasis and principles of “broken immune tolerance” via T cell based immunotherapy for prostate cancer.  The Simons lab invented GM-CSF genetically engineered vaccines for prostate cancer in rodents and humans for these studies, and subsequently Simons’ clinical team took the biotechnology into the world’s first human gene therapy clinical trials for advanced prostate cancer at Johns Hopkins. Early ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Washington, D
Washington commonly refers to: * Washington (state), United States * Washington, D.C., the capital of the United States ** A metonym for the federal government of the United States ** Washington metropolitan area, the metropolitan area centered on Washington, D.C. * George Washington (1732–1799), the first president of the United States Washington may also refer to: Places England * Washington, Tyne and Wear, a town in the City of Sunderland metropolitan borough ** Washington Old Hall, ancestral home of the family of George Washington * Washington, West Sussex, a village and civil parish Greenland * Cape Washington, Greenland * Washington Land Philippines *New Washington, Aklan, a municipality *Washington, a barangay in Catarman, Northern Samar *Washington, a barangay in Escalante, Negros Occidental *Washington, a barangay in San Jacinto, Masbate *Washington, a barangay in Surigao City United States * Washington, Wisconsin (other) * Fort Washington (other) ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Ithaca High School (Ithaca, New York)
Ithaca High School (IHS) is a public high school in Ithaca, New York, USA. It is part of the Ithaca City School District, and has an enrollment of approximately 1,675. The school is located at 1401 North Cayuga Street in the north end of Ithaca, near Stewart Park, Cayuga Lake, and Ithaca Falls. The current principal is Jason Trumble. In 2017, '' U.S. News & World Report'' ranked IHS as the best high school in Central New York, 48th in New York State, and 401st nationwide. History Ithaca High School was founded in 1875 as the successor to the Ithaca Academy, a private school that had operated since the 1820s. In the late 19th and early 20th century, the school had a significant side business as a tuition-charging college preparatory school; then-Cornell University President Jacob Gould Schurman called it "one of the finest in the Northeast." A new building for the high school on the site of the former academy was built in 1885; that building burned on February 14, 1912. The ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

National Cancer Institute
The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. The NCI conducts and supports research, training, health information dissemination, and other activities related to the causes, prevention, diagnosis, and treatment of cancer; the supportive care of cancer patients and their families; and cancer survivorship. NCI is the oldest and has the largest budget and research program of the 27 institutes and centers of the NIH ($6.9 billion in 2020). It fulfills the majority of its mission via an extramural program that provides grants for cancer research. Additionally, the National Cancer Institute has intramural research programs in Bethesda, Maryland, and at the Frederick National Laboratory for Cancer Research at Fort Detrick in Frederick, Maryland. The NCI receives more than in funding each ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Cancer Research
Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments. These applications include surgery, radiation therapy, chemotherapy, hormone therapy, immunotherapy and combined treatment modalities such as chemo-radiotherapy. Starting in the mid-1990s, the emphasis in clinical cancer research shifted towards therapies derived from biotechnology research, such as cancer immunotherapy and gene therapy. Cancer research is done in academia, research institutes, and corporate environments, and is largely government funded. History Cancer research has been ongoing for centuries. Early research focused on the causes of cancer. Percivall Pott identified the first environmental trigger (chimney soot) for cancer in 1775 and cigarette smoking was identif ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Winship Cancer Institute
Winship Cancer Institute of Emory University is a nonprofit cancer research and patient care center based in Atlanta, Georgia. Winship Cancer Institute is the only National Cancer Institute-designated Comprehensive Cancer Center in Georgia. History The Robert Winship Clinic was established in 1937 through a gift to Emory of $50,000 from Coca-Cola CEO Robert W. Woodruff, who named the center after his maternal grandfather, Robert Winship, in honor of his mother, Emily Winship, who died from breast cancer. Woodruff’s vision was to create a center in Georgia that focuses on research, education and patient care. The Robert W. Woodruff Foundation, Inc. has continued to support Emory in achieving this vision, and in 2003 Emory dedicated the Winship Cancer Institute building, constructed with funds from the Robert W. Woodruff Foundation, Inc. Locations Winship Cancer Institute is located on the campus of Emory University in Atlanta, Georgia. Affiliate locations include Emory Univer ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Robert W
The name Robert is an ancient Germanic given name, from Proto-Germanic "fame" and "bright" (''Hrōþiberhtaz''). Compare Old Dutch ''Robrecht'' and Old High German ''Hrodebert'' (a compound of '' Hruod'' ( non, Hróðr) "fame, glory, honour, praise, renown" and ''berht'' "bright, light, shining"). It is the second most frequently used given name of ancient Germanic origin. It is also in use as a surname. Another commonly used form of the name is Rupert. After becoming widely used in Continental Europe it entered England in its Old French form ''Robert'', where an Old English cognate form (''Hrēodbēorht'', ''Hrodberht'', ''Hrēodbēorð'', ''Hrœdbœrð'', ''Hrœdberð'', ''Hrōðberχtŕ'') had existed before the Norman Conquest. The feminine version is Roberta. The Italian, Portuguese, and Spanish form is Roberto. Robert is also a common name in many Germanic languages, including English, German, Dutch, Norwegian, Swedish, Scots, Danish, and Icelandic. It can be use ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Roy Barnes
Roy Eugene Barnes (born March 11, 1948)Cook, James F. (2005). ''The Governors of Georgia, 1754-2004, 3rd Edition, Revised and Expanded.'' Macon, GA: Mercer University Press. is an American attorney and politician who served as the 80th Governor of the U.S. State of Georgia from 1999 to 2003. , he is the most recent Democrat to hold the office of Governor of Georgia. A Democratic member of the Georgia Senate from 1974 to 1990, Barnes ran unsuccessfully for Governor in 1990, losing to Lieutenant Governor Zell Miller in the Democratic primary. Barnes then served in the Georgia House of Representatives from 1992 to 1998. He ran for governor again in 1998, handily winning the primary and general elections. In 2003, Barnes was awarded the Profile in Courage Award by the John F. Kennedy Library for his success while Governor of minimizing the Confederate battle emblem on the Georgia state flag despite the political fallout.
[...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Georgia (U
Georgia most commonly refers to: * Georgia (country), a country in the Caucasus region of Eurasia * Georgia (U.S. state), a state in the Southeast United States Georgia may also refer to: Places Historical states and entities * Related to the country in the Caucasus ** Kingdom of Georgia, a medieval kingdom ** Georgia within the Russian Empire ** Democratic Republic of Georgia, established following the Russian Revolution ** Georgian Soviet Socialist Republic, a constituent of the Soviet Union * Related to the US state ** Province of Georgia, one of the thirteen American colonies established by Great Britain in what became the United States ** Georgia in the American Civil War, the State of Georgia within the Confederate States of America. Other places * 359 Georgia, an asteroid * New Georgia, Solomon Islands * South Georgia and the South Sandwich Islands Canada * Georgia Street, in Vancouver, British Columbia, Canada * Strait of Georgia, British Columbia, Canada United K ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  




Bert Vogelstein
Bert Vogelstein (born 1949) is director of the Ludwig Center, Clayton Professor of Oncology and Pathology and a Howard Hughes Medical Institute investigator at The Johns Hopkins Medical School and Sidney Kimmel Comprehensive Cancer Center. A pioneer in the field of cancer genomics, his studies on colorectal cancers revealed that they result from the sequential accumulation of mutations in oncogenes and tumor suppressor genes. These studies now form the paradigm for modern cancer research and provided the basis for the notion of the somatic evolution of cancer. Research In the 1980s, Vogelstein developed new experimental approaches to study human tumors. His studies of various stages of colorectal cancers led him to propose a specific model for human tumorigenesis in 1988. In particular, he suggested that "cancer is caused by sequential mutations of specific oncogenes and tumor suppressor genes". The first tumor suppressor gene validating this hypothesis was that encoding p53. T ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Massachusetts General Hospital
Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United States and has a capacity of 999 beds. With Brigham and Women's Hospital, it is one of the two founding members of Mass General Brigham (formerly known as Partners HealthCare), the largest healthcare provider in Massachusetts. Massachusetts General Hospital houses the largest hospital-based research program in the world, the Mass General Research Institute, with an annual research budget of more than $1 billion in 2019. It is currently ranked as the #8 best hospital in the United States by '' U.S. News & World Report''. In , ''The Boston Globe'' ranked MGH the fifth best place to work out of Massachusetts companies with over 1,000 employees. History Founded in 1811, the original hospital was designed by the famous American architect Char ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

University Of Cambridge
, mottoeng = Literal: From here, light and sacred draughts. Non literal: From this place, we gain enlightenment and precious knowledge. , established = , other_name = The Chancellor, Masters and Scholars of the University of Cambridge , type = Public research university , endowment = £7.121 billion (including colleges) , budget = £2.308 billion (excluding colleges) , chancellor = The Lord Sainsbury of Turville , vice_chancellor = Anthony Freeling , students = 24,450 (2020) , undergrad = 12,850 (2020) , postgrad = 11,600 (2020) , city = Cambridge , country = England , campus_type = , sporting_affiliations = The Sporting Blue , colours = Cambridge Blue , website = , logo = University of Cambridge logo ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Canterbury
Canterbury (, ) is a City status in the United Kingdom, cathedral city and UNESCO World Heritage Site, situated in the heart of the City of Canterbury local government district of Kent, England. It lies on the River Stour, Kent, River Stour. The Archbishop of Canterbury is the primate (bishop), primate of the Church of England and the worldwide Anglican Communion owing to the importance of Augustine of Canterbury, St Augustine, who served as the apostle to the Anglo-Saxon paganism, pagan Kingdom of Kent around the turn of the 7th century. The city's Canterbury Cathedral, cathedral became a major focus of Christian pilgrimage, pilgrimage following the 1170 Martyr of the Faith, martyrdom of Thomas Becket, although it had already been a well-trodden pilgrim destination since the murder of Ælfheah of Canterbury, St Alphege by the men of cnut, King Canute in 1012. A journey of pilgrims to Becket's shrine served as the narrative frame, frame for Geoffrey Chaucer's 14th-century Wes ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]