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Devil Facial Tumor Disease
Devil facial tumour disease (DFTD) is an aggressive non-viral clonally transmissible cancer which affects Tasmanian devils, a marsupial native to Australia. DFTD was first described in 1996. In the subsequent decade the disease ravaged Tasmania's wild devils. Affected high-density populations had up to 100% mortality in 12–18 months. Between 1996 and 2015, DFTD wiped out 95% of affected populations. Clinical signs There is often more than one primary tumour. Visible signs of DFTD begin with lumps of soft tissue around the mouth, which ulcerate. Tumours are locally aggressive, destroying the underlying bone of the jaw which interferes with feeding. Tumours may also cover the eyes. Devils usually die within six months from organ failure, secondary infection, or metabolic starvation. DFTD is rare in juveniles. It affects males and females equally. Transmission The most plausible route of transmission is through biting, particularly when canine teeth come into direct contact wi ...
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Tasmanian Devil Facial Tumour Disease
) , nickname = , image_map = Tasmania in Australia.svg , map_caption = Location of Tasmania in AustraliaCoordinates: , subdivision_type = Country , subdivision_name = Australia , established_title = Before federation , established_date = Colony of Tasmania , established_title2 = Federation , established_date2 = 1 January 1901 , named_for = Abel Tasman , demonym = , capital = Hobart , largest_city = capital , coordinates = , admin_center = 29 local government areas , admin_center_type = Administration , leader_title1 = Monarch , leader_name1 = Charles III , leader_title2 = Governor , leader_name ...
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Peripheral Nervous System
The peripheral nervous system (PNS) is one of two components that make up the nervous system of bilateral animals, with the other part being the central nervous system (CNS). The PNS consists of nerves and ganglia, which lie outside the brain and the spinal cord. The main function of the PNS is to connect the CNS to the limbs and organs, essentially serving as a relay between the brain and spinal cord and the rest of the body. Unlike the CNS, the PNS is not protected by the vertebral column and skull, or by the blood–brain barrier, which leaves it exposed to toxins. The peripheral nervous system can be divided into the somatic nervous system and the autonomic nervous system. In the somatic nervous system, the cranial nerves are part of the PNS with the exception of the optic nerve (cranial nerve II), along with the retina. The second cranial nerve is not a true peripheral nerve but a tract of the diencephalon. Cranial nerve ganglia, as with all ganglia, are pa ...
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Taroona
Taroona is a major residential suburb approximately 15 minutes drive from the centre of Hobart, Tasmania on the scenic route between Hobart and Kingston. Although on the edges of the City of Hobart, Taroona is actually part of the municipality of Kingborough. Taroona is bounded on the east by the Derwent River, and has several beaches along the shore, the main beaches with public access are Taroona Beach, Hinsby Beach and Dixons Beach. Past Hinsby Beach, the Alum Cliffs form a section of cliffed coast to the neighbouring suburb of Bonnet Hill. Name The name ''Taroona'' is derived from the Mouheneener word for chiton, a marine mollusc found on rocks in the intertidal regions of the Taroona foreshore. History Traditional owners Prior to the British colonisation of Tasmania, the land had been occupied for possibly as long as 35,000 years by the semi-nomadic Mouheneener people, a sub-group of the Nuennone, or "South-East tribe". Mouheneener shell middens can be found scatt ...
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Hobart
Hobart ( ; Nuennonne/ Palawa kani: ''nipaluna'') is the capital and most populous city of the Australian island state of Tasmania. Home to almost half of all Tasmanians, it is the least-populated Australian state capital city, and second-smallest if territories are taken into account, before Darwin, Northern Territory. Hobart is located in Tasmania's south-east on the estuary of the River Derwent, making it the most southern of Australia's capital cities. Its skyline is dominated by the kunanyi/Mount Wellington, and its harbour forms the second-deepest natural port in the world, with much of the city's waterfront consisting of reclaimed land. The metropolitan area is often referred to as Greater Hobart, to differentiate it from the City of Hobart, one of the five local government areas that cover the city. It has a mild maritime climate. The city lies on country which was known by the local Mouheneener people as nipaluna, a name which includes surrounding features such as ...
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Insurance Population
Translocation in wildlife conservation is the capture, transport and release or introduction of species, habitats or other ecological material (such as soil) from one location to another. It contrasts with reintroduction, a term which is generally used to denote the introduction into the wild of species from captive stock. The International Union for the Conservation of Nature (IUCN) catalogues translocation projects for threatened species around the globe. Overview Translocation can be an effective management strategy and important topic in conservation biology, but despite their popularity, translocations are a high‐cost endeavor with a history of failures. It may decrease the risk of extinction by increasing the range of a species, augmenting the numbers in a critical population, or establishing new populations. Translocation may also improve the level of biodiversity in the ecosystem. Translocation may be expensive and is often subject to public scrutiny, particularly w ...
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Quoll
Quolls (; genus ''Dasyurus'') are carnivorous marsupials native to Australia and New Guinea. They are primarily nocturnal and spend most of the day in a den. Of the six species of quoll, four are found in Australia and two in New Guinea. Another two species are known from fossil remains in Pliocene and Pleistocene deposits in Queensland. Genetic evidence indicates that quolls evolved around 15 million years ago in the Miocene, and that the ancestors of the six species had all diverged by around four million years ago. The six species vary in weight and size, from to . They have brown or black fur and pink noses. They are largely solitary, but come together for a few social interactions such as mating which occurs during the winter season. A female gives birth to up to 18 pups, of which only six survive because she only has six teats with which to feed them. They have a life span from 2 to 4 years. Quolls eat smaller mammals, small birds, lizards, and insects. All species have ...
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Tetraploidy
Polyploidy is a condition in which the cells of an organism have more than one pair of ( homologous) chromosomes. Most species whose cells have nuclei (eukaryotes) are diploid, meaning they have two sets of chromosomes, where each set contains one or more chromosomes and comes from each of two parents, resulting in pairs of homologous chromosomes between sets. However, some organisms are polyploid. Polyploidy is especially common in plants. Most eukaryotes have diploid somatic cells, but produce haploid gametes (eggs and sperm) by meiosis. A monoploid has only one set of chromosomes, and the term is usually only applied to cells or organisms that are normally diploid. Males of bees and other Hymenoptera, for example, are monoploid. Unlike animals, plants and multicellular algae have life cycles with two alternating multicellular generations. The gametophyte generation is haploid, and produces gametes by mitosis, the sporophyte generation is diploid and produces spores by meiosi ...
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Australian Broadcasting Corporation
The Australian Broadcasting Corporation (ABC) is the national broadcaster of Australia. It is principally funded by direct grants from the Australian Government and is administered by a government-appointed board. The ABC is a publicly-owned body that is politically independent and fully accountable, with its charter enshrined in legislation, the ''Australian Broadcasting Corporation Act 1983''. ABC Commercial, a profit-making division of the corporation, also helps to generate funding for content provision. The ABC was established as the Australian Broadcasting Commission on 1 July 1932 by an act of federal parliament. It effectively replaced the Australian Broadcasting Company, a private company established in 1924 to provide programming for A-class radio stations. The ABC was given statutory powers that reinforced its independence from the government and enhanced its news-gathering role. Modelled after the British Broadcasting Corporation (BBC), which is funded by a tel ...
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Diploid
Ploidy () is the number of complete sets of chromosomes in a cell, and hence the number of possible alleles for autosomal and pseudoautosomal genes. Sets of chromosomes refer to the number of maternal and paternal chromosome copies, respectively, in each homologous chromosome pair, which chromosomes naturally exist as. Somatic cells, tissues, and individual organisms can be described according to the number of sets of chromosomes present (the "ploidy level"): monoploid (1 set), diploid (2 sets), triploid (3 sets), tetraploid (4 sets), pentaploid (5 sets), hexaploid (6 sets), heptaploid or septaploid (7 sets), etc. The generic term polyploid is often used to describe cells with three or more chromosome sets. Virtually all sexually reproducing organisms are made up of somatic cells that are diploid or greater, but ploidy level may vary widely between different organisms, between different tissues within the same organism, and at different stages in an organism's life cycle. ...
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Tetraploid
Polyploidy is a condition in which the cells of an organism have more than one pair of ( homologous) chromosomes. Most species whose cells have nuclei (eukaryotes) are diploid, meaning they have two sets of chromosomes, where each set contains one or more chromosomes and comes from each of two parents, resulting in pairs of homologous chromosomes between sets. However, some organisms are polyploid. Polyploidy is especially common in plants. Most eukaryotes have diploid somatic cells, but produce haploid gametes (eggs and sperm) by meiosis. A monoploid has only one set of chromosomes, and the term is usually only applied to cells or organisms that are normally diploid. Males of bees and other Hymenoptera, for example, are monoploid. Unlike animals, plants and multicellular algae have life cycles with two alternating multicellular generations. The gametophyte generation is haploid, and produces gametes by mitosis, the sporophyte generation is diploid and produces spores by meio ...
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Myelin Basic Protein
Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction. MBP maintains the correct structure of myelin, interacting with the lipids in the myelin membrane. MBP was initially sequenced in 1971 after isolation from bovine myelin membranes. MBP knockout mice called shiverer mice were subsequently developed and characterized in the early 1980s. ''Shiverer'' mice exhibit decreased amounts of CNS myelination and a progressive disorder characterized by tremors, seizures, and early death. The human gene for MBP is on chromosome 18; the protein localizes to the CNS and to various cells of the hematopoietic lineage. The pool of MBP in the central nervous system is very diverse, with several splice variants being expressed and a large number of po ...
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Transcription (genetics)
Transcription is the process of copying a segment of DNA into RNA. The segments of DNA transcribed into RNA molecules that can encode proteins are said to produce messenger RNA (mRNA). Other segments of DNA are copied into RNA molecules called non-coding RNAs (ncRNAs). mRNA comprises only 1–3% of total RNA samples. Less than 2% of the human genome can be transcribed into mRNA ( Human genome#Coding vs. noncoding DNA), while at least 80% of mammalian genomic DNA can be actively transcribed (in one or more types of cells), with the majority of this 80% considered to be ncRNA. Both DNA and RNA are nucleic acids, which use base pairs of nucleotides as a complementary language. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, antiparallel RNA strand called a primary transcript. Transcription proceeds in the following general steps: # RNA polymerase, together with one or more general transcription factors, binds to promoter ...
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