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Daria Hazuda
Daria J Hazuda is a biochemist known for discovering the first HIV Integrase strand transfer inhibitor, Integrase Strand Transfer Inhibitors (InSTIs) and leading the development of the first HIV integrase inhibitor to gain Food and Drug Administration, FDA approval, Raltegravir, Isentress (raltegravir). Her lab also determined these inhibitors' mechanism of action and ways the virus could develop resistance to them. Hazuda has also performed extensive research and led the development of antivirals for Hepatitis C Virus (HCV) including Elbasvir and Grazoprevir. She currently serves as Vice President for Infectious Diseases Discovery for Merck & Co., Merck and Chief Scientific Officer of their MRL Cambridge Exploratory Science Center. Early life and education Hazuda was raised in Hillsborough Township, New Jersey. Her father was an engineer and her mother worked in the regulatory-compliance division of Janssen Pharmaceutica (now a part of Johnson & Johnson). She graduated in 1977 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biology
Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary information encoded in genes, which can be transmitted to future generations. Another major theme is evolution, which explains the unity and diversity of life. Energy processing is also important to life as it allows organisms to move, grow, and reproduce. Finally, all organisms are able to regulate their own internal environments. Biologists are able to study life at multiple levels of organization, from the molecular biology of a cell to the anatomy and physiology of plants and animals, and evolution of populations.Based on definition from: Hence, there are multiple subdisciplines within biology, each defined by the nature of their research questions and the tools that they use. Like other scientists, biologists use the sc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wu Cheng-wen (biochemist)
Wu Cheng-wen (; born 19 June 1938) is a Taiwanese biochemist. He is the former founding president of National Health Research Institutes in 1996–2005. Wu Was elected as an academician of Taiwan Academia Sinicain 1984. He is a 1988 Guggenheim fellow, as well as a 2011 recipient of the in Life Sciences. Wu was the director of Academia Sinica's Institute of Biomedical Sciences, and served on the Council of the Academia Sinica. He was a professor of pharmacological sciences at Stony Brook University, and lived in Setauket, New York Setauket is a hamlet and census-designated place (CDP) in the Town of Brookhaven, Suffolk County, New York, United States, on the North Shore of Long Island. As of the 2010 United States census The United States census of 2010 was the twe .... Currently he works as a special lecturer at National Yang-Ming University. References 1938 births Affiliated Senior High School of National Taiwan Normal University alumni Living people Taiwan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Georgetown University Alumni
Georgetown University is a private research university located in Washington, D.C. Founded in 1789, Georgetown University is the oldest Catholic and Jesuit institution of higher education in the United States. The school graduates about two thousand undergraduate and postgraduate students annually. There are nine constitutive schools, five of which offer undergraduate degrees and six of which offer graduate degrees, as two schools offer both undergraduate and graduate degrees. Legend Note: Individuals who may belong in multiple sections appear only in one. An empty class year or school/degree box indicates that the information is unknown. ''* Indicates the alumnus or alumna attended but did not graduate (includes years of attendance)'' * Col – Georgetown College :*CAS – former College of Arts & Sciences :*SLL – former School of Languages and Linguistics, now the Faculty of Languages and Linguistics within the College * Dent – School of Dentistry (defunct) * Grad ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calendar year (the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Women Biochemists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society For Microbiology
The American Society for Microbiology (ASM), originally the Society of American Bacteriologists, is a professional organization for scientists who study viruses, bacteria, fungi, algae, and protozoa as well as other aspects of microbiology. It was founded in 1899. The Society publishes a variety of scientific journals, textbooks, and other educational materials related to microbiology and infectious diseases. ASM organizes annual meetings, as well as workshops and professional development opportunities for its members. History ASM was founded in 1899 under the name the "Society of American Bacteriologists." In December 1960, it was renamed the "American Society for Microbiology." Mission ASM's mission is "to promote and advance the microbial sciences." The society seeks to accomplish this mission through: * Publishing highly-cited publications * Running multi-disciplinary meetings * Deploying resources and expertise around the world * Advocating for scientific research * Fost ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ohio State University
The Ohio State University, commonly called Ohio State or OSU, is a public land-grant research university in Columbus, Ohio. A member of the University System of Ohio, it has been ranked by major institutional rankings among the best public universities in the United States. Founded in 1870 as the state's land-grant university and the ninth university in Ohio with the Morrill Act of 1862, Ohio State was originally known as the Ohio Agricultural and Mechanical College and focused on various agricultural and mechanical disciplines, but it developed into a comprehensive university under the direction of then-Governor and later U.S. president Rutherford B. Hayes, and in 1878, the Ohio General Assembly passed a law changing the name to "the Ohio State University" and broadening the scope of the university. Admission standards tightened and became greatly more selective throughout the 2000s and 2010s. Ohio State's political science department and faculty have greatly contri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Integrase
Retroviral integrase (IN) is an enzyme produced by a retrovirus (such as HIV) that integrates—forms covalent links between—its genetic information into that of the host cell it infects. Retroviral INs are not to be confused with phage integrases (recombinases) used in biotechnology, such as λ phage integrase, as discussed in site-specific recombination. The macromolecular complex of an IN macromolecule bound to the ends of the viral DNA ends has been referred to as the '' intasome''; IN is a key component in this and the retroviral pre-integration complex. Structure All retroviral IN proteins contain three canonical domains, connected by flexible linkers: ● an N-terminal HH-CC zinc-binding domain (a three-helical bundle stabilized by coordination of a Zn(II) cation) ● a catalytic core domain (RNaseH fold) ● a C-terminal DNA-binding domain ( SH3 fold). Crystal and NMR structures of the individual domains and 2-domain constructs of integrases ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
AmfAR, The Foundation For AIDS Research
amfAR, the Foundation for AIDS Research, known until 2005 as the American Foundation for AIDS Research, is an international nonprofit organization dedicated to the support of AIDS research, HIV prevention, treatment education, and the advocacy of AIDS-related public policy. AmfAR is a tax-exempt corporation under Internal Revenue Code section 501(c)(3) and operates as an independent nonprofit with worldwide initiatives. amfAR was formed in New York City in September 1985 by Dr. Mathilde Krim, along with physician Dr. Joseph Sonnabend and activist Michael Callen. The organization originally began in April 1983 as the Krim-founded AIDS Medical Foundation (AMF), which sought to lessen the stigma surrounding HIV/AIDS diagnoses, as well as to increase funding to the cause. The name change came as a result of the AMF's merge with the California-based National AIDS Research Foundation, which sought to actively engage in HIV-related drug development. What resulted was a foundation that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Cancer Institute
The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. The NCI conducts and supports research, training, health information dissemination, and other activities related to the causes, prevention, diagnosis, and treatment of cancer; the supportive care of cancer patients and their families; and cancer survivorship. NCI is the oldest and has the largest budget and research program of the 27 institutes and centers of the NIH ($6.9 billion in 2020). It fulfills the majority of its mission via an extramural program that provides grants for cancer research. Additionally, the National Cancer Institute has intramural research programs in Bethesda, Maryland, and at the Frederick National Laboratory for Cancer Research at Fort Detrick in Frederick, Maryland. The NCI receives more than in funding each ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research instit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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