Dan Duchaine
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Dan Duchaine
Daniel Duchaine (1952 – January 12, 2000) was an American bodybuilder. Nicknamed ''the steroid guru'', Duchaine gained worldwide notoriety due to his outspoken opinions on the use of performance-enhancing drugs, and made numerous television appearances discussing the subject on shows such as ''20/20'', ''Geraldo'', and '' 60 Minutes''. ''Steroid Nation'' author and ESPN writer Shaun Assael calls Duchaine "a founding father of the steroid movement." Duchaine and steroids Duchaine began competitive bodybuilding in his home state of Maine in 1977; however, after he had no luck (describing himself as a "miserable bodybuilder"), he began using anabolic steroids that he persuaded his family physician in Portland to prescribe as a training aid. However, after beginning their use he said "I still wasn't very good. Obviously something wasn't working, and the doctors and the pharmacists couldn't really answer my questions. So I started looking into steroids on my own." This was the s ...
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2,4-Dinitrophenol
2,4-Dinitrophenol (2,4-DNP or simply DNP) is an organic compound with the formula HOC6H3(NO2)2. It is a yellow, crystalline solid that has a sweet, musty odor. It sublimates, is volatile with steam, and is soluble in most organic solvents as well as aqueous alkaline solutions. When in a dry form, it is a high explosive and has an instantaneous explosion hazard. It is a precursor to other chemicals and is biochemically active, uncoupling oxidative phosphorylation from the electron transport chain in cells with mitochondria, by allowing protons to pass from the intermembrane space into the mitochondrial matrix. Oxidative phosphorylation is a highly regulated step in aerobic respiration that is inhibited, among other factors, by normal cellular levels of ATP. Uncoupling it results in chemical energy from diet and energy stores such as triglycerides being wasted as heat with minimal regulation, leading to dangerously high body temperatures that may develop into heatstroke. Its use as a ...
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Experimental And Applied Sciences
EAS (formerly Experimental & Applied Sciences) was a distributor of creatine nutritional supplements with approximately 300 staff, annual sales exceeding $300 million, and offices/distributors in 54 countries. History EAS was founded in Pacific Grove, Monterey County, California in 1992 by biochemist Anthony Almada, and businessman Ed Byrd. In 2012, Byrd founded EAB Lab After discovering the possible benefits for Athlete's foot, athletes of creatine monohydrate supplementation, in December 1992 they acquired a kilogram of creatine and began trials. In 1993 they released the first commercially available creatine supplement intended specifically for strength and muscle enhancement under the EAS brand name Phosphagen. The product caught the eye of Bill Phillips, publisher of ''Muscle Media 2000'' (usually referred to as "MM2K"), and he began to write about its benefits in the ''Natural Supplement Review'' and his subscriber-based newsletters. In 1994 he purchased EAS from Al ...
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Methandrostenolone
Metandienone, also known as methandienone or methandrostenolone and sold under the brand name Dianabol (D-Bol) among others, is an androgen and anabolic steroid (AAS) medication which is still quite often used because of its affordability and effectiveness for bulking cycles. It is also used non-medically for physique- and performance-enhancing purposes. It is often taken by mouth. Side effects of metandienone include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire, estrogenic effects like fluid retention and breast enlargement, and liver damage. The drug is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT), and has strong anabolic effects and moderate androgenic effects. It also has moderate estrogenic effects. Metandienone was originally developed in 1955 by Novartis#Ciba-Geigy, CIBA and marketed in Germany and the United States. As the CIBA pro ...
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Nandrolone
Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin). Nandrolone esters are used in the treatment of anemias, cachexia (muscle wasting syndrome), osteoporosis, breast cancer, and for other indications. They are not used by mouth and instead are given by injection into muscle or fat. Side effects of nandrolone esters include symptoms of masculinization like acne, increased hair growth, voice changes, and decreased sexual desire due to its ability to suppress endogenous testosterone synthesis while not being a sufficient androgen itself. They are synthetic androgens and anabolic steroids and hence are agonists of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT). Nandrolone has strong anabolic effects and weak androgenic effects, which giv ...
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Polycystic Kidney Disease
Polycystic kidney disease (PKD or PCKD, also known as polycystic kidney syndrome) is a genetic disorder in which the renal tubules become structurally abnormal, resulting in the development and growth of multiple cysts within the kidney. These cysts may begin to develop in utero, in infancy, in childhood, or in adulthood. Cysts are non-functioning tubules filled with fluid pumped into them, which range in size from microscopic to enormous, crushing adjacent normal tubules and eventually rendering them non-functional as well. PKD is caused by abnormal genes that produce a specific abnormal protein; this protein has an adverse effect on tubule development. PKD is a general term for two types, each having their own pathology and genetic cause: autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD). The abnormal gene exists in all cells in the body; as a result, cysts may occur in the liver, seminal vesicles, and pancreas. This ...
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Carlsbad, California
Carlsbad is a coastal city in the North County region of San Diego County, California, United States. The city is south of downtown Los Angeles and north of downtown San Diego. As of the 2020 census, the population of the city was 114,746. Carlsbad is a popular tourist destination and home to many businesses in the golf industry. History Carlsbad's history began with the Luiseño people (the Spanish name given to them because of their proximity to Mission San Luis Rey), as well as some Kumeyaay in the La Costa area. Nearly every reliable fresh water creek had at least one native village, including one called Palamai. The site is located just south of today's Buena Vista Lagoon. The first European land exploration of Alta California, the Spanish Portolá expedition of 1769, met native villagers while camped on Buena Vista Creek. Another Luiseño villages within today's city of Carlsbad was a village at the mouth of the San Marcos Creek that the Kumeyaay called 'Ajopunq ...
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Bill Phillips (author)
William Nathaniel Phillips (born September 23, 1964) is an American entrepreneur and author. He wrote '' Body for Life: 12 Weeks to Mental and Physical Strength'' with Mike D'Orso. He is also the author of ''Eating for Life'' and the founder and former editor in chief of ''Muscle Media'' magazine and the former CEO of EAS, a performance nutritional supplement company. Other books that Phillips has authored are ''Anabolic Reference Guide,'' ''The Natural Supplement Review,'' and ''Transformation: The Mindset You Need. The Body You Want. The Life You Deserve''. Phillips made a promotional movie called ''Body of Work'' which was filmed in Las Vegas, Nevada and chronicled the first EAS Challenge. Personal life Born in September 1964, Phillips was raised in Golden, Colorado, where he lived with his father Bill (often referred to as BP), mother Suzanne, sister Shelly and brother Shawn. His father, William Phillips Sr., worked for the Coors Brewing Company while taking law classes a ...
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National Collegiate Athletic Association
The National Collegiate Athletic Association (NCAA) is a nonprofit organization that regulates student athletics among about 1,100 schools in the United States, Canada, and Puerto Rico. It also organizes the athletic programs of colleges and universities in the United States and Canada and helps over 500,000 college student athletes who compete annually in college sports. The organization is headquartered in Indianapolis, Indiana. Until 1957, the NCAA was a single division for all schools. That year, the NCAA split into the University Division and the College Division. In August 1973, the current three-division system of Division I, Division II, and Division III was adopted by the NCAA membership in a special convention. Under NCAA rules, Division I and Division II schools can offer scholarships to athletes for playing a sport. Division III schools may not offer any athletic scholarships. Generally, larger schools compete in Division I and smaller schools in II and III. ...
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United States Olympic Committee
The United States Olympic & Paralympic Committee (USOPC) is the National Olympic Committee and the National Paralympic Committee for the United States. It was founded in 1895 as the United States Olympic Committee, and is headquartered in Colorado Springs, Colorado. The USOPC is one of only four NOCs in the world that also serve as the National Paralympic Committee for their country. The USOPC is responsible for supporting, entering and overseeing U.S. teams for the Olympic Games, Paralympic Games, Youth Olympic Games, Pan American Games, and Parapan American Games and serves as the steward of the Olympic and Paralympic Movements in the United States. The Olympic Movement is overseen by the International Olympic Committee (IOC). The IOC is supported by 35 international federations that govern each sport on a global level, National Olympic Committees that oversee Olympic sport as a whole in their respective nations, and national federations that administer each sport at the nat ...
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UCLA
The University of California, Los Angeles (UCLA) is a public land-grant research university in Los Angeles, California. UCLA's academic roots were established in 1881 as a teachers college then known as the southern branch of the California State Normal School (now San José State University). This school was absorbed with the official founding of UCLA as the Southern Branch of the University of California in 1919, making it the second-oldest of the 10-campus University of California system (after UC Berkeley). UCLA offers 337 undergraduate and graduate degree programs in a wide range of disciplines, enrolling about 31,600 undergraduate and 14,300 graduate and professional students. UCLA received 174,914 undergraduate applications for Fall 2022, including transfers, making the school the most applied-to university in the United States. The university is organized into the College of Letters and Science and 12 professional schools. Six of the schools offer undergraduate degre ...
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Don Catlin
Don H. Catlin (born June 4, 1938) is an anti- doping scientist and one of the founders of modern drug-testing in sport. Career Catlin has overseen testing for performance-enhancing drugs at the three most recent Olympics held in the United States since the 1984 Summer Games in Los Angeles, as well as testing for the United States Olympic Committee, the National Collegiate Athletic Association (NCAA), Major League Baseball's minor leagues and the National Football League (NFL). He has also developed drug identification techniques currently in use at the Olympic, professional and collegiate levels. In 1982, Catlin founded the UCLA Olympic Analytical Laboratory, the first anti-doping lab in the United States and now the world's largest testing facility of performance-enhancing drugs. He remained the lab's director for 25 years. Catlin currently serves as president and CEO of the Los Angeles-based NGO Anti-Doping Research, Inc. (ADR). The organization was founded in 2005 to bols ...
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