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Ducas And Kapetanakis Pigmented Purpura
Doucas and Kapetanakis pigmented purpura is a skin condition characterized by scaly and eczematous patches, which also have petechiae and hemosiderin Hemosiderin image of a kidney viewed under a microscope. The brown areas represent hemosiderin Hemosiderin or haemosiderin is an iron-storage complex that is composed of partially digested ferritin and lysosomes. The breakdown of heme gives rise ... staining. It is a lymphocytic capillaritis of unknown cause. Lesions consist of erythematous and purpuric macules which usually begin around the ankles, coalesce, and spread to involve the whole legs, and sometimes the trunk and upper extremities. The lesions are extremely pruritic (itchy) and occasionally lichenified after prolonged scratching. It is also known as "eczematoid purpura" or "eczematoid-like purpura". It was characterized in 1953. See also * Pigmentary purpuric eruptions * List of cutaneous conditions References External links Vascular-related cutaneous ...
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Petechiae
A petechia () is a small red or purple spot (≤4 mm in diameter) that can appear on the skin, conjunctiva, retina, and mucous membranes which is caused by haemorrhage of capillaries. The word is derived from Italian , 'freckle,' of obscure origin. It refers to one of the three descriptive types of hematoma differentiated by size, the other two being ecchymosis (>1cm in diameter) and purpura (4-10mm in diameter). The term is always used in the plural (petechiae), since a single petechia is seldom noticed or significant. Causes Physical trauma The most common cause of petechiae is through physical trauma such as a hard bout of coughing, holding breath, vomiting, or crying, which can result in facial petechiae, especially around the eyes. Such instances are harmless and usually disappear within a few days. * Constriction, asphyxiation – petechiae, especially in the eyes, may also occur when excessive pressure is applied to tissue (e.g., when a tourniquet is applied to an extremity ...
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Hemosiderin
Hemosiderin image of a kidney viewed under a microscope. The brown areas represent hemosiderin Hemosiderin or haemosiderin is an iron-storage complex that is composed of partially digested ferritin and lysosomes. The breakdown of heme gives rise to biliverdin and iron. The body then traps the released iron and stores it as hemosiderin in tissues. Hemosiderin is also generated from the abnormal metabolic pathway of ferritin. It is only found within cells (as opposed to circulating in blood) and appears to be a complex of ferritin, denatured ferritin and other material. The iron within deposits of hemosiderin is very poorly available to supply iron when needed. Hemosiderin can be identified histologically with ''Perls' Prussian blue stain''; iron in hemosiderin turns blue to black when exposed to potassium ferrocyanide. In normal animals, hemosiderin deposits are small and commonly inapparent without special stains. Excessive accumulation of hemosiderin is usually detected within ...
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Capillaritis
Capillaritis is where the capillaries, usually of the legs or lungs, are inflamed, allowing blood cells to pass through. It may occur in the lungs as pulmonary capillaritis, or in the skin Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different de ... as pigmented purpuric dermatosis. Capillaritis usually affects otherwise healthy people. Capillaritis can take many forms but is made up of tiny red or brown dots that may be spread out or in a group forming a red or brown patch on the skin. One variation, Majocchi purpura, forms concentric rings. Capillaritis is a mild condition not requiring treatment. There is no known cure, however capillaritis can disappear within a few weeks, recur from time to time, or persist for years. References {{Cutaneous vasculitis Vascular diseases ...
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Pigmentary Purpuric Eruptions
Pigmented purpuric dermatosis refers to one of the three major classes of skin conditions characterized by purpuric skin eruptions. Pigmented purpuric dermatosis are distinguished from other purpura by size (0.3–1 cm) and are most often seen in the lower extremities. Pigmentary purpuric eruptions may present with one of several clinical patterns. There may be overlapping characteristics among pigmented purpuric dermatosis and between their signs and those of other purpuric eruptions. Examples of the pigmented purpuric dermatosis group include: :* Schamberg's disease :* Majocchi's disease (Purpura annularis telangiectodes) :* Gougerot-Blum syndrome (Pigmented purpuric lichenoid dermatitis) :* Ducas and Kapetanakis pigmented purpura :* Lichen aureus Although vascular damage may be present, it is insufficient for these conditions to be considered forms of vasculitis. A few very small non-blinded studies of treatment with narrow-band ultraviolet light have been reported ...
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List Of Cutaneous Conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against the external environment. The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin.Burns, Tony; ''et al''. (2006) ''Rook's Textbook of Dermatology CD-ROM''. Wiley-Blackwell. . Within the latter type, the hairs occur in structures called pilosebaceous units, each with hair follicle, sebaceous gland, and associated arrector pili muscle. In the embryo, the epidermis, hair, and glands form from the ectoderm, which is chemically influenced by the underlying mesoderm th ...
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