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Dose Response Relationships
Dose or Dosage may refer to: Music * ''Dose'' (Gov't Mule album), 1998 * ''Dose'' (Latin Playboys album) * ''Dosage'' (album), by the band Collective Soul * "Dose" (song), a 2018 song by Ciara * "Dose", song by Filter from the album '' Short Bus'' Science * Dose (biochemistry), a measured quantity of a medicine, nutrient, or pathogen which is delivered as a unit. * Dosage (pharmacology), prescribed regimen of medication administration, including amount, frequency, and duration * Dosage form, a mixture of active and inactive components used to administer a medication * Dosing, feeding chemicals or medicines when used in small quantities * Effective dose (pharmacology), a dose or concentration of a drug that produces a biological response *Absorbed dose, a measure of energy deposited in matter from ionizing radiation *Equivalent dose, a measure of cancer/heritable health risk in tissue from ionizing radiation *Effective dose (radiation), a measure of cancer/heritable health ri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dose (Gov't Mule Album)
''Dose'' is the second studio album by American rock band Gov't Mule Gov't Mule (pronounced "Government Mule") is an American Southern rock jam band, formed in 1994 by guitarist Warren Haynes, bassist Allen Woody (both of The Allman Brothers Band at the time) and drummer Matt Abts (whom Haynes had worked with in .... It was released on February 24, 1998, by Capricorn Records and (on Gramophone record, vinyl) by Evil Teen Records. It was produced, recorded and mixed by Michael Barbiero and is a much darker record than Gov't Mule's self-titled debut album. The songs "Thelonius Beck" and "Birth of the Mule" were tributes to jazz musicians Thelonious Monk and Miles Davis, respectively, whereas the subtitle "Beck" refers to Jeff Beck, who also recorded a song named "Thelonius". Track listing All songs written by Warren Haynes unless otherwise noted. The bonus track appears on the limited edition vinyl version released by Evil Teen Records. It's an acoustic version recorded at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Median Lethal Dose
In toxicology, the median lethal dose, LD50 (abbreviation for " lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 is a toxic unit that measures the lethal dose of a given substance. The value of LD50 for a substance is the dose required to kill half the members of a tested population after a specified test duration. LD50 figures are frequently used as a general indicator of a substance's acute toxicity. A lower LD50 is indicative of higher toxicity. The term LD50 is generally attributed to John William Trevan. The test was created by J. W. Trevan in 1927. The term semilethal dose is occasionally used in the same sense, in particular with translations of foreign language text, but can also refer to a sublethal dose. LD50 is usually determined by tests on animals such as laboratory mice. In 2011, the U.S. Food and Drug Administration approved alternative methods to LD50 for testing the cosmetic drug botox without animal tests. Conventions The LD50 is usually expr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Double Dose (other)
Double Dose is a common expression generally meaning double that of the typical amount. It may also refer to: * ''Double Dose'' (Hot Tuna album), 1978 * ''Double Dose'' (Tela album), 2002 * '' Double Dose: Ultimate Hits'', a 2011 album by Poison * "Double Dose" (''Superman: The Animated Series''), a 1997 episode See also * '' A Double Dose'', a 2004 album by Great White * Dose (other) {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gerd Dose
Gerd Dose (born 9 October 1942 in Halstenbek, died 16 July 2010 in Großensee (Holstein)) was a professor of English literature and culture at the University of Hamburg from 1985 to 2007. His main research interests were medieval English literature, English comic literature, cultural studies, Australian studies, and the reception of war and the military in English comic literature. Also, research on constancy and variation in behaviour in Shakespeare's tragedy ''Coriolanus ''Coriolanus'' ( or ) is a tragedy by William Shakespeare, believed to have been written between 1605 and 1608. The play is based on the life of the legendary Roman leader Gnaeus Marcius Coriolanus. Shakespeare worked on it during the same ...''. He set up "modern English language literatures" as an area of teaching and research. Major publications * Adel und Gemeinwesen (Bern / Frankfurt a.M. / Las Vegas, 1977), 234 S. * "Agatha Christie und nicht P. G. Wodehouse", in Anglistik und Englischunterr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Döse
Döse (Low German: ''Döös'') the northernmost town in Lower Saxony, Germany at the point where the River Elbe flows into the North Sea. It is a borough of the city Cuxhaven and a popular seaside resort. Döse is located west of Grimmershörn in the borough of Cuxhaven and is one of the tourist centres of the region of Cuxland. History Until 1937 Döse, like Cuxhaven, was part of the Land of Hamburg. Gallery File:Cuxhaven-St Gertrud-Daemmerung-Dez2007.jpg, The Evangelical Lutheran "Döser Kirche": Döse Church of St. Gertrud's File:Cuxhaven-Doese-Beach.JL.jpg, Beach at Döse File:Cuxhaven 07-2016 photo23 Kugelbake.jpg, The Kugelbake The Kugelbake (English: Ball Beacon) is a historic day beacon in the city of Cuxhaven, Germany, at the northernmost point of Lower Saxony, where the River Elbe flows into the North Sea. In the Low German dialect of the Middle Ages, the term ''bake ..., marking the northernmost point of Lower Saxony References Former municipalities in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dose (magazine)
''Dose'' is a daily Canadian news website and former daily print magazine. It was a mixture of standalone features and coverage of daily news, sometimes from an irreverent perspective. Each daily issue had a theme, and the top margins of every page usually included trivia items related to the theme. History ''Dose'' magazine was launched on April 4, 2005, and was distributed in five major Canadian cities: Toronto, Vancouver, Calgary, Edmonton, and Ottawa. Different news articles from the five cities are still featured on the website. The magazine hoped to earn revenue through advertising and selling mobile content (via the website) and was aimed at the lucrative demographic of 18- to 34-year-olds. The website targets this market too. ''Dose'' was published by Noah Godfrey, son of CanWest board of directors member Paul Godfrey. The content team included editor-in-chief, Pema Hegan and creative director, Jaspal Riyait. The magazine was the product of Canwest Mediaworks Publications ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dosa (food)
A dosa, dosai or dosay is a thin, savoury crepe in South Indian cuisine, Indian cuisine made from a fermentation (food), fermented batter (cooking), batter of ground Vigna mungo, black gram and rice. Dosas are served hot, often with chutney and Sambar (dish), sambar. History The dosa originated in South India, but its precise geographical origins are unknown. According to food historian K. T. Achaya, references in the Sangam literature suggest that dosa was already in use in the Tamilagam, ancient Tamil country around the first century CE. However, according to historian P. Thankappan Nair, dosa originated in the town of Udupi in Karnataka. Achaya states that the earliest written mention of dosa appears in the eighth-century literature of present-day Tamil Nadu, while the earliest mention of dosaë in Tulu literature appears a century later. In popular tradition outside of Southern India, the origin of the dosa is linked to Udupi, probably because of the dish's association w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endorphins
Endorphins (contracted from endogenous morphine) are peptides produced in the brain that block the perception of pain and increase feelings of wellbeing. They are produced and stored in the pituitary gland of the brain. Endorphins are endogenous painkillers often produced in the brain and adrenal medulla during physical exercise or orgasm and inhibit pain, muscle cramps, and relieve stress. History Opioid peptides in the brain were first discovered in 1973 by investigators at the University of Aberdeen, John Hughes and Hans Kosterlitz. They isolated "enkephalins" (from the Greek ) from pig brain, identified as Met-enkephalin and Leu-enkephalin. This came after the discovery of a receptor that was proposed to produce the pain-relieving analgesic effects of morphine and other opioids, which led Kosterlitz and Hughes to their discovery of the endogenous opioid ligands. Research during this time was focused on the search for a painkiller that did not have the addictive charac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serotonin
Serotonin (), also known as 5-hydroxytryptamine (5-HT), is a monoamine neurotransmitter with a wide range of functions in both the central nervous system (CNS) and also peripheral tissues. It is involved in mood, cognition, reward, learning, memory, and physiological processes such as vomiting and vasoconstriction. In the CNS, serotonin regulates mood, appetite, and sleep. Most of the body's serotonin—about 90%—is synthesized in the gastrointestinal tract by enterochromaffin cells, where it regulates intestinal movements. It is also produced in smaller amounts in the brainstem's raphe nuclei, the skin's Merkel cells, pulmonary neuroendocrine cells, and taste receptor cells of the tongue. Once secreted, serotonin is taken up by platelets in the blood, which release it during clotting to promote vasoconstriction and platelet aggregation. Around 8% of the body's serotonin is stored in platelets, and 1–2% is found in the CNS. Serotonin acts as both a vasoconstrictor and vas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxytocin
Oxytocin is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. Present in animals since early stages of evolution, in humans it plays roles in behavior that include Human bonding, social bonding, love, reproduction, childbirth, and the Postpartum period, period after childbirth. Oxytocin is released into the bloodstream as a hormone in response to Human sexual activity, sexual activity and during childbirth. It is also available in Oxytocin (medication), pharmaceutical form. In either form, oxytocin stimulates uterine contractions to speed up the process of childbirth. In its natural form, it also plays a role in maternal bonding and lactation, milk production. Production and secretion of oxytocin is controlled by a positive feedback mechanism, where its initial release stimulates production and release of further oxytocin. For example, when oxytocin is released during a contraction of the uterus at the start of c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dopamine
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic chemical of the catecholamine and phenethylamine families. It is an amine synthesized by removing a carboxyl group from a molecule of its precursor chemical, L-DOPA, which is synthesized in the brain and kidneys. Dopamine is also synthesized in plants and most animals. In the brain, dopamine functions as a neurotransmitter—a chemical released by neurons (nerve cells) to send signals to other nerve cells. The brain includes several distinct dopamine pathways, one of which plays a major role in the motivational component of reward-motivated behavior. The anticipation of most types of rewards increases the level of dopamine in the brain, and many addictive drugs increase dopamine release or block its reuptake into neurons following release. Other brain dopamine pathways are involved in motor control and in controllin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Effective Dose (radiation)
Effective dose is a dose quantity in the International Commission on Radiological Protection (ICRP) system of radiological protection.ICRP publication, 103 para 103 It is the tissue-weighted sum of the equivalent doses in all specified tissues and organs of the human body. It represents the stochastic health risk to the whole body, which is the ''probability'' of cancer induction and genetic effects, of low levels of ionizing radiation. It takes into account the type of radiation and the nature of each organ or tissue being irradiated, and enables summation of organ doses due to varying levels and types of radiation, both internal and external, to produce an overall calculated effective dose. The SI unit for effective dose is the sievert (Sv) which corresponds to a 5.5% chance of developing cancer. The effective dose is not intended as a measure of ''deterministic'' health effects, which is the ''severity'' of acute tissue damage that is certain to happen, that is measured by the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
