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Dobrava-Belgrade Orthohantavirus
''Dobrava-Belgrade orthohantavirus'' (DOBV), also known as Dobrava virus, is an enveloped, single-stranded, negative-sense RNA virus species of Old World ''Orthohantavirus''. It is one of several species of Hantavirus that is the causative agent of severe Hantavirus hemorrhagic fever with renal syndrome. It was first isolated in 1985 from a yellow-necked mouse (''Apodemus flavicollis'') found in the village of Dobrava, southeastern Slovenia. It was subsequently isolated in striped field mice in Russia and other parts of Eastern Europe. It has also been found in Germany but the reservoir host there is unknown. Phylogeny Four genotypes are described: * Dobrava, observed mostly in southeastern Europe * Kurkino, observed throughout northern and eastern Europe * Saaremaa, observed in Estonia and Slovakia * Sochi, observed in the Black Sea coast region of Russia Disease Clinical presentation varies between the four genotypes. Dobrava is the most virulent, with a case-fatality rate (C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Saaremaa Virus
Saaremaa virus is a single-stranded, negative-sense, RNA virus ''Orthohantavirus'' that causes a milder form of Hantavirus hemorrhagic fever with renal syndrome. It is a member virus of ''Dobrava-Belgrade orthohantavirus''. It was first isolated from a striped field mouse in Slovakia.Plyusnin, Alexander, Vaheri, Antti. Saaremaa Hantavirus Should Not Be Confused with Its Dangerous Relative, Dobrava Virus J. Clin. Microbiol. April 2006 vol. 44 no. 4 1608–1611 References External links Sloan Science and Film / Short Films / Muerto Canyonby Jen Peel 29 minutes by Brian Hjelle, M.D., Department of Pathology, School of Medicine, University of New Mexico Virus Pathogen Database and Analysis Resource (ViPR): Bunyaviridae Viral diseases Hantaviridae Hemorrhagic fevers Rodent-carried diseases {{Virus-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Black Sea Field Mouse
The Black Sea field mouse (''Apodemus ponticus'') is a species of rodent in the family Muridae. It is found in Armenia, Azerbaijan, Georgia, possibly Iran, Iraq, Russian Federation, and Turkey Turkey ( tr, Türkiye ), officially the Republic of Türkiye ( tr, Türkiye Cumhuriyeti, links=no ), is a transcontinental country located mainly on the Anatolian Peninsula in Western Asia, with a small portion on the Balkan Peninsula in .... References * Apodemus Mammals of West Asia Mammals of Azerbaijan Mammals of Russia Mammals described in 1936 Taxonomy articles created by Polbot {{Russia-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hantaviridae
''Hantaviridae'' is a family of viruses in the order ''Bunyavirales''. It is named for the Hantan River area in South Korea where an early outbreak of one of its species was observed. Taxonomy * '' Actantavirinae'' ** '' Actinovirus'' * '' Agantavirinae'' ** '' Agnathovirus'' * '' Mammantavirinae'' ** '' Loanvirus'' ** '' Mobatvirus'' ** ''Orthohantavirus ''Orthohantavirus'' is a genus of single-stranded, enveloped, negative-sense RNA viruses in the family '' Hantaviridae'' within the order ''Bunyavirales''. Members of this genus may be called orthohantaviruses or simply hantaviruses. Orthohantav ...'' ** '' Thottimvirus'' * '' Repantavirinae'' ** '' Reptillovirus'' References {{Taxonbar, from=Q29001075 Virus families Bunyavirales ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Viral Diseases
Viral means "relating to viruses" (small infectious agents). Viral may also refer to: Viral behavior, or virality Memetic behavior likened that of a virus, for example: * Viral marketing, the use of existing social networks to spread a marketing message * Viral phenomenon, relating to contagion theory or the "virality" of network culture, such as a meme * Viral video, a video that quickly attains a high popularity Titled works * ''Viral'' (2016 American film), a 2016 American science fiction horror drama * ''Viral'' (2016 Hindi film), an Indian Bollywood film based on social media * ''Viral'' (web series), a 2014 Brazilian comedy web series * '' V/H/S: Viral'', an American anthology horror film * '' Viral: The Search for the Origin of COVID-19'', a book by Alina Chand and Matt Ridley See also * ''Virals'', a novel series by Kathy Reichs * Virulence Virulence is a pathogen's or microorganism's ability to cause damage to a host. In most, especially in animal system ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1993 Four Corners Hantavirus Outbreak
The 1993 Four Corners hantavirus outbreak was an outbreak of hantavirus that caused the first known human cases of hantavirus disease in the United States. It occurred within the Four Corners region – the geographic intersection of the U.S. states of Utah, Colorado, New Mexico, and Arizona – of the Southwestern United States in mid-1993. This region is largely occupied by Native American tribal lands, including the Hopi, Ute, Zuni, and Navajo reservations, from which many of the cases were reported. The virus killed 13 people — half of those it infected, for a mortality rate of 50%. The cause of the outbreak was found to be a previously unknown species of hantavirus, which was responsible for a new form of illness known as hantavirus pulmonary syndrome or HPS. The virus is carried by deer mice. Originally referred to as "Four Corners virus", "Muerto Canyon virus", and "Convict Creek virus", it was later named Sin Nombre virus. Transmission to humans was found to have ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sweating Sickness
Sweating sickness, also known as the sweats, English sweating sickness, English sweat or ''sudor anglicus'' in Latin, was a mysterious and contagious disease that struck England and later continental Europe in a series of epidemics beginning in 1485. The last outbreak occurred in 1551, after which the disease apparently vanished. The onset of symptoms was sudden, with death often occurring within hours. Sweating sickness epidemics were unique compared with other disease outbreaks of the time: whereas other epidemics were typically urban and long-lasting, cases of sweating sickness spiked and receded very quickly, and heavily affected rural populations. Its cause remains unknown, although it has been suggested that an unknown species of hantavirus was responsible. Signs and symptoms John Caius was a physician in Shrewsbury in 1551, when an outbreak occurred, and he described the symptoms and signs of the disease in ''A Boke or Counseill Against the Disease Commonly Called the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Cutaneous Conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against the external environment. The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin.Burns, Tony; ''et al''. (2006) ''Rook's Textbook of Dermatology CD-ROM''. Wiley-Blackwell. . Within the latter type, the hairs occur in structures called pilosebaceous units, each with hair follicle, sebaceous gland, and associated arrector pili muscle. In the embryo, the epidermis, hair, and glands form from the ectoderm, which is chemically influenced by the underlying mesoderm th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Conjunctival Suffusion
Conjunctival suffusion is an eye finding occurring early in leptospirosis, which is caused by ''Leptospira interrogans''. Conjunctival suffusion is characterized by redness of the conjunctiva that resembles conjunctivitis, but it does not involve inflammatory exudates. Swelling of the conjunctiva (chemosis) is seen along the corners of the eye (palpebral fissures). About 30 percent of people with leptospirosis (also known as Weil's disease) develop conjunctival suffusion. When it does occur, it develops towards the end of the early phase of the illness. Even in severe cases, the suffusion occurs in the first phase of the illness. Conjunctival suffusion may also occur in patients with a Hantavirus ''Orthohantavirus'' is a genus of single-stranded, enveloped, negative-sense RNA viruses in the family '' Hantaviridae'' within the order ''Bunyavirales''. Members of this genus may be called orthohantaviruses or simply hantaviruses. Orthohantav ... infection. In a 1994 study o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sangassou Virus
''Sangassou orthohantavirus'' (SANGV) is single-stranded, negative-sense RNA virus species of the genus ''Orthohantavirus'' in the ''Bunyavirales'' order. It was first isolated in an African wood mouse ('' Hylomyscus simus'') in the forest in Guinea, West Africa in 2010. It is named for the village near where the mouse was trapped. It is the first indigenous Murinae-associated African hantavirus to be discovered. Genome The virus genome consists of three segments of negative-stranded RNA; the large (L) segment encodes the viral RNA-dependent RNA polymerase, the medium (M) segment encodes the envelope glycoproteins Gn and Gc (cotranslationally cleaved from a glycoprotein precursor), and the small (S) segment encodes the nucleocapsid (N) protein. Renal syndrome In rodents, hantavirus produces a chronic infection with no adverse sequelae. In humans, hantavirus produces two major clinical syndromes: hemorrhagic fever or pulmonary syndrome. European, Asian, and African rodent-b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hantavirus Vaccine
Hantavirus vaccine is a vaccine that protects in humans against hantavirus infections causing hantavirus hemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome Hantavirus pulmonary syndrome (HPS) is one of two potentially fatal syndromes of zoonotic origin caused by species of hantavirus. These include Black Creek Canal virus (BCCV), New York orthohantavirus (NYV), Monongahela virus (MGLV), ''Sin Nomb ... (HPS). The vaccine is considered important as acute hantavirus infections are responsible for significant morbidity and mortality worldwide. It is estimated that about 1.5 million cases and 46,000 deaths occurred in China from 1950 to 2007. The number of cases is estimated at 32,000 in Finland from 2005 to 2010 and 90,000 in Russia from 1996 to 2006. The first hantavirus vaccine was developed in 1990 initially for use against Hantaan River virus which causes one of the most severe forms of HFRS. It is estimated that about two million doses of rodent brai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Striped Field Mouse
The striped field mouse (''Apodemus agrarius'') is a rodent in the family Muridae. The range of this species stretches from Eastern Europe to Eastern Asia. Synonyms Accepted synonyms include ''Apodemus albostriatus'' (Bechstein, 1801), ''Apodemus caucasicus'' (Kuznetzov, 1944), ''Apodemus chejuensis'' (Johnson and Jones, 1955), ''Apodemus coreae'' (Thomas, 1908), ''Apodemus gloveri'' (Kuroda, 1939), ''Apodemus harti'' (Thomas, 1898), ''Apodemus henrici'' (Lehmann, 1970), ''Apodemus insulaemus'' (Tokuda, 1939 and 1941), ''Apodemus istrianus'' (Kryštufek, 1985), ''Apodemus kahmanni'' (Malec and Storch, 1963), '' Apodemus karelicus'' (Ehrström, 1914), ''Apodemus maculatus'' (Bechstein, 1801), ''Apodemus mantchuricus'' (Thomas, 1898), ''Apodemus nicolskii'' (Charlemagne, 1933), ''Apodemus nikolskii'' (Migouline, 1927), ''Apodemus ningpoensis'' (Swinhoe, 1870), ''Apodemus ognevi'' (Johansen, 1923), ''Apodemus pallescens'' (Johnson and Jones, 1955), ''Apodemus pallidior'' (Thomas, 1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Single-stranded
When referring to DNA transcription, the coding strand (or informational strand) is the DNA strand whose base sequence is identical to the base sequence of the RNA transcript produced (although with thymine replaced by uracil). It is this strand which contains codons, while the non-coding strand contains anticodons. During transcription, RNA Pol II binds to the non-coding template strand, reads the anti-codons, and transcribes their sequence to synthesize an RNA transcript with complementary bases. By convention, the coding strand is the strand used when displaying a DNA sequence. It is presented in the 5' to 3' direction. Wherever a gene exists on a DNA molecule, one strand is the coding strand (or sense strand), and the other is the noncoding strand (also called the antisense strand, anticoding strand, template strand or transcribed strand). Strands in transcription bubble During transcription, RNA polymerase unwinds a short section of the DNA double helix near the start of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
