Diffeomorphometry
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Diffeomorphometry
Diffeomorphometry is the metric study of imagery, shape and form in the discipline of computational anatomy (CA) in medical imaging. The study of images in computational anatomy rely on high-dimensional diffeomorphism groups \varphi \in \operatorname_V which generate orbits of the form \mathcal \doteq \ , in which images I \in \mathcal can be dense scalar magnetic resonance or computed axial tomography images. For deformable shapes these are the collection of manifolds \mathcal \doteq \ , points, curves and surfaces. The diffeomorphisms move the images and shapes through the orbit according to (\varphi,I)\mapsto \varphi \cdot I which are defined as the group actions of computational anatomy. The orbit of shapes and forms is made into a metric space by inducing a metric on the group of diffeomorphisms. The study of metrics on groups of diffeomorphisms and the study of metrics between manifolds and surfaces has been an area of significant investigation. In Compu ...
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Computational Anatomy
Computational anatomy is an interdisciplinary field of biology focused on quantitative investigation and modelling of anatomical shapes variability. It involves the development and application of mathematical, statistical and data-analytical methods for modelling and simulation of biological structures. The field is broadly defined and includes foundations in anatomy, applied mathematics and pure mathematics, machine learning, computational mechanics, computational science, biological imaging, neuroscience, physics, probability, and statistics; it also has strong connections with fluid mechanics and geometric mechanics. Additionally, it complements newer, interdisciplinary fields like bioinformatics and neuroinformatics in the sense that its interpretation uses metadata derived from the original sensor imaging modalities (of which magnetic resonance imaging is one example). It focuses on the anatomical structures being imaged, rather than the medical imaging devices. It is similar i ...
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Riemannian Metric And Lie-Bracket Interpretation Of The Euler Equation On Geodesics
Computational anatomy (CA) is the study of shape and form in medical imaging. The study of deformable shapes in CA rely on high-dimensional diffeomorphism groups \operatorname_V which generate orbits of the form \mathcal \doteq \ . In CA, this orbit is in general considered a smooth Riemannian manifold since at every point of the manifold m \in \mathcal there is an inner product inducing the norm \, \cdot \, _m on the tangent space that varies smoothly from point to point in the manifold of shapes m \in \mathcal . This is generated by viewing the group of diffeomorphisms \varphi \in \operatorname_V as a Riemannian manifold with \, \cdot \, _\varphi , associated to the tangent space at \varphi \in\operatorname_V . This induces the norm and metric on the orbit m \in \mathcal under the action from the group of diffeomorphisms. The diffeomorphisms group generated as Lagrangian and Eulerian flows The diffeomorphisms in computational anatomy are generated to satis ...
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Diffeomorphism
In mathematics, a diffeomorphism is an isomorphism of differentiable manifolds. It is an invertible function that maps one differentiable manifold to another such that both the function and its inverse are continuously differentiable. Definition Given two differentiable manifolds M and N, a Differentiable manifold#Differentiability of mappings between manifolds, continuously differentiable map f \colon M \rightarrow N is a diffeomorphism if it is a bijection and its inverse f^ \colon N \rightarrow M is differentiable as well. If these functions are r times continuously differentiable, f is called a C^r-diffeomorphism. Two manifolds M and N are diffeomorphic (usually denoted M \simeq N) if there is a diffeomorphism f from M to N. Two C^r-differentiable manifolds are C^r-diffeomorphic if there is an r times continuously differentiable bijective map between them whose inverse is also r times continuously differentiable. Diffeomorphisms of subsets of manifolds Given a ...
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Group Actions In Computational Anatomy
Group actions are central to Riemannian geometry and defining orbits (control theory). The orbits of computational anatomy consist of anatomical shapes and medical images; the anatomical shapes are submanifolds of differential geometry consisting of points, curves, surfaces and subvolumes,. This generalized the ideas of the more familiar orbits of linear algebra which are linear vector spaces. Medical images are scalar and tensor images from medical imaging. The group actions are used to define models of human shape which accommodate variation. These orbits are deformable templates as originally formulated more abstractly in pattern theory. The orbit model of computational anatomy The central model of human anatomy in computational anatomy is a Groups and group action, a classic formulation from differential geometry. The orbit is called the space of shapes and forms. The space of shapes are denoted m \in \mathcal , with the group (\mathcal, \circ ) with law of compositi ...
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Vector Space
In mathematics and physics, a vector space (also called a linear space) is a set (mathematics), set whose elements, often called vector (mathematics and physics), ''vectors'', can be added together and multiplied ("scaled") by numbers called scalar (mathematics), ''scalars''. The operations of vector addition and scalar multiplication must satisfy certain requirements, called ''vector axioms''. Real vector spaces and complex vector spaces are kinds of vector spaces based on different kinds of scalars: real numbers and complex numbers. Scalars can also be, more generally, elements of any field (mathematics), field. Vector spaces generalize Euclidean vectors, which allow modeling of Physical quantity, physical quantities (such as forces and velocity) that have not only a Magnitude (mathematics), magnitude, but also a Orientation (geometry), direction. The concept of vector spaces is fundamental for linear algebra, together with the concept of matrix (mathematics), matrices, which ...
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Dynamical System
In mathematics, a dynamical system is a system in which a Function (mathematics), function describes the time dependence of a Point (geometry), point in an ambient space, such as in a parametric curve. Examples include the mathematical models that describe the swinging of a clock pendulum, fluid dynamics, the flow of water in a pipe, the Brownian motion, random motion of particles in the air, and population dynamics, the number of fish each springtime in a lake. The most general definition unifies several concepts in mathematics such as ordinary differential equations and ergodic theory by allowing different choices of the space and how time is measured. Time can be measured by integers, by real number, real or complex numbers or can be a more general algebraic object, losing the memory of its physical origin, and the space may be a manifold or simply a Set (mathematics), set, without the need of a Differentiability, smooth space-time structure defined on it. At any given time, ...
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Green's Function For The Three-variable Laplace Equation
In physics, the Green's function (or fundamental solution) for the Laplacian (or Laplace operator) in three variables is used to describe the response of a particular type of physical system to a point source. In particular, this Green's function arises in systems that can be described by Poisson's equation, a partial differential equation (PDE) of the form \nabla^2 u(\mathbf) = f(\mathbf) where \nabla^2 is the Laplace operator in \mathbb^3, f(\mathbf) is the source term of the system, and u(\mathbf) is the solution to the equation. Because \nabla^2 is a linear differential operator, the solution u(\mathbf) to a general system of this type can be written as an integral over a distribution of source given by f(\mathbf): u(\mathbf) = \int G(\mathbf,\mathbf)f(\mathbf)d\mathbf' where the Green's function for Laplacian in three variables G(\mathbf,\mathbf) describes the response of the system at the point \mathbf to a point source located at \mathbf: \nabla^2 G(\mathbf,\mathbf) = \de ...
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Sobolev Embedding
In mathematics, there is in mathematical analysis a class of Sobolev inequalities, relating norms including those of Sobolev spaces. These are used to prove the Sobolev embedding theorem, giving inclusions between certain Sobolev spaces, and the Rellich–Kondrachov theorem showing that under slightly stronger conditions some Sobolev spaces are compactly embedded in others. They are named after Sergei Lvovich Sobolev. Sobolev embedding theorem Let denote the Sobolev space consisting of all real-valued functions on whose weak derivatives up to order are functions in . Here is a non-negative integer and . The first part of the Sobolev embedding theorem states that if , and are two real numbers such that :\frac-\frac = \frac -\frac, (given n, p, k and \ell this is satisfied for some q \in [1, \infty) provided (k- \ell) p n, the embedding criterion will hold with r=0 and some positive value of \alpha. That is, for a function f on \mathbb R^n, if f has k derivatives in L^ ...
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Green's Function
In mathematics, a Green's function (or Green function) is the impulse response of an inhomogeneous linear differential operator defined on a domain with specified initial conditions or boundary conditions. This means that if L is a linear differential operator, then * the Green's function G is the solution of the equation where \delta is Dirac's delta function; * the solution of the initial-value problem L y = f is the convolution Through the superposition principle, given a linear ordinary differential equation (ODE), one can first solve for each , and realizing that, since the source is a sum of delta functions, the solution is a sum of Green's functions as well, by linearity of . Green's functions are named after the British mathematician George Green, who first developed the concept in the 1820s. In the modern study of linear partial differential equations, Green's functions are studied largely from the point of view of fundamental solutions instead. Under many ...
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