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Dick Haugland
Richard Paul Haugland (July 17, 1943 – October 5, 2016) was an American scientist noted for his work in researching and commercializing fluorescent dyes.C. D. Geddes and J. R. Lakowicz (2003) ''Who's Who in Fluorescence'', Springer. He completed his PhD at Stanford in 1970 under Lubert Stryer, showing in a now widely cited and classic paper that Förster resonance energy transfer (FRET) can be used as a "spectroscopic ruler" to measure distances in macromolecules. Haugland founded Molecular Probes in 1975 and continued as its president after the corporation was bought by Invitrogen in 2003.The Business Information Agency Corp. International (2008) ''USA Major Manufacturers'' 8th ed., pp. 445 He is the original author of the authoritative volume on molecular probes, ''The Molecular Probes Handbook'',https://www.thermofisher.com/th/en/home/references/molecular-probes-the-handbook.html now in its 11th edition. Personal Dick Haugland was born in Huron, South Dakota. His pare ...
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Huron, South Dakota
Huron is a city in Beadle County, South Dakota, United States. It is the county seat of Beadle County. The '' Huron Daily Plainsman'', also referred to as the ''Plainsman'', is the newspaper. The first settlement at Huron was made in 1880. The city was named after the Huron Indians. It is currently the eighth largest city in South Dakota, but it once was the fourth. In recent years, Huron's population has once again started to grow after nearly 20 years of stagnation. A welcoming immigration policy coupled with an economic revival in the area has sparked development. A Walmart Supercenter opened in the mid 2000s. Since Walmart's opening more commercial and residential development has occurred with the completion of a new Runnings store (retailer specializing in farm and fleet products), and many new apartments, twin homes and houses. The greater Huron area is home to approximately 30,000 people. The population within the city limits was 14,263 at the 2020 census. Huron was once ...
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Baraga, Michigan
Baraga ( ) is a village in Baraga County in the U.S. state of Michigan. The population was 1,883 at the 2020 census. The village is named after Bishop Frederic Baraga. The village is located in Baraga Township on the Keweenaw Bay on Lake Superior at the junction of US 41 and M-38. It is entirely within the boundaries of the Keweenaw Bay Indian Reservation. The Baraga ZIP code 49908 also serves areas of northern and northwestern Baraga Township. History Baraga began with the establishment of the Holy Name Mission at this site by Rev. Frederic Baraga in 1843. The post office opened with the name ''Bristol'' on June 29, 1869 and changed to Baraga on May 11, 1870. In 1993, the Baraga Correctional Facility was opened in the town. Geography According to the United States Census Bureau, the village has a total area of , of which is land and is water. Demographics 2020 census As of the census of 2020, the population was 1,883. The population density was . There were 617 hou ...
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Carlsbad, California
Carlsbad is a coastal city in the North County region of San Diego County, California, United States. The city is south of downtown Los Angeles and north of downtown San Diego. As of the 2020 census, the population of the city was 114,746. Carlsbad is a popular tourist destination and home to many businesses in the golf industry. History Carlsbad's history began with the Luiseño people (the Spanish name given to them because of their proximity to Mission San Luis Rey), as well as some Kumeyaay in the La Costa area. Nearly every reliable fresh water creek had at least one native village, including one called Palamai. The site is located just south of today's Buena Vista Lagoon. The first European land exploration of Alta California, the Spanish Portolá expedition of 1769, met native villagers while camped on Buena Vista Creek. Another Luiseño villages within today's city of Carlsbad was a village at the mouth of the San Marcos Creek that the Kumeyaay called 'Ajopunq ...
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Junction City, Oregon
Junction City is a city in Lane County, Oregon, United States. As of the 2020 United States Census, it has a population of 6,747. The Junction City area is notable for its Scandinavian heritage, with the city's Scandinavian Festival attracting over 100,000 visitors annually. Junction City was previously a center of recreational vehicle manufacturing. History The city was incorporated in 1872. Junction City was named by railroad magnate Ben Holladay, who decided that it would be where the rail line on the east side of the Willamette Valley would meet the rail line on the west side. The westside line, however, was not built according to plan and the rail junction never materialized. Junction City later became the meeting point of the east and west branches of U.S. Route 99 (which divide in Portland). In 1902, real estate developer A.C. Nielsen subdivided 1,600 acres of farmland near Junction City into small farms and advertised them in a Danish-language newspaper in Iowa ...
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Plano, Texas
Plano ( ) is a city in Collin County, Texas, Collin County and Denton County, Texas, United States. It had a population of 285,494 at the 2020 United States census, 2020 census. It is a principal city of the Dallas–Fort Worth metroplex. History European settlers came to the area near present-day Plano in the early 1840s. Facilities such as a sawmill, a gristmill, and a store soon brought more people to the area. A mail service was established, and after rejecting several names for the nascent town (including naming it in honor of then-President Millard Fillmore), residents suggested the name ''Plano'' (from the Spanish word for "flat") in reference to the local terrain, unvaried and devoid of any trees. The post office accepted the name. In 1872, the completion of the List of Texas railroads, Houston and Central Texas Railway helped Plano grow, and it was incorporated in 1873. By 1874, the population was over 500. In 1881, a fire raged through the business district, destro ...
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Roseville, Minnesota
Roseville is a city in Ramsey County, Minnesota, United States. It is one of two Minneapolis-Saint Paul, Twin Cities suburbs that are adjacent to both Saint Paul and Minneapolis (the other is Lauderdale, Minnesota, Lauderdale). The land comprising Falcon Heights, Minnesota, Falcon Heights, Lauderdale, and southern Roseville was unincorporated area, unincorporated until Roseville incorporated in 1948 and Falcon Heights and Lauderdale incorporated in 1949. History Roseville's land was originally settled by the Santee Sioux, Dakota and Ojibwe peoples. The first white settlers came in 1843, and the Native Americans in the United States, Native Americans left the area by 1862. Rose Township was established in 1858; it was named after one of the first settlers, Isaac Rose. The township included the areas now known as Roseville, Lauderdale, and Falcon Heights, as well as parts of present-day Saint Paul, Minnesota, Saint Paul and Minneapolis, Minnesota, Minneapolis. The area saw rapid g ...
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Eugene, Oregon
Eugene ( ) is a city in the U.S. state of Oregon. It is located at the southern end of the Willamette Valley, near the confluence of the McKenzie and Willamette rivers, about east of the Oregon Coast. As of the 2020 United States Census, Eugene had a population of 176,654 and covers city area of 44.21 sq mi (114.50 sq km). Eugene is the seat of Lane County and the state's second largest city after Portland. The Eugene-Springfield metropolitan statistical area is the 146th largest in the United States and the third largest in the state, behind those of Portland and Salem. In 2022, Eugene's population was estimated to have reached 179,887. Eugene is home to the University of Oregon, Bushnell University, and Lane Community College. The city is noted for its natural environment, recreational opportunities (especially bicycling, running/jogging, rafting, and kayaking), and focus on the arts, along with its history of civil unrest, protests, and green activism. Eugene's offi ...
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Muscle Contraction
Muscle contraction is the activation of tension-generating sites within muscle cells. In physiology, muscle contraction does not necessarily mean muscle shortening because muscle tension can be produced without changes in muscle length, such as when holding something heavy in the same position. The termination of muscle contraction is followed by muscle relaxation, which is a return of the muscle fibers to their low tension-generating state. For the contractions to happen, the muscle cells must rely on the interaction of two types of filaments which are the thin and thick filaments. Thin filaments are two strands of actin coiled around each, and thick filaments consist of mostly elongated proteins called myosin. Together, these two filaments form myofibrils which are important organelles in the skeletal muscle system. Muscle contraction can also be described based on two variables: length and tension. A muscle contraction is described as isometric if the muscle tension changes ...
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University Of California, San Francisco
The University of California, San Francisco (UCSF) is a public land-grant research university in San Francisco, California. It is part of the University of California system and is dedicated entirely to health science and life science. It conducts research and teaching in medical and biological sciences. UCSF was founded as Toland Medical College in 1864. in 1873, it became affiliated with the University of California as its Medical Department. In the same year, it incorporated the California College of Pharmacy and in 1881 it established a dentistry school. Its facilities were located in both Berkeley and San Francisco. In 1964, the school gained full administrative independence as a campus of the UC system, headed by its own chancellor, and in 1970 it gained its current name. Historically based at Parnassus Heights with satellite facilities throughout the city, UCSF developed a second major campus in the newly redeveloped Mission Bay district in the early 2000s. '' U.S. N ...
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Park Rapids, Minnesota
Park Rapids is a city in the Heartland Lakes region and is the county seat of Hubbard County, Minnesota, United States. It is near Itasca State Park, the source of the Mississippi River, as well as the beginning of the Heartland State Trail. The city was founded in 1890 near the Fish Hook River rapidsWarren Upham, (2008). ''Minnesota Geographic Names: Their Origin and Historic Significance''. Minnesota Historical Society, 1920. Harvard University. Digitized Aug 8, 2007. pp. 244 and is located along U.S. Highway 71 and Minnesota State Highway 34. The population was 4,142 at the 2020 census. History Park Rapids became a city in 1882, and was named by Frank C. Rice after the park groves and prairies beside the Fish Hook River rapids. These rapids have since been dammed. Infrastructure Transportation Park Rapids and the surrounding Hubbard County area have three major transportation services. South of the city center is Park Rapids Municipal Airport (officially Konshok Field), a ...
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Bad Medicine Lake
Bad Medicine Lake is a spring-fed lake located in Forest Township in Becker County, Minnesota. It got its name from the fact that early Native Americans in the area thought that a lake with neither inlet nor outlet was a place of bad omen ("bad medicine") and would not hunt or fish near the lake. The lake is approximately five miles long, a half mile wide, and reaches depths of up to . It is known for its clear, cold waters and rainbow trout fishing. It has experienced dramatic changes in its fish habitat and fish community in the last 35 years. Regarded as a bass/panfish lake in the 1950s and 1960s, the lake is now managed primarily for rainbow trout and walleye. The DNR turned Bad Medicine Lake into a trout lake in 1977, following an explosion of native crayfish that eliminated the vegetation used by bass and panfish. Roughly 16,000 rainbow trout are stocked annually, including Kamloops and Madison strains. There are three active resorts located on the lake. Bad Medicin ...
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Syntex
Laboratorios Syntex SA (later Syntex Laboratories, Inc.) was a pharmaceutical company formed in Mexico City in January 1944 by Russell Marker, Emeric Somlo, and Federico Lehmann to manufacture therapeutic steroids from the Mexican yams called ''cabeza de negro'' (''Dioscorea mexicana'') and ''Barbasco'' (''Dioscorea composita''). The demand for barbasco by Syntex initiated the Mexican barbasco trade. As the American Chemistry Society later explained: “In early 1944, the new Mexican company was chartered and named Syntex, S.A. (‘Synthesis and Mexico’). Russell Marker, shortly thereafter, left Syntex on account of his ruthless cofounder. Luis E. Miramontes, George Rosenkranz and Carl Djerassi's successful synthesis of norethindrone (also known as norethindrone) — which was later proven to be an effective pregnancy inhibitor — led to an infusion of capital into Syntex and the Mexican steroid pharmaceutical industry. George Rosenkranz and Carl Djerassi went on to synthesize ...
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