Derrick Dunlop
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Derrick Dunlop
Sir Derrick Melville Dunlop FRSE FRCP FRCPE FRCSE FDS LLD QHP (3 April 1902-9 June 1980) was a senior Scottish physician and pharmacologist at the forefront of British medical administration and policy-making in the late 20th century. He created the Dunlop Committee which investigates the side-effects of new drugs in the UK. Life Dunlop was born in Edinburgh on 3 April 1902 the son of Margaret Boog Scott and her husband, Dr George Henry (Harry) Melville Dunlop (185?-1916) of 20 Abercromby Place, an expert in child health and physician at the Edinburgh Sick Children’s Hospital. His father died of pneumonia at Etaples in France during the First World War. A Major in the Royal Army Medical Corps he was one of the oldest physicians to volunteer for active service. Dunlop attended Edinburgh Academy from 1909-1919. He attended Brasenose College, Oxford and then the University of Edinburgh, graduating with an MB ChB in 1926, followed by an MD gained in 1927. He worked briefly in L ...
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Derrick Dunlop
A derrick is a lifting device composed at minimum of one guyed mast, as in a gin pole, which may be articulated over a load by adjusting its guys. Most derricks have at least two components, either a guyed mast or self-supporting tower, and a boom hinged at its base to provide articulation, as in a ''stiffleg'' derrick. The most basic type of derrick is controlled by three or four lines connected to the top of the mast, which allow it both to move laterally and cant up and down. To lift a load, a separate line runs up and over the mast with a hook on its free end, as with a crane. Forms of derricks are commonly found aboard ships and at docking facilities. Some large derricks are mounted on dedicated vessels, and known as floating derricks and sheerlegs. The term derrick is also applied to the framework supporting a drilling apparatus in an oil rig. The derrick derives its name from a type of gallows named after Thomas Derrick, an Elizabethan era English executioner. Types ...
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Joyce Baird (diabetologist)
Joyce Baird (1929 - 2014) was a diabetes clinical and academic researcher, internationally cited for her work in both laboratory and clinical settings. Baird created the Metabolic disorder, Metabolic Unit at the Western General Hospital, Edinburgh and established a model of patient care that allowed those with endocrine disorders to monitor and treat themselves without supervision, and was organised in 'family friendly' hours. Baird was Vice President of the European Association for the Study of Diabetes. A new 'Baird Family Hospital' is opening in Aberdeen, Scotland in 2021, named for Joyce Baird, her parents and her brother's contribution to UK medicine. Early life and education Joyce Baird was born in Glasgow, Scotland on 24 June 1929 to a pioneering medical family. Baird moved to Aberdeen in 1937, where her father Sir Dugald Baird was Regius Professor of Midwifery at University of Aberdeen, Aberdeen University and led health care reforms for women in the UK and her mother La ...
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British Pharmacological Society
The British Pharmacological Society is the primary UK learned society for pharmacologists concerned with research into drugs and the way they work. Members work in academia, industry, regulatory agencies and the health services, and many are medically qualified. The Society covers the whole spectrum of pharmacology, including laboratory, clinical, and toxicological aspects. Clinical pharmacology is the medical speciality dedicated to promoting safe and effective use of medicines for patient benefit. Clinical pharmacologists work as consultants in the National Health Service and many hold prominent positions in UK universities. History The Society was founded in 1931, in Oxford, by a group of about 20 pharmacologists. They were brought together on the initiative of Professor James Andrew Gunn, by a letter signed by Gunn, H.H. Dale, and W.E. Dixon and sent to the heads of departments for teaching pharmacology and of institutions for pharmacological research in Great Britain, with p ...
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Medicines Commission
The Commission on Human Medicines (CHM) is a committee of the UK's Medicines and Healthcare products Regulatory Agency. It was formed in October 2005, and assumed the responsibilities of the Medicines Commission and the Committee on Safety of Medicines. Membership in this various and extensive body is listed oa governmental website The CHM's responsibilities include advising the UK government ministers on matters relating to regulation of human medicinal products, giving advice in relation to the safety, quality and efficacy of human medicinal products, and promoting the collection and investigation of information relating to adverse reactions for human medicines. Background to the establishment The Medicines and Healthcare products Regulatory Agency undertook a public consultation on proposals to amend the advisory body structure laid down in the Medicines Act 1968 in February 2005. Ministers agreed to a new structure with the establishment of the Commission that amalgamated the ...
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Committee On The Safety Of Medicines
The Committee on Safety of Medicines (CSM) was an independent advisory committee that advised the UK Licensing Authority on the quality, efficacy, and safety of medicines. Following the thalidomide tragedy of 1957 to 1961, in 1963 the government asked Sir Derrick Dunlop to set up a committee to investigate the control and introduction of new medicines in the United Kingdom. In June 1963 the Committee on Safety of Drugs (CSD) was established. As a result of the subsequent report to the Department of Health, which reinforced the need for specially trained doctors (clinical pharmacologists) in pharmaceutical companies and academic departments of medicine, Dunlop became the first chairman of the Committee. Under the Medicines Act 1968, the CSD was replaced in 1970 by the Medicines Commission, which established the Committee on Safety of Medicines (CSM) as a Government advisory committee under Section 4 of the Act. It was replaced on 30 October 2005 by the Commission on Human Medicin ...
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Thalidomide
Thalidomide, sold under the brand names Contergan and Thalomid among others, is a medication used to treat a number of cancers (including multiple myeloma), graft-versus-host disease, and a number of skin conditions including complications of leprosy. While it has been used in a number of HIV-associated conditions, such use is associated with increased levels of the virus. It is taken by mouth. Common side effects include sleepiness, rash, and dizziness. Severe side effects include tumor lysis syndrome, blood clots, and peripheral neuropathy. Use in pregnancy may harm the fetus, including resulting in malformation of the limbs. In males who are taking the medication, contraception is essential if a partner could become pregnant. It is an immunomodulatory medication and works by a number of mechanisms, including stimulating T cells and decreasing TNF-α production. Thalidomide was first marketed in 1957 in West Germany, where it was available over the counter. When first r ...
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Threipmuir Reservoir
Threipmuir Reservoir is a reservoir in the City of Edinburgh Council area, Scotland, UK. It is situated to the south of Edinburgh at the base of the Pentland Hills, two miles south of Balerno. Threipmuir reservoir is located behind an earth dam, constructed to a design by Scottish civil engineer James Jardine. The reservoir was formed between 1843 and 1848 as a compensation reservoir for the Water of Leith by the Edinburgh Water Company. The reservoir spillway discharges at the eastern end, from where the discharge flows into Harlaw Reservoir. Bavelaw Castle lies on its south side. See also *List of reservoirs and dams in the United Kingdom * Harlaw Reservoir *Harperrig Reservoir Harperrig Reservoir is a reservoir in West Lothian, Scotland, to the north of the Pentland Hills, south of Mid Calder. The Water of Leith flows through it, and nearby are Harlaw Reservoir and Threipmuir Reservoir. It has been proposed that th ... External links *  Scottish Government ...
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Balerno
Balerno (; gd, Baile Àirneach, IPA: paleˈɛːɾʲnəx Scots: Balerno or Balernie) is a village on the outskirts of Edinburgh, Scotland situated south-west of the city centre, next to Currie and then Juniper Green. Traditionally in the county of Midlothian it now administratively falls within the jurisdiction of the City of Edinburgh Council. The village lies at the confluence of the Water of Leith and the Bavelaw Burn. In the 18th and 19th century, the area was home to several mills using waterpower. In the 20th century, the mills closed and the village now forms a residential suburb of Edinburgh. History Balerno's name derives from the Scottish Gaelic ''Baile Àirneach'', meaning "townland/town of the hawthorns". The earliest written records of Balhernoch or Balernach are found in the late 13th century. The 18th century brought substantial development to the area, with several new flax, snuff and paper mills springing up around the Water of Leith and its tributary, the ...
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Bavelaw Castle
Bavelaw Castle is a historic house in the City of Edinburgh Council area, Scotland. It is north of Hare Hill in the Pentland Hills, four miles west of Penicuik, and two miles south of Balerno, above Threipmuir Reservoir. It was designated as a Category A listed building in 1971. History An early structure on the site was owned by the Braids, then by the Fairlies, but passed to the Forresters of Niddry by marriage. From them, it went to the Mowbrays of Barnbougle in the 16th century. Before Easter and Wester Bavelaw were granted by King James VI to Laurence Scott of Harperrig in 1628, a 16th-century L-plan tower house had been built by Walter Dundas. Both Mary, Queen of Scots, and James VI both stayed at Bavelaw, reputedly using it as a hunting lodge. Scott enlarged the tower house after his acquisition, possibly adding a small wing at the south-east angle. Bavelaw fell into a ruinous state, but was restored and extended in 1900 by Sir Robert Lorimer, linking the outbuildin ...
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Queen Elizabeth II
Elizabeth II (Elizabeth Alexandra Mary; 21 April 1926 – 8 September 2022) was Queen of the United Kingdom and other Commonwealth realms from 6 February 1952 until Death and state funeral of Elizabeth II, her death in 2022. She was queen regnant of List of sovereign states headed by Elizabeth II, 32 sovereign states during her lifetime, and was head of state of 15 realms at the time of her death. Her reign of 70 years and 214 days was the List of monarchs in Britain by length of reign, longest of any British monarch and the List of longest-reigning monarchs, longest verified reign of any female monarch in history. Elizabeth was born in Mayfair, London, as the first child of the Duke and Duchess of York (later King George VI and Queen Elizabeth The Queen Mother). Her father acceded to the throne in 1936 upon Abdication of Edward VIII, the abdication of his brother Edward VIII, making the ten-year-old Princess Elizabeth the heir presumptive. She was educated privat ...
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Aesculapian Club
The Aesculapian Club of Edinburgh is one of the oldest medical dining clubs in the world. It was founded in April 1773 by Dr. Andrew Duncan. Membership of the Club is limited to 11 Fellows of the Royal College of Physicians of Edinburgh and 11 Fellows of the Royal College of Surgeons of Edinburgh. 'Extraordinary Membership' is given to members aged over 70 years. The Club was established during the Scottish Enlightenment to encourage convivial relations between Fellows of the two Colleges and to stimulate intellectual discussion. The Club dinners are held in the New Library of the Royal College of Physicians of Edinburgh on the 2nd Friday of March and October each year. The principal guest at each dinner is invited to give a short talk on a non-medical subject and this is followed by a round-table discussion. Founding members There were 10 founding members of the Club who attended the first dinner on 2nd April 1773. The minutes of that meeting record that 'The Aesculapian ...
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Sydney Alfred Smith
Sir Sydney Alfred Smith CBE OPR FRSE LLD (4 August 1883 in Roxburgh, New Zealand – 8 May 1969 in Edinburgh, Scotland), was a renowned forensic scientist and pathologist. From 1928 to 1953, Smith was Regius Professor of Forensic Medicine at the University of Edinburgh, a well-known forensic department of that time. Smith's popular 1959 autobiography, ''Mostly Murder'', has run through many British and American editions, the latest in 1988. Life Smith was born at Roxburgh, Otago, in New Zealand the son of Mary Elizabeth Wilkinson and James Jackson Smith. He was educated at Roxburgh public school, and Victoria College, Wellington. He later won a Vans Dunlop scholarship to study botany and zoology at the University of Edinburgh. He transferred to medicine and graduated with an MB ChB in 1912, with first-class honours, and then undertook a research scholarship, receiving a Diploma in Public Health (DPH) in 1913. Following a short period in general practice, Smith became an ass ...
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