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Densovirinae
''Densovirinae'' is a subfamily of single-stranded DNA viruses in the family ''Parvoviridae''. The subfamily has 11 recognized genera and 21 species. Densoviruses are known to infect members of insect orders ''Blattodea'', ''Diptera'', ''Hemiptera'', ''Hymenoptera'', ''Lepidoptera'', and ''Orthoptera'', while some viruses infect and multiply in crustaceans such as shrimp or crayfish, or sea stars from phylum Echinodermata. Virology Densoviruses are small (18–26 nanometers in diameter) and non enveloped. Virions are icosahedral in shape with triangulation number (T) = 1. There are 60 copies of the coat protein in the virion. Each copy has a shape described as a "quadrilateral 'kite-shaped' wedge", and the appearance of the surface is rough with many small projections. Virions do not appear to contain lipids. Genomes are non-segmented, about 4–6 kilobases in length and usually contain two or three open reading frames. The 5' open reading frame encodes two nonstructural protein ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parvoviridae
Parvoviruses are a family of animal viruses that constitute the family ''Parvoviridae''. They have linear, single-stranded DNA (ssDNA) genomes that typically contain two genes encoding for a replication initiator protein, called NS1, and the protein the viral capsid is made of. The coding portion of the genome is flanked by telomeres at each end that form into hairpin loops that are important during replication. Parvovirus virions are small compared to most viruses, at 23–28 nanometers in diameter, and contain the genome enclosed in an icosahedral capsid that has a rugged surface. Parvoviruses enter a host cell by endocytosis, travelling to the nucleus where they wait until the cell enters its replication stage. At that point, the genome is uncoated and the coding portion is replicated. Viral messenger RNA (mRNA) is then transcribed and translated, resulting in NS1 initiating replication. During replication, the hairpins repeatedly unfold, are replicated, and refold to chang ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Iteradensovirus
''Iteradensovirus'' is a genus of viruses in the subfamily ''Densovirinae'' of the family ''Parvoviridae''. Insects serve as natural hosts. There are five species in this genus. Taxonomy The following five species are assigned to the genus: *''Lepidopteran iteradensovirus 1'' *''Lepidopteran iteradensovirus 2'' *''Lepidopteran iteradensovirus 3 Lepidoptera ( ) is an order of insects that includes butterflies and moths (both are called lepidopterans). About 180,000 species of the Lepidoptera are described, in 126 families and 46 superfamilies, 10 percent of the total described specie ...'' *'' Lepidopteran iteradensovirus 4'' *'' Lepidopteran iteradensovirus 5'' Structure Viruses in ''Iteradensovirus'' are non-enveloped, with icosahedral and Round geometries, and T=1 symmetry. The diameter is around 21-22 nm. Genomes are linear, around 5kb in length. Life cycle Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, whi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Taxonomy
Taxonomy is the practice and science of categorization or classification. A taxonomy (or taxonomical classification) is a scheme of classification, especially a hierarchical classification, in which things are organized into groups or types. Among other things, a taxonomy can be used to organize and index knowledge (stored as documents, articles, videos, etc.), such as in the form of a library classification system, or a search engine taxonomy, so that users can more easily find the information they are searching for. Many taxonomies are hierarchies (and thus, have an intrinsic tree structure), but not all are. Originally, taxonomy referred only to the categorisation of organisms or a particular categorisation of organisms. In a wider, more general sense, it may refer to a categorisation of things or concepts, as well as to the principles underlying such a categorisation. Taxonomy organizes taxonomic units known as "taxa" (singular "taxon")." Taxonomy is different from me ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Post-transcriptional Modification
Transcriptional modification or co-transcriptional modification is a set of biological processes common to most eukaryotic cells by which an RNA primary transcript is chemically altered following transcription from a gene to produce a mature, functional RNA molecule that can then leave the nucleus and perform any of a variety of different functions in the cell. There are many types of post-transcriptional modifications achieved through a diverse class of molecular mechanisms. One example is the conversion of precursor messenger RNA transcripts into mature messenger RNA that is subsequently capable of being translated into protein. This process includes three major steps that significantly modify the chemical structure of the RNA molecule: the addition of a 5' cap, the addition of a 3' polyadenylated tail, and RNA splicing. Such processing is vital for the correct translation of eukaryotic genomes because the initial precursor mRNA produced by transcription often contains both exo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcription (genetics)
Transcription is the process of copying a segment of DNA into RNA. The segments of DNA transcribed into RNA molecules that can encode proteins are said to produce messenger RNA (mRNA). Other segments of DNA are copied into RNA molecules called non-coding RNAs (ncRNAs). mRNA comprises only 1–3% of total RNA samples. Less than 2% of the human genome can be transcribed into mRNA ( Human genome#Coding vs. noncoding DNA), while at least 80% of mammalian genomic DNA can be actively transcribed (in one or more types of cells), with the majority of this 80% considered to be ncRNA. Both DNA and RNA are nucleic acids, which use base pairs of nucleotides as a complementary language. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, antiparallel RNA strand called a primary transcript. Transcription proceeds in the following general steps: # RNA polymerase, together with one or more general transcription factors, binds to promoter DNA ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Viral Replication
Viral replication is the formation of biological viruses during the infection process in the target host cells. Viruses must first get into the cell before viral replication can occur. Through the generation of abundant copies of its genome and packaging these copies, the virus continues infecting new hosts. Replication between viruses is greatly varied and depends on the type of genes involved in them. Most DNA viruses assemble in the nucleus while most RNA viruses develop solely in cytoplasm. Viral production / replication Viruses multiply only in living cells. The host cell must provide the energy and synthetic machinery and the low- molecular-weight precursors for the synthesis of viral proteins and nucleic acids. The virus replication occurs in seven stages, namely; # Attachment # Entry, # Uncoating, # Transcription / mRNA production, # Synthesis of virus components, # Virion assembly and # Release (Liberation Stage). Attachment It is the first step of viral replication ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
