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Dennis A. Dougherty
Dennis A. Dougherty (born December 4, 1952, in Harrisburg, Pennsylvania) is the George Grant Hoag Professor of Chemistry at California Institute of Technology. His research applies physical organic chemistry to systems of biological importance. Dougherty utilizes a variety of approaches to further our understanding of the human brain, including the ''in vivo'' nonsense suppression methodology for incorporating unnatural amino acids into a variety of ion channels for structure-function studies. Education Dougherty received his B.S. and M.S. in 1974 from Bucknell University. Subsequently, he earned his Ph.D. in 1978 under the supervision of Kurt Mislow at Princeton University and was a post-doctoral scholar in Jerome Berson's lab at Yale University in 1979. Career In 1979 Dougherty became a member of the Caltech faculty, earning tenure in 1985. He is the scientific co-founder of Neurion Pharmaceuticals, Inc. In 2005 he published a textbook entitled ''Modern Physical Organic Ch ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harrisburg, Pennsylvania
Harrisburg is the capital city of the Commonwealth of Pennsylvania, United States, and the county seat of Dauphin County. With a population of 50,135 as of the 2021 census, Harrisburg is the 9th largest city and 15th largest municipality in Pennsylvania. Harrisburg is situated on the east bank of the Susquehanna River. It is the larger principal city of the Harrisburg–Carlisle metropolitan statistical area, also known as the Susquehanna Valley, which had a population of 591,712 as of 2020, making it the fourth most populous metropolitan area in Pennsylvania after the Philadelphia, Pittsburgh, and Lehigh Valley metropolitan areas. Harrisburg played a role in American history during the Westward Migration, the American Civil War, and the Industrial Revolution. During part of the 19th century, the building of the Pennsylvania Canal and later the Pennsylvania Railroad allowed Harrisburg to develop into one of the most industrialized cities in the Northeastern United States. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ion Channel
Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore. Their functions include establishing a resting membrane potential, shaping action potentials and other electrical signals by gating the flow of ions across the cell membrane, controlling the flow of ions across secretory and epithelial cells, and regulating cell volume. Ion channels are present in the membranes of all cells. Ion channels are one of the two classes of ionophoric proteins, the other being ion transporters. The study of ion channels often involves biophysics, electrophysiology, and pharmacology, while using techniques including voltage clamp, patch clamp, immunohistochemistry, X-ray crystallography, fluoroscopy, and RT-PCR. Their classification as molecules is referred to as channelomics. Basic features There are two distinctive features of ion channels that differentiate them from other types of ion transporter proteins: #The rate of ion transport through the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Harrisburg, Pennsylvania
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1952 Births
Year 195 ( CXCV) was a common year starting on Wednesday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Scrapula and Clemens (or, less frequently, year 948 ''Ab urbe condita''). The denomination 195 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Emperor Septimius Severus has the Roman Senate deify the previous emperor Commodus, in an attempt to gain favor with the family of Marcus Aurelius. * King Vologases V and other eastern princes support the claims of Pescennius Niger. The Roman province of Mesopotamia rises in revolt with Parthian support. Severus marches to Mesopotamia to battle the Parthians. * The Roman province of Syria is divided and the role of Antioch is diminished. The Romans annexed the Syrian cities of Edessa and Nisibis. Severus re-establish his h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
21st-century American Chemists
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius ( AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman em ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lawndale Elementary School District
Lawndale Elementary School District (LESD) is a school district headquartered in Lawndale, California, United States. The district educates residents in: Lawndale, and portions of Hawthorne, as well as unincorporated areas in Los Angeles County (including Alondra Park). {{Education in Los Angeles County, California School districts in Los Angeles County, California Lawndale, California Hawthorne, California ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Society For Neuroscience
The Society for Neuroscience (SfN) is a professional society, headquartered in Washington, DC, for basic scientists and physicians around the world whose research is focused on the study of the brain and nervous system. It is especially well known for its annual meeting, consistently one of the largest scientific conferences in the world. History SfN was founded in 1969 by Ralph W. Gerard and, at nearly 37,000 members, has grown to be the largest neuroscience society in the world. The stated mission of the society is to: #Advance the understanding of the brain and the nervous system. #Provide professional development activities, information, and educational resources. #Promote public information and general education about science and neuroscience. #Inform legislators and other policy makers about the implications of research for public policy, societal benefit, and continued scientific progress. Annual meeting The Society holds an annual meeting that is attended by scien ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biophysical Society
The Biophysical Society is an international scientific society whose purpose is to lead the development and dissemination of knowledge in biophysics. Founded in 1958, the Society currently consists of over 7,500 members in academia, government, and industry. Although the Society is based in the United States, it is an international organization. Overseas members currently comprise over one third of the total. Origins The Biophysical Society was founded in response to the growth of the field of biophysics after World War Two, as well as concerns that the American Physiological Society had become too large to serve the community of biophysicists. Discussions between prominent biophysicists in 1955 and 1956 led to the planning of the society's first meeting in Columbus, Ohio in 1957, with about 500 attendees. Among the scientists involved in the early effort were Ernest C. Pollard, Samuel Talbot, Otto Schmitt, Kenneth Stewart Cole, W. A. Selle, Max Lauffer, Ralph Stacy, Herma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c) organization, 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio. The ACS is a leading source of scientific information through its peer-reviewed scientific journals, national conferences, and the Chemical Abstracts Service. Its publications division produces over 60 Scientific journal, scholarly journals including the prestigious ''Journal of the American Chemical Society'', as well as the weekly tra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phi Beta Kappa
The Phi Beta Kappa Society () is the oldest academic honor society in the United States, and the most prestigious, due in part to its long history and academic selectivity. Phi Beta Kappa aims to promote and advocate excellence in the liberal arts and sciences, and to induct the most outstanding students of arts and sciences at only select American colleges and universities. It was founded at the College of William and Mary on December 5, 1776, as the first collegiate Greek-letter fraternity and was among the earliest collegiate fraternal societies. Since its inception, 17 U.S. Presidents, 40 U.S. Supreme Court Justices, and 136 Nobel Laureates have been inducted members. Phi Beta Kappa () stands for ('), which means "Wisdom it. love of knowledgeis the guide it. helmsmanof life". Membership Phi Beta Kappa has chapters in only about 10% of American higher learning institutions, and only about 10% of these schools' Arts and Sciences graduates are invited to join the society. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scien ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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