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Denis Buican
Denis Buican (born ''Dumitru Buican-Peligrad''; 21 December 1934 in Bucharest) is a Romanian-French scientist, bilingual writer, biologist, philosopher and a historian of science. He has studied genetics. Background His father Dumitru Peligrad a boyar and philanthropist was placed under house arrest after the invasion of Romania by the Red Army (starting 23 August 1944), but he refused to submit to regular police checks. Although belonging to a class deemed "unhealthy" by the then communist regime, the young researcher was a brilliant undergraduate at the University of Bucharest. Pioneer of Romanian radio-genetics (his first studies focused on the influence of electricity on the life of plants), agronomist (1956), Doctor (Ph.D) in Genetics (1961), then a professor at the University of Bucharest, he fought theories of Lysenkoism, imposed by the ex-USSR in the former so-called "popular democratic" countries of Central and Eastern Europe. After 1948 his laboratories were destroyed ...
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Denis Buican
Denis Buican (born ''Dumitru Buican-Peligrad''; 21 December 1934 in Bucharest) is a Romanian-French scientist, bilingual writer, biologist, philosopher and a historian of science. He has studied genetics. Background His father Dumitru Peligrad a boyar and philanthropist was placed under house arrest after the invasion of Romania by the Red Army (starting 23 August 1944), but he refused to submit to regular police checks. Although belonging to a class deemed "unhealthy" by the then communist regime, the young researcher was a brilliant undergraduate at the University of Bucharest. Pioneer of Romanian radio-genetics (his first studies focused on the influence of electricity on the life of plants), agronomist (1956), Doctor (Ph.D) in Genetics (1961), then a professor at the University of Bucharest, he fought theories of Lysenkoism, imposed by the ex-USSR in the former so-called "popular democratic" countries of Central and Eastern Europe. After 1948 his laboratories were destroyed ...
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Modern Synthesis (20th Century)
The modern synthesis was the early 20th-century synthesis of Charles Darwin's theory of evolution and Gregor Mendel's ideas on heredity into a joint mathematical framework. Julian Huxley coined the term in his 1942 book, ''Evolution: The Modern Synthesis''. The synthesis combined the ideas of natural selection, Mendelian inheritance, Mendelian genetics, and population genetics. It also related the broad-scale macroevolution seen by paleontology, palaeontologists to the small-scale microevolution of local population, populations. The synthesis was defined differently by its founders, with Ernst Mayr in 1959, G. Ledyard Stebbins in 1966, and Theodosius Dobzhansky in 1974 offering differing basic postulates, though they all include natural selection, working on heritable variation supplied by mutation. Other major figures in the synthesis included E. B. Ford, Bernhard Rensch, Ivan Schmalhausen, and George Gaylord Simpson. An early event in the modern synthesis was R. A. Fisher's ...
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Science Of Heredity
Heredity, also called inheritance or biological inheritance, is the passing on of traits from parents to their offspring; either through asexual reproduction or sexual reproduction, the offspring cells or organisms acquire the genetic information of their parents. Through heredity, variations between individuals can accumulate and cause species to evolve by natural selection. The study of heredity in biology is genetics. Overview In humans, eye color is an example of an inherited characteristic: an individual might inherit the "brown-eye trait" from one of the parents. Inherited traits are controlled by genes and the complete set of genes within an organism's genome is called its genotype. The complete set of observable traits of the structure and behavior of an organism is called its phenotype. These traits arise from the interaction of its genotype with the environment. As a result, many aspects of an organism's phenotype are not inherited. For example, suntanned sk ...
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The Structure Of Scientific Revolutions
''The Structure of Scientific Revolutions'' (1962; second edition 1970; third edition 1996; fourth edition 2012) is a book about the history of science by philosopher Thomas S. Kuhn. Its publication was a landmark event in the history, philosophy, and sociology of science. Kuhn challenged the then prevailing view of progress in science in which scientific progress was viewed as "development-by-accumulation" of accepted facts and theories. Kuhn argued for an episodic model in which periods of conceptual continuity where there is cumulative progress, which Kuhn referred to as periods of "normal science", were interrupted by periods of revolutionary science. The discovery of "anomalies" during revolutions in science leads to new paradigms. New paradigms then ask new questions of old data, move beyond the mere "puzzle-solving" of the previous paradigm, change the rules of the game and the "map" directing new research. For example, Kuhn's analysis of the Copernican Revolution emphasi ...
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Thomas Kuhn
Thomas Samuel Kuhn (; July 18, 1922 – June 17, 1996) was an American philosopher of science whose 1962 book ''The Structure of Scientific Revolutions'' was influential in both academic and popular circles, introducing the term '' paradigm shift'', which has since become an English-language idiom. Kuhn made several claims concerning the progress of scientific knowledge: that scientific fields undergo periodic "paradigm shifts" rather than solely progressing in a linear and continuous way, and that these paradigm shifts open up new approaches to understanding what scientists would never have considered valid before; and that the notion of scientific truth, at any given moment, cannot be established solely by objective criteria but is defined by a consensus of a scientific community. Competing paradigms are frequently incommensurable; that is, they are competing and irreconcilable accounts of reality. Thus, our comprehension of science can never rely wholly upon "objectivity ...
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Immanuel Kant
Immanuel Kant (, , ; 22 April 1724 – 12 February 1804) was a German philosopher and one of the central Enlightenment thinkers. Born in Königsberg, Kant's comprehensive and systematic works in epistemology, metaphysics, ethics, and aesthetics have made him one of the most influential figures in modern Western philosophy. In his doctrine of transcendental idealism, Kant argued that space and time are mere "forms of intuition" which structure all experience, and therefore that, while " things-in-themselves" exist and contribute to experience, they are nonetheless distinct from the objects of experience. From this it follows that the objects of experience are mere "appearances", and that the nature of things as they are in themselves is unknowable to us. In an attempt to counter the skepticism he found in the writings of philosopher David Hume, he wrote the '' Critique of Pure Reason'' (1781/1787), one of his most well-known works. In it, he developed his theory of ...
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Kantian
Kantianism is the philosophy of Immanuel Kant, a German philosopher born in Königsberg, Prussia (now Kaliningrad, Russia). The term ''Kantianism'' or ''Kantian'' is sometimes also used to describe contemporary positions in philosophy of mind, epistemology, and ethics. Ethics Kantian ethics are deontological, revolving entirely around duty rather than emotions or end goals. All actions are performed in accordance with some underlying maxim or principle, which are vastly different from each other; it is according to this that the moral worth of any action is judged. Kant's ethics are founded on his view of rationality as the ultimate good and his belief that all people are fundamentally rational beings. This led to the most important part of Kant's ethics, the formulation of the categorical imperative, which is the criterion for whether a maxim is good or bad. Simply put, this criterion amounts to a thought experiment: to attempt to universalize the maxim (by imagining a worl ...
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Genetic Engineering
Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA is obtained by either isolating and copying the genetic material of interest using recombinant DNA methods or by artificially synthesising the DNA. A construct is usually created and used to insert this DNA into the host organism. The first recombinant DNA molecule was made by Paul Berg in 1972 by combining DNA from the monkey virus SV40 with the lambda virus. As well as inserting genes, the process can be used to remove, or "knock out", genes. The new DNA can be inserted randomly, or targeted to a specific part of the genome. An organism that is generated through genetic engineering is considered to be genetically modified (GM) an ...
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La Nouvelle Revue Française
LA most frequently refers to Los Angeles, the second largest city in the United States. La, LA, or L.A. may also refer to: Arts and entertainment Music * La (musical note), or A, the sixth note * "L.A.", a song by Elliott Smith on ''Figure 8'' (album) * ''L.A.'' (EP), by Teddy Thompson * ''L.A. (Light Album)'', a Beach Boys album * "L.A." (Neil Young song), 1973 * The La's, an English rock band * L.A. Reid, a prominent music producer * Yung L.A., a rapper * Lady A, an American country music trio * "L.A." (Amy Macdonald song), 2007 * "La", a song by Australian-Israeli singer-songwriter Old Man River Other media * l(a, a poem by E. E. Cummings * La (Tarzan), fictional queen of the lost city of Opar (Tarzan) * ''Lá'', later known as Lá Nua, an Irish language newspaper * La7, an Italian television channel * LucasArts, an American video game developer and publisher * Liber Annuus, academic journal Business, organizations, and government agencies * L.A. Screenings, a tel ...
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Orthodromic
An orthodromic action potential, impulse runs along an axon in its Anterograde Tracing, anterograde direction, away from the Soma (biology), soma. In the heart, orthodromic may also refer to an impulse going in the correct direction from the dendrites to axon terminal (from the atrium (heart), atria to the ventricle (heart), ventricles) in contrast to some impulses in Cardiac dysrhythmia#Re-entry, re-entry. See also *Antidromic *Action potential *Anterograde Tracing References

Neurophysiology {{Neuroscience-stub ...
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Nobel Prize
The Nobel Prizes ( ; sv, Nobelpriset ; no, Nobelprisen ) are five separate prizes that, according to Alfred Nobel's will of 1895, are awarded to "those who, during the preceding year, have conferred the greatest benefit to humankind." Alfred Nobel was a Swedish chemist, engineer, and industrialist most famously known for the invention of dynamite. He died in 1896. In his will, he bequeathed all of his "remaining realisable assets" to be used to establish five prizes which became known as "Nobel Prizes." Nobel Prizes were first awarded in 1901. Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace (Nobel characterized the Peace Prize as "to the person who has done the most or best to advance fellowship among nations, the abolition or reduction of standing armies, and the establishment and promotion of peace congresses"). In 1968, Sveriges Riksbank (Sweden's central bank) funded the establishment of the Prize in Economi ...
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Jacques Monod
Jacques Lucien Monod (February 9, 1910 – May 31, 1976) was a French biochemist who won the Nobel Prize in Physiology or Medicine in 1965, sharing it with François Jacob and André Lwoff "for their discoveries concerning genetic control of enzyme and virus synthesis".'' Chance and Necessity: An Essay on the Natural Philosophy of Modern Biology'' by Jacques Monod, New York, Alfred A. Knopf, 1971, Monod and Jacob became famous for their work on the '' E. coli'' ''lac'' operon, which encodes proteins necessary for the transport and breakdown of the sugar lactose (lac). From their own work and the work of others, they came up with a model for how the levels of some proteins in a cell are controlled. In their model, the manufacture of proteins, such as the ones encoded within the ''lac'' (lactose) operon, is prevented when a repressor, encoded by a regulatory gene, binds to its operator, a specific site in the DNA sequence that is close to the genes encoding the proteins. (It is ...
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