Delphinium Ajacis
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Delphinium Ajacis
''Consolida ajacis'' (doubtful knight's spur or rocket larkspur) is an annual flowering plant of the family Ranunculaceae native to Eurasia. It is widespread in other areas, including much of North America, where it is an introduced species. It is frequently grown in gardens as an ornamental for its spikes of blue, pink or white flowers. It may reach a meter in height. Since the aerial parts and seeds of ''C. ajacis'' have been found to contain diterpenoid alkaloids (see below), including the highly toxic methyllycaconitine, the plants should be considered as poisonous. Sowing In the UK, ''Consolida ajacis'' can be sowed under cover between February and April, or directly outdoors between April and May and/or late August and September. Flowering In Europe, it flowers between June and October. Chemical constituents The first alkaloid to be isolated from ''C. ajacis'' seeds was ajaconine, reported by Keller and Volker in 1914. Since that time, over thirty other structurally re ...
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Carl Linnaeus
Carl Linnaeus (; 23 May 1707 – 10 January 1778), also known after his ennoblement in 1761 as Carl von Linné Blunt (2004), p. 171. (), was a Swedish botanist, zoologist, taxonomist, and physician who formalised binomial nomenclature, the modern system of naming organisms. He is known as the "father of modern taxonomy". Many of his writings were in Latin; his name is rendered in Latin as and, after his 1761 ennoblement, as . Linnaeus was born in Råshult, the countryside of Småland, in southern Sweden. He received most of his higher education at Uppsala University and began giving lectures in botany there in 1730. He lived abroad between 1735 and 1738, where he studied and also published the first edition of his ' in the Netherlands. He then returned to Sweden where he became professor of medicine and botany at Uppsala. In the 1740s, he was sent on several journeys through Sweden to find and classify plants and animals. In the 1750s and 1760s, he continued to collect an ...
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Delcosine
Delsoline and delcosine are two closely related naturally occurring diterpene alkaloids first isolated from ''Delphinium consolida''. They occur widely in the Ranunculaceae plant family. The polycyclic ring system containing nineteen carbon atoms and one nitrogen atom in these compounds is the same as in aconitine and this is reflected in their preferred IUPAC name. History Delsoline and delcosine were named in 1924 by Markwood, who isolated these alkaloids from Delphinium consolida, but their structures were in doubt until established in 1963 and later confirmed by the X-ray crystallography of delsoline. There are many other known diterpene alkaloids, some of which differ from these in only minor ways. Thus while delsoline (R=CH3) is a methylated derivative of delcosine (R=H), it is also an isomeric methyl derivative of gigactonine. Synthesis Although individual members of this class of alkaloids have been extensively studied, their chemical complexity has limited the number ...
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