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Dawn Simulation
Dawn simulation is a technique that involves timing lights, often called wake up lights, sunrise alarm clock or natural light alarm clocks, in the bedroom to come on gradually, over a period of 30 minutes to 2 hours, before awakening to simulate dawn. History The concept of dawn simulation was first patented in 1890 as "mechanical sunrise". Modern electronic units were patented in 1973. Variations and improvements seem to get patented every few years. Clinical trials were conducted by David Avery, MD, in the 1980s at Columbia University following a long line of basic laboratory research that showed animals' circadian rhythms to be exquisitely sensitive to the dim, gradually rising dawn signal at the end of the night. Clinical use There are two types of dawn that have been used effectively in a clinical setting: a naturalistic dawn mimicking a springtime sunrise (but used in mid-winter when it is still dark outside), and a sigmoidal-shaped dawn (30 minutes to 2 hours). When used su ...
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Davita Vitaclock 200
DaVita Inc. provides kidney dialysis services through a network of 2,816 outpatient dialysis centers in the United States, serving 204,200 patients, and 321 outpatient dialysis centers in 10 other countries serving 3,200 patients. The company primarily treats end-stage renal disease (ESRD), which requires patients to undergo dialysis 3 times per week for the rest of their lives unless they receive a donor kidney. The company has a 37% market share in the U.S. dialysis market. It is organized in Delaware and based in Denver. In 2020, 68% of the company's revenues came from Medicare and other government-based health insurance programs. In 2020, 90% of the company's patients were covered by government-based health insurance programs. Commercial payers, which accounted for 32% of revenues in 2020, generate nearly all of the company's profit as they reimburse at a much higher rate than government-based health insurance programs. The company is ranked 271st on the Fortune 500. The na ...
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Dawn
Dawn is the time that marks the beginning of twilight before sunrise. It is recognized by the appearance of indirect sunlight being scattered in Earth's atmosphere, when the centre of the Sun's disc has reached 18° below the observer's horizon. This morning twilight period will last until sunrise (when the Sun's upper limb breaks the horizon), when direct sunlight outshines the diffused light. Etymology "Dawn" derives from the Old English verb ''dagian'', "to become day". Types of dawn Dawn begins with the first sight of lightness in the morning, and continues until the Sun breaks the horizon. This morning twilight before sunrise is divided into three categories depending on the amount of sunlight that is present in the sky, which is determined by the angular distance of the centre of the Sun (degrees below the horizon) in the morning. These categories are ''astronomical'', ''nautical'', and ''civil dawn''. Astronomical dawn Astronomical dawn begins when the Sun is 18 ...
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Columbia University
Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhattan, Columbia is the oldest institution of higher education in New York and the fifth-oldest institution of higher learning in the United States. It is one of nine colonial colleges founded prior to the Declaration of Independence. It is a member of the Ivy League. Columbia is ranked among the top universities in the world. Columbia was established by royal charter under George II of Great Britain. It was renamed Columbia College in 1784 following the American Revolution, and in 1787 was placed under a private board of trustees headed by former students Alexander Hamilton and John Jay. In 1896, the campus was moved to its current location in Morningside Heights and renamed Columbia University. Columbia scientists and scholars have ...
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Circadian Rhythms
A circadian rhythm (), or circadian cycle, is a natural, internal process that regulates the sleep–wake cycle and repeats roughly every 24 hours. It can refer to any process that originates within an organism (i.e., endogenous) and responds to the environment ( entrained by the environment). These 24-hour rhythms are driven by a circadian clock, and they have been widely observed in animals, plants, fungi and cyanobacteria. The term ''circadian'' comes from the Latin ''circa'', meaning "approximately", and ''dies'', meaning "day". Processes with 24-hour cycles are more generally called diurnal rhythms; diurnal rhythms should not be called circadian rhythms unless they can be confirmed as endogenous, and not environmental. Although circadian rhythms are endogenous, they are adjusted to the local environment by external cues called zeitgebers (German for "time givers"), which include light, temperature and redox cycles. In clinical settings, an abnormal circadian rhythm in humans ...
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Sunrise
Sunrise (or sunup) is the moment when the upper rim of the Sun appears on the horizon in the morning. The term can also refer to the entire process of the solar disk crossing the horizon and its accompanying atmospheric effects. Terminology Although the Sun appears to "rise" from the horizon, it is actually the ''Earth's'' motion that causes the Sun to appear. The illusion of a moving Sun results from Earth observers being in a rotating reference frame; this apparent motion is so convincing that many cultures had mythologies and religions built around the geocentric model, which prevailed until astronomer Nicolaus Copernicus formulated his heliocentric model in the 16th century. Architect Buckminster Fuller proposed the terms "sunsight" and "sunclipse" to better represent the heliocentric model, though the terms have not entered into common language. Astronomically, sunrise occurs for only an instant: the moment at which the upper limb of the Sun appears tangent to the horizon ...
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Sigmoid Function
A sigmoid function is a mathematical function having a characteristic "S"-shaped curve or sigmoid curve. A common example of a sigmoid function is the logistic function shown in the first figure and defined by the formula: :S(x) = \frac = \frac=1-S(-x). Other standard sigmoid functions are given in the Examples section. In some fields, most notably in the context of artificial neural networks, the term "sigmoid function" is used as an alias for the logistic function. Special cases of the sigmoid function include the Gompertz curve (used in modeling systems that saturate at large values of x) and the ogee curve (used in the spillway of some dams). Sigmoid functions have domain of all real numbers, with return (response) value commonly monotonically increasing but could be decreasing. Sigmoid functions most often show a return value (y axis) in the range 0 to 1. Another commonly used range is from −1 to 1. A wide variety of sigmoid functions including the logistic and hype ...
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Phase Response Curve
A phase response curve (PRC) illustrates the transient change (phase response) in the cycle period of an oscillation induced by a perturbation as a function of the phase at which it is received. PRCs are used in various fields; examples of biological oscillations are the heartbeat, circadian rhythms, and the regular, repetitive firing observed in some neurons in the absence of noise. In circadian rhythms In humans and animals, there is a regulatory system that governs the phase relationship of an organism's internal circadian clock to a regular periodicity in the external environment (usually governed by the solar day). In most organisms, a stable phase relationship is desired, though in some cases the desired phase will vary by season, especially among mammals with seasonal mating habits. In circadian rhythm research, a PRC illustrates the relationship between a chronobiotic's time of administration (relative to the internal circadian clock) and the magnitude of the treatment' ...
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Illuminance
In photometry, illuminance is the total luminous flux incident on a surface, per unit area. It is a measure of how much the incident light illuminates the surface, wavelength-weighted by the luminosity function to correlate with human brightness perception.International Electrotechnical Commission (IEC): ''International Electrotechnical Vocabulary.'ref. 845-21-060, illuminance/ref> Similarly, luminous emittance is the luminous flux per unit area emitted from a surface. Luminous emittance is also known as luminous exitance. In SI units illuminance is measured in lux (lx), or equivalently in lumens per square metre ( lm· m−2). Luminous exitance is measured in lm·m−2 only, not lux. International Electrotechnical Commission (IEC): ''International Electrotechnical Vocabulary.'ref. 845-21-081, luminous exitance/ref> In the CGS system, the unit of illuminance is the phot, which is equal to . The foot-candle is a non-metric unit of illuminance that is used in photography. Ill ...
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Bright Light Therapy
Light therapy, also called phototherapy or bright light therapy is intentional daily exposure to direct sunlight or similar-intensity artificial light in order to treat medical disorders, especially seasonal affective disorder (SAD) and circadian rhythm sleep-wake disorders. Treating skin conditions such as neurodermatitis, psoriasis, acne vulgaris, and eczema with ultraviolet light is called ultraviolet light therapy. Medical uses Nutrient deficiency Vitamin D deficiency Exposure to light at specific wavelengths of Ultraviolet B (abbreviated as UV-B or UVB) enables the body to produce vitamin D to treat vitamin D deficiency. Skin conditions Light therapy treatments for the skin usually involve exposure to ultraviolet light. The exposures can be to a small area of the skin or over the whole body surface, as in a tanning bed. The most common treatment is with narrowband UVB, which has a wavelength of approximately 311–313 nanometers. Full body phototherapy can be d ...
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Seasonal Affective Disorder
Seasonal affective disorder (SAD) is a mood disorder subset, in which people who have normal mental health throughout most of the year exhibit depressive symptoms at the same time each year. Common symptoms include sleeping too much, having little to no energy, and overeating. The condition in the summer can include heightened anxiety.Seasonal affective disorder (SAD): Symptoms
MayoClinic.com (September 22, 2011). Retrieved on March 24, 2013.
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Sunset
Sunset, also known as sundown, is the daily disappearance of the Sun below the horizon due to Earth's rotation. As viewed from everywhere on Earth (except the North and South poles), the equinox Sun sets due west at the moment of both the spring and autumn equinoxes. As viewed from the Northern Hemisphere, the Sun sets to the northwest (or not at all) in the spring and summer, and to the southwest in the autumn and winter; these seasons are reversed for the Southern Hemisphere. The time of sunset is defined in astronomy as the moment when the upper limb of the Sun disappears below the horizon. Near the horizon, atmospheric refraction causes sunlight rays to be distorted to such an extent that geometrically the solar disk is already about one diameter below the horizon when a sunset is observed. Sunset is distinct from twilight, which is divided into three stages. The first one is ''civil twilight'', which begins once the Sun has disappeared below the horizon, and continues until ...
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Delayed Sleep Phase Syndrome
Delayed sleep phase disorder (DSPD), more often known as delayed sleep phase syndrome and also as delayed sleep–wake phase disorder, is a delaying of a person's circadian rhythm (biological clock) compared to those of societal norms. The disorder affects the timing of biological rhythms including sleep, peak period of alertness, core body temperature, and hormonal cycles. The diagnosis of this disorder is currently a point of contention among specialists of sleep disorders. Many insomnia-related disorders can present significantly differently between patients, and circadian rhythm disorders and melatonin related disorders are not well understood by modern medical science. The orexin system was identified only in 1998, yet it appears intimately implicated in human sleep-wake systems. Evidence for the plasticity of human circadian rhythm cycles has been provided by multiple studies. In one example, several dozen volunteers spent many months underground in a French cave, w ...
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