David Pressman (scientist)
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David Pressman (scientist)
David Pressman was an American immunologist. He graduated from the California Institute of Technology in 1937 and received his PhD from the same institution in 1940. He remained at Caltech as a research fellow until 1947. During that time, he worked with Linus Pauling and Dan H. Campbell and the three published highly influential work on antibodies and antigens. Pressman then joined the faculty at the Sloan-Kettering Institute. He later moved to Roswell Park Comprehensive Cancer Center Roswell Park Comprehensive Cancer Center is a cancer research and treatment center located in Buffalo, New York. Founded by surgeon Roswell Park in 1898, the center was the first in the United States to specifically focus on cancer research. The .... Among the influential members of his research group were Herman Eisen, Arthur Silverstein, and Alfred Nisonoff. References American immunologists California Institute of Technology alumni Year of birth missing Year of death missing ...
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California Institute Of Technology
The California Institute of Technology (branded as Caltech or CIT)The university itself only spells its short form as "Caltech"; the institution considers other spellings such a"Cal Tech" and "CalTech" incorrect. The institute is also occasionally referred to as "CIT", most notably in its alma mater, but this is uncommon. is a private research university in Pasadena, California. Caltech is ranked among the best and most selective academic institutions in the world, and with an enrollment of approximately 2400 students (acceptance rate of only 5.7%), it is one of the world's most selective universities. The university is known for its strength in science and engineering, and is among a small group of institutes of technology in the United States which is primarily devoted to the instruction of pure and applied sciences. The institution was founded as a preparatory and vocational school by Amos G. Throop in 1891 and began attracting influential scientists such as George Ellery H ...
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Linus Pauling
Linus Carl Pauling (; February 28, 1901August 19, 1994) was an American chemist, biochemist, chemical engineer, peace activist, author, and educator. He published more than 1,200 papers and books, of which about 850 dealt with scientific topics. ''New Scientist'' called him one of the 20 greatest scientists of all time, and as of 2000, he was rated the 16th most important scientist in history. For his scientific work, Pauling was awarded the Nobel Prize in Chemistry in 1954. For his peace activism, he was awarded the Nobel Peace Prize in 1962. He is one of five people to have won more than one Nobel Prize (the others being Marie Curie, John Bardeen, Frederick Sanger and Karl Barry Sharpless). Of these, he is the only person to have been awarded two unshared Nobel Prizes, and one of two people to be awarded Nobel Prizes in different fields, the other being Marie Curie. Pauling was one of the founders of the fields of quantum chemistry and molecular biology. His contributions t ...
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Dan H
Dan or DAN may refer to: People * Dan (name), including a list of people with the name ** Dan (king), several kings of Denmark * Dan people, an ethnic group located in West Africa **Dan language, a Mande language spoken primarily in Côte d'Ivoire and Liberia * Dan (son of Jacob), one of the 12 sons of Jacob/Israel in the Bible **Tribe of Dan, one of the 12 tribes of Israel descended from Dan * Crown Prince Dan, prince of Yan in ancient China Places * Dan (ancient city), the biblical location also called Dan, and identified with Tel Dan * Dan, Israel, a kibbutz * Dan, subdistrict of Kap Choeng District, Thailand * Dan, West Virginia, an unincorporated community in the United States * Dan River (other) * Danzhou, formerly Dan County, China * Gush Dan, the metropolitan area of Tel Aviv in Israel Organizations *Dan-Air, a defunct airline in the United Kingdom *Dan Bus Company, a public transport company in Israel *Dan Hotels, a hotel chain in Israel *Dan the Tire Man, a ...
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Antibodies
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few vari ...
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Antigens
In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response. The term ''antigen'' originally referred to a substance that is an antibody generator. Antigens can be proteins, peptides (amino acid chains), polysaccharides (chains of monosaccharides/simple sugars), lipids, or nucleic acids. Antigens are recognized by antigen receptors, including antibodies and T-cell receptors. Diverse antigen receptors are made by cells of the immune system so that each cell has a specificity for a single antigen. Upon exposure to an antigen, only the lymphocytes that recognize that antigen are activated and expanded, a process known as clonal selection. In most cases, an antibody can only react to and bind one specific antigen; in some instances, however, antibodies may cross-react and bind more than one antigen. T ...
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Sloan-Kettering Institute
Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in the borough of Manhattan in New York City, founded in 1884 as the New York Cancer Hospital. MSKCC is one of 52 National Cancer Institute–designated Comprehensive Cancer Centers. Its main campus is located at 1275 York Avenue, between 67th and 68th streets, in Manhattan. According to U.S. News & World Report 2021-2022 Best Hospitals, Memorial Sloan Kettering Cancer Center (MSK) has been ranked as the number two hospital for cancer care in the nation. History New York Cancer Hospital (1884–1934) Memorial Hospital was founded on the Upper West Side of Manhattan in 1884 as the New York Cancer Hospital by a group that included John Jacob Astor III and his wife Charlotte. The hospital appointed as an attending surgeon William B. Coley, who pioneered an early form of immunotherapy to eradicate tumors. Rose Hawthorne, daughter of author Nathaniel Hawthorne, trained there in ...
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Roswell Park Comprehensive Cancer Center
Roswell Park Comprehensive Cancer Center is a cancer research and treatment center located in Buffalo, New York. Founded by surgeon Roswell Park in 1898, the center was the first in the United States to specifically focus on cancer research. The center is usually called Roswell Park in short form. The center, which conducts clinical research on cancer as well as the development new drugs, provides advanced treatment for all forms of adult and pediatric cancer, and serves as a member of the National Comprehensive Cancer Network. Roswell Park Comprehensive Cancer Center is currently the only upstate New York facility to hold the National Cancer Institute designation of "comprehensive cancer center". The Roswell Park campus, spread out in 15 separate buildings of approximately two million square feet, occupies on the Buffalo Niagara Medical Campus (BNMC) in downtown Buffalo, and includes of space equally distributed between clinical programs and research/education functions. A sep ...
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Herman Eisen
Herman Nathaniel Eisen (October 15, 1918 – November 2, 2014) was an American immunologist and cancer researcher. He served on the faculty at New York University School of Medicine in the early 1950s, became the Chief of Dermatology at the Washington University School of Medicine in 1955, and was a founding member of the MIT Center for Cancer Research (now called the Koch Institute for Integrative Cancer Research). Eisen retired and assumed professor emeritus status in 1989, but continued to be active as a researcher; he was working on a manuscript the day he died in 2014. Early life and education Eisen was born in Brooklyn, New York, in 1918, one of four children of Jewish immigrants from Eastern Europe. His undergraduate studies at New York University began in 1934 but were interrupted by a case of tuberculosis, which required him to withdraw from school for a year; he later recalled this as a key event in his life inspiring him to focus on intellectual activities. After gradu ...
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Arthur Silverstein
Arthur M. Silverstein is an American immunologist and science historian who has written extensively on the history of immunology. He is Professor Emeritus of Ophthalmic Immunology at the Johns Hopkins School of Medicine, where he spent 25 years on the faculty in the Department of Ophthalmology and was also affiliated with its Institute of the History of Medicine. Silverstein took a break during his Ph.D. studies at Ohio State University and worked as a technician in the laboratory of David Pressman, where he first became interested in the subject of immunology. He returned to his studies and received a Ph.D. in physical chemistry from Rensselaer Polytechnic Institute in 1954. After finishing, Silverstein entered military service and was assigned to the Armed Forces Institute of Pathology, where he found a mentor in then-Scientific Director Ernest Goodpasture and studied the development of the immune system. Silverstein ultimately spent around 10 years at the institute before jo ...
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Alfred Nisonoff
Alfred Nisonoff (1923–2001) was a 20th-century chemist who helped to experimentally determine the molecular structure of the antibody, and, as a result, made major contributions to the field of immunology. Nisonoff's monograph, “The Antibody Molecule,” was the most important and in-depth paper on the antibody during his time. Biography Nisonoff's parents immigrated from Hungary and Russia to New York City as teenagers. He was born in Corona, Queens on January 26, 1923. His parents moved the family to South River, New Jersey, where they operated a butcher shop and a grocery store throughout Alfred's childhood.Piehler, G. KurtAn Interview with Alfred Nisonoff, for the Rutgers Oral History Archives of World War II., Rutgers University, August 1, 1994. Accessed February 6, 2011. "AN: His first stores were butcher shops. He had the kosher butcher shop in South River, and that goes all the way back to when I was five or so. Yeah, I was born in Corona, Long Island, but, then, ...
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American Immunologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ...
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