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David Mervyn Blow
David Mervyn Blow (27 June 1931 – 8 June 2004) was an influential British biophysicist. He was best known for the development of X-ray crystallography, a technique used to determine the molecular structures of tens of thousands of biological molecules. This has been extremely important to the pharmaceutical industry. Early life and education Blow was born in Birmingham, England. He was educated at Kingswood School in Bath, Somerset and the University of Cambridge where he won a scholarship to Corpus Christi College, Cambridge. His PhD was awarded in 1958 for X-ray analysis of haemoglobin supervised by Max Perutz. Career and research Following graduation from Cambridge, Blow spent two years at the Massachusetts Institute of Technology (MIT) and the National Institutes of Health (NIH) funded by the Fulbright Foundation In 1954, he met Max Perutz; they began to study a new technique wherein X-rays would be passed through a protein sample. This eventually led to the creation o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Birmingham
Birmingham ( ) is a city and metropolitan borough in the metropolitan county of West Midlands in England. It is the second-largest city in the United Kingdom with a population of 1.145 million in the city proper, 2.92 million in the West Midlands metropolitan county, and approximately 4.3 million in the wider metropolitan area. It is the largest UK metropolitan area outside of London. Birmingham is known as the second city of the United Kingdom. Located in the West Midlands region of England, approximately from London, Birmingham is considered to be the social, cultural, financial and commercial centre of the Midlands. Distinctively, Birmingham only has small rivers flowing through it, mainly the River Tame and its tributaries River Rea and River Cole – one of the closest main rivers is the Severn, approximately west of the city centre. Historically a market town in Warwickshire in the medieval period, Birmingham grew during the 18th century during the Midla ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brian Matthews (biochemist)
Brian W. Matthews is a biochemist and biophysicist educated at the University of Adelaide, contributor to x-ray crystallographic methodology at the University of Cambridge, and since 1970 at the University of Oregon as Professor of Physics and HHMI investigator in the Institute of Molecular Biology. He created hundreds of mutants of T4 lysozyme (making it the commonest structure in the PDB), determined their structure by x-ray crystallography and measured their melting temperatures. Starting from questions about the basis of "temperature-sensitive" mutations, his work has explicated much about the general energetic and structural effects of mutations in proteins. He also solved early structures of the thermophilic bacterial enzyme thermolysin, the helix-turn-helix DNA-binding transcription factor lambda Cro repressor, and the light-antenna bacteriochlorophyll protein. Beyond his contributions to biochemistry, Matthews is also known in the machine learning community for the Mat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fulbright Foundation
The Fulbright Program, including the Fulbright–Hays Program, is one of several United States Cultural Exchange Programs with the goal of improving intercultural relations, cultural diplomacy, and intercultural competence between the people of the United States and other countries, through the exchange of persons, knowledge, and skills. Via the program, competitively-selected American citizens including students, scholars, teachers, professionals, scientists, and artists may receive scholarships or grants to study, conduct research, teach, or exercise their talents abroad; and citizens of other countries may qualify to do the same in the United States. The program was founded by United States Senator J. William Fulbright in 1946 and is considered to be one of the most widely recognized and prestigious scholarships in the world. The program provides approximately 8,000 grants annually – roughly 1,600 to U.S. students, 1,200 to U.S. scholars, 4,000 to foreign students, 900 to fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haemoglobin
Hemoglobin (haemoglobin BrE) (from the Greek word αἷμα, ''haîma'' 'blood' + Latin ''globus'' 'ball, sphere' + ''-in'') (), abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein present in red blood cells (erythrocytes) of almost all vertebrates (the exception being the fish family Channichthyidae) as well as the tissues of some invertebrates. Hemoglobin in blood carries oxygen from the respiratory organs (''e.g.'' lungs or gills) to the rest of the body (''i.e.'' tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power functions of an organism in the process called metabolism. A healthy individual human has 12to 20grams of hemoglobin in every 100mL of blood. In mammals, the chromoprotein makes up about 96% of the red blood cells' dry content (by weight), and around 35% of the total content (including water). Hemoglobin has an oxygen-binding capacity of 1.34mL O2 per gram, which increases the total blood oxygen ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Corpus Christi College, Cambridge
Corpus Christi College (full name: "The College of Corpus Christi and the Blessed Virgin Mary", often shortened to "Corpus"), is a constituent college of the University of Cambridge. From the late 14th century through to the early 19th century it was also commonly known as St Benet's College. The college is notable as the only one founded by Cambridge townspeople: it was established in 1352 by the Guild of Corpus Christi and the Guild of the Blessed Virgin Mary, making it the sixth-oldest college in Cambridge. With around 250 undergraduates and 200 postgraduates, it also has the second smallest student body of the traditional colleges of the University, after Peterhouse. The College has traditionally been one of the more academically successful colleges in the University of Cambridge. In the unofficial Tompkins Table, which ranks the colleges by the class of degrees obtained by their undergraduates, in 2012 Corpus was in third position, with 32.4% of its undergraduates achievi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bath, Somerset
Bath () is a city in the Bath and North East Somerset unitary area in the county of Somerset, England, known for and named after its Roman-built baths. At the 2021 Census, the population was 101,557. Bath is in the valley of the River Avon, west of London and southeast of Bristol. The city became a World Heritage Site in 1987, and was later added to the transnational World Heritage Site known as the "Great Spa Towns of Europe" in 2021. Bath is also the largest city and settlement in Somerset. The city became a spa with the Latin name ' ("the waters of Sulis") 60 AD when the Romans built baths and a temple in the valley of the River Avon, although hot springs were known even before then. Bath Abbey was founded in the 7th century and became a religious centre; the building was rebuilt in the 12th and 16th centuries. In the 17th century, claims were made for the curative properties of water from the springs, and Bath became popular as a spa town in the Georgian era. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physics Today
''Physics Today'' is the membership magazine of the American Institute of Physics. First published in May 1948, it is issued on a monthly schedule, and is provided to the members of ten physics societies, including the American Physical Society. It is also available to non-members as a paid annual subscription. The magazine informs readers about important developments in overview articles written by experts, shorter review articles written internally by staff, and also discusses issues and events of importance to the science community in politics, education, and other fields. The magazine provides a historical resource of events associated with physics. For example it discussed debunking the physics of the Star Wars program of the 1980s, and the state of physics in China and the Soviet Union during the 1950s and 1970s. According to the ''Journal Citation Reports'', the journal has a 2017 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmaceutical
A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in multiple ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the order of a physician, physician assistant, or qualified nurse) from over-the-counter drugs (those that consumers can order for themselves). Another key distinction is between traditional small molecule drugs, usually derived from chemical synthesis, and biopharmaceuticals, which include recombinant proteins, vaccines, blood products used therapeutically (such as IVIG), gene therapy, monoclonal antibodies and cell therapy (for instance, stem cell therapies) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecule
A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and biochemistry, the distinction from ions is dropped and ''molecule'' is often used when referring to polyatomic ions. A molecule may be homonuclear, that is, it consists of atoms of one chemical element, e.g. two atoms in the oxygen molecule (O2); or it may be heteronuclear, a chemical compound composed of more than one element, e.g. water (two hydrogen atoms and one oxygen atom; H2O). In the kinetic theory of gases, the term ''molecule'' is often used for any gaseous particle regardless of its composition. This relaxes the requirement that a molecule contains two or more atoms, since the noble gases are individual atoms. Atoms and complexes connected by non-covalent interactions, such as hydrogen bonds or ionic bonds, are typically not consid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biophysicist
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study Biology, biological phenomena. Biophysics covers all scales of biological organization, from Molecule, molecular to organismic and Population (biology), populations. Biophysical research shares significant overlap with biochemistry, molecular biology, physical chemistry, physiology, nanotechnology, bioengineering, computational biology, biomechanics, developmental biology and systems biology. The term ''biophysics'' was originally introduced by Karl Pearson in 1892.Roland Glaser. Biophysics: An Introduction'. Springer; 23 April 2012. . The term ''biophysics'' is also regularly used in academia to indicate the study of the Physical quantity, physical quantities (e.g. electric current, temperature, Stress (mechanics), stress, entropy) in biological systems. Other List of life sciences, biological sciences also perform research on the biophysical properties of living ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxford University Press
Oxford University Press (OUP) is the university press of the University of Oxford. It is the largest university press in the world, and its printing history dates back to the 1480s. Having been officially granted the legal right to print books by decree in 1586, it is the second oldest university press after Cambridge University Press. It is a department of the University of Oxford and is governed by a group of 15 academics known as the Delegates of the Press, who are appointed by the vice-chancellor of the University of Oxford. The Delegates of the Press are led by the Secretary to the Delegates, who serves as OUP's chief executive and as its major representative on other university bodies. Oxford University Press has had a similar governance structure since the 17th century. The press is located on Walton Street, Oxford, opposite Somerville College, in the inner suburb of Jericho. For the last 500 years, OUP has primarily focused on the publication of pedagogical texts and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biographical Memoirs Of Fellows Of The Royal Society
The ''Biographical Memoirs of Fellows of the Royal Society'' is an academic journal on the history of science published annually by the Royal Society. It publishes obituaries of Fellows of the Royal Society. It was established in 1932 as ''Obituary Notices of Fellows of the Royal Society'' and obtained its current title in 1955, with volume numbering restarting at 1. Prior to 1932, obituaries were published in the ''Proceedings of the Royal Society''. The memoirs are a significant historical record and most include a full bibliography of works by the subjects. The memoirs are often written by a scientist of the next generation, often one of the subject's own former students, or a close colleague. In many cases the author is also a Fellow. Notable biographies published in this journal include Albert Einstein, Alan Turing, Bertrand Russell, Claude Shannon, Clement Attlee, Ernst Mayr, and Erwin Schrödinger. Each year around 40 to 50 memoirs of deceased Fellows of the Royal Soci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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