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David Clayton
David George Clayton (born 13 June 1944), is a British statistician and epidemiologist. He is titular Professor of Biostatistics in the University of Cambridge and Wellcome Trust and Juvenile Diabetes Research Foundation Principal Research Fellow in the Diabetes and Inflammation Laboratory, where he chairs the statistics group. Clayton is an ISI highly cited researcher placing him in the top 250 most cited scientists in the mathematics world over the last 20 years. Career Clayton has worked in theoretical and applied statistics, both frequentist and Bayesian. With Norman Breslow he has published important work on generalized linear mixed models. Clayton was a pioneer in the application of MCMC methods to problems in biostatistics. More recently, he has worked in genetic epidemiology. Clayton read Natural Sciences at King's College, Cambridge and following this worked as a researcher in ergonomics and cybernetics. He then worked as a statistician at the London School of Hygie ...
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United Kingdom
The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It comprises England, Scotland, Wales and Northern Ireland. The United Kingdom includes the island of Great Britain, the north-eastern part of the island of Ireland, and many smaller islands within the British Isles. Northern Ireland shares a land border with the Republic of Ireland; otherwise, the United Kingdom is surrounded by the Atlantic Ocean, the North Sea, the English Channel, the Celtic Sea and the Irish Sea. The total area of the United Kingdom is , with an estimated 2020 population of more than 67 million people. The United Kingdom has evolved from a series of annexations, unions and separations of constituent countries over several hundred years. The Treaty of Union between the Kingdom of England (which included Wales, annexed in 1542) and the Kingdom of Scotland in 170 ...
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Bayesian Statistics
Bayesian statistics is a theory in the field of statistics based on the Bayesian interpretation of probability where probability expresses a ''degree of belief'' in an event. The degree of belief may be based on prior knowledge about the event, such as the results of previous experiments, or on personal beliefs about the event. This differs from a number of other interpretations of probability, such as the frequentist interpretation that views probability as the limit of the relative frequency of an event after many trials. Bayesian statistical methods use Bayes' theorem to compute and update probabilities after obtaining new data. Bayes' theorem describes the conditional probability of an event based on data as well as prior information or beliefs about the event or conditions related to the event. For example, in Bayesian inference, Bayes' theorem can be used to estimate the parameters of a probability distribution or statistical model. Since Bayesian statistics treats probabi ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Genome-wide Association Study
In genomics, a genome-wide association study (GWA study, or GWAS), also known as whole genome association study (WGA study, or WGAS), is an observational study of a genome-wide set of Single-nucleotide polymorphism, genetic variants in different individuals to see if any variant is associated with a trait. GWA studies typically focus on associations between single-nucleotide polymorphisms (SNPs) and traits like major human diseases, but can equally be applied to any other genetic variants and any other organisms. When applied to human data, GWA studies compare the DNA of participants having varying phenotypes for a particular trait or disease. These participants may be people with a disease (cases) and similar people without the disease (controls), or they may be people with different phenotypes for a particular trait, for example blood pressure. This approach is known as phenotype-first, in which the participants are classified first by their clinical manifestation(s), as oppose ...
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Wellcome Trust Case Control Consortium
The Wellcome Trust Case Control Consortium (abbreviated WTCCC) is a collaboration between fifty research groups in the United Kingdom in the field of human genetics. Established in 2005, the WTCCC aims to conduct genome-wide association studies (GWASs) to shed light on the genetic architecture of common human diseases. The founding chairman of the consortium was University of Oxford statistician Peter Donnelly. The consortium was funded by £9 million from the Wellcome Trust. According to the consortium's website, it has identified "approximately 90" new susceptibility loci for common human diseases. The consortium's initial goal was to conduct large GWASs for eight common human diseases: tuberculosis, coronary heart disease, type 1 diabetes, type 2 diabetes, rheumatoid arthritis, Crohn's disease and ulcerative colitis, bipolar disorder and hypertension. These GWASs included a total of 19,000 subjects, of whom 2,000 had one of the eight diseases and an additional 3,000 served a ...
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Committee Of Presidents Of Statistical Societies
The Committee of Presidents of Statistical Societies (COPSS) comprises the presidents, past presidents and presidents -elect of the following, primarily Northern American, professional societies of statisticians: * American Statistical Association * Institute of Mathematical Statistics * Eastern North American Region of the International Biometric Society * Western North American Region of the International Biometric Society * Statistical Society of Canada It also includes the president-elect-elect of Institute of Mathematical Statistics and the past-past-president of the Statistical Society of Canada. COPSS is responsible for granting the following awards: * The COPSS Presidents' Award for "an outstanding contribution to the profession of statistics" by a member of one of the constituent societies aged under 41 * The COPSS Distinguished Achievement Award and Lectureship for "achievement and scholarship in statistical science" that has made a "highly significant impact ... on scient ...
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Royal Statistical Society
The Royal Statistical Society (RSS) is an established statistical society. It has three main roles: a British learned society for statistics, a professional body for statisticians and a charity which promotes statistics for the public good. History The society was founded in 1834 as the Statistical Society of London, though a perhaps unrelated London Statistical Society was in existence at least as early as 1824. At that time there were many provincial statistics societies throughout Britain, but most have not survived. The Manchester Statistical Society (which is older than the LSS) is a notable exception. The associations were formed with the object of gathering information about society. The idea of statistics referred more to political knowledge rather than a series of methods. The members called themselves "statists" and the original aim was "...procuring, arranging and publishing facts to illustrate the condition and prospects of society" and the idea of interpretin ...
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University Of Leicester
, mottoeng = So that they may have life , established = , type = public research university , endowment = £20.0 million , budget = £326 million , chancellor = David Willetts , vice_chancellor = Nishan Canagarajah , head_label = Visitor , head = The King , academic_staff = 1,705 (2018/19) , administrative_staff = 2,205 (2018/19) , students = () , undergrad = () , postgrad = () , city = Leicester , country = England, UK , coordinates = , campus = Urban parkland , colours = , website = , logo = UniOfLeicesterLogo.svg , logo_size = 250px , affiliations = ACUAMBA EMUA EUA Sutton 30 M5 UniversitiesUniversities UK The University of Leicester ( ) is a public research university based in Leicester, England. The main campus is south of the city centre, adjacent to Victoria Park. The university's predecessor, University College, Leicester, gained university status in 1957. The university had an income of £323.1 million in 2019/20, of which £5 ...
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Cybernetics
Cybernetics is a wide-ranging field concerned with circular causality, such as feedback, in regulatory and purposive systems. Cybernetics is named after an example of circular causal feedback, that of steering a ship, where the helmsperson maintains a steady course in a changing environment by adjusting their steering in continual response to the effect it is observed as having. Cybernetics is concerned with circular causal processes such as steering however they are embodied,Ashby, W. R. (1956). An introduction to cybernetics. London: Chapman & Hall, p. 1. including in ecological, technological, biological, cognitive, and social systems, and in the context of practical activities such as designing, learning, managing, conversation, and the practice of cybernetics itself. Cybernetics' transdisciplinary and "antidisciplinary" character has meant that it intersects with a number of other fields, leading to it having both wide influence and diverse interpretations. Cybernetics ...
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Ergonomics
Human factors and ergonomics (commonly referred to as human factors) is the application of psychological and physiological principles to the engineering and design of products, processes, and systems. Four primary goals of human factors learning are to reduce human error, increase productivity, and enhance safety, system availability, and comfort with a specific focus on the interaction between the human and the engineered system. The field is a combination of numerous disciplines, such as psychology, sociology, engineering, biomechanics, industrial design, physiology, anthropometry, interaction design, visual design, user experience, and user interface design. Human factors research employs methods and approaches from these and other knowledge disciplines to study human behavior and generate data relevant to the four primary goals above. In studying and sharing learning on the design of equipment, devices, and processes that fit the human body and its cognitive abilities, t ...
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Natural Sciences
Natural science is one of the branches of science concerned with the description, understanding and prediction of natural phenomena, based on empirical evidence from observation and experimentation. Mechanisms such as peer review and repeatability of findings are used to try to ensure the validity of scientific advances. Natural science can be divided into two main branches: life science and physical science. Life science is alternatively known as biology, and physical science is subdivided into branches: physics, chemistry, earth science, and astronomy. These branches of natural science may be further divided into more specialized branches (also known as fields). As empirical sciences, natural sciences use tools from the formal sciences, such as mathematics and logic, converting information about nature into measurements which can be explained as clear statements of the " laws of nature". Modern natural science succeeded more classical approaches to natural philosophy, ...
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Genetic Epidemiology
Genetic epidemiology is the study of the role of genetic factors in determining health and disease in families and in populations, and the interplay of such genetic factors with environmental factors. Genetic epidemiology seeks to derive a statistical and quantitative analysis of how genetics work in large groups. Definition The use of the term ''Genetic epidemiology'' emerged in the mid-1980s as a new scientific field. In formal language, genetic epidemiology was defined by Newton Morton, one of the pioneers of the field, as "a science which deals with the etiology, distribution, and control of disease in groups of relatives and with inherited causes of disease in populations". It is closely allied to both molecular epidemiology and statistical genetics, but these overlapping fields each have distinct emphases, societies and journals. One definition of the field closely follows that of behavior genetics, defining genetic epidemiology as "the scientific discipline that deals w ...
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