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Daniel Von Hoff
Daniel D. Von Hoff is the physician in chief and director of translational research at Translational Genomics Research Institute (TGen), and current Virginia G. Piper Distinguished Chair for Innovative Cancer Research at HonorHealth Clinical Research Institute. He is also a professor of medicine at the Mayo Clinic and medical director of research as well as chief scientific officer at US Oncology. He is most notable for his work in targeted therapies for the treatment of cancer. He led the development of gemcitabine, and has several drugs in development. Education Von Hoff received his bachelor's degree from Carroll College, and his MD from Columbia University College of Physicians and Surgeons in 1973. He did a residency in internal medicine at UC San Francisco, followed by a fellowship in oncology at the National Cancer Institute. Career After his fellowship, Von Hoff joined the faculty at University of Texas Health Science Center, San Antonio (UTHSCSA) as a professor of m ...
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DVH Headshot
DVH may refer to *Darent Valley Hospital, an acute district general hospital in Dartford, Kent, England * Desert Valley Hospital * Dose-volume histogram *Dove Holes railway station Dove Holes railway station serves the village of Dove Holes, Derbyshire, England. The station is on the Buxton line between Manchester Piccadilly and Buxton; it is situated south-east of Piccadilly. It is managed and served by Northern Trains ..., Derbyshire, England (National Rail station code) See also * DVHS (other) {{Disambig ...
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Irinotecan
Irinotecan, sold under the brand name Camptosar among others, is a medication used to treat colon cancer, and small cell lung cancer. For colon cancer it is used either alone or with fluorouracil. For small cell lung cancer it is used with cisplatin. It is given intravenously. Common side effects include diarrhea, vomiting, bone marrow suppression, hair loss, shortness of breath, and fever. Other severe side effects include blood clots, colon inflammation, and allergic reactions. Those with two copies of the UGT1A1*28 gene variant are at higher risk for side effects. Use during pregnancy can result in harm to the baby. Irinotecan is a topoisomerase inhibitor—it blocks the topoisomerase I enzyme, resulting in DNA damage and cell death. Irinotecan was approved for medical use in the United States in 1996. It is on the World Health Organization's List of Essential Medicines. It is made from the natural compound camptothecin which is found in the Chinese ornamental tree ''Campt ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Fellows Of The AACR Academy
Fellows may refer to Fellow, in plural form. Fellows or Fellowes may also refer to: Places * Fellows, California, USA * Fellows, Wisconsin, ghost town, USA Other uses * Fellows Auctioneers, established in 1876. * Fellowes, Inc., manufacturer of workspace products *Fellows, a partner in the firm of English canal carriers, Fellows Morton & Clayton * Fellows (surname) See also *North Fellows Historic District The North Fellows Historic District is a historic district located in Ottumwa, Iowa, United States. The city experienced a housing boom after World War II. This north side neighborhood of single-family brick homes built between 1945 and 195 ..., listed on the National Register of Historic Places in Wapello County, Iowa * Justice Fellows (other) {{disambiguation ...
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American Oncologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ...
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AACR Academy
The American Association for Cancer Research elects classes of fellows to recognize influential scientists in the field of cancer research. Six fellows were appointed to Vice President Biden’s Cancer Moonshot Initiative Blue Ribbon Panel. Several are members of the National Academy of Sciences, several have won a Lasker Award, several have won a Nobel Prize, several are HHMI The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fi ... Investigators, and several are past presidents of the AACR. References {{Reflist American oncologists Biology awards ...
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American Society Of Clinical Oncology
The American Society of Clinical Oncology (ASCO) is a professional organization representing physicians of all oncology sub-specialties who care for people with cancer. Founded in 1964 by Fred Ansfield, Harry Bisel, Herman Freckman, Arnoldus Goudsmit, Robert Talley, William Wilson, and Jane C. Wright, it has nearly 45,000 members worldwide. Physician education ASCO offers educational resources for cancer physicians and other health care professionals of clinical oncology. These include scientific meetings, educational conferences, professional workshops, and special symposia on issues of particular relevance and importance to oncologists and researchers. It also produced the patient information website, Cancer.Net. It publishes numerous journals, books, newsletters, and online and multimedia resources; it publishes the ''Journal of Clinical Oncology The ''Journal of Clinical Oncology'' is a peer-reviewed medical journal published 3 times a month by the Lippincott Williams ...
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Dana Farber Cancer Institute
Dana may refer to: People Given name * Dana (given name) Surname * Dana (surname) * Dana family of Cambridge, Massachusetts ** James Dwight Dana (1813–1895), scientist, zoological author abbreviation Dana Nickname or stage name * Dana International, stage name of singer Sharon Cohen * Dana Shum, the Shaw Brothers Hong Kong actress from 1973 to 1979 * Dana, stage name of Dana Rosemary Scallon (born 1951), Irish singer and former politician * Dana (South Korean singer) (born 1986), South Korean pop singer Places Ancient world * Ancient Dana or Tyana in Cappadocia, capital of a Neo-Hittite kingdom in the 1st millennium BC * Ancient Dana possibly associated with Tynna in Cappadocia Canada * CFS Dana, a former military radar installation in Saskatchewan, Canada * Dana Lake, a lake in Eeyou Istchee Baie-James, Quebec, Canada Ethiopia * Dana, Ethiopia, a village Iran * Dana County, an administrative subdivision of Iran * Dana Rural District, an administrative subdi ...
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American Association For Cancer Research
The American Association for Cancer Research (AACR) is the world's oldest and largest professional association related to cancer research. Based in Philadelphia, the AACR focuses on all aspects of cancer research, including basic, clinical, and translational research into the etiology, prevention, diagnosis, and treatment of cancer. Founded in 1907 by 11 physicians and scientists, the organization now has more than 52,000 members in 130 countries and territories. The mission of the AACR is to prevent and cure cancer through research, education, communication, collaboration, science policy and advocacy, and funding for cancer research. History The AACR was founded on May 7, 1907 in Washington, DC as the "Association for Cancer Research" by a group of scientists consisting of four surgeons, five pathologists, and two biochemists. The founding members were Silas P. Beebe, George H. A. Clowes, William Coley, James Ewing, Harvey R. Gaylord, Robert B. Greenough, J. Collins War ...
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American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal of ...
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American College Of Physicians
The American College of Physicians (ACP) is a national organization of internists, who specialize in the diagnosis, treatment, and care of adults.Sokanu "What is an Internist?" Retrieved October 20, 2014 With 161,000 members, ACP is the largest medical-specialty organization and second-largest physician group in the United States, after the American Medical Association.Osmosis "Prep for the Medicine Shelf". Retrieved October 20, 2014 Its flagship journal, the ''Annals of Internal Medicine'', is considered one of the five top medical journals in the United States and Britain. Mission and history Founded in 1915, ACP's stated mission is to "enhance the quality and effectiveness of health care by fostering excellence and professionalism in the practice of medicine." In 1998, it merged with the American Society of Internal Medicine (ASIM). ASIM's focus on the economic, political, and social aspects of medical care both enlarged and complemented its mission. Known as ACP-ASIM from ...
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Vismodegib
Vismodegib (trade name Erivedge ) is a drug for the treatment of basal-cell carcinoma (BCC). The approval of vismodegib on January 30, 2012, represents the first Hedgehog signaling pathway targeting agent to gain U.S. Food and Drug Administration (FDA) approval. The drug is also undergoing clinical trials for metastatic colorectal cancer, small-cell lung cancer, advanced stomach cancer, pancreatic cancer, medulloblastoma and chondrosarcoma . The drug was developed by the biotechnology/pharmaceutical company Genentech. Indication Vismodegib is indicated for patients with basal-cell carcinoma (BCC) which has metastasized to other parts of the body, relapsed after surgery, or cannot be treated with surgery or radiation. Mechanism of action The substance acts as a cyclopamine-competitive antagonist of the smoothened receptor (SMO) which is part of the Hedgehog signaling pathway. SMO inhibition causes the transcription factors GLI1 and GLI2 to remain inactive, which prevents t ...
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