Daniel Jobst Müller
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Daniel Jobst Müller
Daniel Jobst Müller (born 22 March 1965) is a German scientist and Professor of Biophysics at ETH Zürich. He is known for work on Single-molecule experiment, single molecule and cell biophysics, bionanotechnology, and membrane proteins. Education Müller was educated in physics at the University of Technology Berlin and the Hahn-Meitner-Institute in Berlin, Germany. He did his PhD research at University of Basel with Andreas Engel and Forschungszentrum Jülich with Goerg Büldt. He was awarded his PhD in 1997 in Life Sciences at the University of Basel. Research career In 2000, Müller became a group leader at the Max Planck Institute for Cell Biology and Genetics in Dresden, Germany. Shortly after, he was appointed full Professor at Technical University of Dresden in 2002, where he acted as director from 2003 to 2005. His research group initially focused on single molecule biophysics before branching out into wider topics such as cell biophysics, cell adhesion, and cell mechan ...
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Bad Wimpfen
Bad Wimpfen () is a historic spa town in the district of Heilbronn in the Baden-Württemberg region of southern Germany. It lies north of the city of Heilbronn, on the river Neckar. Geography Bad Wimpfen is located on the west bank of the River Neckar, around north of Heilbronn. The town is divided into two parts: the older ''Wimpfen im Tal'' (Lower Wimpfen/ literally Wimpfen in the valley) situated on the Neckar, and ''Wimpfen am Berg'' (Upper Wimpfen/ literally Wimpfen on the hill) containing the town centre. Besides the town itself, the village ''Hohenstadt'' also belongs to Bad Wimpfen. Neighbouring municipalities Neighbouring town and municipalities of Bad Wimpfen are (clockwise from the south): ''Heilbronn'', ''Bad Rappenau'', Offenau, '' Bad Friedrichshall'', Untereisesheim and '' Neckarsulm''. History First settlement by the Celts The first traces of settlement at Bad Wimpfen date from the Neolithic and the Bronze Age. An old trade road running from France f ...
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Forschungszentrum Jülich
Forschungszentrum Jülich (FZJ; “Jülich Research Centre”) is a German national research institution that pursues interdisciplinary research in the fields of energy, information, and bioeconomy. It operates a broad range of research infrastructures like supercomputers, an atmospheric simulation chamber, electron microscopes, a particle accelerator, cleanrooms for nanotechnology, among other things. Current research priorities include the structural change in the Rhineland lignite-mining region, hydrogen, and quantum technologies. As a member of the Helmholtz Association with roughly 6,800 employees in ten institutes and 80 subinstitutes, Jülich is one of the largest research institutions in Europe. Forschungszentrum Jülich's headquarters are located between the cities of Aachen, Cologne, and Düsseldorf on the outskirts of the North Rhine-Westphalian town of Jülich. FZJ has 15 branch offices in Germany and abroad, including eight sites at European and international ne ...
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Living People
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German Molecular Biologists
German(s) may refer to: * Germany, the country of the Germans and German things **Germania (Roman era) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizenship in Germany, see also German nationality law **Germanic peoples (Roman era) *German diaspora * German language * German cuisine, traditional foods of Germany People * German (given name) * German (surname) * Germán, a Spanish name Places * German (parish), Isle of Man * German, Albania, or Gërmej * German, Bulgaria * German, Iran * German, North Macedonia * German, New York, U.S. * Agios Germanos, Greece Other uses * German (mythology), a South Slavic mythological being * Germans (band), a Canadian rock band * "German" (song), a 2019 song by No Money Enterprise * ''The German'', a 2008 short film * "The Germans", an episode of ''Fawlty Towers'' * ''The German'', a nickname for Congolese rebel André Kisase Ngandu See also * Germanic (disambiguatio ...
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Force Spectroscopy
Force spectroscopy is a set of techniques for the study of the interactions and the binding forces between individual molecules. These methods can be used to measure the mechanical properties of single polymer molecules or proteins, or individual chemical bonds. The name "force spectroscopy", although widely used in the scientific community, is somewhat misleading, because there is no true matter-radiation interaction. Techniques that can be used to perform force spectroscopy include atomic force microscopy, optical tweezers, magnetic tweezers, acoustic force spectroscopy, microneedles, and biomembranes. Force spectroscopy measures the behavior of a molecule under stretching or torsional mechanical force. In this way a great deal has been learned in recent years about the mechanochemical coupling in the enzymes responsible for muscle contraction, transport in the cell, energy generation (F1-ATPase), DNA replication and transcription (polymerases), DNA unknotting and unwinding (to ...
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Switzerland
Switzerland, officially the Swiss Confederation, is a landlocked country located in west-central Europe. It is bordered by Italy to the south, France to the west, Germany to the north, and Austria and Liechtenstein to the east. Switzerland is geographically divided among the Swiss Plateau, the Swiss Alps, Alps and the Jura Mountains, Jura; the Alps occupy the greater part of the territory, whereas most of the country's Demographics of Switzerland, 9 million people are concentrated on the plateau, which hosts List of cities in Switzerland, its largest cities and economic centres, including Zurich, Geneva, and Lausanne. Switzerland is a federal republic composed of Cantons of Switzerland, 26 cantons, with federal authorities based in Bern. It has four main linguistic and cultural regions: German, French, Italian and Romansh language, Romansh. Although most Swiss are German-speaking, national identity is fairly cohesive, being rooted in a common historical background, shared ...
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Basel
Basel ( ; ), also known as Basle ( ), ; ; ; . is a city in northwestern Switzerland on the river Rhine (at the transition from the High Rhine, High to the Upper Rhine). Basel is Switzerland's List of cities in Switzerland, third-most-populous city (after Zurich and Geneva), with 177,595 inhabitants within the city municipality limits. The official language of Basel is Swiss Standard German and the main spoken language is the local Basel German dialect. Basel is commonly considered to be the cultural capital of Switzerland and the city is famous for its many Museums in Basel, museums, including the Kunstmuseum Basel, Kunstmuseum, which is the first collection of art accessible to the public in the world (1661) and the largest museum of Swiss art, art in Switzerland, the Fondation Beyeler (located in Riehen), the Museum Tinguely and the Museum of Contemporary Art (Basel), Museum of Contemporary Art, which is the first public museum of contemporary art in Europe. Forty museums ...
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ETH Zurich
ETH Zurich (; ) is a public university in Zurich, Switzerland. Founded in 1854 with the stated mission to educate engineers and scientists, the university focuses primarily on science, technology, engineering, and mathematics. ETH Zurich ranks among Europe's best universities. Like its sister institution École Polytechnique Fédérale de Lausanne, EPFL, ETH Zurich is part of the ETH Domain, Swiss Federal Institutes of Technology Domain, a consortium of universities and research institutes under the Swiss Federal Department of Economic Affairs, Education and Research. , ETH Zurich enrolled 25,380 students from over 120 countries, of which 4,425 were pursuing doctoral degrees. Students, faculty, and researchers affiliated with ETH Zurich include 22 Nobel Prize, Nobel laureates, two Fields Medalists, three Pritzker Architecture Prize, Pritzker Prize winners, and one Turing Award, Turing Award recipient, including Albert Einstein and John von Neumann. It is a founding member o ...
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Cell Mechanics
Cell mechanics is a sub-field of biophysics that focuses on the mechanical properties and behavior of living cells and how it relates to cell function. It encompasses aspects of cell biophysics, biomechanics, soft matter physics and rheology, mechanobiology and cell biology. Eukaryotic Eukaryotic cells are cells that consist of membrane-bound organelles, a membrane-bound nucleus, and more than one linear chromosome. Being much more complex than prokaryotic cells, cells without a true nucleus, eukaryotes must protect its organelles from outside forces. Plant Plant cell mechanics combines principles of biomechanics and mechanobiology to investigate the growth and shaping of the plant cells. Plant cells, similar to animal cells, respond to externally applied forces, such as by reorganization of their cytoskeletal network. The presence of a considerably rigid extracellular matrix, the cell wall, however, bestows the plant cells with a set of particular properties. Mainly, the ...
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Cell Adhesion
Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as Cell_junction, cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix (ECM), a gel-like structure containing molecules released by cells into spaces between them. Cells adhesion occurs from the interactions between cell adhesion molecules, cell-adhesion molecules (CAMs), transmembrane proteins located on the cell surface. Cell adhesion links cells in different ways and can be involved in signal transduction for cells to detect and respond to changes in the surroundings. Other cellular processes regulated by cell adhesion include cell migration and tissue development in multicellular organisms. Alterations in cell adhesion can disrupt important cellular processes and lead to a variety of diseases, including cancer and arthrit ...
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Biophysics
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. Biophysical research shares significant overlap with biochemistry, molecular biology, physical chemistry, physiology, nanotechnology, bioengineering, computational biology, biomechanics, developmental biology and systems biology. The term ''biophysics'' was originally introduced by Karl Pearson in 1892. Roland Glaser. Biophysics: An Introduction'. Springer; 23 April 2012. . The term ''biophysics'' is also regularly used in academia to indicate the study of the physical quantities (e.g. electric current, temperature, stress, entropy) in biological systems. Other biological sciences also perform research on the biophysical properties of living organisms including molecular biology, cell biology, chemical biology, and bioche ...
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Technical University Of Dresden
TU Dresden (for , abbreviated as TUD), also as the Dresden University of Technology, is a public research university in Dresden, Germany. It is the largest institute of higher education in the city of Dresden, the largest university in Saxony and one of the 10 largest universities in Germany with 32,389 students . The name Technische Universität Dresden has only been used since 1961; the history of the university, however, goes back nearly 200 years to 1828. This makes it one of the oldest colleges of technology in Germany, and one of the country's oldest universities, which in German today refers to institutes of higher education that cover the entire curriculum. The university is a member of TU9, a consortium of the nine leading German Institutes of Technology. The university is one of eleven German universities which succeeded in the Excellence Initiative in 2012, thus getting the title of a "University of Excellence". The TU Dresden succeeded in all three rounds of the Ge ...
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