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Cytoscape
Cytoscape is an open source bioinformatics software platform for visualizing molecular interaction networks and integrating with gene expression profiles and other state data. Additional features are available as plugins. Plugins are available for network and molecular profiling analyses, new layouts, additional file format support and connection with databases and searching in large networks. Plugins may be developed using the Cytoscape open Java software architecture by anyone and plugin community development is encouraged. Cytoscape also has a JavaScript-centric sister project nameCytoscape.jsthat can be used to analyse and visualise graphs in JavaScript environments, like a browser. History Cytoscape was originally created at the Institute of Systems Biology in Seattle in 2002. Now, it is developed by an international consortium of open source developers. Cytoscape was initially made public in July, 2002 (v0.8); the second release (v0.9) was in November, 2002, and v1.0 w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cytoscape Network Visualization1
Cytoscape is an open source bioinformatics software platform for visualizing molecular interaction networks and integrating with gene expression profiles and other state data. Additional features are available as plugins. Plugins are available for network and molecular profiling analyses, new layouts, additional file format support and connection with databases and searching in large networks. Plugins may be developed using the Cytoscape open Java software architecture by anyone and plugin community development is encouraged. Cytoscape also has a JavaScript-centric sister project nameCytoscape.jsthat can be used to analyse and visualise graphs in JavaScript environments, like a browser. History Cytoscape was originally created at the Institute of Systems Biology in Seattle in 2002. Now, it is developed by an international consortium of open source developers. Cytoscape was initially made public in July, 2002 (v0.8); the second release (v0.9) was in November, 2002, and v1.0 w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Graph Modelling Language
Graph Modeling Language (GML) is a hierarchical ASCII-based file format for describing graphs. It has been also named ''Graph Meta Language''. Example A simple graph in GML format: graph comment "This is a sample graph" directed 1 id 42 label "Hello, I am a graph" node [ id 1 label "node 1" thisIsASampleAttribute 42 node [ id 2 label "node 2" thisIsASampleAttribute 43 ] node [ id 3 label "node 3" thisIsASampleAttribute 44 ] edge [ source 1 target 2 label "Edge from node 1 to node 2" ] edge [ source 2 target 3 label "Edge from node 2 to node 3" ] edge source 3 target 1 label "Edge from node 3 to node 1" ] Applications supporting GML * Cytoscape, an open source bioinformatics software platform for visualizing molecular interaction networks, loads and save previously-constructed interaction networks in GML. * igraph, an open source network analysis library with interfaces to multiple programming languages. * Gephi, an open sour ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
XGMML
XGMML (the eXtensible Graph Markup and Modeling Language) is an XML application based on GML which is used for graph description. Technically, while GML is not related to XML nor SGML, XGMML is an XML application that is so designed that there's a 1:1 relation towards GML for trivial conversion between the two formats. Applications supporting XGMML * Cytoscape, an open source bioinformatics software platform for visualizing molecular interaction networks, loads and saves networks and node/edge attributes in XGMML * Biomax BioXM Knowledge Management Environment, a customizable knowledge management system for life sciences, supports export of semantic network A semantic network, or frame network is a knowledge base that represents semantic relations between concepts in a network. This is often used as a form of knowledge representation. It is a directed or undirected graph consisting of vertices, ... graphs as XGMML files * JNets, a network visualization and analysis too ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Graph Drawing Software
Graph drawing is an area of mathematics and computer science combining methods from geometric graph theory and information visualization to derive two-dimensional depictions of graphs arising from applications such as social network analysis, cartography, linguistics, and bioinformatics. A drawing of a graph or network diagram is a pictorial representation of the vertices and edges of a graph. This drawing should not be confused with the graph itself: very different layouts can correspond to the same graph., p. 6. In the abstract, all that matters is which pairs of vertices are connected by edges. In the concrete, however, the arrangement of these vertices and edges within a drawing affects its understandability, usability, fabrication cost, and aesthetics. The problem gets worse if the graph changes over time by adding and deleting edges (dynamic graph drawing) and the goal is to preserve the user's mental map. Graphical conventions Graphs are frequently drawn as node–link ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Graph Drawing
Graph drawing is an area of mathematics and computer science combining methods from geometric graph theory and information visualization to derive two-dimensional depictions of graph (discrete mathematics), graphs arising from applications such as social network analysis, cartography, linguistics, and bioinformatics. A drawing of a graph or network diagram is a pictorial representation of the vertex (graph theory), vertices and edge (graph theory), edges of a graph. This drawing should not be confused with the graph itself: very different layouts can correspond to the same graph., p. 6. In the abstract, all that matters is which pairs of vertices are connected by edges. In the concrete, however, the arrangement of these vertices and edges within a drawing affects its understandability, usability, fabrication cost, and aesthetics. The problem gets worse if the graph changes over time by adding and deleting edges (dynamic graph drawing) and the goal is to preserve the user's menta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Force-based Algorithms (graph Drawing)
Force-directed graph drawing algorithms are a class of algorithms for drawing graphs in an aesthetically-pleasing way. Their purpose is to position the nodes of a graph in two-dimensional or three-dimensional space so that all the edges are of more or less equal length and there are as few crossing edges as possible, by assigning forces among the set of edges and the set of nodes, based on their relative positions, and then using these forces either to simulate the motion of the edges and nodes or to minimize their energy. While graph drawing can be a difficult problem, force-directed algorithms, being physical simulations, usually require no special knowledge about graph theory such as planarity. Forces Force-directed graph drawing algorithms assign forces among the set of edges and the set of nodes of a graph drawing. Typically, spring-like attractive forces based on Hooke's law are used to attract pairs of endpoints of the graph's edges towards each other, while simultaneousl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mathematical And Theoretical Biology
Mathematical and theoretical biology, or biomathematics, is a branch of biology which employs theoretical analysis, mathematical models and abstractions of the living organisms to investigate the principles that govern the structure, development and behavior of the systems, as opposed to experimental biology which deals with the conduction of experiments to prove and validate the scientific theories. The field is sometimes called mathematical biology or biomathematics to stress the mathematical side, or theoretical biology to stress the biological side. Theoretical biology focuses more on the development of theoretical principles for biology while mathematical biology focuses on the use of mathematical tools to study biological systems, even though the two terms are sometimes interchanged. Mathematical biology aims at the mathematical representation and modeling of biological processes, using techniques and tools of applied mathematics. It can be useful in both theoretical and prac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Systems Biology
Systems biology is the computational modeling, computational and mathematical analysis and modeling of complex biological systems. It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionist, reductionism) to biological research. Particularly from the year 2000 onwards, the concept has been used widely in biology in a variety of contexts. The Human Genome Project is an example of applied systems thinking in biology which has led to new, collaborative ways of working on problems in the biological field of genetics. One of the aims of systems biology is to model and discover emergent property, emergent properties, properties of cell (biology), cells, tissue (biology), tissues and organisms functioning as a system whose theoretical description is only possible using techniques of systems biology. These typically involve metabolic networks or cell ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioinformatics Software
The list of bioinformatics software tools can be split up according to the license used: *List of proprietary bioinformatics software *List of open-source bioinformatics software Alternatively, here is a categorization according to the respective bioinformatics subfield specialized on: *Sequence analysis software **List of sequence alignment software ** List of alignment visualization software **Alignment-free sequence analysis **De novo sequence assemblers **List of gene prediction software ** List of disorder prediction software ** List of Protein subcellular localization prediction tools **List of phylogenetics software **List of phylogenetic tree visualization software ** :Metagenomics_software *Structural biology software **List of molecular graphics systems **List of protein-ligand docking software **List of RNA structure prediction software **List of software for protein model error verification **List of protein secondary structure prediction programs **List of protein struct ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein–protein Interaction Prediction
Protein–protein interaction prediction is a field combining bioinformatics and structural biology in an attempt to identify and catalog physical interactions between pairs or groups of proteins. Understanding protein–protein interactions is important for the investigation of intracellular signaling pathways, modelling of protein complex structures and for gaining insights into various biochemical processes. ''Experimentally'', physical interactions between pairs of proteins can be inferred from a variety of techniques, including yeast two-hybrid systems, protein-fragment complementation assays (PCA), affinity purification/mass spectrometry, protein microarrays, fluorescence resonance energy transfer (FRET), and Microscale Thermophoresis (MST). Efforts to experimentally determine the interactome of numerous species are ongoing. Experimentally determined interactions usually provide the basis for ''computational methods'' to predict interactions, e.g. using homologous protein se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
JavaScript Library
A JavaScript library is a library of pre-written JavaScript code that allows for easier development of JavaScript-based applications, especially for AJAX and other web-centric technologies. Libraries With the expanded demands for JavaScript, an easier means for programmers to develop such dynamic interfaces was needed. Thus, JavaScript libraries and JavaScript widget libraries were developed, allowing for developers to concentrate more upon more distinctive applications of Ajax. This has led to other companies and groups, such as Microsoft and Yahoo! developing their own JavaScript-based user interface libraries, which find their way into the web applications developed by these companies. Some JavaScript libraries allow for easier integration of JavaScript with other web development technologies, such as CSS, PHP, Ruby, and Java. While others provide utilities, often in the form of JavaScript functions, to make repetitive and complex tasks less taxing. Many libraries include code t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
JavaScript Framework
A web framework (WF) or web application framework (WAF) is a software framework that is designed to support the development of web applications including web services, web resources, and web APIs. Web frameworks provide a standard way to build and deploy web applications on the World Wide Web. Web frameworks aim to automate the overhead associated with common activities performed in web development. For example, many web frameworks provide libraries for database access, templating frameworks, and session management, and they often promote code reuse. Although they often target development of dynamic web sites, they are also applicable to static websites. History As the design of the World Wide Web was not inherently dynamic, early hypertext consisted of hand-coded HTML text files that were published on web servers. Any modifications to published pages needed to be performed by the pages' author. In 1993, the Common Gateway Interface (CGI) standard was introduced for interfacin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
