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Coronavirus 3′ Stem-loop II-like Motif (s2m)
The Coronavirus 3′ stem-loop II-like motif (also known as s2m) is a secondary structure motif identified in the 3′ UTR, 3′ untranslated region (3′UTR) of astrovirus, coronavirus and equine rhinovirus genomes. Its function is unknown, but various viral 3′ UTR regions have been found to play roles in viral replication and packaging. This motif appears to be conserved in both nucleotide sequence and secondary structure folding indicating a strong evolutionary selection for its Conserved sequence, conservation. The presence of this conserved motif in different viral families is suggested to be the result of at least two separate Genetic recombination, recombination events. To date s2m has been described in four families of positive sense single-stranded RNA viruses; ''Astrovirus, Astroviridae'', ''Caliciviridae'', ''Picornavirus, Picornaviridae'' and ''Coronavirus, Coronaviridae''. The viruses that contain s2m can infect a wide range of higher vertebrates, including birds, b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Secondary Structure
Protein secondary structure is the three dimensional conformational isomerism, form of ''local segments'' of proteins. The two most common Protein structure#Secondary structure, secondary structural elements are alpha helix, alpha helices and beta sheets, though beta turns and omega loops occur as well. Secondary structure elements typically spontaneously form as an intermediate before the protein protein folding, folds into its three dimensional protein tertiary structure, tertiary structure. Secondary structure is formally defined by the pattern of hydrogen bonds between the Amine, amino hydrogen and carboxyl oxygen atoms in the peptide backbone chain, backbone. Secondary structure may alternatively be defined based on the regular pattern of backbone Dihedral angle#Dihedral angles of proteins, dihedral angles in a particular region of the Ramachandran plot regardless of whether it has the correct hydrogen bonds. The concept of secondary structure was first introduced by Kaj Ulrik ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
