|
Coralmyn
Coralmyn, also called Polyvalent Anti-coral Fabotherapic, is a polyclonal antivenom F(ab')2 used to treat venomous bites in mammals from the eastern coral snake and the Texas coral snake ''Micrurus tener'', commonly known as the Texas coral snake, is a species of venomous snake in the family Elapidae. The species is endemic to the southern United States and northeastern and central Mexico. Five subspecies are recognized as bei .... It was manufactured in Mexico by the '' Instituto Bioclon'', and was only obtainable in the United States with an application of an USDA importer's permit and state license. Because of the relative rarity of such bites, the remaining United States reserve of this medicine has been restricted to human-only use and is set to expire in 2017. Treatment of small animals (dogs and cats) with this product following accidental bites had proven highly effective in preventing shock and death. References {{reflist Antitoxins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antivenom
Antivenom, also known as antivenin, venom antiserum, and antivenom immunoglobulin, is a specific treatment for envenomation. It is composed of antibodies and used to treat certain venomous bites and stings. Antivenoms are recommended only if there is significant toxicity or a high risk of toxicity. The specific antivenom needed depends on the species involved. It is given by injection. Side effects may be severe. They include serum sickness, shortness of breath, and allergic reactions including anaphylaxis. Antivenom is traditionally made by collecting venom from the relevant animal and injecting small amounts of it into a domestic animal. The antibodies that form are then collected from the domestic animal's blood and purified. Versions are available for spider bites, snake bites, fish stings, and scorpion stings. Due to the high cost of producing antibody-based antivenoms and their short shelf lives when not refrigerated, alternative methods of production of antivenoms ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Instituto Bioclon
The Instituto Bioclon S.A. de C.V. (Bioclon Institute) was formed in 1990 to research and develop F(ab’)2 antivenoms. On May 6, 2015 they received approval from the FDA to commercialize Anavip becoming their second drug approved by the FDA after ANASCORP. Both are commercialized in the US by Rare Disease Therapeutics, Inc. The company is performing clinical trials to get approval for a third drug, ANALATRO, designed to treat black widow spider envenomation. Operations The Instituto Bioclon is located in Mexico City, Mexico and has a Certificación Internacional de Buenas Prácticas de Manufactura (International Certificate for Good Manufacturing Practices) which was granted to Bioclon by the , (INVIMA) (National Food and Drug Monitoring Institute), of the Ministry of Health and Social Protection of Colombia, as well as by COFEPRIS, in Mexico. Products * Anavip – timber rattlesnake antivenom *Coralmyn – coral snake antivenom * Antivipmyn – pit viper antivenom * Antivipm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polyclonal B Cell Response
Polyclonal B cell response is a natural mode of immune response exhibited by the adaptive immune system of mammals. It ensures that a single antigen is recognized and attacked through its overlapping parts, called epitopes, by multiple clones of B cell. In the course of normal immune response, parts of pathogens (e.g. bacteria) are recognized by the immune system as foreign (non-self), and eliminated or effectively neutralized to reduce their potential damage. Such a recognizable substance is called an antigen. The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function. Antigens can be large and complex substances, and any single antibody can only bind to a small, specific area on the antigen. Conseque ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eastern Coral Snake
''Micrurus fulvius'', commonly known as the eastern coral snake, Behler John L.; King, F. Wayne (1979). ''The Audubon Society Field Guide to North American Reptiles and Amphibians''. New York: Alfred A. Knopf. 743 pp., 657 color plates. LCCCN 79-2217. . (''Micrurus fulvius'', p. 681 + Plates 617, 618). common coral snake, American cobra, Wright, Albert Hazen; Wright, Anna Allen (1957). ''Handbook of Snakes of the United States and Canada''. Ithaca and London: Comstock Publishing Associates. (7th printing, 1985). 1,105 pp. (in 2 volumes). . (''Micrurus fulvius'', pp. 890–897, Map 63, Figures 256–257). and more, is a species of highly venomous coral snake in the family Elapidae. The species is endemic to the southeastern United States. It should not be confused with the scarlet snake (''Cemophora coccinea'') or scarlet kingsnake (''Lampropeltis elapsoides''), which are harmless mimics. No subspecies are currently recognized. Description ''M. fulvius'' is generally less than ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Texas Coral Snake
''Micrurus tener'', commonly known as the Texas coral snake, is a species of venomous snake in the family Elapidae. The species is endemic to the southern United States and northeastern and central Mexico. Five subspecies are recognized as being valid, including the nominotypical subspecies, ''Micrurus tener tener'', which is found in both the US and Mexico, and is also commonly known as the Texas coral snake. The species ''Micrurus tener'' was once considered to be a subspecies of the eastern coral snake (''Micrurus fulvius''). Geographic range ''M. tener'' ranges from the southern United States south to northeastern and central Mexico. It inhabits the states of Texas, Louisiana and Arkansas, and the Mexican states of Tamaulipas, San Luis Potosí, Guanajuato, Querétaro and Morelos. Description The Texas coral snake has the traditional coloration associated with coral snakes: black, yellow, and red rings. It is capable of growing to 48 in (122 cm) in total length (incl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
