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Computer Experiment
A computer experiment or simulation experiment is an experiment used to study a computer simulation, also referred to as an in silico system. This area includes computational physics, computational chemistry, computational biology and other similar disciplines. Background Computer simulations are constructed to emulate a physical system. Because these are meant to replicate some aspect of a system in detail, they often do not yield an analytic solution. Therefore, methods such as discrete event simulation or finite element solvers are used. A computer model is used to make inferences about the system it replicates. For example, climate models are often used because experimentation on an earth sized object is impossible. Objectives Computer experiments have been employed with many purposes in mind. Some of those include: * Uncertainty quantification: Characterize the uncertainty present in a computer simulation arising from unknowns during the computer simulation's construc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Silico
In biology and other experimental sciences, an ''in silico'' experiment is one performed on computer or via computer simulation. The phrase is pseudo-Latin for 'in silicon' (correct la, in silicio), referring to silicon in computer chips. It was coined in 1987 as an allusion to the Latin phrases , , and , which are commonly used in biology (especially systems biology). The latter phrases refer, respectively, to experiments done in living organisms, outside living organisms, and where they are found in nature. History The earliest known use of the phrase was by Christopher Langton to describe artificial life, in the announcement of a workshop on that subject at the Center for Nonlinear Studies at the Los Alamos National Laboratory in 1987. The expression ''in silico'' was first used to characterize biological experiments carried out entirely in a computer in 1989, in the workshop "Cellular Automata: Theory and Applications" in Los Alamos, New Mexico, by Pedro Miramontes, a ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frequentist
Frequentist inference is a type of statistical inference based in frequentist probability, which treats “probability” in equivalent terms to “frequency” and draws conclusions from sample-data by means of emphasizing the frequency or proportion of findings in the data. Frequentist-inference underlies frequentist statistics, in which the well-established methodologies of statistical hypothesis testing and confidence intervals are founded. History of frequentist statistics The history of frequentist statistics is more recent than its prevailing philosophical rival, Bayesian statistics. Frequentist statistics were largely developed in the early 20th century and have recently developed to become the dominant paradigm in inferential statistics, while Bayesian statistics were invented in the 19th century. Despite this dominance, there is no agreement as to whether frequentism is better than Bayesian statistics, with a vocal minority of professionals studying statistical in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Design Of Experiments
The design of experiments (DOE, DOX, or experimental design) is the design of any task that aims to describe and explain the variation of information under conditions that are hypothesized to reflect the variation. The term is generally associated with experiments in which the design introduces conditions that directly affect the variation, but may also refer to the design of quasi-experiments, in which natural conditions that influence the variation are selected for observation. In its simplest form, an experiment aims at predicting the outcome by introducing a change of the preconditions, which is represented by one or more independent variables, also referred to as "input variables" or "predictor variables." The change in one or more independent variables is generally hypothesized to result in a change in one or more dependent variables, also referred to as "output variables" or "response variables." The experimental design may also identify control variables that must be h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gaussian Process Emulator
In statistics, Gaussian process emulator is one name for a general type of statistical model that has been used in contexts where the problem is to make maximum use of the outputs of a complicated (often non-random) computer-based simulation model. Each run of the simulation model is computationally expensive and each run is based on many different controlling inputs. The variation of the outputs of the simulation model is expected to vary reasonably smoothly with the inputs, but in an unknown way. The overall analysis involves two models: the simulation model, or "simulator", and the statistical model, or "emulator", which notionally emulates the unknown outputs from the simulator. The Gaussian process emulator model treats the problem from the viewpoint of Bayesian statistics. In this approach, even though the output of the simulation model is fixed for any given set of inputs, the actual outputs are unknown unless the computer model is run and hence can be made the subject of a B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Simulation
A simulation is the imitation of the operation of a real-world process or system over time. Simulations require the use of Conceptual model, models; the model represents the key characteristics or behaviors of the selected system or process, whereas the simulation represents the evolution of the model over time. Often, computers are used to execute the computer simulation, simulation. Simulation is used in many contexts, such as simulation of technology for performance tuning or optimizing, safety engineering, testing, training, education, and video games. Simulation is also used with scientific modelling of natural systems or human systems to gain insight into their functioning, as in economics. Simulation can be used to show the eventual real effects of alternative conditions and courses of action. Simulation is also used when the real system cannot be engaged, because it may not be accessible, or it may be dangerous or unacceptable to engage, or it is being designed bu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Invertible Matrix
In linear algebra, an -by- square matrix is called invertible (also nonsingular or nondegenerate), if there exists an -by- square matrix such that :\mathbf = \mathbf = \mathbf_n \ where denotes the -by- identity matrix and the multiplication used is ordinary matrix multiplication. If this is the case, then the matrix is uniquely determined by , and is called the (multiplicative) ''inverse'' of , denoted by . Matrix inversion is the process of finding the matrix that satisfies the prior equation for a given invertible matrix . A square matrix that is ''not'' invertible is called singular or degenerate. A square matrix is singular if and only if its determinant is zero. Singular matrices are rare in the sense that if a square matrix's entries are randomly selected from any finite region on the number line or complex plane, the probability that the matrix is singular is 0, that is, it will "almost never" be singular. Non-square matrices (-by- matrices for which ) do not hav ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Low Discrepancy Sequences
In mathematics, a low-discrepancy sequence is a sequence with the property that for all values of ''N'', its subsequence ''x''1, ..., ''x''''N'' has a low discrepancy. Roughly speaking, the discrepancy of a sequence is low if the proportion of points in the sequence falling into an arbitrary set ''B'' is close to proportional to the measure of ''B'', as would happen on average (but not for particular samples) in the case of an equidistributed sequence. Specific definitions of discrepancy differ regarding the choice of ''B'' ( hyperspheres, hypercubes, etc.) and how the discrepancy for every B is computed (usually normalized) and combined (usually by taking the worst value). Low-discrepancy sequences are also called quasirandom sequences, due to their common use as a replacement of uniformly distributed random numbers. The "quasi" modifier is used to denote more clearly that the values of a low-discrepancy sequence are neither random nor pseudorandom, but such sequences share some ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Latin Hypercube Sampling
Latin hypercube sampling (LHS) is a statistical method for generating a near-random sample of parameter values from a multidimensional distribution. The sampling method is often used to construct computer experiments or for Monte Carlo integration. LHS was described by Michael McKay of Los Alamos National Laboratory in 1979. An independently equivalent technique was proposed by Vilnis Eglājs in 1977. It was further elaborated by Ronald L. Iman and coauthors in 1981. Detailed computer codes and manuals were later published. In the context of statistical sampling, a square grid containing sample positions is a Latin square if (and only if) there is only one sample in each row and each column. A Latin hypercube is the generalisation of this concept to an arbitrary number of dimensions, whereby each sample is the only one in each axis-aligned hyperplane containing it. When sampling a function of N variables, the range of each variable is divided into M equally probable interv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Optimal Design
In the design of experiments, optimal designs (or optimum designs) are a class of experimental designs that are optimal with respect to some statistical criterion. The creation of this field of statistics has been credited to Danish statistician Kirstine Smith. In the design of experiments for estimating statistical models, optimal designs allow parameters to be estimated without bias and with minimum variance. A non-optimal design requires a greater number of experimental runs to estimate the parameters with the same precision as an optimal design. In practical terms, optimal experiments can reduce the costs of experimentation. The optimality of a design depends on the statistical model and is assessed with respect to a statistical criterion, which is related to the variance-matrix of the estimator. Specifying an appropriate model and specifying a suitable criterion function both require understanding of statistical theory and practical knowledge with designing exper ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Design Of Experiments
The design of experiments (DOE, DOX, or experimental design) is the design of any task that aims to describe and explain the variation of information under conditions that are hypothesized to reflect the variation. The term is generally associated with experiments in which the design introduces conditions that directly affect the variation, but may also refer to the design of quasi-experiments, in which natural conditions that influence the variation are selected for observation. In its simplest form, an experiment aims at predicting the outcome by introducing a change of the preconditions, which is represented by one or more independent variables, also referred to as "input variables" or "predictor variables." The change in one or more independent variables is generally hypothesized to result in a change in one or more dependent variables, also referred to as "output variables" or "response variables." The experimental design may also identify control variables that must be h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Matern Covariance
Matern is a surname. Notable people with the surname include: *Anik Matern, Canadian actress *Max Matern Max Matern (19 January 1902 – 22 May 1935) was a member of the Communist Party of Germany (KPD) who was convicted of murder and executed for his role in the assassinations of Police Captains Paul Anlauf and Franz Lenck. The murders took plac ... (1902–1935), German communist * Bertil Matérn, (1917 – 2007), Swedish statistician See also * Matern von Marschall {{surname ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Covariance Function
In probability theory and statistics, the covariance function describes how much two random variables change together (their ''covariance'') with varying spatial or temporal separation. For a random field or stochastic process ''Z''(''x'') on a domain ''D'', a covariance function ''C''(''x'', ''y'') gives the covariance of the values of the random field at the two locations ''x'' and ''y'': :C(x,y):=\operatorname(Z(x),Z(y))=\mathbb\left \cdot\ \right\, The same ''C''(''x'', ''y'') is called the autocovariance function in two instances: in time series (to denote exactly the same concept except that ''x'' and ''y'' refer to locations in time rather than in space), and in multivariate random fields (to refer to the covariance of a variable with itself, as opposed to the cross covariance between two different variables at different locations, Cov(''Z''(''x''1), ''Y''(''x''2))). Admissibility For locations ''x''1, ''x''2, …, ''x''''N'' ∈ ''D'' the variance ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
