Coleus Forskohlii
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Coleus Forskohlii
''Coleus barbatus'', also known by the synonyms ''Plectranthus barbatus'' and incorrectly ''Coleus forskalaei'' (and other spellings of this epithet), is a tropical perennial plant related to the typical coleus species. It produces forskolin, an extract useful for pharmaceutical preparations and research in cell biology. Name The Brazilian name is (), or , as opposed to the Chilean true boldo; (); (); or (; 'Oxalá's carpet', because of its velvety texture). Taxonomy ''Coleus barbatus'' was first described by Henry Cranke Andrews in 1810 as ''Plectranthus barbatus''. It was transferred to ''Coleus'' by Bentham in 1830. Although ''Coleus'' was previously sunk into ''Plectranthus'', the original binomial was revived in a major study of the subtribe Plectranthinae in 2019. There has been some confusion over the synonyms of this species. ''Plectranthus forskaolaei'' was first described by Vahl in 1790. Vahl's name is illegitimate, because he treats it as a synonym of the ...
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Henry Cranke Andrews
Henry Cranke Andrews (floruit, fl. 1794 – 1830), was an English botanist, botanical artist and engraver. As he always published as Henry C. Andrews, and due to difficulty finding records, the C. was often referred to as Charles, until a record of his marriage registration was found in 2017. He lived in Knightsbridge, and was married to Anne Kennedy, the daughter of Lee and Kennedy, John Kennedy of Hammersmith, a nurseryman who assisted Andrews in the descriptions of the plants he illustrated. He was an accomplished and unusual botanical artist, in that he was not only the artist but also the engraver, colourist, and publisher of his books in an era when most artists were only employed to draw plates. The ''Botanist's Repository'' was his first publication; issued serially in London in ten volumes between 1797 and 1812, the ''Repository'' at a half-crown an issue, provided affordable images of plants to the growing population of amateur gardeners in Britain. This was the firs ...
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International Plant Names Index
The International Plant Names Index (IPNI) describes itself as "a database of the names and associated basic bibliographical details of seed plants, ferns and lycophytes." Coverage of plant names is best at the rank of species and genus. It includes basic bibliographical details associated with the names. Its goals include eliminating the need for repeated reference to primary sources for basic bibliographic information about plant names. The IPNI also maintains a list of standardized author abbreviations. These were initially based on Brummitt & Powell (1992), but new names and abbreviations are continually added. Description IPNI is the product of a collaboration between The Royal Botanic Gardens, Kew (Index Kewensis), The Harvard University Herbaria (Gray Herbarium Index), and the Australian National Herbarium ( APNI). The IPNI database is a collection of the names registered by the three cooperating institutions and they work towards standardizing the information. The stan ...
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Diterpenoid
Diterpenes are a class of chemical compounds composed of four isoprene units, often with the molecular formula C20H32. They are biosynthesized by plants, animals and fungi via the HMG-CoA reductase pathway, with geranylgeranyl pyrophosphate being a primary intermediate. Diterpenes form the basis for biologically important compounds such as retinol, retinal, and phytol. They are known to be antimicrobial and antiinflammatory. Structures As with most terpenes a huge number of potential structures exists, which may be broadly divided according to the number of rings present. Biosynthesis Diterpenes are derived from the addition of one IPP unit to FPP to form geranylgeranyl-pyrophosphate (GGPP). From GGPP, structural diversity is achieved mainly by two classes of enzymes; the diterpene synthases and cytochromes P450. Several diterpenes are produced by plants and cyanobacteria. GGPP is also the precursor for the synthesis of the phytane by the action of the enzyme geranylger ...
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Glucuronide
A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond. The glucuronides belong to the glycosides. Glucuronidation, the conversion of chemical compounds to glucuronides, is a method that animals use to assist in the excretion of toxic substances, drugs or other substances that cannot be used as an energy source. Glucuronic acid is attached via a glycosidic bond to the substance, and the resulting glucuronide, which has a much higher water solubility than the original substance, is eventually excreted by the kidneys. Enzymes that cleave the glycosidic bond of a glucuronide are called glucuronidases. Examples * Miquelianin (Quercetin 3-O-glucuronide) * Morphine-6-glucuronide * Scutellarein-7-glucuronide Scutellarin is a flavone, a type of phenolic chemical compound. It can be found in the plants '' Scutellaria barbata'' and '' S. lateriflora'' which have been used in traditional medicine''.'' T ...
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Flavonoid
Flavonoids (or bioflavonoids; from the Latin word ''flavus'', meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans. Chemically, flavonoids have the general structure of a 15-carbon skeleton, which consists of two phenyl rings (A and B) and a heterocyclic ring (C, the ring containing the embedded oxygen). This carbon structure can be abbreviated C6-C3-C6. According to the IUPAC nomenclature, they can be classified into: *flavonoids or bioflavonoids *isoflavonoids, derived from 3-phenyl chromen-4-one (3-phenyl-1,4-benzopyrone) structure *neoflavonoids, derived from 4-phenylcoumarine (4-phenyl-1,2-benzopyrone) structure The three flavonoid classes above are all ketone-containing compounds and as such, anthoxanthins ( flavones and flavonols). This class was the first to be termed bioflavonoids. The terms flavonoid and bioflavonoid have also been more loosely used to describe non ...
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Rosmarinic Acid
Rosmarinic acid, named after rosemary (''Salvia rosmarinus'' Linn.), is a polyphenol constituent of many culinary herbs, including rosemary (''Salvia rosmarinus'' L.), perilla (''Perilla frutescens'' L.), Salvia officinalis, sage (''Salvia officinalis'' L.), Lamiaceae, mint (''Mentha arvense'' L.), and basil (''Ocimum basilicum'' L.). History Rosmarinic acid was first isolated and characterized in 1958 by the Italian chemists Scarpatti and Oriente from rosemary (''Salvia rosmarinus''), after which the acid is named. Chemistry Chemically, rosmarinic acid is a caffeic acid ester, with tyrosine providing another phenolic ring via dihydroxyphenyl-lactic acid. It has a molecular mass of 360 dalton (unit), daltons. Natural occurrences Rosmarinic acid accumulation is shown in hornworts, in the fern family Blechnaceae, and in species of several orders of monocotyledon, mono- and dicotyledonous angiosperms. It is found most notably in many Lamiaceae (dicotyledons in the order Lam ...
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Herbal Tea
Herbal teas, also known as herbal infusions and less commonly called tisanes (UK and US , US also ), are beverages made from the infusion or decoction of herbs, spices, or other plant material in hot water. Oftentimes herb tea, or the plain term ''tea'', is used as a reference to all sorts of herbal teas. Many herbs are used in herbal medicine. Some herbal blends contain actual tea (e.g., the Indian classic masala chai). The term "herbal" tea is often used in contrast to the so-called ''true'' teas (e.g., black, green, white, yellow, oolong), which are prepared from the cured leaves of the tea plant, '' Camellia sinensis''. Unlike true teas (which are also available decaffeinated), most tisanes do not naturally contain caffeine. There are a number of plants, however, that ''do'' contain caffeine or another stimulant, like theobromine, cocaine or ephedrine. Some have the opposite effect, acting as a sedative. Some common infusions have specific names such as , ''mate'' (ye ...
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Forskolin
Forskolin (coleonol) is a labdane diterpene produced by the plant ''Coleus barbatus'' (Blue Spur Flower). Other names include pashanabhedi, Indian coleus, makandi, HL-362, mao hou qiao rui hua. As with other members of the large diterpene class of plant metabolites, forskolin is derived from geranylgeranyl pyrophosphate (GGPP). Forskolin contains some unique functional elements, including the presence of a tetrahydropyran-derived heterocyclic ring. Forskolin is commonly used in laboratory research to increase levels of cyclic AMP by stimulation of adenylate cyclase. Mechanism of action Forskolin is commonly used in biochemistry to raise levels of cyclic AMP (cAMP) in the study and research of cell physiology. Forskolin activates the enzyme adenylyl cyclase and increases intracellular levels of cAMP. cAMP is an important second messenger necessary for the proper biological response of cells to hormones and other extracellular signals. It is required for cell communication in the hyp ...
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Coleus Hadiensis
''Coleus'' is a genus of annual or perennial herbs or shrubs, sometimes succulent, sometimes with a fleshy or tuberous rootstock, found in the Old World tropics and subtropics. The relationship among the genera ''Coleus'', ''Solenostemon'' and ''Plectranthus'' has been confused. ''Coleus'' and ''Solenostemon'' were sunk into ''Plectranthus'', but recent phylogenetic analysis found ''Plectranthus'' to be paraphyletic with respect to other related genera in the subtribe Plectranthinae. The most recent taxonomic treatment of the genus resurrected ''Coleus'', and 212 names were changed from combinations in ''Plectranthus'', ''Pycnostachys'' and ''Anisochilus''. ''Equilabium'' was segregated from ''Plectranthus'', after phylogenetic studies supported its recognition as a phylogenetically distinct genus. ''Coleus'' are cultivated as ornamental plants, particularly ''Coleus scutellarioides'' (syns. ''Coleus blumei'', ''Plectranthus scutellarioides''), which is popular as a garden plan ...
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Basionym
In the scientific name of organisms, basionym or basyonym means the original name on which a new name is based; the author citation of the new name should include the authors of the basionym in parentheses. The term "basionym" is used in both botany and zoology. In zoology, alternate terms such as original combination or protonym are sometimes used instead. Bacteriology uses a similar term, basonym, spelled without an ''i''. Although "basionym" and "protonym" are often used interchangeably, they have slightly different technical definitions. A basionym is the ''correct'' spelling of the original name (according to the applicable nomenclature rules), while a protonym is the ''original'' spelling of the original name. These are typically the same, but in rare cases may differ. Use in botany The term "basionym" is used in botany only for the circumstances where a previous name exists with a useful description, and the '' International Code of Nomenclature for algae, fungi, and plants' ...
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International Code Of Nomenclature For Algae, Fungi, And Plants
The ''International Code of Nomenclature for algae, fungi, and plants'' (ICN) is the set of rules and recommendations dealing with the formal botanical names that are given to plants, fungi and a few other groups of organisms, all those "traditionally treated as algae, fungi, or plants".. It was formerly called the ''International Code of Botanical Nomenclature'' (ICBN); the name was changed at the International Botanical Congress in Melbourne in July 2011 as part of the ''Melbourne Code''. which replaced the ''Vienna Code'' of 2005. The current version of the code is the ''Shenzhen Code'' adopted by the International Botanical Congress held in Shenzhen, China, in July 2017. As with previous codes, it took effect as soon as it was ratified by the congress (on 29 July 2017), but the documentation of the code in its final form was not published until 26 June 2018. The name of the ''Code'' is partly capitalized and partly not. The lower-case for "algae, fungi, and plants" indica ...
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Binomial Nomenclature
In taxonomy, binomial nomenclature ("two-term naming system"), also called nomenclature ("two-name naming system") or binary nomenclature, is a formal system of naming species of living things by giving each a name composed of two parts, both of which use Latin grammatical forms, although they can be based on words from other languages. Such a name is called a binomial name (which may be shortened to just "binomial"), a binomen, name or a scientific name; more informally it is also historically called a Latin name. The first part of the name – the '' generic name'' – identifies the genus to which the species belongs, whereas the second part – the specific name or specific epithet – distinguishes the species within the genus. For example, modern humans belong to the genus ''Homo'' and within this genus to the species ''Homo sapiens''. ''Tyrannosaurus rex'' is likely the most widely known binomial. The ''formal'' introduction of this system of naming species is credit ...
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