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Clasp-knife Response
Clasp-knife response refers to a Golgi tendon reflex with a rapid decrease in resistance when attempting to flex a joint, usually during a neurological examination. It is one of the characteristic responses of an upper motor neuron lesion. It gets its name from the resemblance between the motion of the limb and the sudden closing of a claspknife after sufficient pressure is applied. Cause When a joint is passively flexed, the resisting force comes from the stretch reflex (or sometimes called tendon reflex) resulting from the extensor muscle being stretched. In upper motor neuron lesions, muscle tonus may increase and resistance of muscle to stretch increases. However, if sufficient force is applied, limb resistance suddenly decreases, presumably mediated by the Golgi tendon reflex (also call autogenic inhibition). Mechanism This reflex is observed in patients with upper motor neuron lesions. It was frequently attributed to the action of the golgi tendon organ, likely because of e ...
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Golgi Tendon Reflex
The Golgi tendon reflex (also called inverse stretch reflex, autogenic inhibition, tendon reflex) is an inhibitory effect on the muscle resulting from the muscle tension stimulating Golgi tendon organs (GTO) of the muscle, and hence it is self-induced. The reflex arc is a negative feedback mechanism preventing too much tension on the muscle and tendon. When the tension is extreme, the inhibition can be so great it overcomes the excitatory effects on the muscle's alpha motoneurons causing the muscle to suddenly relax. This reflex is also called the inverse myotatic reflex, because it is the inverse of the stretch reflex. GTOs' inhibitory effects come from their reflex arcs: the Ib sensory fibers that are sent through the dorsal root into the spinal cord to synapse on Ib inhibitory interneurons that in turn terminate directly on the motor neurons that innervate the same muscle. The fibers also make direct excitatory synapses onto motoneurons that innervate the antagonist muscle. No ...
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Neurological Examination
A neurological examination is the assessment of sensory neuron and motor responses, especially reflexes, to determine whether the nervous system is impaired. This typically includes a physical examination and a review of the patient's medical history, but not deeper investigation such as neuroimaging. It can be used both as a screening tool and as an investigative tool, the former of which when examining the patient when there is no expected neurological deficit and the latter of which when examining a patient where you do expect to find abnormalities. If a problem is found either in an investigative or screening process, then further tests can be carried out to focus on a particular aspect of the nervous system (such as lumbar punctures and blood tests). In general, a neurological examination is focused on finding out whether there are lesions in the central and peripheral nervous systems or there is another diffuse process that is troubling the patient. Once the patient has been ...
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Upper Motor Neuron Lesion
An upper motor neuron lesion (also known as pyramidal insufficiency) Is an injury or abnormality that occurs in the neural pathway above the anterior horn cell of the spinal cord or motor nuclei of the cranial nerves. Conversely, a lower motor neuron lesion affects nerve fibers traveling from the anterior horn of the spinal cord or the cranial motor nuclei to the relevant muscle(s). Upper motor neuron lesions occur in the brain or the spinal cord as the result of stroke, multiple sclerosis, traumatic brain injury, cerebral palsy, atypical parkinsonisms, multiple system atrophy, and amyotrophic lateral sclerosis. Symptoms Changes in muscle performance can be broadly described as the upper motor neuron syndrome. These changes vary depending on the site and the extent of the lesion, and may include: * Muscle weakness. known as 'pyramidal weakness' * Decreased control of active movement, particularly slowness * Spasticity, a velocity-dependent change in muscle tone * Clasp ...
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Claspknife
A pocketknife is a knife with one or more blades that fold into the handle. They are also known as jackknives (jack-knife), folding knives, or may be referred to as a penknife, though a penknife may also be a specific kind of pocketknife. A typical blade length is . Pocketknives are versatile tools, and may be used for anything from whittling and woodcarving, to butchering small game, gutting and filleting small fish, aiding in the preparation of tinder and kindling for fires, boring holes in soft material, to opening an envelope, cutting twine, slicing a piece of fruit or as a means of self-defense. Specialised designs are also used for mushroom hunting and gardening. Pocketknives designed for gardening include pruning knives, which are folding knives with long curved blades used for pruning, trimming cuttings, taking buds and preparing material for grafting. History The earliest known pocketknives date to at least the early Iron Age. A pocketknife with a bone handle w ...
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Stretch Reflex
The stretch reflex (myotatic reflex), or more accurately "muscle stretch reflex", is a muscle contraction in response to stretching within the muscle. The reflex functions to maintain the muscle at a constant length. The term deep tendon reflex is often used by many health workers and students to refer to this reflex. "Tendons have little to do with the response, other than being responsible for mechanically transmitting the sudden stretch from the reflex hammer to the muscle spindle. In addition, some muscles with stretch reflexes have no tendons (e.g., "jaw jerk" of the masseter muscle)". As an example of a spinal reflex, it results in a fast response that involves an afferent signal into the spinal cord and an efferent signal out to the muscle. The stretch reflex can be a monosynaptic reflex which provides automatic regulation of skeletal muscle length, whereby the signal entering the spinal cord arises from a change in muscle length or velocity. It can also include a polysyna ...
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Muscle Tonus
In physiology, medicine, and anatomy, muscle tone (residual muscle tension or tonus) is the continuous and passive partial contraction of the muscles, or the muscle's resistance to passive stretch during resting state.O’Sullivan, S. B. (2007). Examination of motor function: Motor control and motor learning. In S. B. O’Sullivan, & T. J. Schmitz (Eds), Physical rehabilitation (5th ed.) (pp. 233-234). Philadelphia, Pennsylvania: F. A. Davis Company. It helps to maintain posture and declines during REM sleep. Purpose If a sudden pull or stretch occurs, the body responds by automatically increasing the muscle's tension, a reflex which helps guard against danger as well as helping maintain balance. Such near-continuous innervation can be thought of as a "default" or "steady state" condition for muscles. Both the extensor and flexor muscles are involved in the maintenance of a constant tone while at rest. In skeletal muscles, this helps maintain a normal posture. Resting muscle ...
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Golgi Tendon Organ
The Golgi tendon organ (GTO) (also called Golgi organ, tendon organ, neurotendinous organ or neurotendinous spindle) is a proprioceptor – a type of sensory receptor that senses changes in muscle tension. It lies at the interface between a muscle and its tendon known as the musculotendinous junction also known as the myotendinous junction. It provides the sensory component of the Golgi tendon reflex. The Golgi tendon organ is one of several eponymous terms named after the Italian physician Camillo Golgi. Structure The body of the Golgi tendon organ is made up of braided strands of collagen (intrafusal fasciculi) that are less compact than elsewhere in the tendon and are encapsulated. The capsule is connected in series (along a single path) with a group of muscle fibers () at one end, and merge into the tendon proper at the other. Each capsule is about long, has a diameter of about , and is perforated by one or more afferent type Ib sensory nerve fibers ( Aɑ fiber), whic ...
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Hypertonia
Hypertonia is a term sometimes used synonymously with spasticity and rigidity in the literature surrounding damage to the central nervous system, namely upper motor neuron lesions. Impaired ability of damaged motor neurons to regulate descending pathways gives rise to disordered spinal reflexes, increased excitability of muscle spindles, and decreased synaptic inhibition. These consequences result in abnormally increased muscle tone of symptomatic muscles. Some authors suggest that the current definition for spasticity, the velocity-dependent over-activity of the stretch reflex, is not sufficient as it fails to take into account patients exhibiting increased muscle tone in the absence of stretch reflex over-activity. They instead suggest that "reversible hypertonia" is more appropriate and represents a treatable condition that is responsive to various therapy modalities like drug and/or physical therapy. Presentation Symptoms associated with central nervous systems disorders ar ...
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Somatic Motor System
Somatic may refer to: * Somatic (biology), referring to the cells of the body in contrast to the germ line cells ** Somatic cell, a non-gametic cell in a multicellular organism * Somatic nervous system, the portion of the vertebrate nervous system which regulates voluntary movements of the body * Somatics, a group of alternative medicine approaches, experiential movement disciplines, and dance techniques * Somatic theory, a model of human social behavior Related concepts * Somatic marker hypothesis, an explanation of how emotions affect decision-making * Somatic symptom disorder, aka somatoform disorder, characterized by medically unexplained physical symptoms, and considered to be a mental health issue * Somatotype, the now-discredited idea associating body types with human temperament types * Psychosomatic medicine, an interdisciplinary medical field exploring the relationships among social, psychological, and behavioral factors on bodily processes and quality of life in hum ...
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Neurophysiology
Neurophysiology is a branch of physiology and neuroscience that studies nervous system function rather than nervous system architecture. This area aids in the diagnosis and monitoring of neurological diseases. Historically, it has been dominated by electrophysiology—the electrical recording of neural activity ranging from the molar (the electroencephalogram, EEG) to the cellular (intracellular recording of the properties of single neurons), such as patch clamp, voltage clamp, extracellular single-unit recording and recording of local field potentials. However, since the neurone is an electrochemical machine, it is difficult to isolate electrical events from the metabolic and molecular processes that cause them. Thus, neurophysiologists currently utilise tools from chemistry (calcium imaging), physics (functional magnetic resonance imaging, fMRI), and molecular biology (site directed mutations) to examine brain activity. The word originates from the Greek word meaning "nerve" ...
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