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Chronotype
A chronotype is the behavioral manifestation of underlying circadian rhythm's myriad of physical processes. A person's chronotype is the propensity for the individual to sleep at a particular time during a 24-hour period. ''Eveningness'' (delayed sleep period; most active and alert in the evening) and ''morningness'' (advanced sleep period; most active and alert in the morning) are the two extremes with most individuals having some flexibility in the timing of their sleep period. However, across development there are changes in the propensity of the sleep period with pre-pubescent children preferring an advanced sleep period, adolescents preferring a delayed sleep period and many elderly preferring an advanced sleep period. The causes and regulation of chronotypes, including developmental change, individual propensity for a specific chronotype, and flexible versus fixed chronotypes have yet to be determined. However, research is beginning to shed light on these questions, such as t ...
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Lark (person)
A lark, early bird, morning person, or (in Scandinavian countries) an A-person, is a person who usually gets up early in the morning and goes to bed early in the evening. The term relates to the birds known as larks, which are known to sing before dawn. Human "larks" may sleep from around 10 p.m. to 6 a.m. (or earlier), and tend to feel most energetic just after they get up in the morning. They are thus well-suited for working the day shift. The opposite of the lark is the owl, often awake at night. A person called a ''night owl'' is someone who usually stays up late and may feel most awake in the evening and at night. Researchers have traditionally used the terms morningness and ''eveningness'' to describe these two chronotypes. Charting chronotypes Till Roenneberg, a chronobiologist in Munich, has mapped the circadian rhythms of more than 200,000 people. Biological processes, including sleep-wake patterns, that display an oscillation of about 24 hours are called circadian rhy ...
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Till Roenneberg
Till Roenneberg (born 4 May 1953) is a professor of chronobiology at the Institute of Medical Psychology at Ludwig-Maximilian University (LMU) in Munich, Germany. Roenneberg, in collaboration with Martha Merrow, explores the impact of light on human circadian rhythms, focusing on aspects such as chronotypes and social jet lag in relation to health benefits. Life Roenneberg was born in Munich, Germany. He began working with Jürgen Aschoff at the age of 17. Roenneberg attended both the University College London and Ludwig Maximilian University of Munich where he began by studying physics. He switched to medicine in order to focus on the science of the human body, but ended up studying biology. As a postdoctoral fellow, he studied again under Jürgen Aschoff, studying annual rhythms in the body, then moved to the United States to study the cellular basis of biological clocks under Woody Hastings at Harvard University. In 1991, he began the tradition of giving the Ascho ...
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Night Owl (person)
A night owl, evening person or simply owl, is a person who tends to stay up until late at night, or to the very early hours of the morning. Night owls who are involuntarily unable to fall asleep for several hours after a normal time may have delayed sleep phase disorder. The opposite of a night owl is an early bird – a lark as opposed to an owl – which is someone who tends to begin sleeping at a time that is considered early and also wakes early. Researchers traditionally use the terms ''morningness'' and eveningness for the two chronotypes or diurnality and nocturnality in animal behavior. In several countries, especially in Scandinavia, early birds are called ''A-people'' and a night owl is called a B-person. History While staying up after dark was considered a negative trait, this changed in 17th and 18th century Europe (and subsequently spread beyond) due to the development and implementation of artificial lighting: more domestic lights, added street lighting, and adap ...
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Morningness–eveningness Questionnaire
The morningness–eveningness questionnaire (MEQ) is a self-assessment questionnaire developed by researchers James A. Horne and Olov Östberg in 1976. Its main purpose is to measure whether a person's circadian rhythm (biological clock) produces peak alertness in the morning, in the evening, or in between. The original study showed that the subjective time of peak alertness correlates with the time of peak body temperature; morning types ( early birds) have an earlier temperature peak than evening types ( night owls), with intermediate types having temperature peaks between the morning and evening chronotype groups. The MEQ is widely used in psychological and medical research and has been professionally cited more than 4,000 times. MEQ questions The standard MEQ consists of 19 multiple-choice questions, each having four or five response options. Some example questions are: Responses to the questions are combined to form a composite score that indicates the degree to which the ...
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Sleep
Sleep is a sedentary state of mind and body. It is characterized by altered consciousness, relatively inhibited sensory activity, reduced muscle activity and reduced interactions with surroundings. It is distinguished from wakefulness by a decreased ability to react to stimuli, but more reactive than a coma or disorders of consciousness, with sleep displaying different, active brain patterns. Sleep occurs in repeating periods, in which the body alternates between two distinct modes: REM sleep and non-REM sleep. Although REM stands for "rapid eye movement", this mode of sleep has many other aspects, including virtual paralysis of the body. Dreams are a succession of images, ideas, emotions, and sensations that usually occur involuntarily in the mind during certain stages of sleep. During sleep, most of the body's systems are in an anabolic state, helping to restore the immune, nervous, skeletal, and muscular systems; these are vital processes that maintain mood, memory, an ...
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Circadian Rhythm Sleep Disorder
Circadian rhythm sleep disorders (CRSD), also known as circadian rhythm sleep-wake disorders (CRSWD), are a family of sleep disorders which affect the timing of sleep. CRSDs arise from a persistent pattern of sleep/wake disturbances that can be caused either by dysfunction in one's biological clock system, or by misalignment between one's endogenous oscillator and externally imposed cues. As a result of this mismatch, those affected by circadian rhythm sleep disorders have a tendency to fall asleep at unconventional time points in the day. These occurrences often lead to recurring instances of disturbed rest, where individuals affected by the disorder are unable to go to sleep and awaken at "normal" times for work, school, and other social obligations. Delayed sleep phase disorder, advanced sleep phase disorder, non-24-hour sleep–wake disorder and irregular sleep–wake rhythm disorder represents the four main types of CRSD. Overview Humans, like most living organisms, hav ...
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Chronobiology
Chronobiology is a field of biology that examines timing processes, including periodic (cyclic) phenomena in living organisms, such as their adaptation to solar- and lunar-related rhythms. These cycles are known as biological rhythms. Chronobiology comes from the ancient Greek χρόνος (''chrónos'', meaning "time"), and biology, which pertains to the study, or science, of life. The related terms ''chronomics'' and ''chronome'' have been used in some cases to describe either the molecular mechanisms involved in chronobiological phenomena or the more quantitative aspects of chronobiology, particularly where comparison of cycles between organisms is required. Chronobiological studies include but are not limited to comparative anatomy, physiology, genetics, molecular biology and behavior of organisms related to their biological rhythms. Other aspects include epigenetics, development, reproduction, ecology and evolution. The subject Chronobiology studies variations of the ...
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Circadian Rhythm
A circadian rhythm (), or circadian cycle, is a natural, internal process that regulates the sleep–wake cycle and repeats roughly every 24 hours. It can refer to any process that originates within an organism (i.e., endogenous) and responds to the environment ( entrained by the environment). These 24-hour rhythms are driven by a circadian clock, and they have been widely observed in animals, plants, fungi and cyanobacteria. The term ''circadian'' comes from the Latin ''circa'', meaning "approximately", and ''dies'', meaning "day". Processes with 24-hour cycles are more generally called diurnal rhythms; diurnal rhythms should not be called circadian rhythms unless they can be confirmed as endogenous, and not environmental. Although circadian rhythms are endogenous, they are adjusted to the local environment by external cues called zeitgebers (German for "time givers"), which include light, temperature and redox cycles. In clinical settings, an abnormal circadian rhythm in h ...
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Zeitgeber
A zeitgeber () is any external or environmental cue that entrains or synchronizes an organism's biological rhythms, usually naturally occurring and serving to entrain to the Earth's 24-hour light/dark and 12-month cycles. History The term ' (; ) was first used by Jürgen Aschoff, one of the founders of the field of chronobiology. His work demonstrated the existence of endogenous (internal) biological clocks, which synchronize biological rhythms. In addition, he found that certain exogenous (external) cues, which he called zeitgeber, influence the timing of these internal clocks. Photic and nonphotic zeitgebers * Light (light is a more important zeitgeber than social interactions). * Atmospheric conditions * Medication * Temperature * Social interactions * Exercise * Eating/drinking patterns Circadian rhythms Any biological process in the body that repeats itself over a period of approximately 24 hours and maintains this rhythm in the absence of external stimuli is considered a ci ...
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Drosophila Melanogaster
''Drosophila melanogaster'' is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the " vinegar fly" or "pomace fly". Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, ''D. melanogaster'' continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. As of 2017, five Nobel Prizes have been awarded to drosophilists for their work using the insect. ''D. melanogaster'' is typically used in research owing to its rapid life cycle, relatively simple genetics with only four pairs of chromosomes, and large number of offspring per generation. It was originally an African species, with all non-African lineages having a common origin. Its geographic range includes all continents, including islands. ''D. melanogaster'' is a common pest in homes, restaurants, and ...
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University Of South Carolina Salkehatchie
The University of South Carolina Salkehatchie (USC Salkehatchie) is a public college with campuses in Allendale and Walterboro, South Carolina. It is one of four regional University of South Carolina System campuses which make up Palmetto College. USC Salkehatchie is accredited by the Southern Association of Colleges and Schools as part of the flagship campus ( University of South Carolina Columbia). More than 1100 students attend at one of its two sites. History The citizens of Allendale, Bamberg, and Hampton counties led an effort in 1964 to establish a center of higher education for their region of South Carolina. The proposal was warmly received by the General Assembly, and the Western Carolina Higher Education Commission was created to investigate the possibility of a college for the region. House Speaker Solomon Blatt pleaded with the University of South Carolina to build two-year colleges across the state so as to prevent any possible expansion by Clemson. As a r ...
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PER2
PER2 is a protein in mammals encoded by the ''PER2'' gene. ''PER2'' is noted for its major role in circadian rhythms. Discovery The ''per ''gene'' ''was first discovered using forward genetics in '' Drosophilla melanogaster'' in 1971. Mammalian Per2 was discovered by in 1997 through a search for homologous cDNA sequences to PER1. It is more similar to Drosophila '' per'' than its paralogs. Later experiments in also identified ''Per2 ''in humans. Function ''PER2'' is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian clock, which regulates the daily rhythms of locomotor activity, metabolism, and behavior. Circadian expression of these genes and their encoded proteins in the suprachiasmatic nucleus. Human PER2 is involved in human sleep disorder and cancer formation. Lowered ''PER2'' expression is common in ...
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