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Chlorophenoxy Herbicide
Chlorophenoxy herbicides are a subclass of phenoxy herbicides which includes: MCPA, 2,4-D, 2,4,5-T and mecoprop. Large amounts have been produced since the 1950s for agriculture. Acute toxic effects after oral consumption are varied and may include: vomiting, abdominal pain, diarrhoea, gastrointestinal haemorrhage acutely followed by coma, hypertonia, hyperreflexia, ataxia, nystagmus, miosis, hallucinations and convulsions. Treatment with urinary alkalinization may be helpful but evidence to support this practice is limited. See also *Health effects of pesticides Health effects of pesticides may be acute or delayed in those who are exposed. Acute effects can include pesticide poisoning, which may be a medical emergency. Strong evidence exists for other, long-term negative health outcomes from pesticide exp ... References {{herbicides Herbicides ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phenoxy Herbicide
Phenoxy herbicides (or "phenoxies") are two families of chemicals that have been developed as commercially important herbicides, widely used in agriculture. They share the part structure of phenoxyacetic acid. Auxins The first group to be discovered act by mimicking the growth hormone indoleacetic acid (IAA). When sprayed on broad-leaf plants they induce rapid, uncontrolled growth ("growing to death"). Thus when applied to monocotyledonous crops such as wheat or corn, they selectively kill broad-leaf weeds, leaving the crops relatively unaffected. File:Indol-3-ylacetic acid.svg, IAA File:2-(4-chloro-2-methylphenoxy)acetic acid 200.svg, MCPA File:2,4-Dichlorophenoxyacetic acid structure.svg, 2,4-D File:2,4,5-T.svg, 2,4,5-T Introduced in 1946, these herbicides were in widespread use in agriculture by the middle of the 1950s. The best known phenoxy herbicides are (4-chloro-2-methylphenoxy)acetic acid (MCPA), 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic ac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypertonia
Hypertonia is a term sometimes used synonymously with spasticity and rigidity in the literature surrounding damage to the central nervous system, namely upper motor neuron lesions. Impaired ability of damaged motor neurons to regulate descending pathways gives rise to disordered spinal reflexes, increased excitability of muscle spindles, and decreased synaptic inhibition. These consequences result in abnormally increased muscle tone of symptomatic muscles. Some authors suggest that the current definition for spasticity, the velocity-dependent over-activity of the stretch reflex, is not sufficient as it fails to take into account patients exhibiting increased muscle tone in the absence of stretch reflex over-activity. They instead suggest that "reversible hypertonia" is more appropriate and represents a treatable condition that is responsive to various therapy modalities like drug and/or physical therapy. Presentation Symptoms associated with central nervous systems disorders ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Urinary Alkalinization
Sodium bicarbonate (IUPAC name: sodium hydrogencarbonate), commonly known as baking soda or bicarbonate of soda, is a chemical compound with the formula NaHCO3. It is a salt composed of a sodium cation ( Na+) and a bicarbonate anion ( HCO3−). Sodium bicarbonate is a white solid that is crystalline, but often appears as a fine powder. It has a slightly salty, alkaline taste resembling that of washing soda (sodium carbonate). The natural mineral form is nahcolite. It is a component of the mineral natron and is found dissolved in many mineral springs. Nomenclature Because it has long been known and widely used, the salt has many different names such as baking soda, bread soda, cooking soda, and bicarbonate of soda and can often be found near baking powder in stores. The term ''baking soda'' is more common in the United States, while ''bicarbonate of soda'' is more common in Australia, United Kingdom and Ireland. and in many northern/central European countries it is called ''Na ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Convulsions
A convulsion is a medical condition where the body muscles contract and relax rapidly and repeatedly, resulting in uncontrolled shaking. Because epileptic seizures typically include convulsions, the term ''convulsion'' is sometimes used as a synonym for ''seizure''. However, not all epileptic seizures lead to convulsions, and not all convulsions are caused by epileptic seizures. Convulsions are also consistent with an electric shock and improper enriched air scuba diving. Non-epileptic convulsions have no relation with epilepsy, and are caused by non-epileptic seizures. Convulsion is a common term generally describing uncontrollable muscle contractions. The term convulsion has been used interchangeably with the word "seizure". Seizures may cause a person to have convulsions, but this is not always the case. Convulsion is a type of seizure that involves bursts of electrical activity in the brain. Occasionally the reason for a convulsion is unfamiliar. A convulsion may be caused ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Miosis
Miosis, or myosis (), is excessive constriction of the pupil. citing: Mosby's Medical Dictionary, 8th ed. The opposite condition, , is the dilation of the pupil. Anisocoria is the condition of one being more dilated than the other. Causes Age * Senile miosis (a reduction in the size of a person's pupil in old age)Diseases * ...[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nystagmus
Nystagmus is a condition of involuntary (or voluntary, in some cases) eye movement. Infants can be born with it but more commonly acquire it in infancy or later in life. In many cases it may result in reduced or limited vision. Due to the involuntary movement of the eye, it has been called "dancing eyes". In normal eyesight, while the head rotates about an axis, distant visual images are sustained by rotating eyes in the opposite direction of the respective axis. The semicircular canals in the vestibule of the ear sense angular acceleration, and send signals to the nuclei for eye movement in the brain. From here, a signal is relayed to the extraocular muscles to allow one's gaze to fix on an object as the head moves. Nystagmus occurs when the semicircular canals are stimulated (e.g., by means of the caloric test, or by disease) while the head is stationary. The direction of ocular movement is related to the semicircular canal that is being stimulated. There are two key form ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ataxia
Ataxia is a neurological sign consisting of lack of voluntary coordination of muscle movements that can include gait abnormality, speech changes, and abnormalities in eye movements. Ataxia is a clinical manifestation indicating dysfunction of the parts of the nervous system that coordinate movement, such as the cerebellum. Ataxia can be limited to one side of the body, which is referred to as hemiataxia. Several possible causes exist for these patterns of neurological dysfunction. Dystaxia is a mild degree of ataxia. Friedreich's ataxia has gait abnormality as the most commonly presented symptom. The word is from Greek α- negative prefix+ -τάξις rder= "lack of order". Types Cerebellar The term cerebellar ataxia is used to indicate ataxia due to dysfunction of the cerebellum. The cerebellum is responsible for integrating a significant amount of neural information that is used to coordinate smoothly ongoing movements and to participate in motor planning. Although a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hyperreflexia
Hyperreflexia is overactive or overresponsive bodily reflexes. Examples of this include twitching and spastic tendencies, which indicate upper disease of the upper motor neurons and the lessening or loss of control ordinarily exerted by higher brain centers of lower neural pathways (disinhibition). The most common cause of hyperreflexia is spinal-cord injury (''see'' " Autonomic dysreflexia"). Standard stimuli, such as the filling of the bladder, can cause excessive responses from the nervous system; the causes are not known. Hyperreflexia also has many other causes, including the side effects of drugs and stimulants; hyperthyroidism; electrolyte imbalance; serotonin syndrome; severe brain trauma; multiple sclerosis; Reye syndrome; and preeclampsia. Treatment depends on the cause of the hyperreflexia. If drugs cause it, treatment may require that they not be used. Recovery from hyperreflexia can occur several hours to several months after a spinal-cord injury; the phase o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coma
A coma is a deep state of prolonged unconsciousness in which a person cannot be awakened, fails to respond normally to painful stimuli, light, or sound, lacks a normal wake-sleep cycle and does not initiate voluntary actions. Coma patients exhibit a complete absence of wakefulness and are unable to consciously feel, speak or move. Comas can be derived by natural causes, or can be medically induced. Clinically, a coma can be defined as the inability consistently to follow a one-step command. It can also be defined as a score of ≤ 8 on the Glasgow Coma Scale (GCS) lasting ≥ 6 hours. For a patient to maintain consciousness, the components of ''wakefulness'' and ''awareness'' must be maintained. Wakefulness describes the quantitative degree of consciousness, whereas awareness relates to the qualitative aspects of the functions mediated by the cortex, including cognitive abilities such as attention, sensory perception, explicit memory, language, the execution of tasks, temporal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MCPA
MCPA (2-methyl-4-chlorophenoxyacetic acid) is a powerful, selective, widely used phenoxy herbicide. The pure compound is a brown-colored powder. MCPA has been extensively used in agriculture to control broad-leaf weeds as a growth regulator primarily in pasture and cereal crops field since 1945. The mode of action of MCPA is as an auxin, which are growth hormones that naturally exist in plants. Overdose application of MCPA acts as an herbicide and results in abnormal growth. History In 1936 investigations began at ICIs Jealott's Hill research center into the effects of auxins on plant growth looking specifically for a way to kill weeds without harming crops such as wheat and oats. William Templeman found that when indole-3-acetic acid (IAA), the naturally occurring auxin, was used at high concentrations, it could stop plant growth. In 1940, he published his finding that IAA killed broadleaf plants within a cereal field. Templeman and the ICI group were searching for compounds w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gastrointestinal Haemorrhage
Gastrointestinal bleeding (GI bleed), also called gastrointestinal hemorrhage (GIB), is all forms of bleeding in the gastrointestinal tract, from the mouth to the rectum. When there is significant blood loss over a short time, symptoms may include vomiting red blood, vomiting black blood, bloody stool, or black stool. Small amounts of bleeding over a long time may cause iron-deficiency anemia resulting in feeling tired or heart-related chest pain. Other symptoms may include abdominal pain, shortness of breath, pale skin, or passing out. Sometimes in those with small amounts of bleeding no symptoms may be present. Bleeding is typically divided into two main types: upper gastrointestinal bleeding and lower gastrointestinal bleeding. Causes of upper GI bleeds include: peptic ulcer disease, esophageal varices due to liver cirrhosis and cancer, among others. Causes of lower GI bleeds include: hemorrhoids, cancer, and inflammatory bowel disease among others. Diagnosis typically ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diarrhoea
Diarrhea, also spelled diarrhoea, is the condition of having at least three loose, liquid, or watery bowel movements each day. It often lasts for a few days and can result in dehydration due to fluid loss. Signs of dehydration often begin with loss of the normal stretchiness of the skin and irritable behaviour. This can progress to decreased urination, loss of skin color, a fast heart rate, and a decrease in responsiveness as it becomes more severe. Loose but non-watery stools in babies who are exclusively breastfed, however, are normal. The most common cause is an infection of the intestines due to either a virus, bacterium, or parasite—a condition also known as gastroenteritis. These infections are often acquired from food or water that has been contaminated by feces, or directly from another person who is infected. The three types of diarrhea are: short duration watery diarrhea, short duration bloody diarrhea, and persistent diarrhea (lasting more than two weeks, whic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
