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Charles Vacanti
Charles Alfred "Chuck" Vacanti (born 1950) is a researcher in tissue engineering and stem cells and the Vandam/Covino Professor of Anesthesiology, Emeritus, at Harvard Medical School. He is a former head of the Department of Anesthesiology at the University of Massachusetts and Brigham and Women’s Hospital, now retired. He is known for the Vacanti mouse, a mouse created with Linda Griffith and Joseph Upton with cartilage shaped like a human ear on its back, and for being the senior author on the first of two retracted articles on STAP cells, a concept proposed by his brother and himself, and co-authored with Haruko Obokata. Career Vacanti graduated from Creighton Preparatory High School, gained his B.A. from Creighton University in 1968, and his M.D. from University of Nebraska College of Medicine in 1975, and then completed his surgical intern and residency at Medical Center Hospital of Vermont (now called the University of Vermont Medical Center) in 1978. With his b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Omaha, Nebraska
Omaha ( ) is the largest city in the U.S. state of Nebraska and the county seat of Douglas County. Omaha is in the Midwestern United States on the Missouri River, about north of the mouth of the Platte River. The nation's 39th-largest city, Omaha's 2020 census population was 486,051. Omaha is the anchor of the eight-county, bi-state Omaha-Council Bluffs metropolitan area. The Omaha Metropolitan Area is the 58th-largest in the United States, with a population of 967,604. The Omaha-Council Bluffs-Fremont, NE-IA Combined Statistical Area (CSA) totaled 1,004,771, according to 2020 estimates. Approximately 1.5 million people reside within the Greater Omaha area, within a radius of Downtown Omaha. It is ranked as a global city by the Globalization and World Cities Research Network, which in 2020 gave it "sufficiency" status. Omaha's pioneer period began in 1854, when the city was founded by speculators from neighboring Council Bluffs, Iowa. The city was founded along th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Retractions In Academic Publishing
In academic publishing, a retraction is the action by which a published paper in an academic journal is removed from the journal. Procedure A retraction may be initiated by the editors of a journal, or by the author(s) of the papers (or their institution). Retractions are typically accompanied by a retraction notice written by the editors or authors explaining the reason for the retraction. Such notices may also include a note from the authors with apologies for the previous error and/or expressions of gratitude to persons who disclosed the error to the author. A lesser withdrawal of content than a full retraction may be labelled a correction. There have been numerous examples of retracted scientific publications. Retraction Watch provides updates on new retractions, and discusses general issues in relation to retractions. History A 2011 paper in the ''Journal of Medical Ethics'' attempted to quantify retraction rates in PubMed over time to determine if the rate was incr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Teratoma
A teratoma is a tumor made up of several different types of tissue, such as hair, muscle, teeth, or bone. Teratomata typically form in the ovary, testicle, or coccyx. Symptoms Symptoms may be minimal if the tumor is small. A testicular teratoma may present as a painless lump. Complications may include ovarian torsion, testicular torsion, or hydrops fetalis. They are a type of germ cell tumor (a tumor that begins in the cells that give rise to sperm or eggs). They are divided into two types: mature and immature. Mature teratomas include dermoid cysts and are generally benign. Immature teratomas may be cancerous. Most ovarian teratomas are mature. In adults, testicular teratomas are generally cancerous. Definitive diagnosis is based on a tissue biopsy. Treatment of coccyx, testicular, and ovarian teratomas is generally by surgery. Testicular and immature ovarian teratomas are also frequently treated with chemotherapy. Teratomas occur in the coccyx in about one in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Koji Kojima (researcher) , a fungus used in East Asian fermentation
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Koji, Kōji, Kohji or Kouji may refer to: *Kōji (given name), a masculine Japanese given name *Kōji (Heian period) (康治), Japanese era, 1142–1144 *Kōji (Muromachi period) (弘治), Japanese era, 1555–1558 *Koji orange, a Japanese citrus cultivar *Andrew Koji Shiraki (born 1987), singer/songwriter known as ''Koji'' *Koji, the software that builds RPM packages for the Fedora project *''Koji'', the common name of the fungus ''Aspergillus oryzae'' *Koji, an interactive content creation tool from GoMeta See also *Kojii, music project by Kojii Helnwein *''Coji-Coji'' (コジコジ), an anime series sometimes romanized ''Koji Koji'' *Kōji mold Aspergillus oryzae ''Aspergillus oryzae'', also known as , is a filamentous fungus (a mold) used in East Asia to saccharify rice, sweet potato, and barley in the making of alcoholic beverages such as '' sake'' and ''shōchū'', and also to ferment soybeans f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spore-like Cells
Spore-like cells were proposed to be pluripotent cells that lie dormant in animal tissue and become active under stress or injury as adult stem cells, exhibiting behavior characteristic of spores. They were proposed in 2001 by brothers Charles and Martin Vacanti and colleagues. Further work in collaboration with Japanese researchers led to the apparent discovery of STAP cells, in which the pluripotent cells were newly created by stress or injury. This work was published in 2014, but soon found to be due to fraudulent work by Haruko Obokata. Characteristics Spore-like cells were said to be a specific class of stem cells in adult organisms, including humans, which are small, versatile, and most frequently remain in a dormant "spore-like" state as the rest of the cells of the organism divide, grow, and die. Despite their dormancy, they apparently retain the ability to grow, divide, and differentiate into other cell types expressing characteristics appropriate to the tissue environm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pluripotent
Pluripotency: These are the cells that can generate into any of the three Germ layers which imply Endodermal, Mesodermal, and Ectodermal cells except tissues like the placenta. According to Latin terms, Pluripotentia means the ability for many things. We can generate Induced Pluripotent cells by using the Induced pluripotency technique by triggering or expressing the genes or the transcription factors of the normal somatic cells. They are abbreviated as iPSC or IPS. We can forcefully express the transcription factors like Oct4, Sox2, Klf4, and c- Myc of a non-pluripotent cell and convert them into a stem cell. This procedure is first studied in a Mouse fibroblast cell in 2006 and followed the same instructions in developing a Human pluripotent cell from a Human epidermal fibroblast cell. The technique is called Regeneration. Though the iPSC has similar properties to embryonic stem cells they were never approved for clinical stage research because they are highly Tumerogenic, h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nude Mouse
A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells. The phenotype (main outward appearance) of the mouse is a lack of body hair, which gives it the "nude" nickname. The nude mouse is valuable to research because it can receive many different types of tissue and tumor grafts, as it mounts no rejection response. These xenografts are commonly used in research to test new methods of imaging and treating tumors. The genetic basis of the nude mouse mutation is a disruption of the FOXN1 gene. Nomenclature The nomenclature for the nude mouse has changed several times since their discovery. Originally they were described as ''nu'' and this was updated to ''Hfh11nu'' when the mutated gene was identified as a mutation in the HNF-3/forkhead homolog 11 gene. Then in 2000 the gene responsible for the mutation was identified as a member of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Langer
Robert Samuel Langer Jr. FREng (born August 29, 1948) is an American chemical engineer, scientist, entrepreneur, inventor and one of the twelve Institute Professors at the Massachusetts Institute of Technology. He was formerly the Germeshausen Professor of Chemical and Biomedical Engineering and maintains activity in the Department of Chemical Engineering and the Department of Biological Engineering at MIT. He is also a faculty member of the Harvard–MIT Program in Health Sciences and Technology and the Koch Institute for Integrative Cancer Research. Langer holds over 1,400 granted or pending patents. He is one of the world's most highly cited researchers and his h-index is now 305 with currently over 376,000 citations. He is a widely recognized and cited researcher in biotechnology, especially in the fields of drug delivery systems and tissue engineering. He is the most cited engineer in history and 2nd most cited individual in any field, having authored over 1,500 scie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tissue Engineering Society
Tissue may refer to: Biology * Tissue (biology), an ensemble of similar (or dissimilar in structure but same in origin) cells that together carry out a specific function * ''Triphosa haesitata'', a species of geometer moth ("tissue moth") found in North America * ''Triphosa dubitata'', a species of geometer moth ("tissue") found in Afro-Eurasia Paper products * Tissue paper, a type of thin, gauzy translucent paper used for wrapping and cushioning items ** Facial tissue, tissue paper used for cleaning the face ** Japanese tissue, tissue paper from Japan made of vegetable fibers ** Toilet paper, tissue paper used for cleaning the anus ** Wrapping tissue, tissue paper used for wrapping and cushioning items Other * Aerial tissue Aerial silks (also known as aerial contortion, aerial ribbons, aerial tissues, fabric, ribbon, or ''tissu'') is a type of performance in which one or more artists perform aerial acrobatics while hanging from a specialist fabric. The fabric may b ..., an ac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Simon Gelman
Simon may refer to: People * Simon (given name), including a list of people and fictional characters with the given name Simon * Simon (surname), including a list of people with the surname Simon * Eugène Simon, French naturalist and the genus authority ''Simon'' * Tribe of Simeon, one of the twelve tribes of Israel Places * Şimon ( hu, links=no, Simon), a village in Bran Commune, Braşov County, Romania * Șimon, a right tributary of the river Turcu in Romania Arts, entertainment, and media Films * ''Simon'' (1980 film), starring Alan Arkin * ''Simon'' (2004 film), Dutch drama directed by Eddy Terstall Games * ''Simon'' (game), a popular computer game * Simon Says, children's game Literature * ''Simon'' (Sutcliff novel), a children's historical novel written by Rosemary Sutcliff * Simon (Sand novel), an 1835 novel by George Sand * ''Simon Necronomicon'' (1977), a purported grimoire written by an unknown author, with an introduction by a man identified only as "Simo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alpha Omega Alpha
Alpha Omega Alpha Honor Medical Society () is an honor society in the field of medicine. Alpha Omega Alpha currently has active Chapters in 132 LCME- accredited medical schools in the United States and Lebanon. It annually elects over 4,000 new members. The majority of new members are elected in their final year of medical school, but distinguished teachers, faculty members, residents, and alumni can also be inducted into the society. All elections are held at local Chapters. No elections are held nationally. History ΑΩΑ was founded in 1902 by William Webster Root and five other medical students at the College of Physicians and Surgeons, which later became the University of Illinois College of Medicine. The impetus for its formation was the generally poor quality of American medical schools and students at the time; Root and his colleagues wished to promote excellence in these groups. They decided that membership in ΑΩΑ was to be based on both scholarly achievement and pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Vermont Medical Center
The University of Vermont Medical Center (UVMMC) is a five-campus academic medical facility under the corporate umbrella of the University of Vermont Health Network that is anchored by a 562-bed hospital. UVMMC is located in Burlington, Vermont, and serves as both a regional referral center (providing advanced care to approximately one million people in Vermont and northern New York) and a community hospital (for approximately 160,000 residents in the Chittenden and Grand Isle Vermont counties). The hospital was formerly known as the ''Medical Center Hospital of Vermont'' and later as ''Fletcher Allen Health Care'' until getting its current name. It is affiliated with the University of Vermont's Robert Larner College of Medicine and the College of Nursing and Health Sciences. Overview The University of Vermont Medical Center ("UVM Medical Center") consists of five major campuses: *Medical Center Campus, Burlington, a 562 licensed-bed facility that includes most inpatient s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
