Charles Knight (cardiologist)
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Charles Knight (cardiologist)
Charles Knight MD FRCP OBE is a British professor of cardiology and chief executive of St Bartholomew's Hospital, part of Barts Health NHS Trust. In 1994 he assisted in the first percutaneous alcohol septal ablation, a non-surgical method for the treatment of hypertrophic obstructive cardiomyopathy as an alternative to open heart surgery, and subsequently specialised in the procedure. From 2010 he led the development of the Barts Heart Centre at Barts Health NHS Trust which opened in 2015 by merging cardiac services from the London Chest Hospital, The Heart Hospital and St Bartholomew's Hospital. In 2020, Knight was appointed chief executive officer of NHS Nightingale Hospital London, established to care for people during the COVID-19 pandemic. In the same year he was awarded an OBE for services to the NHS and people with heart disease. He is on the list of honorary medical staff at the private King Edward VII's Hospital. Education Charles Knight trained at Cambridge ...
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Alcohol Septal Ablation
Alcohol septal ablation (ASA) is a minimally invasive heart procedure to treat hypertrophic cardiomyopathy (HCM). It is a percutaneous, minimally invasive procedure performed by an interventional cardiologist to relieve symptoms and improve functional status in eligible patients with severely symptomatic HCM who meet strict clinical, anatomic and physiologic selection criteria. In carefully selected patients, when performed by an experienced interventional cardiologist, the procedure is successful in relieving symptoms in over 90% of patients. Hypertrophic cardiomyopathy is a condition of the cardiac muscle which grows abnormally thick in the absence of a pathophysiologic cause such as hypertension (high blood pressure) or aortic valve disease. In a large subset of patients with hypertrophic obstructive cardiomyopathy, thickening of the heart muscle in a particular part of the interventricular septum causes obstruction to blood being ejected from the left ventricle. Alcohol ...
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COVID-19 Lockdown In The United Kingdom
The COVID-19 lockdown in the United Kingdom was a series of stay-at-home orders introduced by the British and devolved governments in response to the COVID-19 pandemic. On 23 March 2020, Prime Minister Boris Johnson announced a nationwide lockdown to curb a widening outbreak of COVID-19, closing many sectors and ordering the public to stay at home. This was incrementally lifted, starting from several weeks later. Similar restrictions were introduced in late 2020 and early 2021 as infections rose. Restrictions applied to certain areas, and then on a larger scale, differing between the four countries of the United Kingdom to which Health is devolved, with the central government being responsible for England. First nationwide lockdown The initial announcement was made by Boris Johnson, with agreement from the other three heads of government. At 8:30 p.m. on 23 March 2020, Boris Johnson announced a stay-at-home order effective immediately, though only legally effective from 1 ...
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Elizabeth II
Elizabeth II (Elizabeth Alexandra Mary; 21 April 1926 – 8 September 2022) was Queen of the United Kingdom and other Commonwealth realms from 6 February 1952 until her death in 2022. She was queen regnant of 32 sovereign states during her lifetime, and was head of state of 15 realms at the time of her death. Her reign of 70 years and 214 days was the longest of any British monarch and the longest verified reign of any female monarch in history. Elizabeth was born in Mayfair, London, as the first child of the Duke and Duchess of York (later King George VI and Queen Elizabeth The Queen Mother). Her father acceded to the throne in 1936 upon the abdication of his brother Edward VIII, making the ten-year-old Princess Elizabeth the heir presumptive. She was educated privately at home and began to undertake public duties during the Second World War, serving in the Auxiliary Territorial Service. In November 1947, she married Philip Mountbatten, a former prince ...
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Prince Philip, Duke Of Edinburgh
Prince Philip, Duke of Edinburgh (born Prince Philip of Greece and Denmark, later Philip Mountbatten; 10 June 1921 – 9 April 2021) was the husband of Queen Elizabeth II. As such, he served as the consort of the British monarch from Elizabeth's accession as queen on 6 February 1952 until his death in 2021, making him the longest-serving royal consort in history. Philip was born in Greece, into the Greek and Danish royal families; his family was exiled from the country when he was eighteen months old. After being educated in France, Germany, and the United Kingdom, he joined the Royal Navy in 1939, when he was 18 years old. In July 1939, he began corresponding with the 13-year-old Princess Elizabeth, the elder daughter and heir presumptive of King George VI. Philip had first met her in 1934. During the Second World War, he served with distinction in the British Mediterranean and Pacific fleets. In the summer of 1946, the King granted Philip permission to marry El ...
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COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was COVID-19 pandemic in Hubei, identified in Wuhan, China, in December 2019. The disease quickly spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 are variable but often include fever, cough, headache, fatigue, breathing difficulties, Anosmia, loss of smell, and Ageusia, loss of taste. Symptoms may begin one to fourteen days incubation period, after exposure to the virus. At least a third of people who are infected Asymptomatic, do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, Hypoxia (medical), hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure ...
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Royal Society Of Medicine
The Royal Society of Medicine (RSM) is a medical society in the United Kingdom, headquartered in London. History The Society was established in 1805 as Medical and Chirurgical Society of London, meeting in two rooms in barristers’ chambers at Gray's Inn and then moving to Lincoln's Inn Fields where it stayed for 25 years. In 1834 the Society moved to Berners Street and was granted a Royal Charter by King William IV. In 1889 under the leadership of Sir John MacAlister, a Building Committee chaired by Timothy Holmes supervised the move of the quarters of the Society from Berners Street to 20 Hanover Square. In 1905 an eleven-member committee headed by Sir Richard Douglas Powell organised the celebration of the Society's centenary. Two years later the Royal Medical and Chirurgical Society of London came together with seventeen specialist medical societies and, with a supplementary Royal Charter granted by Edward VII, became the Royal Society of Medicine. In 1910 the Society ...
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Ulrich Sigwart
Ulrich Sigwart (; born 9 March 1941) is a German retired cardiologist known for his pioneering role in the conception and clinical use of stents to keep blood vessels open, and introducing a non-surgical intervention, alcohol septal ablation for the treatment of hypertrophic obstructive cardiomyopathy. Sigwart received his medical degree in 1967 from the University of Münster before gaining his MD that same year from the University of Freiburg. In 1984, he performed the first coronary stent and 10 years later introduced percutaneous alcohol septal ablation, a non-surgical method for the treatment of hypertrophic obstructive cardiomyopathy, as an alternative to open heart surgery. Early life and education Ulrich Sigwart was born on 9 March 1941 in Wuppertal, Germany, the fifth child of August R. Sigwart, a Bayer Industries scientist, and his wife Elizabeth. He was an infant when his father died under suspicious circumstances in Nazi-occupied Europe. His family has its origin ...
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List Of Honorary Medical Staff At King Edward VII's Hospital For Officers
The King Edward VII's Hospital for Officers (KEVII) was established first as Sister Agnes' hospital in 1899 by Sister Agnes, and was then formally opened as King Edward VII's Hospital for Officers in 1904 by King Edward VII, who selected and appointed the first honorary medical staff. In 1914, Sister Agnes compiled a list of 23 honorary physicians and surgeons just a few days before the First World War. Although open to all London consultants, at that time, the status of the medical staff on the list was considered such that patients rarely requested the service from any other London physician or surgeon. The list was abandoned in 1919 and reinstated when the new hospital opened in Beaumont Street in 1948. Closely associated with the Royal Family, the hospital was noted around the time of its centenary, to have in its list of physicians and surgeons around 100 staff, which required the inclusion of the Royal Medical Household. In 2018 there were 300 physicians and surgeons at t ...
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Cardiovascular Disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, abnormal heart rhythms, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease, thromboembolic disease, and venous thrombosis. The underlying mechanisms vary depending on the disease. It is estimated that dietary risk factors are associated with 53% of CVD deaths. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes mellitus, lack of exercise, obesity, high blood cholesterol, poor diet, excessive alcohol consumption, and poor sleep, among other things. High blood pressure is estimated to account for approximat ...
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National Health Service
The National Health Service (NHS) is the umbrella term for the publicly funded healthcare systems of the United Kingdom (UK). Since 1948, they have been funded out of general taxation. There are three systems which are referred to using the "NHS" name ( NHS England, NHS Scotland and NHS Wales). Health and Social Care in Northern Ireland was created separately and is often locally referred to as "the NHS". The four systems were established in 1948 as part of major social reforms following the Second World War. The founding principles were that services should be comprehensive, universal and free at the point of delivery—a health service based on clinical need, not ability to pay. Each service provides a comprehensive range of health services, free at the point of use for people ordinarily resident in the United Kingdom apart from dental treatment and optical care. In England, NHS patients have to pay prescription charges; some, such as those aged over 60 and certain state ben ...
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COVID-19 Pandemic In The United Kingdom
The COVID-19 pandemic in the United Kingdom is a part of the worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In the United Kingdom, it has resulted in confirmed cases, and is associated with deaths. The virus began circulating in the country in early 2020, arriving primarily from travel elsewhere in Europe. Various sectors responded, with more widespread public health measures incrementally introduced from March 2020. The first wave was at the time one of the world's largest outbreaks. By mid-April the peak had been passed and restrictions were gradually eased. A second wave, with a new variant that originated in the UK becoming dominant, began in the autumn and peaked in mid-January 2021, and was deadlier than the first. The UK started a COVID-19 vaccination programme in early December 2020. Generalised restrictions were gradually lifted and were mostly ended by August 2021. A third wave, ...
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