Charles Blackley
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Charles Blackley
Charles Harrison Blackley (5 April 1820 – 4 September 1900) was the discoverer of the mechanism behind allergic rhinitis caused by pollen, commonly called hay fever. The isolation of hay fever as a condition had been known since 1819 through the work of John Bostock. Blackley was the first to connect pollen to the condition, and though he held some later discredited views, his insight was an important step in the research of allergens. His most important work was a book titled the ''Experimental Researches on the Causes and Nature of Catarrhus aestivus'', published in 1873. Charles Darwin had read this book and wrote to thank him for it. He was very interested in Blackley’s experiments and in another letter explained that some pollens are wind-blown while others depend on insects for dispersal, for which Blackley was extremely grateful. Correspondence between Blackley and Darwin is being published through the Darwin Correspondence Project The British naturalist Charles ...
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Bolton
Bolton (, locally ) is a large town in Greater Manchester in North West England, formerly a part of Lancashire. A former mill town, Bolton has been a production centre for textiles since Flemish people, Flemish weavers settled in the area in the 14th century, introducing a wool and cotton-weaving tradition. The urbanisation and development of the town largely coincided with the introduction of textile manufacture during the Industrial Revolution. Bolton was a 19th-century boomtown and, at its zenith in 1929, its 216 cotton mills and 26 bleaching and dyeing works made it one of the largest and most productive centres of Spinning (textiles), cotton spinning in the world. The British cotton industry declined sharply after the First World War and, by the 1980s, cotton manufacture had virtually ceased in Bolton. Close to the West Pennine Moors, Bolton is north-west of Manchester and lies between Manchester, Darwen, Blackburn, Chorley, Bury, Greater Manchester, Bury and ...
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Lancashire
Lancashire ( , ; abbreviated Lancs) is the name of a historic county, ceremonial county, and non-metropolitan county in North West England. The boundaries of these three areas differ significantly. The non-metropolitan county of Lancashire was created by the Local Government Act 1972. It is administered by Lancashire County Council, based in Preston, and twelve district councils. Although Lancaster is still considered the county town, Preston is the administrative centre of the non-metropolitan county. The ceremonial county has the same boundaries except that it also includes Blackpool and Blackburn with Darwen, which are unitary authorities. The historic county of Lancashire is larger and includes the cities of Manchester and Liverpool as well as the Furness and Cartmel peninsulas, but excludes Bowland area of the West Riding of Yorkshire transferred to the non-metropolitan county in 1974 History Before the county During Roman times the area was part of the Bri ...
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Ormskirk
Ormskirk is a market town in the West Lancashire district of Lancashire, England, north of Liverpool, northwest of St Helens, southeast of Southport and southwest of Preston. Ormskirk is known for its gingerbread. Geography and administration Ormskirk lies on sloping ground on the side of a ridge, whose highest point is above sea-level, at the centre of the West Lancashire Plain, and has been described as a "planned borough", laid out in the 13th century.Lancashire County Council
Ormskirk historic town assessment, Lancashire County Council, 2006
Ormskirk is an , surrounded by the

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Allergic Rhinitis
Allergic rhinitis, of which the seasonal type is called hay fever, is a type of inflammation in the nose that occurs when the immune system overreacts to allergens in the air. Signs and symptoms include a runny or stuffy nose, sneezing, red, itchy, and watery eyes, and swelling around the eyes. The fluid from the nose is usually clear. Symptom onset is often within minutes following allergen exposure, and can affect sleep and the ability to work or study. Some people may develop symptoms only during specific times of the year, often as a result of pollen exposure. Many people with allergic rhinitis also have asthma, allergic conjunctivitis, or atopic dermatitis. Allergic rhinitis is typically triggered by environmental allergens such as pollen, pet hair, dust, or mold. Inherited genetics and environmental exposures contribute to the development of allergies. Growing up on a farm and having multiple siblings decreases this risk. The underlying mechanism involves IgE antibodies ...
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Pollen
Pollen is a powdery substance produced by seed plants. It consists of pollen grains (highly reduced microgametophytes), which produce male gametes (sperm cells). Pollen grains have a hard coat made of sporopollenin that protects the gametophytes during the process of their movement from the stamens to the pistil of flowering plants, or from the male cone to the female cone of gymnosperms. If pollen lands on a compatible pistil or female cone, it germinates, producing a pollen tube that transfers the sperm to the ovule containing the female gametophyte. Individual pollen grains are small enough to require magnification to see detail. The study of pollen is called palynology and is highly useful in paleoecology, paleontology, archaeology, and forensics. Pollen in plants is used for transferring haploid male genetic material from the anther of a single flower to the stigma of another in cross-pollination. In a case of self-pollination, this process takes place from the anth ...
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John Bostock (physician)
John Bostock, Jr. FRS (baptised 29 June 1773, died 6 August 1846) was an English physician, scientist and geologist from Liverpool. Life Bostock was a son of Dr. John Bostock, Sr. He spent some time at New College at Hackney where he attended Joseph Priestley's lectures on chemistry and natural philosophy, before graduating in Medicine at the University of Edinburgh and practising medicine in Liverpool. He moved to London in 1817 where he concentrated on general science. In 1819, Bostock was first to accurately describe hay fever as a disease that affected the upper respiratory tract. He lectured on chemistry at Guy's Hospital and was President of the Geological Society of London in 1826 when that body was granted a Royal Charter and Vice President of the Royal Society in 1832. Bostock died of cholera in 1846; He is buried in the Kensal Green Cemetery, London. Works Bostock was one of the first chemical pathologists. He was the first to realise the relationship between the di ...
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Correspondence Of Charles Darwin
The British naturalist Charles Darwin corresponded with his extended family and with an extraordinarily wide range of people from all over the world. The letters, over 15,000 in all, provide many insights on issues ranging from the origins of key scientific concepts, to religious and philosophical discussions which have continued to the present day. The letters also illuminate many aspects of Darwin and his biography: the development of his ideas; insights into character and health; and private opinions on controversial issues. His letters to the Harvard botanist Asa Gray, for example, show his opinions on slavery and the American Civil War. Darwin relied upon correspondence for much of his scientific work, and also used letters to marshal support for his ideas amongst friends and colleagues. The historian of science Janet Browne has argued that Darwin's ability to correspond daily played a crucial role in the development of his theory and his ability to garner support for it fr ...
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1820 Births
Eighteen or 18 may refer to: * 18 (number), the natural number following 17 and preceding 19 * one of the years 18 BC, AD 18, 1918, 2018 Film, television and entertainment * ''18'' (film), a 1993 Taiwanese experimental film based on the short story ''God's Dice'' * ''Eighteen'' (film), a 2005 Canadian dramatic feature film * 18 (British Board of Film Classification), a film rating in the United Kingdom, also used in Ireland by the Irish Film Classification Office * 18 (''Dragon Ball''), a character in the ''Dragon Ball'' franchise * "Eighteen", a 2006 episode of the animated television series ''12 oz. Mouse'' Music Albums * ''18'' (Moby album), 2002 * ''18'' (Nana Kitade album), 2005 * '' 18...'', 2009 debut album by G.E.M. Songs * "18" (5 Seconds of Summer song), from their 2014 eponymous debut album * "18" (One Direction song), from their 2014 studio album ''Four'' * "18", by Anarbor from their 2013 studio album '' Burnout'' * "I'm Eighteen", by Alice Cooper commo ...
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1900 Deaths
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipk ...
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People From Bolton
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ...
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