Catharanthus
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Catharanthus
''Catharanthus'' is a genus of flowering plants in the family Apocynaceae. Like the genus ''Vinca'', they are known commonly as periwinkles. There are eight known species. Seven are endemic to Madagascar,''Catharanthus''.
Madagascar Catalogue. eFloras.
though one, ''C. roseus'', is widely naturalized around the world. The eighth species, ''C. pusillus'', is native to and . The name ''Catharanthus'' comes from the for "pure flower".
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Catharanthus Roseus
''Catharanthus roseus'', commonly known as bright eyes, Cape periwinkle, graveyard plant, Madagascar periwinkle, old maid, pink periwinkle, rose periwinkle, is a species of flowering plant in the family Apocynaceae. It is native and endemic to Madagascar, but grown elsewhere as an ornamental and medicinal plant. It is a source of the drugs vincristine and vinblastine, used to treat cancer. It was formerly included in the genus ''Vinca'' as ''Vinca rosea''. It has many vernacular names among which are ''arivotaombelona'' or ''rivotambelona'', ''tonga'', ''tongatse'' or ''trongatse'', ''tsimatiririnina'', and ''vonenina''. Synonyms Two varieties are recognized * ''Catharanthus roseus'' var. ''roseus'' : Synonymy for this variety ::''Catharanthus roseus'' var. ''angustus'' Steenis ex Bakhuizen f. :: ''Catharanthus roseus'' var. ''albus'' G.DonG.Don, Gen. Hist. 4(1): 95. 1837. :: ''Catharanthus roseus'' var. ''occellatus'' G.Don :: ''Catharanthus roseus'' var. ''nanus'' Markgr. :: ...
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Catharanthus
''Catharanthus'' is a genus of flowering plants in the family Apocynaceae. Like the genus ''Vinca'', they are known commonly as periwinkles. There are eight known species. Seven are endemic to Madagascar,''Catharanthus''.
Madagascar Catalogue. eFloras.
though one, ''C. roseus'', is widely naturalized around the world. The eighth species, ''C. pusillus'', is native to and . The name ''Catharanthus'' comes from the for "pure flower".
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Vincristine
Vincristine, also known as leurocristine and marketed under the brand name Oncovin among others, is a chemotherapy medication used to treat a number of types of cancer. This includes acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer among others. It is given intravenously. Most people experience some side effects from vincristine treatment. Commonly it causes a change in sensation, hair loss, constipation, difficulty walking, and headaches. Serious side effects may include neuropathic pain, lung damage, or low white blood cells which increases the risk of infection. Use during pregnancy may result in birth defects. It works by stopping cells from dividing properly. It is vital that it not be given intrathecally, as this causes paralysis and in most cases, death. Vincristine was first isolated in 1961. It is on the World Health Organization's List of Essential Medicines. It is a vinca alkaloid that can be obtained ...
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Catharanthus Trichophyllus
''Catharanthus trichophyllus'' is a species of flowering plant in the family Apocynaceae. It is endemic to Madagascar, where it is most common in northern regions.Schmelzer, G. H. (2007)''Catharanthus trichophyllus'' (Baker) Pichon. In: Schmelzer, G. H. and A. Gurib-Fakim. (Editors). Prota 11(1): Medicinal Plants/''Plantes Médicinales'' 1. PROTA. Wageningen, Netherlands. Description This is a perennial herb growing up to one meter tall. It has an unpleasant scent. It contains a white latex. The stems and branches are squared, winged, and reddish or purplish in color. The oppositely arranged leaves have hairy, pointed oval blades up to 8.5 centimeters long. They are each accompanied by several stipules. Flowers occur singly or in pairs in the leaf axils. The calyx is up to a centimeter long and has five long, narrow lobes. The corolla has a tubular throat over 2 centimeters long opening into five lobes each up to 1.8 centimeters long. The flowers may be white, pink, red, or purpl ...
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Apocynaceae
Apocynaceae (from ''Apocynum'', Greek for "dog-away") is a family of flowering plants that includes trees, shrubs, herbs, stem succulents, and vines, commonly known as the dogbane family, because some taxa were used as dog poison Members of the family are native to the European, Asian, African, Australian, and American tropics or subtropics, with some temperate members. The former family Asclepiadaceae (now known as Asclepiadoideae) is considered a subfamily of Apocynaceae and contains 348 genera. A list of Apocynaceae genera may be found here. Many species are tall trees found in tropical forests, but some grow in tropical dry (xeric) environments. Also perennial herbs from temperate zones occur. Many of these plants have milky latex, and many species are poisonous if ingested, the family being rich in genera containing alkaloids and cardiac glycosides, those containing the latter often finding use as arrow poisons. Some genera of Apocynaceae, such as '' Adenium'', bleed clea ...
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Catharanthus Ovalis
''Catharanthus ovalis'' is a species of flowering plant in the dogbane family, Apocynaceae. It is endemic to Madagascar. First published as a species in 1970, several subspecies or varieties have been proposed, however none are now recognized. Tropicos.org. Missouri Botanical Garden. 09 Jun 2019


References

ovalis Ovalis, oval in Latin, may refer to: * Fossa ovalis (other) * Limbus of fossa ovalis The ''fossa ovalis'' is a depression in the right atrium of the heart, at the level of the interatrial septum, the wall between right and left atri ...
Endemic flora of Madagascar {{Apocynaceae-stub ...
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Vinca
''Vinca'' (; Latin: ''vincire'' "to bind, fetter") is a genus of flowering plants in the family Apocynaceae, native to Europe, northwest Africa and southwest Asia. The English name periwinkle is shared with the related genus ''Catharanthus'' (and also with the common seashore mollusc, ''Littorina littorea''). Description ''Vinca'' plants are subshrubs or herbaceous, and have slender trailing stems long but not growing more than above ground; the stems frequently take root where they touch the ground, enabling the plant to spread widely. The leaves are opposite, simple broad lanceolate to ovate, long and broad; they are evergreen in four species, but deciduous in the herbaceous '' V. herbacea'', which dies back to the root system in winter.Blamey, M., & Grey-Wilson, C. (1989). ''Flora of Britain and Northern Europe''. Hodder & Stoughton.Huxley, A., ed. (1992). ''New RHS Dictionary of Gardening'' 4: 664-665. Macmillan. The flowers, produced through most of the growing season, ...
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Catharanthus Scitulus
''Catharanthus scitulus'' is a species of flowering plant in the family Apocynaceae. It is endemic to Madagascar Madagascar (; mg, Madagasikara, ), officially the Republic of Madagascar ( mg, Repoblikan'i Madagasikara, links=no, ; french: République de Madagascar), is an island country in the Indian Ocean, approximately off the coast of East Africa .... References scitulus Endemic flora of Madagascar {{Apocynaceae-stub ...
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Catharanthus Pusillus
''Catharanthus pusillus'', commonly known as the tiny periwinkle, is a species of flowering plant in the family Apocynaceae. It is native to India and Sri Lanka. References pusillus {{Short pages monitor [Baidu]  


Catharanthus Longifolius
''Catharanthus longifolius'' is a species of flowering plant in the dogbane family, Apocynaceae. It is endemic to Madagascar Madagascar (; mg, Madagasikara, ), officially the Republic of Madagascar ( mg, Repoblikan'i Madagasikara, links=no, ; french: République de Madagascar), is an island country in the Indian Ocean, approximately off the coast of East Africa .... References longifolius Endemic flora of Madagascar {{Apocynaceae-stub ...
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Vinca Alkaloid
''Vinca'' alkaloids are a set of anti-mitotic and anti-microtubule alkaloid agents originally derived from the periwinkle plant ''Catharanthus roseus'' (basionym ''Vinca rosea'') and other ''vinca'' plants. They block beta-tubulin polymerization in a dividing cell. Sources The Madagascan periwinkle ''Catharanthus roseus'' L. is the source for a number of important natural products, including catharanthine and vindoline and the vinca alkaloids it produces from them: leurosine and the chemotherapy agents vinblastine and vincristine, all of which can be obtained from the plant. The newer semi-synthetic chemotherapeutic agent vinorelbine is used in the treatment of non-small-cell lung cancer and is not known to occur naturally. However, it can be prepared either from vindoline and catharanthine or from leurosine, in both cases by synthesis of anhydrovinblastine, which "can be considered as the key intermediate for the synthesis of vinorelbine." The leurosine pathway uses the Nug ...
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Vinblastine
Vinblastine (VBL), sold under the brand name Velban among others, is a chemotherapy medication, typically used with other medications, to treat a number of types of cancer. This includes Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, melanoma, and testicular cancer. It is given by injection into a vein. Most people experience some side effects. Commonly it causes a change in sensation, constipation, weakness, loss of appetite, and headaches. Severe side effects include low blood cell counts and shortness of breath. It should not be given to people who have a current bacterial infection. Use during pregnancy will likely harm the baby. Vinblastine works by blocking cell division. Vinblastine was isolated in 1958. An example of a natural herbal remedy that has since been developed into a conventional medicine, vinblastine was originally obtained from the Madagascar periwinkle. It is on the World Health Organization's List of Essential Medicines. ...
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