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CD85
The term "CD85" was originally used to refer to LILR1 which is now known as LILRB1, CD85j; however, there are a number of CD85 genes: {{cite book , last = Carrington , first = M , authorlink = , author2=Norman, P , title = The KIR Gene Cluster (e-book) , publisher = NCBI Bookshelf , year = 2003 , location = , pages = , url = https://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=mono_003∂=A1 , doi = , id = , isbn = ''LILR: leukocyte immunoglobulin-like receptor; ILT: immunoglobulin-like transcript; LIR: leukocyte inhibitory receptor; MIR: macrophage inhibitory receptor.'' References [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
LILR1
Leukocyte immunoglobulin-like receptor subfamily B member 1 is a protein that in humans is encoded by the ''LILRB1'' gene. Function This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. See also * Cluster of differentiation References Further r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |