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Curculigoside
Curculigosides are phenols that have been isolated from a variety of plant sources. Curculigoside A, B, C and D can be found in ''Curculigo orchioides''. Curculigoside B can be isolated by high-speed counter-current chromatography. Curculigosides B and D have ''in vitro'' activity against β-amyloid Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which is ... aggregation. References {{reflist Phenol glycosides Curculigo Phenol ethers ...
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Curculigoside B
Curculigosides are phenols that have been isolated from a variety of plant sources. Curculigoside A, B, C and D can be found in ''Curculigo orchioides''. Curculigoside B can be isolated by high-speed counter-current chromatography. Curculigosides B and D have ''in vitro'' activity against β-amyloid Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which is ... aggregation. References {{reflist Phenol glycosides Curculigo Phenol ethers ...
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Curculigoside C
Curculigosides are phenols that have been isolated from a variety of plant sources. Curculigoside A, B, C and D can be found in ''Curculigo orchioides''. Curculigoside B can be isolated by high-speed counter-current chromatography. Curculigosides B and D have ''in vitro'' activity against β-amyloid Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which is ... aggregation. References {{reflist Phenol glycosides Curculigo Phenol ethers ...
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Curculigoside D
Curculigosides are phenols that have been isolated from a variety of plant sources. Curculigoside A, B, C and D can be found in ''Curculigo orchioides''. Curculigoside B can be isolated by high-speed counter-current chromatography. Curculigosides B and D have ''in vitro'' activity against β-amyloid Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which is ... aggregation. References {{reflist Phenol glycosides Curculigo Phenol ethers ...
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Curculigoside B
Curculigosides are phenols that have been isolated from a variety of plant sources. Curculigoside A, B, C and D can be found in ''Curculigo orchioides''. Curculigoside B can be isolated by high-speed counter-current chromatography. Curculigosides B and D have ''in vitro'' activity against β-amyloid Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which is ... aggregation. References {{reflist Phenol glycosides Curculigo Phenol ethers ...
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Curculigo Orchioides
''Curculigo orchioides'' (commonly called golden eye-grass, xian mao, weevil-wort, कालो मुस्ली (in Nepal) black musli, Kali musli, or Kali Musali) is an endangered flowering plant species in the genus ''Curculigo''. It is native to Nepal, China, Japan, the Indian subcontinent, Papuasia, and Micronesia. Names ''C. orchidoides'' is known as ''Nilappana'' (നിലപ്പന) meaning ground palm in Malayalam, କୁଆକେନ୍ଦା in Odiya, ତାଳମୂଳୀ in Bengali-Tallur, and நிலப்பனை in Tamil Tamil may refer to: * Tamils, an ethnic group native to India and some other parts of Asia ** Sri Lankan Tamils, Tamil people native to Sri Lanka also called ilankai tamils **Tamil Malaysians, Tamil people native to Malaysia * Tamil language, nati .... Chemical compounds From ''C. orchidoides'', several chemical compounds of the curculigoside class including curculigoside A, B, C and D and curculigine A and D have been isolated. ...
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Curculigoside A
Curculigoside A is a curculigoside found in ''Curculigo orchioides ''Curculigo orchioides'' (commonly called golden eye-grass, xian mao, weevil-wort, कालो मुस्ली (in Nepal) black musli, Kali musli, or Kali Musali) is an endangered flowering plant species in the genus ''Curculigo''. It is nati ...''.Two new benzylbenzoate glucosides from Curculigo orchioides. Josep Valls, Tristan Richard, Fabienne Larronde, Véronique Leblais, Bernard Muller, Jean-Claude Delaunay, Jean-Pierre Monti, K.G. Ramawat and Jean-Michel Mérillon, Fitoterapia, Volume 77, Issue 6, September 2006, Pages 416-419, References Phenol glucosides Curculigo Phenol ethers Carboxylate esters {{aromatic-stub ...
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Phenol
Phenol (also called carbolic acid) is an aromatic organic compound with the molecular formula . It is a white crystalline solid that is volatile. The molecule consists of a phenyl group () bonded to a hydroxy group (). Mildly acidic, it requires careful handling because it can cause chemical burns. Phenol was first extracted from coal tar, but today is produced on a large scale (about 7 billion kg/year) from petroleum-derived feedstocks. It is an important industrial commodity as a precursor to many materials and useful compounds. It is primarily used to synthesize plastics and related materials. Phenol and its chemical derivatives are essential for production of polycarbonates, epoxies, Bakelite, nylon, detergents, herbicides such as phenoxy herbicides, and numerous pharmaceutical drugs. Properties Phenol is an organic compound appreciably soluble in water, with about 84.2 g dissolving in 1000 mL (0.895 M). Homogeneous mixtures of phenol and water at phenol ...
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High-speed Counter-current Chromatography
Countercurrent chromatography (CCC, also counter-current chromatography) is a form of liquid–liquid chromatography that uses a liquid stationary phase that is held in place by inertia of the molecules composing the stationary phase accelerating toward the center of a centrifuge due to centripetal force and is used to separate, identify, and quantify the chemical components of a mixture. In its broadest sense, countercurrent chromatography encompasses a collection of related liquid chromatography techniques that employ two immiscible liquid phases without a solid support. The two liquid phases come in contact with each other as at least one phase is pumped through a column, a hollow tube or a series of chambers connected with channels, which contains both phases. The resulting dynamic mixing and settling action allows the components to be separated by their respective solubilities in the two phases. A wide variety of two-phase solvent systems consisting of at least two immiscible l ...
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In Vitro
''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, and whole plants. Definition ''In vitro'' ( la, in glass; often not italicized in English usage) studies are conducted using components of an organism that have been isolated fro ...
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β-amyloid
Amyloid beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. The peptides derive from the amyloid precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ in a cholesterol-dependent process and substrate presentation. Aβ molecules can aggregate to form flexible soluble oligomers which may exist in several forms. It is now believed that certain misfolded oligomers (known as "seeds") can induce other Aβ molecules to also take the misfolded oligomeric form, leading to a chain reaction akin to a prion infection. The oligomers are toxic to nerve cells. The other protein implicated in Alzheimer's disease, tau protein, also forms such prion-like misfolded oligomers, and there is some evidence that misfolded Aβ can induce tau to misfold. A study has suggested that APP and its amyloid potential is of ancient origins, dating as far back a ...
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Phenol Glycosides
Phenol (also called carbolic acid) is an aromatic organic compound with the molecular formula . It is a white crystalline solid that is volatile. The molecule consists of a phenyl group () bonded to a hydroxy group (). Mildly acidic, it requires careful handling because it can cause chemical burns. Phenol was first extracted from coal tar, but today is produced on a large scale (about 7 billion kg/year) from petroleum-derived feedstocks. It is an important industrial commodity as a precursor to many materials and useful compounds. It is primarily used to synthesize plastics and related materials. Phenol and its chemical derivatives are essential for production of polycarbonates, epoxies, Bakelite, nylon, detergents, herbicides such as phenoxy herbicides, and numerous pharmaceutical drugs. Properties Phenol is an organic compound appreciably soluble in water, with about 84.2 g dissolving in 1000 mL (0.895 M). Homogeneous mixtures of phenol and water at phenol to wate ...
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Curculigo
''Curculigo'' is a flowering plant genus in the family Hypoxidaceae, first described in 1788. It is widespread across tropical regions of Asia, Africa, Australia, and the Americas. Curculin is a sweet protein that was discovered and isolated in 1990 from the fruit of ''Curculigo latifolia'', a plant from Malaysia. Like miraculin, curculin exhibits taste-modifying activity; however, unlike miraculin, it also exhibits a sweet taste by itself. After consumption of curculin, water and sour solutions taste sweet. The plant is referred to locally as 'lembah' or 'lumbah'; English: 'weevil-wort'. ;Species # '' Curculigo annamitica'' Gagnep. – Vietnam # '' Curculigo breviscapa'' S.C.Chen – China (Guangxi, Guangdong) # '' Curculigo conoc'' Gagnep. – Vietnam # '' Curculigo disticha'' Gagnep. – Vietnam # '' Curculigo ensifolia'' R.Br. – Australia # '' Curculigo erecta'' Lauterb. – Philippines, Sumatra, New Guinea, Solomon Island # '' Curculigo maharashtrensis'' M.R.Almeida & ...
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