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Cunninghamella Bertholletiae
''Cunninghamella bertholletiae'' is a species of zygomycetous fungi in the order '' Mucorales''. It is found globally, with increased prevalence in Mediterranean and subtropical climates. It typically grows as a saprotroph and is found in a wide variety of substrates, including soil, fruits, vegetables, nuts, crops, and human and animal waste. Although infections are still rare, ''C. betholletiae'' is emerging as an opportunistic human pathogen, predominantly in immunocompromised people, leukemia patients, and people with uncontrolled diabetes. ''Cunninghamella bertholletiae'' infections are often highly invasive, and can be more difficult to treat with antifungal drugs than infections with other species of the ''Mucorales'', making prompt and accurate recognition and diagnosis of mycoses Fungal infection, also known as mycosis, is disease caused by fungi. Different types are traditionally divided according to the part of the body affected; superficial, subcutaneous, and ...
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Fungi
A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from the other eukaryotic kingdoms, which by one traditional classification include Plantae, Animalia, Protozoa, and Chromista. A characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. Fungi, like animals, are heterotrophs; they acquire their food by absorbing dissolved molecules, typically by secreting digestive enzymes into their environment. Fungi do not photosynthesize. Growth is their means of mobility, except for spores (a few of which are flagellated), which may travel through the air or water. Fungi are the principal decomposers in ecological systems. These and other differences place fungi in a single group of related organisms, named the ''Eumycota'' (''t ...
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Ascomycota
Ascomycota is a phylum of the kingdom Fungi that, together with the Basidiomycota, forms the subkingdom Dikarya. Its members are commonly known as the sac fungi or ascomycetes. It is the largest phylum of Fungi, with over 64,000 species. The defining feature of this fungal group is the " ascus" (), a microscopic sexual structure in which nonmotile spores, called ascospores, are formed. However, some species of the Ascomycota are asexual, meaning that they do not have a sexual cycle and thus do not form asci or ascospores. Familiar examples of sac fungi include morels, truffles, brewers' and bakers' yeast, dead man's fingers, and cup fungi. The fungal symbionts in the majority of lichens (loosely termed "ascolichens") such as ''Cladonia'' belong to the Ascomycota. Ascomycota is a monophyletic group (it contains all descendants of one common ancestor). Previously placed in the Deuteromycota along with asexual species from other fungal taxa, asexual (or anamorphic) ascomyce ...
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Zygospore
A zygospore is a diploid reproductive stage in the life cycle of many fungi and protists. Zygospores are created by the nuclear fusion of haploid cells. In fungi, zygospores are formed in zygosporangia after the fusion of specialized budding structures, from mycelia of the same (in homothallic fungi) or different mating types (in heterothallic fungi), and may be chlamydospores. In many eukaryotic algae, including many species of the Chlorophyta, zygospores are formed by the fusion of unicellular gametes of different mating types. A zygospore remains dormant while it waits for environmental cues, such as light, moisture, heat, or chemicals secreted by plants. When the environment is favorable, the zygospore germinates, meiosis occurs, and haploid vegetative cells are released. In fungi, a sporangium is produced at the end of a sporangiophore that sheds spores. A fungus that forms zygospores is called a zygomycete, indicating that the class Class or The Class may refer to: Com ...
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Sexual Reproduction
Sexual reproduction is a type of reproduction that involves a complex life cycle in which a gamete ( haploid reproductive cells, such as a sperm or egg cell) with a single set of chromosomes combines with another gamete to produce a zygote that develops into an organism composed of cells with two sets of chromosomes ( diploid). This is typical in animals, though the number of chromosome sets and how that number changes in sexual reproduction varies, especially among plants, fungi, and other eukaryotes. Sexual reproduction is the most common life cycle in multicellular eukaryotes, such as animals, fungi and plants. Sexual reproduction also occurs in some unicellular eukaryotes. Sexual reproduction does not occur in prokaryotes, unicellular organisms without cell nuclei, such bacteria and archaea. However, some process in bacteria may be considered analogous to sexual reproduction in that they incorporate new genetic information, including bacterial conjugation, transformatio ...
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Cycloheximide
Cycloheximide is a naturally occurring fungicide produced by the bacterium ''Streptomyces griseus''. Cycloheximide exerts its effects by interfering with the translocation step in protein synthesis (movement of two tRNA molecules and mRNA in relation to the ribosome), thus blocking eukaryotic translational elongation. Cycloheximide is widely used in biomedical research to inhibit protein synthesis in eukaryotic cells studied ''in vitro'' (''i.e.'' outside of organisms). It is inexpensive and works rapidly. Its effects are rapidly reversed by simply removing it from the culture medium. Due to significant toxic side effects, including DNA damage, teratogenesis, and other reproductive effects (including birth defects and toxicity to sperm), cycloheximide is generally used only in ''in vitro'' research applications, and is not suitable for human use as a therapeutic compound. Although it has been used as a fungicide in agricultural applications, this application is now decreasing a ...
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Dimorphic Fungus
Dimorphic fungi are fungi that can exist in the form of both mold and yeast. This is usually brought about by change in temperature and the fungi are also described as thermally dimorphic fungi. An example is ''Talaromyces marneffei'', a human pathogen that grows as a mold at room temperature, and as a yeast at human body temperature. The term dimorphic is commonly used for fungi that can grow both as yeast and filamentous cells, however many of these dimorphic fungi actually can grow in more than these two forms. Dimorphic is thus often used as a general reference for fungi being able to switch between yeast and filamentous cells, but not necessary limiting more shapes. Ecology of dimorphic fungi Several species of dimorphic fungi are important pathogens of humans and other animals, including ''Coccidioides immitis'', ''Paracoccidioides brasiliensis'', ''Candida albicans'', ''Blastomyces dermatitidis'', ''Histoplasma capsulatum'', ''Sporothrix schenckii'', and ''Emmonsia'' ...
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Asexual Reproduction
Asexual reproduction is a type of reproduction that does not involve the fusion of gametes or change in the number of chromosomes. The offspring that arise by asexual reproduction from either unicellular or multicellular organisms inherit the full set of genes of their single parent and thus the newly created individual is genetically and physically similar to the parent or an exact clone of the parent. Asexual reproduction is the primary form of reproduction for single-celled organisms such as archaea and eubacteria, bacteria. Many Eukaryote, eukaryotic organisms including plants, animals, and Fungus, fungi can also reproduce asexually. In vertebrates, the most common form of asexual reproduction is parthenogenesis, which is typically used as an alternative to sexual reproduction in times when reproductive opportunities are limited. Komodo dragons and some monitor lizards can also reproduce asexually. While all prokaryotes reproduce without the formation and fusion of gametes, m ...
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Rhizoid
Rhizoids are protuberances that extend from the lower epidermal cells of bryophytes and algae. They are similar in structure and function to the root hairs of vascular land plants. Similar structures are formed by some fungi. Rhizoids may be unicellular or multicellular. Evolutionary development Plants originated in aquatic environments and gradually migrated to land during their long course of evolution. In water or near it, plants could absorb water from their surroundings, with no need for any special absorbing organ or tissue. Additionally, in the primitive states of plant development, tissue differentiation and division of labor was minimal, thus specialized water absorbing tissue was not required. The development of specialized tissues to absorb water efficiently and anchor themselves to the ground enabled the spread of plants to the land. Description Rhizoids absorb water mainly by capillary action, in which water moves up between threads of rhizoids and not through ea ...
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Sporangium
A sporangium (; from Late Latin, ) is an enclosure in which spores are formed. It can be composed of a single cell or can be multicellular. Virtually all plants, fungi, and many other lineages form sporangia at some point in their life cycle. Sporangia can produce spores by mitosis, but in nearly all land plants and many fungi, sporangia are the site of meiosis and produce genetically distinct haploid spores. Fungi In some phyla of fungi, the sporangium plays a role in asexual reproduction, and may play an indirect role in sexual reproduction. The sporangium forms on the sporangiophore and contains haploid nuclei and cytoplasm. Spores are formed in the sporangiophore by encasing each haploid nucleus and cytoplasm in a tough outer membrane. During asexual reproduction, these spores are dispersed via wind and germinate into haploid hyphae. Although sexual reproduction in fungi varies between phyla, for some fungi the sporangium plays an indirect role in sexual reprod ...
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Sphere
A sphere () is a Geometry, geometrical object that is a solid geometry, three-dimensional analogue to a two-dimensional circle. A sphere is the Locus (mathematics), set of points that are all at the same distance from a given point in three-dimensional space.. That given point is the centre (geometry), centre of the sphere, and is the sphere's radius. The earliest known mentions of spheres appear in the work of the Greek mathematics, ancient Greek mathematicians. The sphere is a fundamental object in many fields of mathematics. Spheres and nearly-spherical shapes also appear in nature and industry. Bubble (physics), Bubbles such as soap bubbles take a spherical shape in equilibrium. spherical Earth, The Earth is often approximated as a sphere in geography, and the celestial sphere is an important concept in astronomy. Manufactured items including pressure vessels and most curved mirrors and lenses are based on spheres. Spheres rolling, roll smoothly in any direction, so mos ...
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Cytoplasmic Streaming
Cytoplasmic streaming, also called protoplasmic streaming and cyclosis, is the flow of the cytoplasm inside the cell, driven by forces from the cytoskeleton. It is likely that its function is, at least in part, to speed up the transport of molecules and organelles around the cell. It is usually observed in large plant and animal cells, greater than approximately 0.1 mm. In smaller cells, the diffusion of molecules is more rapid, but diffusion slows as the size of the cell increases, so larger cells may need cytoplasmic streaming for efficient function. The green alga genus ''Chara'' possesses some very large cells, up to 10 cm in length, and cytoplasmic streaming has been studied in these large cells. Cytoplasmic streaming is strongly dependent upon intracellular pH and temperature. It has been observed that the effect of temperature on cytoplasmic streaming created linear variance and dependence at different high temperatures in comparison to low temperatures. This ...
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