Crack-smoking
Crack cocaine, commonly known simply as crack, and also known as rock, is a free base form of the stimulant cocaine that can be smoked. Crack offers a short, intense high to smokers. The ''Manual of Adolescent Substance Abuse Treatment'' calls it the most addictive form of cocaine. Crack cocaine first saw widespread use as a recreational drug in primarily impoverished neighborhoods in New York City, Philadelphia, Baltimore, Washington, D.C., Los Angeles, San Francisco, and Miami in late 1984 and 1985; this rapid increase in use and availability was named the "crack epidemic", which began to wane in the 1990s. The use of another highly addictive stimulant drug, crystal meth, ballooned between 1994 and 2004. Physical and chemical properties Purer forms of crack resemble off-white, jagged-edged "rocks" of a hard, brittle plastic, with a slightly higher density than candle wax. Like cocaine in other forms, crack rock acts as a local anesthetic, numbing the tongue or mouth only whe ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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University Of California Press
The University of California Press, otherwise known as UC Press, is a publishing house associated with the University of California that engages in academic publishing. It was founded in 1893 to publish scholarly and scientific works by faculty of the University of California, established 25 years earlier in 1868, and has been officially headquartered at the university's flagship campus in Berkeley, California, since its inception. As the non-profit publishing arm of the University of California system, the UC Press is fully subsidized by the university and the State of California. A third of its authors are faculty members of the university. The press publishes over 250 new books and almost four dozen multi-issue journals annually, in the humanities, social sciences, and natural sciences, and maintains approximately 4,000 book titles in print. It is also the digital publisher of Collabra and Luminos open access (OA) initiatives. The University of California Press publishes ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Crack Ingredients
Crack frequently refers to: * Crack, a fracture in a body * Crack, a fracture (geology) in a rock * Crack, short for crack cocaine Crack may also refer to: Art, entertainment, and media * ''Cracks'' (film), a 2009 independent thriller * Crack Movement, a Mexican literary movement * Crack (band), a Spanish progressive rock group * ''Crack'' (album), an album by Z-RO * ''Cracks'' (album), an album by Nabiha * '' The Crack'', first album by The Ruts * ''Crack Magazine'', a UK-based European music and culture monthly * ''The Crack'' (magazine), a free culture magazine covering the North East of England Slang * Crack, slang for intergluteal cleft Gaining entry * Safe cracking, the process of opening a safe without the combination or the key Software * Crack (password software), a UNIX/Linux password hacking program for systems administrators * Software cracking, a computer program that modifies other software to remove or disable features usually related to digital rights ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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ABC News
ABC News is the news division of the American broadcast network ABC. Its flagship program is the daily evening newscast ''ABC World News Tonight, ABC World News Tonight with David Muir''; other programs include Breakfast television, morning news-talk show ''Good Morning America'', ''Nightline'', ''Primetime (American TV program), Primetime'', and ''20/20 (American TV program), 20/20'', and Sunday morning talk shows, Sunday morning political affairs program ''This Week (ABC TV series), This Week with George Stephanopoulos''. In addition to the division's television programs, ABC News has radio and digital outlets, including ABC News Radio and ABC News Live, plus various podcasts hosted by ABC News personalities. History Early years ABC began in 1943 as the Blue Network, NBC Blue Network, a radio network that was Corporate spin-off, spun off from NBC, as ordered by the Federal Communications Commission (FCC) in 1942. The reason for the order was to expand competition in radi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Parasitic Worm
Parasitic worms, also known as helminths, are large macroparasites; adults can generally be seen with the naked eye. Many are intestinal worms that are soil-transmitted and infect the gastrointestinal tract. Other parasitic worms such as schistosomes reside in blood vessels. Some parasitic worms, including leeches and monogeneans, are ectoparasites thus, they are not classified as helminths, which are endoparasites. Parasitic worms live in and feed in living hosts. They receive nourishment and protection while disrupting their hosts' ability to absorb nutrients. This can cause weakness and disease in the host, and poses a global health and economic problem. Parasitic worms cannot reproduce entirely within their host's body; they have a life cycle that includes some stages that need to take place outside of the host. Helminths are able to survive in their mammalian hosts for many years due to their ability to manipulate the host's immune response by secreting immunomodulato ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Annals Of Emergency Medicine
The ''Annals of Emergency Medicine'' is a monthly peer-reviewed medical journal covering all aspects of emergency medicine care. It is the official journal of the American College of Emergency Physicians (ACEP) and is published on their behalf by Elsevier. The editor-in-chief is Michael L. Callaham (University of California, San Francisco). It was established in 1972 as the ''Journal of the American College of Emergency Physicians'' and obtained its current title in 1980. Abstracting and indexing This journal is abstracted and indexed in: * CINAHL * Scopus * Science Citation Index * Current Contents/Clinical Medicine * Index Medicus/MEDLINE/PubMed According to the ''Journal Citation Reports'', the journal has a 2020 impact factor of 5.721, ranking it first out of 32 journals in the category "Emergency Medicine". In 2009, the BioMedical & Life Sciences Division of the Special Libraries Association The Special Libraries Association (SLA) is an international professional associ ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Levamisole
Levamisole, sold under the brand name Ergamisol among others, is a medication used to treat parasitic worm infections, specifically ascariasis and hookworm infections. It is taken by mouth. Side effects may include abdominal pain, vomiting, headache, and dizziness. Use is not recommended during breastfeeding or the third trimester of pregnancy. Serious side effects may include an increased risk of infection. It belongs to the anthelmintic class of medications. Levamisole was discovered in 1966. It is on the World Health Organization's List of Essential Medicines. It is not commercially available in the United States. Levamisole is also used as a dewormer for livestock. Medical uses Worms Levamisole was originally used as an anthelmintic to treat worm infestations in both humans and animals. Levamisole works as a nicotinic acetylcholine receptor agonist that causes continued stimulation of the parasitic worm muscles, leading to paralysis. In countries that still permit t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Toxic
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell ( cytotoxicity) or an organ such as the liver (hepatotoxicity). By extension, the word may be metaphorically used to describe toxic effects on larger and more complex groups, such as the family unit or society at large. Sometimes the word is more or less synonymous with poisoning in everyday usage. A central concept of toxicology is that the effects of a toxicant are dose-dependent; even water can lead to water intoxication when taken in too high a dose, whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect. Toxicity is species-specific, making cross-species analysis problematic. Newer paradigms and metrics are evolving to byp ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Adulterants
An adulterant is caused by the act of adulteration, a practice of secretly mixing a substance with another. Typical substances that are adulterated include but are not limited to food, cosmetics, pharmaceuticals, fuel, or other chemicals, that compromise the safety or effectiveness of the said substance. It will not normally be present in any specification or declared substances due to accident or negligence rather than intent, and also for the introduction of unwanted substances after the product has been made. Adulteration, therefore, implies that the adulterant was introduced deliberately in the initial manufacturing process, or sometimes that it was present in the raw materials and should have been removed, but was not. An adulterant is distinct from, for example, permitted food preservatives. There can be a fine line between adulterant and additive; chicory may be added to coffee to reduce the cost or achieve a desired flavor—this is adulteration if not declared, but ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mouth
In animal anatomy, the mouth, also known as the oral cavity, or in Latin cavum oris, is the opening through which many animals take in food and issue vocal sounds. It is also the cavity lying at the upper end of the alimentary canal, bounded on the outside by the lips and inside by the pharynx. In tetrapods, it contains the tongue and, except for some like birds, teeth. This cavity is also known as the buccal cavity, from the Latin ''bucca'' ("cheek"). Some animal phyla, including arthropods, molluscs and chordates, have a complete digestive system, with a mouth at one end and an anus at the other. Which end forms first in ontogeny is a criterion used to classify bilaterian animals into protostomes and deuterostomes. Development In the first multicellular animals, there was probably no mouth or gut and food particles were engulfed by the cells on the exterior surface by a process known as endocytosis. The particles became enclosed in vacuoles into which enzymes were secre ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tongue
The tongue is a muscular organ in the mouth of a typical tetrapod. It manipulates food for mastication and swallowing as part of the digestive process, and is the primary organ of taste. The tongue's upper surface (dorsum) is covered by taste buds housed in numerous lingual papillae. It is sensitive and kept moist by saliva and is richly supplied with nerves and blood vessels. The tongue also serves as a natural means of cleaning the teeth. A major function of the tongue is the enabling of speech in humans and vocalization in other animals. The human tongue is divided into two parts, an oral part at the front and a pharyngeal part at the back. The left and right sides are also separated along most of its length by a vertical section of fibrous tissue (the lingual septum) that results in a groove, the median sulcus, on the tongue's surface. There are two groups of muscles of the tongue. The four intrinsic muscles alter the shape of the tongue and are not attached to bone. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Local Anesthetic
A local anesthetic (LA) is a medication that causes absence of pain sensation. In the context of surgery, a local anesthetic creates an absence of pain in a specific location of the body without a loss of consciousness, as opposed to a general anesthetic. When it is used on specific nerve pathways ( local anesthetic nerve block), paralysis (loss of muscle power) also can be achieved. Examples Short Duration & Low Potency Procaine Chloroprocaine Medium Duration & Potency Lidocaine Prilocaine High Duration & Potency Tetracaine Bupivacaine Cinchocaine Ropivacaine Clinical LAs belong to one of two classes: aminoamide and aminoester local anesthetics. Synthetic LAs are structurally related to cocaine. They differ from cocaine mainly in that they have a very low abuse potential and do not produce hypertension or (with few exceptions) vasoconstriction. They are used in various techniques of local anesthesia such as: * Topical anesthesia (surface) * Topical ad ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |