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Corey-Pauling Rules
In biochemistry, the ''Corey-Pauling rules'' are a set of three basic statements that govern the secondary nature of proteins, in particular, the CO-NH peptide link. They were originally proposed by Robert Corey and Linus Pauling Linus Carl Pauling (; February 28, 1901August 19, 1994) was an American chemist, biochemist, chemical engineer, peace activist, author, and educator. He published more than 1,200 papers and books, of which about 850 dealt with scientific top .... The rules are as follows: #The atoms in a peptide link all lie on the same plane. #The nitrogen, hydrogen, and oxygen atoms in a hydrogen bond are approximately in a straight line. #The carbon-oxygen and nitrogen-hydrogen groups are all involved in bonding. References {{reflist Molecular geometry ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Corey
Robert Brainard Corey (August 19, 1897 – April 23, 1971) was an American biochemist, mostly known for his role in discovery of the α-helix and the β-sheet with Linus Pauling. Also working with Pauling was Herman Branson. Their discoveries were remarkably correct, with even the bond lengths being accurate until about 40 years later. The α-helix and β-sheet are two structures that are now known to form the backbones of many proteins. Academic training A childhood polio survivor, Corey received his undergraduate degree from the University of Pittsburgh, and his Ph.D. in chemistry from Cornell University (Marsh, p. 52-53). The findings of α-helix and β-sheet At Caltech, the trio (Pauling, Corey and Branson) published a series of 8 articles in the Proceedings of the National Academy of Sciences (PNAS). The most revolutionary of the 8 articles in PNAS is the one written on February 28, 1951. That date was also Pauling's 50th birthday. It was called "The Structure of Pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Linus Pauling
Linus Carl Pauling (; February 28, 1901August 19, 1994) was an American chemist, biochemist, chemical engineer, peace activist, author, and educator. He published more than 1,200 papers and books, of which about 850 dealt with scientific topics. ''New Scientist'' called him one of the 20 greatest scientists of all time, and as of 2000, he was rated the 16th most important scientist in history. For his scientific work, Pauling was awarded the Nobel Prize in Chemistry in 1954. For his peace activism, he was awarded the Nobel Peace Prize in 1962. He is one of five people to have won more than one Nobel Prize (the others being Marie Curie, John Bardeen, Frederick Sanger and Karl Barry Sharpless). Of these, he is the only person to have been awarded two unshared Nobel Prizes, and one of two people to be awarded Nobel Prizes in different fields, the other being Marie Curie. Pauling was one of the founders of the fields of quantum chemistry and molecular biology. His contributions t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
