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Continuous Erythropoietin Receptor Activator
Continuous erythropoietin receptor activator (CERA) is the generic term for drugs in a new class of third-generation erythropoiesis-stimulating agents (ESAs). In the media, these agents are commonly referred to as 'EPO', short for erythropoietin. CERAs have an extended half-life and a mechanism of action that promotes increased stimulation of erythropoietin receptors compared with other ESAs. Under the trade name Mircera, Roche Pharmaceuticals received approval from the U.S. Food and Drug Administration (FDA) in January 2008 to market a continuous erythropoiesis receptor activator (methoxy polyethylene glycol-epoetin beta) for the treatment of anemia in patients with chronic kidney disease, including in those undergoing dialysis. This issue appears to have been resolved since Fresenius Medical dialysis clinics in the US are now administering this drug.) Methoxy polyethylene glycol-epoetin beta had been approved by the European Commission in August 2007, and was made available i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erythropoiesis-stimulating Agent
Erythropoiesis-stimulating agents (ESA) are medications which stimulate the bone marrow to make red blood cells. They are used to treat anemia due to end stage kidney disease, chemotherapy, major surgery, or certain treatments in HIV/AIDS. In these situations they decrease the need for blood transfusions. The different agents are more or less equivalent. They are given by injection. Common side effects may include joint pain, rash, vomiting, and headache. Serious side effects may include heart attacks, stroke, increased cancer growth, or pure red cell aplasia. It is unclear if use is safe during pregnancy. They work similar to naturally occurring erythropoietin. They were first approved for medical use in the United States in 1989. It is on the World Health Organization's List of Essential Medicines. Commercially available agents include epoetin alfa and darbepoetin alfa, and biosimilars. Use among athletes is prohibited by the World Anti-Doping Agency. Medical uses ESAs are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polka-dot Jersey
The mountains classification is a secondary competition in the Tour de France, that started in 1933. It is given to the rider that gains the most points for reaching mountain summits first. The leader of the classification is named the King of the Mountains, and since 1975 wears the polka dot jersey (french: maillot à pois rouges), a white jersey with red polka dots. History The first Tour de France crossed no mountain passes, but several lesser cols. The first was the col des Echarmeaux (), on the opening stage from Paris to Lyon, on what is now the old road from Autun to Lyon. The stage from Lyon to Marseille included the col de la République (), also known as the col du Grand Bois, at the edge of St-Etienne. The first major climb—the Ballon d'Alsace () in the Vosges — was featured in the 1905 race. True mountains were not included until the Pyrenees in 1910. In that year the race rode, or more walked, first the col d'Aubisque and then the nearby Tourmalet. Both c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rashid Ramzi
Rashid Ramzi ( ar, رشيد رمزي) (born July 17, 1980) is a Moroccan-Bahraini track and field athlete competing internationally for Bahrain in the 800 metres and 1500 metres. Ramzi was investigated by the IAAF after the 2008 Summer Olympics and was stripped of his gold medal for doping. Ramzi was born in Safi, Morocco. After transferring to Bahrain, he ascended to the top of the Asian scene, winning gold medals at the Asian Athletics Championships and the 2002 Asian Games. He set an Asian indoor record over 800 metres to take the silver at the 2004 IAAF World Indoor Championships—his first global medal—and took part in the 2004 Athens Olympics. He reached the peak of his discipline the following year by becoming both the 800 m and 1500 m champion at the 2005 World Championships in Athletics – the first man to ever do such a double at the competition. He failed to retain his titles at the 2007 World Championships, but still took the silver medal over 1500 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood-Horse Publications
Blood-Horse Publications is an American multimedia publishing house focused on horse-related magazines headquartered in Lexington, Kentucky. It began in 1916 through its flagship magazine, ''The Blood-Horse''. From 1961 to 2015, Blood-Horse Publications was owned by the Thoroughbred Owners and Breeders Association, a non-profit organization that promotes Thoroughbred racing and breeding. In 2015, The Jockey Club became the majority owner. According to the company, Blood-Horse has subscribers from over 80 countries worldwide. and according to ESPN is the thoroughbred industry's most-respected trade publication. Executive ;Publisher & CEO * Marla Bickel ;Board of Trustees * Stuart S. Janney III - Chairman * G. Watts Humphrey, Jr. - Vice Chairman * Antony Beck * D. G. Van Clief, Jr. Publications Their book-publishing arm is Eclipse Press. They also distribute a mail-order catalog of horse-related items, called Exclusively Equine that offers publications such as the ''Kentucky Derby ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Equine Test
Equine drug testing is a form of drug testing applied to performance horses in regulated competition. Most common in racehorses, drug tests are also performed on horses in endurance riding and in international competition such as the Olympics and FEI-sanctioned competition. Many horses in a competition sanctioned by various national organizations, such as the United States Equestrian Federation in the USA are also tested for improper drug use. An organization for cooperation and harmonization regarding horseracing is the International Federation of Horseracing Authorities (IFHA) that have several members in over 50 countries worldwide. Before the mid-1980s, the use of high potency performance altering substances in racing was less well controlled due to the inadequacy of analytical technology. Around that time, highly sensitive ELISA testing of horse urine was introduced to racing regulators by a group at the University of Kentucky. This proprietary technology essentially so ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Don Catlin
Don H. Catlin (born June 4, 1938) is an anti- doping scientist and one of the founders of modern drug-testing in sport. Career Catlin has overseen testing for performance-enhancing drugs at the three most recent Olympics held in the United States since the 1984 Summer Games in Los Angeles, as well as testing for the United States Olympic Committee, the National Collegiate Athletic Association (NCAA), Major League Baseball's minor leagues and the National Football League (NFL). He has also developed drug identification techniques currently in use at the Olympic, professional and collegiate levels. In 1982, Catlin founded the UCLA Olympic Analytical Laboratory, the first anti-doping lab in the United States and now the world's largest testing facility of performance-enhancing drugs. He remained the lab's director for 25 years. Catlin currently serves as president and CEO of the Los Angeles-based NGO Anti-Doping Research, Inc. (ADR). The organization was founded in 2005 to bols ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Danilo Di Luca
Danilo Di Luca (born 2 January 1976) is a former Italian professional road racing cyclist, best known for winning the 2007 Giro d'Italia, but also for several positive doping tests, the last of which resulting in a lifetime ban from the sport. Di Luca is also one of six riders to have won each of the three Ardennes classics; he won the Amstel Gold Race and La Flèche Wallonne in 2005, and Liège–Bastogne–Liège in 2007. During his career, Di Luca rode for the Riso Scotti, , , , , , and squads. Di Luca's career was also dogged by numerous infractions, involving three suspensions in relation to doping. In 2007, Di Luca was suspended for three months towards the end of the season, for visiting previously banned doctor Carlo Santuccione, which later escalated into the Oil for Drugs case. In 2009, at the Giro d'Italia, Di Luca tested positive on two occasions for CERA, and was given a backdated – to July 2009 – two-year ban in February 2010, which was later red ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Union Cycliste Internationale
The ''Union Cycliste Internationale'' (UCI; ; en, International Cycling Union) is the world governing body for sports cycling and oversees international competitive cycling events. The UCI is based in Aigle, Switzerland. The UCI issues racing licenses to riders and enforces disciplinary rules, such as in matters of doping. The UCI also manages the classification of races and the points ranking system in various cycling disciplines including road and track cycling, mountain biking and BMX, for both men and women, amateur and professional. It also oversees the World Championships. After the 2022 Russian invasion of Ukraine, the UCI said that Russian and Belarusian teams are forbidden from competing in international events. It also stripped both Russia and Belarus of scheduled events. History UCI was founded in 1900 in Paris by the national cycling sports organisations of Belgium, the United States, France, Italy, and Switzerland. It replaced the International Cycling Associ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Davide Rebellin
Davide Rebellin (9 August 1971 – 30 November 2022) was an Italian professional road bicycle racer, who last rode for UCI Continental team . He was considered one of the finest classic cycle races, classics specialists of his generation with more than fifty top ten finishes in UCI Road World Cup and UCI ProTour classics. Rebellin was best known in the cycling world for his 2004 season, when he won a then unprecedented treble with wins in Amstel Gold Race, La Flèche Wallonne and Liège–Bastogne–Liège. He also won stage races such as Paris–Nice and Tirreno–Adriatico, and a stage in the Giro d'Italia. Rebellin served a two-year suspension for testing positive for Methoxy polyethylene glycol-epoetin beta, Mircera at the 2008 Olympic Games. Career Born in San Bonifacio, province of Verona, Rebellin turned professional in 1992 and came to the attention of the cycling world with a string of strong performances during his early years. He suffered from asthma, a disease that a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Associated Press
The Associated Press (AP) is an American non-profit news agency headquartered in New York City. Founded in 1846, it operates as a cooperative, unincorporated association. It produces news reports that are distributed to its members, U.S. newspapers and broadcasters. The AP has earned 56 Pulitzer Prizes, including 34 for photography, since the award was established in 1917. It is also known for publishing the widely used '' AP Stylebook''. By 2016, news collected by the AP was published and republished by more than 1,300 newspapers and broadcasters, English, Spanish, and Arabic. The AP operates 248 news bureaus in 99 countries. It also operates the AP Radio Network, which provides newscasts twice hourly for broadcast and satellite radio and television stations. Many newspapers and broadcasters outside the United States are AP subscribers, paying a fee to use AP material without being contributing members of the cooperative. As part of their cooperative agreement with the AP, most ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Olympic Committee
The International Olympic Committee (IOC; french: link=no, Comité international olympique, ''CIO'') is a non-governmental sports organisation based in Lausanne, Switzerland. It is constituted in the form of an association under the Swiss Civil Code (articles 60–79). Founded by Pierre de Coubertin and Demetrios Vikelas in 1894, it is the authority responsible for organising the modern ( Summer, Winter, and Youth) Olympic Games. The IOC is the governing body of the National Olympic Committees (NOCs) and of the worldwide "Olympic Movement", the IOC's term for all entities and individuals involved in the Olympic Games. As of 2020, there are 206 NOCs officially recognised by the IOC. The current president of the IOC is Thomas Bach. The stated mission of the IOC is to promote the Olympics throughout the world and to lead the Olympic Movement: *To encourage and support the organization, development, and coordination of sport and sports competitions; *To ensure the regular c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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